Lipid-laden alveolar macrophages, also known as pulmonary foam cells, are cells found in bronchoalveolar lavage (BAL) specimens that consist of macrophages containing deposits of lipids (fats). (wikipedia.org)
The lipid content of the macrophages can be demonstrated using a lipid targeting stain like Oil Red O or Nile red. (wikipedia.org)
Increased levels of lipid-laden alveolar macrophages are associated with various respiratory conditions, including chronic smoking, gastroesophageal reflux, lipoid pneumonia, fat embolism, pulmonary alveolar proteinosis and pulmonary aspiration. (wikipedia.org)
Lipid-laden alveolar macrophages have been reported in cases of vaping-associated pulmonary injury. (wikipedia.org)
The lipid-laden macrophage index (LLMI) can be calculated by counting 100 macrophages in a BAL specimen treated with a lipid stain and scoring each macrophage from 0 to 4 based on the amount of lipids present in the cell. (wikipedia.org)
However, the test is limited by poor reproducibility and low specificity for pulmonary aspiration, as lipid-laden macrophages occur in many respiratory conditions. (wikipedia.org)
The diagnosis of hydrocarbon intoxication was based on bronchoalveolar lavage results, neutrophilic alveolitis with the presence of lipid-laden macrophages , and evidence of lipoid pneumonia from the autopsy performed on one victim. (lookfordiagnosis.com)
RESULTS: Histologically the macrophages appeared filled with lipid and were similar to atherosclerotic foam cell macrophages . (lookfordiagnosis.com)
Polarization of the macrophages regulates the production of proinflammatory and pro-resolving lipid mediators (LMs) to mediate acute inflammation and its resolution in a time-dependent manner. (cdc.gov)
Pneumonia11
Exogenous lipid pneumonia related to smoking weed oil following cadaveric renal transplantation . (lookfordiagnosis.com)
Two bronchoalveolar lavages were nondiagnostic, and an open lungbiopsy was performed, which revealed a pulmonary alveolar proteinosis (PAP) reaction and exogenous lipid pneumonia (ELP). (lookfordiagnosis.com)
Background: Aspiration pneumonia remains a significant and often devastating problem in critically ill patients. (the-medical-dictionary.com)
It is unclear whether aspiration pneumonia occurs because of problems in the handling of oropharyngeal secretions or if the reflux of gastric contents is the major etiological factor. (the-medical-dictionary.com)
Finally, the impact and contribution of tubes, both endotracheal and nasoenteral, on aspiration pneumonia is unclear. (the-medical-dictionary.com)
Understanding of the dynamic changes in gastrointestinal motility will also be an important factor to decrease the incidence of aspiration pneumonia in this patient population. (the-medical-dictionary.com)
This article will review the normal physiology and the threats to that normal function commonly seen in severely ill patients that may contribute to aspiration pneumonia. (the-medical-dictionary.com)
reported that bile acid aspiration induced severe chemical pneumonitis in a porcine lung model [ 14 ]. (hindawi.com)
Needle15
The aspiration and biopsy are done by a trained medical practitioner (nurse or doctor) using a small needle inserted into a bone. (kidshealth.org)
For the bone marrow aspiration, the doctor or nurse will carefully insert a needle into the biopsy site and will then attach a syringe to draw out a sample of fluid from inside the bone. (kidshealth.org)
Quickly spread the lipid solution over the entire Teflon surface using the syringe needle. (avantilipids.com)
These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
Fine-needle aspiration cytology plays a vital role in evaluation of mediastinal lesions. (allenpress.com)
Fine-needle aspiration cytology (FNAC) was first introduced by Martin and Ellis 4 and has been used as an easy and safe procedure for diagnosing primary and metastatic mediastinal diseases. (allenpress.com)
Fine-needle aspiration cytology of the mediastinum can be highly reliable, with greater than 80% diagnostic accuracy. (allenpress.com)
Both Dr. Nelson and Dr. Nath are trained in diagnostic thyroid ultrasounds and thyroid fine needle aspirations that will be offered at this center if indicated. (sjcphysiciannetwork.com)
Dr Ng is well-versed in the management of Diabetes Mellitus (Type1, Type2 and Gestational diabetes mellitus), Lipid/Cholesterol disorders, Thyroid disorders, including the use of ultrasound-guided fine needle aspiration (FNA) of thyroid nodules, Testosterone deficiency, Polycystic Ovarian Syndrome, Investigation of Hirsutism and Gynaecomastia, Endocrine Causes of Secondary Hypertension and Pituitary and Adrenal disorders. (parkwayshenton.com.sg)
For peripheral lesion evaluation, consider alternative diagnostic approaches (eg, image-guided needle aspiration). (medscape.com)
Surgical drainage should be considered only when needle aspiration is unsuccessful, because an operation may damage the breast bud and result in reduction of adult breast size. (medscape.com)
Treatment involves antibiotics, needle aspiration, or surgical drainage. (medscape.com)
For this reason, needle aspiration is the preferred treatment. (medscape.com)
Thus, it seems that the effects of this carbohydrate subtype on lipid metabolism should be carefully examined in human studies. (biomedcentral.com)
Micropipette1
Using the aspiration micropipette approach, the effect of mechanical stretching of microplastics on live cell membranes was demonstrated on red blood cells. (ad4sc.com)
Nanoparticles2
Lipid Nanoparticles: Are They Subtly Changing Human Beings? (substack.com)
But it is the lipid nanoparticles (LNPs) in the mRNA injections that keep me up nights, feeling that the dystopia on earth has now fully arrived. (substack.com)
Biopsy4
The person performing the bone marrow aspiration and biopsy will know your child's medical history, but might ask additional questions, such as what medicines your child is taking or whether he or she has any allergies. (kidshealth.org)
Numbing cream may be placed on the aspiration and biopsy site about 30 minutes before the procedure. (kidshealth.org)
A bone marrow aspiration and biopsy usually takes about 30 minutes. (kidshealth.org)
Some kids feel a quick sharp cramp as the liquid bone marrow is withdrawn for the aspiration or as the sample of bone marrow is removed for the biopsy. (kidshealth.org)
Meconium6
Meconium aspiration syndrome (MAS) is the aspiration of stained amniotic fluid, which can occur before, during, or immediately after birth. (medscape.com)
Because meconium is rarely found in the amniotic fluid prior to 34 weeks' gestation, meconium aspiration primarily affects infants born at term and postterm. (medscape.com)
However, the most severe complication of meconium passage in utero is perinatal aspiration of stained amniotic fluid (before, during, or immediately after birth)-ie, meconium aspiration syndrome (MAS). (medscape.com)
Aspiration of meconium-stained amniotic fluid may occur if the fetus is in distress, leading to a gasping breathing pattern. (medscape.com)
Enzymes, bile salts, and free fatty acids in meconium irritate the airways and parenchyma, causing a release of cytokines (including tumor necrosis factor (TNF-α, interleukin (IL)-1β, IL-6, IL-8, IL-13), which initiate a diffuse pneumonitis that may begin within a few hours of aspiration. (medscape.com)
To complicate matters further, many infants with meconium aspiration syndrome (MAS) have primary or secondary persistent pulmonary hypertension of the newborn (PPHN) as a result of chronic in utero stress and thickening of the pulmonary vessels. (medscape.com)
Pulmonary2
A LLMI score greater than 100 is considered positive for pulmonary aspiration. (wikipedia.org)
This aspiration induces hypoxia via four major pulmonary effects: airway obstruction, surfactant dysfunction, chemical pneumonitis, and pulmonary hypertension. (medscape.com)
Membranes2
Lipid bilayer membranes are among the most ubiquitous structures in the living world, with intricate structural features and a multitude of biological functions. (nature.com)
While the health implications of digesting microplastics on living organisms are debatable, we have uncovered a physical mechanism for the mechanical stretching of model cell lipid membranes induced by adsorbed micrometre-sized microplastic particles that are ubiquitous in oceans. (ad4sc.com)
Consumption1
The relationship between seeds consumption, lipid profile and body mass index among patients with cardiovascular diseases. (greenmedinfo.com)
Proteins2
the remaining 5-15% of ingredients consists of solid constituents, primarily intestinal secretions, mucosal cells, and solid elements of swallowed amniotic fluid, such as proteins and lipids. (medscape.com)
For the case of glutaraldehyde, this chemical is a non-specific fixative that promotes the cross-link of the membrane skeletal proteins, phospholipids in the membrane and cytoplasm and consequently it promotes the increase of the shear modulus and viscosity of the entire cell, including the cytoplasm and lipid membrane [11]. (webmedcentral.com)
Bile2
This marked increase in biliary lipid secretion was not followed by a change in molar composition of biliary lipids and lithogenicity of bile. (satco.hu)
After allowing four hours for gall bladder contraction and stabilisation of hepatic bile secretion hourly samples were obtained for the following six hours from the second proximal and the distal outlet by continuous aspiration. (satco.hu)
Accumulation1
These data indicate that replacement of 5.4% of total dietary carbohydrate with RS significantly increased post-prandial lipid oxidation and therefore could decrease fat accumulation in the long-term. (biomedcentral.com)
Composition2
Writing ( Fig. 1a-b ), Dynamic control of composition ( Fig. 1c-d ), Erasing ( Fig. 1e ) and Localized lipid film modification and decoration ( Fig. 1f-g ). 2D-networks are directly written by providing liposomes through the pipette, while simultaneously translating the substrate by means of a motorized stage. (nature.com)
Diffusively continuous fluidic networks can be produced in this way, where the topology is defined by the x, y scanning sequence and the composition depends on the lipids supplied by the pipette. (nature.com)
Cardiovascular1
Do not routinely order expanded lipid panels (particle sizing, nuclear magnetic resonance) as screening tests for cardiovascular disease. (medscape.com)
Bone3
Bone marrow aspirations and biopsies are performed to examine bone marrow, the spongy liquid part of the bone where blood cells are made. (kidshealth.org)
In a bone marrow aspiration , a small amount of liquid marrow is taken from inside the bone so the cells can be examined under a microscope. (kidshealth.org)
Doctors perform bone marrow aspirations and biopsies when they're concerned about a problem in the bone marrow. (kidshealth.org)
Technique1
Biliary lipid secretion was measured by the intestinal perfusion technique described by Grundy and Metzger.12 The evening before the study the subjects were admitted to the Metabolic Ward where they swallowed a triple lumen tube. (satco.hu)
Cell2
Laboratory analysis included free lipid volume, viability via lipolysis and propidium iodide staining, and cytological analysis, including cell surface protein examination and hematoxylin and eosin staining. (yoursurgery.com)
We are particularly interested in studying lipid-specific CD1a-reactive T cell responses and their role in skin inflammation. (ox.ac.uk)
Preparation1
The effect of Rowachol (200 mg tid), an essential oil preparation, on biliary lipid secretion and serum lipids was measured in six healthy male volunteers before and after four weeks of treatment. (satco.hu)
Role1
Alterations of endocannabinoid system in adipose tissue play an important role in lipid regulation and metabolic dysfunction associated with obesity. (biomedcentral.com)
Effect2
Phospholipids include phosphatidylcholine (PC), sphingomyelin (SM), inositol lipid (PI), and lysophosphatidyl choline (LPC), among which LPC is the main component of oxidized low density lipoprotein (LDL) and degrades production of PC with its cytotoxic effect [ 10 ]. (hindawi.com)
Nevertheless, it has little effect on the cytoplasmic or lipid membrane viscosity. (webmedcentral.com)
Here she discusses her experience and aspirations for the future of her research. (ox.ac.uk)
What are your aspirations for the future of this research? (ox.ac.uk)
Increase1
It is possible that strong physical association between RS and dietary lipid may slow the absorption, and thereby increase the oxidation, of dietary lipid. (biomedcentral.com)
Weeks1
Biliary lipid secretion rates were measured before and after four weeks of administration of Rowachol (200 mg tid). (satco.hu)
Film3
Cover the beaker loosely with Parafilm and prehydrate the lipid film with a warm (45-50 °C) water-saturated argon/nitrogen jet for 15 minutes. (avantilipids.com)
10 °C). Using a disposable plastic syringe fitted with a 0.2 or 0.45 mm syringe filter, gently add the rehydration buffer onto the pre-hydrated lipid film. (avantilipids.com)
During the incubation period, the lipid film will swell and strip away from the Teflon surface to form small "clouds" of vesicles. (avantilipids.com)
Analysis1
Serum was separated and stored at -20°C until serum lipid analysis. (satco.hu)
Hours1
Remove the volatile organic solvents from the lipid by placing the beaker in vacuo for at least 2 hours. (avantilipids.com)