• Thymidine Incorporation Assay BrdU offered by a company Thermo Fisher Scientific includes a nucleoside analog that is identified during active DNA synthesis by employing immunohistochemistry. (news-medical.net)
  • The transwell migration assay (a modification of the classical Boyden chamber assay) is frequently utilized to assess endothelial cell migration, which is one of the main in vitro assays in the repertoire of Thermo Fisher Scientific. (news-medical.net)
  • Major players in the multiplex assays market include Luminex Corporation (U.S.), Thermo Fisher Scientific, Inc. (U.S.), Illumina, Inc. (U.S.), Bio-Rad Laboratories, Inc. (U.S.), and QIAGEN N.V. (Netherlands). (pitchengine.com)
  • The Zika Virus NS1 ELISA assay is a highly sensitive and specific assay suitable for the quantitative detection of Zika Virus NS1 in a range of biological samples. (genengnews.com)
  • This ELISA assay can detect NS1 antigen at levels as low as 5 pg/mL and enables researchers to measure the level of Zika NS1 protein in infected patients, offering value in epidemiology studies. (genengnews.com)
  • The Zika Virus IgG/IgM/IgA ELISA assay is designed for the detection of Zika-specific antibodies in human serum. (genengnews.com)
  • Our dedicated biomarker assay team have validated a range of biomarker assays using enzyme-linked immunosorbent assay (ELISA) and electrochemiluminescence (ECL) platforms. (intertek.com)
  • We typically 3-7 days, with sudden onset of myalgia, headache, evaluated ELISA, immunofl uorescence, quantitative reverse and fever that can develop into a severe hemorrhagic transcription PCR, and low-density macroarray assays for detection of CCHF virus using precharacterized archived syndrome ( 4 , 5 ). (cdc.gov)
  • Eagle Biosciences expands their assay portfolio with the introduction of the highly sensitive and affordable Calprotectin ELISA Assay Kit. (prweb.com)
  • Eagle Biosciences is proud to announce the product launch of a brand new Calprotectin ELISA assay kit that offers the widest measurement range of any available assay (1-2000 µg/g stool). (prweb.com)
  • The Calprotectin ELISA assay kit is designed for quick and easy determination of human Calprotectin (neutrophil cytoplasmic protein s100A8/A9, MRP 8/14) in stool samples. (prweb.com)
  • This launch further expands EagleBio's gastrointestinal assay line which already includes Alpha 1 Antitrypsin ELISA, Anti-Gliadin IgG ELISA, Anti-Gliadin sIgA/IgA ELISA, Celiac EmA (Anti- Endomysium Antibody) IgG ELISA , Eosinophil Derived Neurotoxin (EDN) ELISA, Myeloperoxidase (MPO) Stool/Urine ELISA , Rotavirus Antigen ELISA, and Secretory IgA (sIgA) ELISA. (prweb.com)
  • Keefe continued, "I have strong expectations that our Calprotectin ELISA assay kit will become an outstanding tool to researchers in the field. (prweb.com)
  • The use of aptabodies can overcome the obstacles of current immunoblot assays, and these molecules are easily assessable via ELISA systems. (rsc.org)
  • A sensitive, competitive indirect enzyme-linked immunosorbent assay (ELISA) was developed for the detection of triclocarban (TCC) in waters and sediments. (environmental-expert.com)
  • Solid phase capture sandwich ELISA assay using a microwell format. (bio-medicine.org)
  • FLUOROSPOT assays employ sandwich ELISA technology, with fluorescence detection instead of chromogenic detection. (abcam.com)
  • Like the ELISA, the immunofluorescence assay is a test that uses a blood or bone marrow sample to detect the presence of antibodies to the virus. (vetinfo.com)
  • The assay kits are all-inclusive systems, including optimized media for use during cell culture and in preparing test compound treatments, a LRH-1 reference agonist, luciferase detection reagents, and an assay plate. (prweb.com)
  • Browse the product groups below to find reporter assays, a comprehensive range of reporter vectors, luciferase-expressing cell lines and low-toxicity transfection reagents to ensure successful delivery of vectors to the cell line of your choice. (promega.com)
  • Various reagents of a signal producing system may be contained within the device and the necessary liquids added automatically by appropriate instrumentation, so as to have the assay carried out automatically, without technician involvement, providing an accurate and sensitive determination. (google.com)
  • The invention relates to agglutination assays and related kits, reagents and devices. (google.com.au)
  • TUCSON, Ariz., Oct. 1, 2015 (GLOBE NEWSWIRE) -- HTG Molecular Diagnostics , Inc. (Nasdaq:HTGM), a provider of instruments and reagents for molecular profiling applications, announced the availability of the HTG EdgeSeq Immuno-Oncology Assay (research use only) for digitally measuring the mRNA expression of 549 genes implicated in the host immune response to tumors. (cnbc.com)
  • Assays for liquid analytes are performed on a bibulous matrix containing dried reagents which produce a visibly detectable reaction product. (google.es)
  • 5. An assay as in claim 1, wherein the analyte is an enzyme and the reagents include an enzyme substrate which produces an optically detectable change after exposure to the enzyme. (google.es)
  • If the assay involves addition of exogenous reactants (the reagents), then their quantities are kept fixed (or in excess) so that the quantity (and quality) of the target is the only limiting factor for the reaction/assay process, and the difference in the assay outcome is used to deduce the unknown quality or quantity of the target in question. (wikipedia.org)
  • Both the standard qualitative test interpretation (positive, negative, or indeterminate) and the quantitative assay measurements (Nil, TB, and Mitogen concentrations or spot counts) should be reported. (cdc.gov)
  • Among them, in vitro assays have been quantitative and expeditious as initial approximations that warrant further confirmation in vivo . (news-medical.net)
  • To support your submission efficacy claims, robust and meaningful data across complex sample matrices and anticoagulants must be obtained from validated or fit-for-purpose quantitative biomarker assays. (intertek.com)
  • Al‐Nasiry S, Geusens N, Hanssens M, Luyten C and Pijnefnborg R (2006) The use of Alamar Blue assay for quantitative analysis of viability, migration and invasion of choriocarcinoma cells. (els.net)
  • ATCC Cell Proliferation Assay kits are convenient and valuable tools for the quantitative evaluation of a cell population's response to external factors that affect cell viability and growth. (atcc.org)
  • The Emit 2000 Phenytoin Assay is a homogeneous enzyme immunoassay intended for use in the quantitative analysis of phenytoin in human serum or plasma. (bio-medicine.org)
  • Each spot that develops in the assay represents a single reactive cell, providing both qualitative (type of immune protein) and quantitative (number of responding cells) data. (abcam.com)
  • In response to this need, we have developed a rapid platelet-function assay (RPFA), a point-of-care system that provides a quantitative measure of the competence of the GP IIb/IIIa receptor as reflected in the ability of platelets to agglutinate fibrinogen-coated beads. (ahajournals.org)
  • Here, we describe a microprocessor-controlled, whole-blood, cartridge-based, automated version of the assay that provides a quantitative digital display of the results within minutes. (ahajournals.org)
  • Our TaqMan® Assays are primer and probe sets based on 5' nuclease chemistry using TaqMan® MGB (minor groove binder) probes, the most quantitative gene expression technology available. (appliedbiosystems.com)
  • On the other hand, older generation qualitative assays, especially bioassays, may be much more gross and less quantitative (e.g., counting death or dysfunction of an organism or cells in a population, or some descriptive change in some body part of a group of animals). (wikipedia.org)
  • Such early-stage toxicity information requires the development of accurate, reproducible, and predictive in vitro assays. (pnas.org)
  • Thus, the need for concordance between in vitro assays and in vivo responses is becoming greater and more pressing, particularly in high throughput that would enable prioritization of compounds for further development involving animal testing of pharmaceutical candidates ( 13 ) or direct human testing of cosmetic ingredients. (pnas.org)
  • Measure TurboLuc™16 (Tluc16) luciferase activity in mammalian cells with a single reagent-addition step that is for high-throughput screening (HTS) applications using the Thermo Scientific™ TurboLuc™ Luciferase One-Step Glow Assay Kit. (fishersci.com)
  • Lyse adherent cells or pelleted cell suspensions for analysis of promoter expression in luciferase assays with this optimized protein extraction reagent. (fishersci.com)
  • of plastics material having a pore size of 10 microns or greater, through which the applied liquid sample must pass en route to the porous carrier material, the labelled specific binding reagent being freely soluble or dispersible in any liquid sample which enters the macroporous body. (google.com.au)
  • Our protein preparation reagent combines well with any assay to remove interference of any salt, detergent that may interfere. (interchim.com)
  • Any reagent or assay that is spectrally compatible with the Qubit hardware can be adapted for use with the Invitrogen Qubit Fluorometer. (thermofisher.com)
  • The assays include both singleplex and multiplex platforms in multiple matrices, such as plasma, serum, cerebrospinal fluid (CSF) for use in Good Laboratory Practice (GLP) compliant preclinical and clinical development programs. (intertek.com)
  • The multiplex assays market is projected to reach USD 3.76 Billion by 2021 from USD 2.66 Billion in 2016, growing at a CAGR of 7.2% during the forecast period (2016-2021). (pitchengine.com)
  • The adoption of companion diagnostics for increasing safety & efficacy of therapies, need for effective analytical platforms in research to reduce operational costs, advantages of multiplexing over traditional assays are the major drivers for the multiplex assays market. (pitchengine.com)
  • Increasing validation of biomarkers in molecular and protein diagnostics are expected to further drive the growth of the multiplex assays market. (pitchengine.com)
  • However, high cost of multiplex assay instruments will restrain the growth of this market. (pitchengine.com)
  • On the basis of type, the multiplex assays market is categorized into nucleic acid-based assays and protein-based assays. (pitchengine.com)
  • The protein based assays segment is expected to be the fastest growing segment of the multiplex assays market in during the forecast period due to adoption of these assays in research purpose. (pitchengine.com)
  • The technology segment of the multiplex assays market is categorized into multiplex polymerase chain reaction, multiplex arrays, and other technologies. (pitchengine.com)
  • The multiplex arrays segment is expected to account for the largest share of the multiplex assays market in 2016. (pitchengine.com)
  • The advantages of multiplexing over traditional assays, need for effective analytical platforms in research to reduce operational costs, and adoption of companion diagnostics for increasing safety & efficacy of therapy by multiplex assays are driving the growth of this segment. (pitchengine.com)
  • The applications segment of the multiplex assays market is categorized into research & development, diseases & disorders, companion diagnostics, and other applications. (pitchengine.com)
  • Factors such as convenience in performing the assays and faster results offered by multiplex assays are driving the growth of this segment. (pitchengine.com)
  • On the basis of end user, the multiplex assays market is segmented into academic and research institutes, hospitals, clinical laboratories, pharmaceutical and biotechnology companies, and other end users. (pitchengine.com)
  • The pharmaceutical and biotechnology companies segment is estimated to account for the largest share in 2016 due to increased adoption of multiplex assays in this segment. (pitchengine.com)
  • The described assay is a novel gene expression profiling DLBCL classifier based on reverse transcriptase multiplex ligation-dependent probe amplification (RT-MLPA). (elsevier.com)
  • 7. An assay as in claim 1, wherein the analyte is a component of the coagulation pathway and the substrate produces the detectable signal upon activation by said component. (google.es)
  • An assay is an investigative (analytic) procedure in laboratory medicine, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity (the analyte). (wikipedia.org)
  • The measured entity is generally called the analyte, the measurand or the target of the assay. (wikipedia.org)
  • The assay usually aims to measure an intensive property of the analyte and express it in the relevant measurement unit (e.g. molarity, density, functional activity in enzyme international units, degree of some effect in comparison to a standard, etc. (wikipedia.org)
  • Perform firefly luciferase assays in high-throughput screening applications. (fishersci.com)
  • We have developed a miniaturized 3D cell-culture array (the Data Analysis Toxicology Assay Chip or DataChip) for high-throughput toxicity screening of drug candidates and their cytochrome P450-generated metabolites. (pnas.org)
  • High-throughput screening (HTS) assays for toxicity routinely use 96- or 384-well plates with 2D cell monolayer cultures ( 14 , 15 ). (pnas.org)
  • Although miniaturization of 3D platforms has been performed for high-throughput applications ( 20 , 21 ), relatively little effort has been directed toward using 3D cell cultures as screening tools for microscale toxicology assays ( 12 , 22 , 23 ). (pnas.org)
  • Successful assay formats are being made available to academic and commercial organizations for use in high-throughput screening programs that we hope will yield drugs useful in treating human cancers. (cancer.gov)
  • Our group has developed and validated assays suitable for high-throughput screening of libraries of compounds to discover tool molecules and drug candidates. (cancer.gov)
  • Single-site assay devices and multi-site, high-throughput assay devices are disclosed. (freepatentsonline.com)
  • It is a homogenous, highly sensitive, reproducible assay, and adaptable to high-throughput screening. (atcc.org)
  • Canon BioMedical, a wholly owned subsidiary of Canon USA, has launched a line of genotyping assays to detect SNPs, small insertions, and deletions in the human genome. (genomeweb.com)
  • Cell-based assays mimic the mechanism by which the neutralizing antibodies (NAbs) exert their effect in vivo and are the regulatory authorities' preferred method to detect NAb presence. (intertek.com)
  • Each assay must be target specific, reproducible, minimally affected by matrix effects, and be able to detect the NAb in the presence of the therapeutic. (intertek.com)
  • We were able to detect FISH-confirmed aberrations in several key cancer genes including ERBB2, MDM2, EGFR, and MYC suggesting that OncoScan FFPE Assay Kit can be considered a viable higher resolution and higher specificity alternative to FISH testing for confirmation of cancer gene aberrations in solid tumor tissue. (aol.com)
  • In addition, the ability to detect a range of clinically relevant somatic mutations adds even more value to the assay and analysis. (aol.com)
  • The issue with monitoring is that, in addition to platelet and haemoglobin levels being typically normal, the assays for ADAMTS13 are insufficiently sensitive to detect low levels. (medscape.com)
  • The assay was also able to detect the MYD88 L265P mutation, one of the most common genetic abnormalities found in ABC DLBCLs. (elsevier.com)
  • The assay consists of three separate tests that detect O and H antigens simultaneously, including the ability to identify some serotype-specific markers in the Additional Targets or AT test. (luminexcorp.com)
  • These assays follow different parameters to determine the rate of cell proliferation like rate of deoxyribonucleic acid synthesis, metabolic activity of cells, different antigens associated with cell proliferation and adenosine triphosphate concentration. (els.net)
  • Cell proliferation assays are mainly designed based on three concepts, that is, (1) measuring rate of DNA replication, (2) analysis of metabolic activity and (3) cell surface antigen recognitions. (els.net)
  • The MTT assay measures metabolic activity, while SRB and CVE are protein-staining assays. (scirp.org)
  • The advantage of these assays arises from the fact that they measure different parts of the cell, namely protein content and metabolic activity. (scirp.org)
  • The Bradford protein assay was developed by Marion M. Bradford in 1976. (wikipedia.org)
  • Under acidic conditions, the red form of the dye is converted into its blue form, binding to the protein being assayed. (wikipedia.org)
  • Unlike other protein assays, the Bradford protein assay is less susceptible to interference by various chemical compounds such as sodium, potassium or even carbohydrates like sucrose, that may be present in protein samples. (wikipedia.org)
  • Angiogenic inducers (such as VEGF recombinant mouse or rat protein, TGFB1 recombinant human protein or PDGF-BB recombinant mouse or human protein) are often added to the CAM assays. (news-medical.net)
  • However, translating this promise into easy to use and multilplexed protein assays, which are highly sought after in molecular diagnostics such as cancer diagnosis and treatment monitoring, has been challenging. (pnas.org)
  • Magnetic nanotag-based protein detection assay. (pnas.org)
  • The assays were applied in various enzyme isolation and characterisation studies, using crude protein solutions as well as purified enzyme in pH-dependence, substrate and inhibitor specificity investigations. (hindawi.com)
  • Addressing the need to define steadfast analytical performance criteria for prion amyloid seeding assays (ASAs), researchers developed a method to measure prion protein conversion time (from normal cellular form to prion form) by a combination of statistical analyses to obtain a prion-detecting ASA with a known degree of confidence. (medicalnewstoday.com)
  • Find the right protein assay for your application. (interchim.com)
  • Whether you need a deep and broad high-resolution transcriptome profile, or are focused on gene-level changes on the surface of the transcriptome, Clariom assays generate reproducible data and offer the level of coverage you need to find biomarkers. (thermofisher.com)
  • Ideal for assays requiring site-directed orientation of a biomolecule, especially antibodies. (corning.com)
  • Ideal for assays requiring site-directed orientation of a biomolecule (oxidized antibodies, carbohydrates, and glycosylated proteins) while maintaining enzymatic or immunological activity. (corning.com)
  • Most cTn assays are sandwich immunoassays that use either monoclonal or polyclonal antibodies. (ahajournals.org)
  • The absolute concentrations of cTnI are currently not comparable between manufacturers because of the different antibodies used in the cTnI assays. (ahajournals.org)
  • Cytotoxic T Cells can be cultured with activating antibodies such as anti-CD3 and tested for their ability to kill tumor targets in an IncuCyte based assay. (criver.com)
  • Biomarker assays are also useful for identifying intermediate endpoints of success to decrease follow-up time. (intertek.com)
  • The use of a specific biomarker assay can provide an early indication of drug efficacy. (intertek.com)
  • By selecting Intertek, you gain a partner with extensive experience in biomarker assays. (intertek.com)
  • Our center of excellence, founded in 1999 located in San Diego, California, USA, is recognized as one of the leading biomarker assay laboratories in the world. (intertek.com)
  • Dr Alwan said: "Anti-platelet therapy decreases thrombus formation and works synergistically to improve thrombus surface coverage before and after prophylaxis, and this newly developed assay can be used as a biomarker to assess treatment options and efficacy in congenital TTP. (medscape.com)
  • Even after intense efforts at quality control, biomarker readings using laboratory-grade assays swing widely between different labs, batches, and runs. (alzforum.org)
  • It is our hope that the assay we have developed, which addresses an important recommendation of the recent WHO classifications, will contribute to better management of these tumors and improved patient outcomes. (elsevier.com)
  • Cell viability assays, including techniques to assess the proliferation of cancer cell lines, constitute a rapid, inexpensive and sensitive screening method to pre-clinically evaluate the activity of a potential drug or substance. (scirp.org)
  • To this end, cell viability assays are the most common method used as a primary indicator of a given substance's cytotoxicity. (scirp.org)
  • Labs will be able to run their LDTs simultaneously with commercially available IVD assays, and results will release automatically to laboratory information systems. (genomeweb.com)
  • Those assays that are very highly commercially demanded have been well investigated in research and development sectors of professional industries, undergone generations of development and sophistication, and become copyrighted intellectual properties via highly competitive process patenting. (wikipedia.org)
  • Luminex ® Assays offer our widest selection of analytes for bead-based multianalyte profiling using cell culture supernates, serum, or plasma samples. (rndsystems.com)
  • Build your panel yourself from our menu of over 450 analytes or browse our selection of suggested Luminex Assay panels. (rndsystems.com)
  • At launch the firm will market 103 pre-designed assays as well as an "open" chemistry for researchers to customize, as reported by GenomeWeb. (genomeweb.com)
  • INDIGO offers both screening services and assay kits for the pharmaceutical, biotechnology, agri-business, nutriceutical industries, as well as government research agencies and academic researchers. (prweb.com)
  • Researchers from the University of Würzburg in Germany and from Queen's University Belfast in the UK have developed a fluorimetric antibiotic screening assay based on a Beckman Coulter Inc. capillary electrophoresis system that includes equipment for fluorescence excitation and detection, and on Live/Dead BacLight fluorescence-labeling kits from Invitrogen Corp. of Carlsbad, Calif. (photonics.com)
  • To prove that the capillary electrophoresis method works, the researchers measured the efficacy of various antibiotics on two strains of bacteria and compared the results to those measured with a Varian fluorescence microplate reader and with a classical microbiology assay. (photonics.com)
  • GLASGOW - Combining prophylactic infusions and anti-platelet therapy normalises thrombus formation in patients with congenital thrombotic thrombocytopenic purpura (TTP) under shear flow conditions, reveals a novel assay developed by UK researchers that could revolutionise both the diagnosis and management of this rare condition. (medscape.com)
  • With this new immuno-oncology assay, researchers can measure the expression levels of drug targets, determine tumor infiltrate composition, and assess total immune cell composition using just a single section of FFPE tissue," stated Chris Roberts, HTG's Senior Vice President of Marketing and Medical Innovation. (cnbc.com)
  • In a report in The Journal of Molecular Diagnostics , researchers describe their development of a reliable, accessible, rapid, and cost-effective new gene expression signature assay that can enhance lymphoma management by helping to match tumors with the appropriate targeted therapy. (elsevier.com)
  • An immune-based assay can rapidly distinguish between latent and active TB even in the absence of mycobacteria in the sputum, researchers said. (medpagetoday.com)
  • Then the researchers used an automated assay to determine the cutoffs that predicted amyloid positivity in the BioFINDER cohort, applied the correction factor, and found that the same cutoffs correctly identified ADNI participants with brain amyloid accumulation. (alzforum.org)
  • Moreover, binding assays have been useful in examining the effects of drugs and disease on neurotransmitter receptors, and the procedure has been adapted for use as a simple and sensitive analytical method for measuring the concentration of neurotransmitters and drugs. (springer.com)
  • In order to fully exploit the potential of receptor binding assays and to avoid the misinterpretation of data, it is essential to have an understanding of the fundamental principles that govern this procedure. (springer.com)
  • Forty-seven breast cancer tissue samples were available with EGFR values previously determined in radio-ligand binding assays. (hindawi.com)
  • Results with this rapid platelet-function assay (RPFA) correlate well with results of traditional turbidimetric platelet aggregometry using citrated platelet-rich plasma (PRP) and radiometric binding assays of GP IIb/IIIa receptor occupancy. (ahajournals.org)
  • Magnetic nanotags (MNTs) are a promising alternative to fluorescent labels in biomolecular detection assays, because minute quantities of MNTs can be detected with inexpensive giant magnetoresistive (GMR) sensors, such as spin valve (SV) sensors. (pnas.org)
  • Comparison of SNP-Based Detection Assays for Food Analysis: Coffe. (ingentaconnect.com)
  • The incubation period is serologic and molecular assays for diagnosis of CCHF. (cdc.gov)
  • We decided to put theranostics on the program because of the success of a few drugs in the marketplace right now that are targeted and based on molecular assays," Dr. Berg told CAP TODAY. (cap.org)
  • Here, we provide a survey of strategies used for the selection, design and use of hyperpolarized NMR probes in biological assays, and describe current limitations and developments. (mdpi.com)
  • Lerche, M.H. Hyperpolarized NMR Probes for Biological Assays. (mdpi.com)
  • The present invention relates to the detection of the energy of photons from biological assays, including those giving rise to characterisitic transmission, reflectance and absorbance spectra. (google.co.uk)
  • Your search returned 768 Apoptosis Caspase Assay Cell Viability and Proliferation across 19 suppliers. (biocompare.com)
  • Gorczyca W, Bruno S, Darzynkiewicz RJ, Gong J, Darzynkiewicz Z. (1992) DNA strand breaks occurring during apoptosis: Their early in situ detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors. (wikipedia.org)
  • CS1 maint: Multiple names: authors list (link) Darzynkiewicz, Z, Galkowski, D, Zhao, H. (2008) Analysis of apoptosis by cytometry using TUNEL assay. (wikipedia.org)
  • The most reliable among them calculates proliferation by direct measurement of DNA synthesis, and thymidine incorporation assay is often cited as a reference model. (news-medical.net)
  • Ahmed SA, Gogal RM and Walsh JE (1994) A new rapid and simple nonradioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H]thymidine incorporation assays. (els.net)
  • These probes are readily used directly under natural conditions in biofluids and are often directly developed and optimized for cellular assays, thus leaving little doubt about their specificity and utility under biologically relevant conditions. (mdpi.com)
  • Depending on the respective analytical task, both assays complement each other. (hindawi.com)
  • You should contact one of the staff at Assay Services unit detailing about your analytical needs. (wisc.edu)
  • Microsomal assays primarily assess metabolism by the cytochrome P450 system (phase I enzymes) while hepatocyte assays more broadly assess the overall cellular metabolism of the test compound (phase I and phase II enzyme pathways). (sigmaaldrich.com)
  • The present invention relates to assays involving specific binding, especially immunoassays. (google.com.au)
  • The present invention relates to an assay for determining the motility of cells. (freepatentsonline.com)
  • Other in vitro angiogenesis assays that cover all angiogenic functions ( i.e. proliferation, migration, tube formation) include mouse metatarsal assay, embryoid assay and others. (news-medical.net)
  • Therefore, cell proliferation assays become crucial to scrutinise the rate of cell proliferation in both in vitro and in vivo conditions. (els.net)
  • In the present article, authors have tried to summarise different cell proliferation assays commonly used in laboratories to determine cell proliferation. (els.net)
  • Cell proliferation antigen‐based assay targets antigens present in proliferating cells such as markers like Ki‐67, topoisomerase IIB, phosphohistone H3 and PCNA. (els.net)
  • Cell proliferation assay using 3 H‐thymidine nucleotide incorporation and radioactive measurements. (els.net)
  • Scheme of antigen‐based cell proliferation assay. (els.net)
  • The CVE assay represents a quick method to determine cell proliferation. (scirp.org)
  • Is a resazurin-based cell proliferation assay that is sensitive and non-toxic. (atcc.org)
  • Application of electrical lysis for an enzymatic assay. (nih.gov)
  • We previously developed an assay sensitive to GP IIb/IIIa receptor blockade based on the ability of platelets in whole blood to agglutinate fibrinogen-coated beads when activated by a thrombin receptor-activating peptide. (ahajournals.org)
  • As an example of a successful application of theranostics, Dr. Berg chose the use of assays to identify patients with non-small-cell lung cancer who have mutations in the gene for epidermal growth factor receptor, or EGFR. (cap.org)
  • This surface covalently couples to animated single-stranded DNA by either the 5' or 3' end, making it suitable for hybridization assays, amplification, and other DNA assays. (corning.com)
  • Cell-based neutralizing antibody assays can be difficult to develop as the selection of the most suitable assay type (indirect or direct) and format depends on thorough understanding of the drug's mechanism of action. (intertek.com)
  • To conduct a detailed kinetic investigation of QC catalysis, we developed coupled continuous assays suitable for microplates which allow now convenient determination of QC activity. (hindawi.com)
  • Biomarkers assays are becoming increasingly important in clinical development. (intertek.com)
  • The assays utilize a multi-purpose diluent that allows up to 50 biomarkers to be simultaneously profiled. (rndsystems.com)
  • Clariom assays, built using the latest transcriptome knowledge from multiple databases, are simple and fast tools for finding high-fidelity expression biomarkers. (thermofisher.com)
  • We believe the expanding trend in the development of immuno-oncology therapies will continue, and this new assay can be a valuable tool in the research of tumor biomarkers in tissue and liquid biopsies. (cnbc.com)
  • 20. The use according to any preceding claim, where light is transmitted to the cryogenic detector using a networked optical fibre from more than one biological or diagnostic assay. (google.co.uk)
  • The short term reproduction assay was validated in the fathead minnow (Pimephales promelas) and this is the recommended species. (oecd.org)
  • A modified tier 1 EDSP 21‐day fish short‐term reproduction assay (FSTRA) was used to evaluate the effects of sediment exposure from freshwater and brackish ponds in Bermuda on reproductive fecundity and endocrine function in fathead minnow (pimephales promelas) and killifish (fundulus heteroclitus). (environmental-expert.com)
  • The fish short term reproduction assay (FSTRA) is a key component of the USEPA endocrine disruptor screening program (EDSP), which uses a weight‐of‐evidence analysis based on data from several assays to identify the potential for chemicals to act as agonists or antagonists of the estrogen or androgen receptors (ER, AR), or inhibitors of steriodogenic enzymes. (environmental-expert.com)
  • ASSAY and Drug Development Technologies delivers access to the techniques and tools that enable new advances in early-stage screening, and lead to therapeutic compounds for drug discovery and development. (liebertpub.com)
  • Our experts, based in Good Laboratory Practice (GLP) compliant laboratories, evaluate each therapeutic, conduct tailored assay development and ensure that each assay is optimized to suitably determine the presence of NAb with maximum possible level of drug tolerance. (intertek.com)
  • AFFX ) announced the launch of the new OncoScan™ FFPE Assay Kit , a whole-genome copy number assay for highly degraded FFPE solid tumor samples, at the Cancer Cytogenomics Microarray Consortium conference being held in Chicago this week. (aol.com)
  • This new product provides whole-genome copy number data with specifically enhanced high resolution in approximately 900 known cancer genes, loss of heterozygozity (LOH) across the whole genome as well as clinically relevant somatic mutation data − all from a single assay. (aol.com)
  • Because OncoScan FFPE Assay Kit has whole-genome resolution, we also obtained valuable incremental copy number aberrations in these samples. (aol.com)
  • The assay has been designed for retrospective gene expression profiling to complement traditional immunohistochemistry (IHC) testing. (genomeweb.com)
  • Overall, the RT-MLPA assay correctly assigned 85.0% of the cases into the expected subtypes compared to 78.8% with immunohistochemistry. (elsevier.com)
  • They were precisely quantified using highly sensitive digital PCR assays to analyze amplification of EGFR, MET, FGFR3, MYC, ERBB2, and MYCN genes at +3, +6, and +12 copies against a single well-characterized genomic background, the company said. (genomeweb.com)
  • To discuss assays for EGFR mutations, Dr. Berg invited Neal Lindeman, MD, associate pathologist for clinical chemistry and molecular diagnostics in the Department of Pathology at Brigham and Women's Hospital and instructor of pathology at Harvard Medical School. (cap.org)
  • To Dr. Lindeman a more practical question in molecular pathology now is which assay to use for EGFR. (cap.org)
  • The big question for us is whether we should continue to do complete DNA sequence analysis [for the EGFR gene] or to make more of a shortcut assay to look only for known mutations," he says. (cap.org)
  • MyQubit brings your favorite fluorescence assays right to your benchtop, providing a reliable platform for many quantitation needs-from laboratory research and quality control to process monitoring and beyond. (thermofisher.com)
  • 6. An assay as in claim 5 wherein the optically detectable change is fluorescence, luminescence, or color change. (google.es)
  • The cardiac isoforms of cTnI and cTnT have additional unique N-terminal amino acid sequences, which allows for specific antibody and assay development and detection of each component in the bloodstream. (ahajournals.org)
  • 5. A diagnostic disposable device according to claim 1, wherein said housing has a trough, an inlet port and a gas release port for said trough, unconnected with said assay system for receiving priming or other waste fluid. (google.com)
  • 2. An assay as in claim 1 wherein the sample volume is from 3 μl to 50 μl. (google.es)
  • 3. An assay as in claim 1, wherein the sample is a patient sample. (google.es)
  • 10. An assay as in claim 1, wherein the production of signal is detected at a plurality of time points over a preselected time duration. (google.es)