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AspergillusAspergillus fumigatusAspergillosisAspergillus flavusAspergillus nigerAspergillus nidulansAntifungal AgentsLung Diseases, FungalSpores, FungalDNA, FungalPulmonary AspergillosisItraconazoleEchinocandinsFungiAmphotericin BInvasive Pulmonary AspergillosisAspergillus ochraceusOchratoxinsTriazolesMycosesAflatoxinsAspergillosis, Allergic BronchopulmonaryMannansMycologyAntigens, FungalPenicilliumDrug Resistance, FungalEye Infections, FungalMicrobial Sensitivity TestsOpportunistic InfectionsFungal ProteinsMycological Typing TechniquesPeptides, CyclicCandidaHyphaeVitamin K 3RNA, Ribosomal, 18SGenes, FungalImmunocompromised HostRNA, Ribosomal, 5.8SDNA, Ribosomal SpacerLeptospermumArachis hypogaeaMycotoxinsLipopeptidesPyrimidinesMucoralesFusariumTetrazolium SaltsMycetomaColorimetryMolecular Sequence DataCulture MediaAntibodies, FungalSpecies SpecificitySterigmatocystinKeratitisPolymerase Chain ReactionCandidiasisGlucan 1,4-alpha-GlucosidaseBronchoalveolar Lavage FluidSensitivity and SpecificityBase SequenceSequence Analysis, DNAGene Expression Regulation, FungalCandida albicansHematologic NeoplasmsPhylogenyDNA PrimersGliotoxinLung
FumigatusFlavusPenicilliumGenusGenomesNidulansFungusNigerIsolatesCandidaOryzaeGenesRhizopusStrainsAflatoxin productionInfectionMoldAspergillosisFungi speciesAlternariaVersicolorKwon-ChungCystic fibrosisMicrobiologyConidialSporesAflatoxinsAmazonicusOrganismsPathogensPulmonaryHorieTaxonomicReactiveCarcinogenicAdvantageousSignificantlyExtractsInflammationAntimicrobialDifferent speciesSevereInvasiveClinicalERMIIndoorBacterial speciesStudyInfections
Fumigatus16
  • Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species. (jcvi.org)
  • Some Aspergillus species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions and life-threatening systemic infections in humans. (jcvi.org)
  • The genera Aspergillus and Penicillium include some of the most beneficial as well as the most harmful fungal species such as the penicillin-producer Penicillium chrysogenum and the human pathogen Aspergillus fumigatus, respectively. (umd.edu)
  • Here we report the complete sequence and annotation of the mitochondrial genomes of six Aspergillus and three Penicillium species: A. fumigatus, A. clavatus, A. oryzae, A. flavus, Neosartorya fischeri (A. fischerianus), A. terreus, P. chrysogenum, P. marneffei, and Talaromyces stipitatus (P. stipitatum). (umd.edu)
  • Aspergillus fumigatus causes severe problems in poultry production systems. (up.ac.za)
  • The present study aims at the production optimization, purification, and characterization of a potent broad-spectrum antimicrobial compound (AMC) produced by Aspergillus fumigatus nHF-01 (GenBank Ac. (nature.com)
  • Aspergillus lentulus is a drug-resistant species that is phenotypically similar to A. fumigatus . (nih.gov)
  • Clinical labs can misidentify the species as fumigatus based on phenotypic typing. (nih.gov)
  • Excessive inflammation by phagocytes during Aspergillus fumigatus infection is thought to promote lung function decline in CF patients. (elsevierpure.com)
  • Aspergillus fumigatus and Aspergillus niger tolerate a wide range of temperatures (see the image below). (medscape.com)
  • Occurs when one species of Aspergillus, A. fumigatus, becomes resistant to certain medicines used to treat it. (cdc.gov)
  • In the present study, a total of 13, 12, 8 and 8 candidate fatty acid desaturases genes were identified in the Aspergillus oryzae , Aspergillus flavus , Aspergillus fumigatus and Aspergillus nidulans genomes through database searches, which were classified into five different subfamilies based on phylogenetic analysis. (springeropen.com)
  • Screening of cellulolytic activity by ten fungal isolates recovered from soil and agricultural wastes indicated that Aspergillus fumigatus showed the highest cellulolytic activity, under solid-state fermentation (SSF) using rice straw as substrate. (scialert.net)
  • Aspergillus fumigatus was isolated from 5 birds with characteristic lesions of airsacculitis. (cdc.gov)
  • The two fungal antigens ( Alternaria alternata and Aspergillus fumigatus ) measured are primarily outdoor antigens, which are transported into the indoor environment. (cdc.gov)
  • Aspergillus fumigatus is a common outdoor mold associated with decaying vegetative matter. (cdc.gov)
Flavus8
  • Aspergillus flavus , a species of fungus within Aspergillus section Flavi , can produce toxins that are harmful to mammals. (vanderbilt.edu)
  • E. Sánchez, N. Heredia and S. Garcia, "Inhibition of Growth and Mycotoxin Production of Aspergillus flavus and Aspergillus parasiticus by Extracts of Agave Species," International Journal of Food Microbiology, Vol. 98, No. 3, 2005, pp. 271-278. (scirp.org)
  • Aspergillus is a common human-pathogenic genus of fungi that includes A. flavus , which can cause aspergillosis and fungal keratitis infections, a type of eye infection. (vanderbilt.edu)
  • Hatmaker's work pushes the boundaries of our knowledge of the species complex beyond A. flavus , which is better studied in clinical settings than its sibling species. (vanderbilt.edu)
  • For A. flavus , I'm most interested in the evolution of pathogenicity and in diversity within the species," Hatmaker said. (vanderbilt.edu)
  • Aflatoxins are a family of compounds naturally produced by certain fungi, most often mold from the Aspergillus Flavus species. (msu.edu)
  • from the Aspergillus Flavus species ( 1 , 2 ). (msu.edu)
  • It's important to note that the presence of Aspergillus Flavus on a crop does not automatically mean that the crop's contaminated with aflatoxins. (msu.edu)
Penicillium3
  • In the current case study of 28 mold-infested buildings across the U.S. east coast, we surprisingly noted a trend of higher prevalence of indoor Aspergillus and Penicillium genera (denoted here as Asp-Pen) in buildings with previous flooding history. (nih.gov)
  • Despite the conservation of the core genes, the mitochondrial genomes of Aspergillus and Penicillium species examined here exhibit significant amount of interspecies variation. (umd.edu)
  • Several species of Aspergillus and Penicillium are known for solubilizing insoluble phosphates [ 2 - 4 ]. (hindawi.com)
Genus11
  • List of fungus species in the genus Aspergillus. (wikipedia.org)
  • The genus Aspergillus includes several hundred fungus species. (wikipedia.org)
  • Fungi of the genus Aspergillus are widespread in the environment. (jcvi.org)
  • With this first ever genus-wide view, the international consortium found that Aspergillus has a greater genomic and functional diversity than previously understood, broadening the range of potential applications for the fungi considered one of the most important workhorses in the biotechnology. (sciencedaily.com)
  • Other species in this genus play critical roles in biofuel production, and plant and human health. (sciencedaily.com)
  • However, little is known about the diversity in the species at the genomic level and this paper demonstrates how diverse the species of this genus are," said study lead author Ronald de Vries of the Westerdijk Fungal Biodiversity Institute in the Netherlands. (sciencedaily.com)
  • One can't assume that an Aspergillus species will have the same physiology as a better studied species of the genus. (sciencedaily.com)
  • Furthermore, genus-specific probes are also provided for Aspergillus, Fusarium and Mucor, in addition to an all-fungus nucleic acid probe. (epo.org)
  • From an undisturbed natural forest soil in Ecuador, three fungal strains of the genus Aspergillus were isolated. (ups.edu.ec)
  • The study focused on the mitochondrial genomes of 20 different Aspergillus species, a type of fungi, to examine the relationships within section Flavi , a group of closely related species within the genus Aspergillus . (vanderbilt.edu)
  • The genus Aspergillus is incredibly diverse in a multitude of traits, so it ultimately would benefit the scientific community to have the genomes of species causing each infection available for further study. (vanderbilt.edu)
Genomes8
  • All of the sequenced genomes have a group I intron in the large ribosomal subunit RNA gene, suggesting that this intron is fixed in these species. (umd.edu)
  • The sequencing the genomes of 10 novel Aspergillus species, which were compared with the eight other sequenced Aspergillus species, has now been announced by researchers. (sciencedaily.com)
  • In a study published February 14, 2017 in the journal Genome Biology , an international team including researchers at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, report sequencing the genomes of 10 novel Aspergillus species, more than doubling the number of Aspergillus species sequenced to date. (sciencedaily.com)
  • The newly sequenced genomes were compared with the eight other sequenced Aspergillus species. (sciencedaily.com)
  • Sequencing a diverse set of Aspergillus genomes allows researchers to build a more comprehensive catalog of enzymes for biotechnological applications, added DOE JGI Fungal Genomics Program Head Igor Grigoriev, senior author of the paper. (sciencedaily.com)
  • Comparing the newly sequenced genomes to those already available, researchers found a huge variety of carbohydrate-active enzymes (CAZymes) among the Aspergillus species, suggesting distinct strategies to break down plant biomass. (sciencedaily.com)
  • VU alumni Miya Hugaboom studied the nuclear and mitochondrial genomes of 20 different Aspergillus species within section Flavi . (vanderbilt.edu)
  • If every clinical laboratory had money and equipment to sequence the genomes of all their fungal strains isolated from patients, we would see a lot finer resolution in which species are regularly infecting humans and more diversity in rare infections," Hatmaker said. (vanderbilt.edu)
Nidulans2
Fungus3
  • Seven South African tree species were selected from the database of the Phytomedicine Programme based on its antifungal activity against the fungus Cryptococcus neoformans. (up.ac.za)
  • Aspergillosis is a disease caused by Aspergillus , a common mold (a type of fungus) that lives indoors and outdoors. (cdc.gov)
  • Aspergillus species is a fungus that often lives in the airways of children and adults with cystic fibrosis. (cff.org)
Niger4
  • Aspergillus niger , for example, has been used for decades to produce citric acid -- a compound frequently added to foods and pharmaceuticals -- through fermentation at an industrial scale. (sciencedaily.com)
  • Three species of Aspergillus , namely, A. niger , A. glaucus and A. sydowii , isolated from soil samples collected from the Indian Himalayan Region (IHR), have been investigated for solubilization of aluminium phosphate and iron phosphate in the presence of different carbon and nitrogen sources. (hindawi.com)
  • In a recent study, tricalcium phosphate solubilization efficiency of ten cold- and pH-tolerant species of Aspergillus have been reported, with A. niger followed by A. glaucus and A. sydowii , respectively, being the best performers [ 15 ]. (hindawi.com)
  • The most frequent species were Candida albicans, Aspergillus niger, Cladosporium cladosporioides and Cladosporium oxysporum. (bvsalud.org)
Isolates5
Candida1
Oryzae1
  • Wine-lovers generally associate alcoholic drink-making in Japan with yellow koji mold ( Aspergillus oryzae ) converting rice starch to sugars and fermenting cereal beverages. (wizzley.com)
Genes1
  • Furthermore, a comprehensive analysis was performed to characterize conserved motifs and gene structures, which could provide an intuitive comprehension to learn the relationship between structure and functions of the fatty acid desaturases genes in different Aspergillus species. (springeropen.com)
Rhizopus1
  • Unique internal transcribed spacer 2 coding regions permit the development of nucleic acid probes specific for five different species of Aspergillus, three species of Fusarium, four species of Mucor, two species of Penecillium, five species of Rhizopus, one species of Rhizomucor, as well as probes for Absidia corymbifera, Cunninghamella elagans, Pseudallescheria boydii, and Sporothrix schenkii. (epo.org)
Strains3
  • Three strains of the Aspergillus versicolor complex were isolated from a salty marsh at a former uranium mining site in Thuringia, Germany. (leibniz-hki.de)
  • This study provided a better understanding of the evolution and functions of the fatty acid desaturases gene family in the four Aspergillus species, and would be useful for seeking methods to improve the production of unsaturated fatty acids and enhance efforts for the genetic improvement of strains to adapt to the complex surrounding environment. (springeropen.com)
  • In fact, when fungal keratitis is diagnosed in a medical lab, the conclusion is often just Aspergillus , which can be useful for medical doctors but leave something to be desired for researchers seeking to have a better understanding of the evolution of Aspergillus and how it might be treated, or even predict which strains may become pathogenic in the future. (vanderbilt.edu)
Aflatoxin production3
  • In order to study the relationship between the distribution and aflatoxin production capacity of Aspergillus species and soil types, 35 soil samples were collected from the main peanut planting areas in Xiangyang, which has 19.7 thousand square kilometers and is located in a special area with different soil types. (mdpi.com)
  • Therefore, assessment of the response of aflatoxigenic species to different temperatures is important to add information about the understanding of aflatoxin production by Aspergillus nomius and may help in the development of new strategies to prevent aflatoxin contamination. (researchgate.net)
  • F. Olojede, G. Engelhardt, P. R. Wallnofer and G. O. Adegoke, "Decrease of Growth and Aflatoxin Production in Aspergillus parasiticus Caused by Spices," WJ Microbiology and Biotechnology, Vol. 9, No. 5, 1995, pp. 605-606. (scirp.org)
Infection7
  • Contamination with mycotoxins is a recurrent problem in Brazil nuts and is caused mainly by post-harvest infection with Aspergillus section Flavi species. (researchgate.net)
  • Occurs when Aspergillus causes inflammation in the lungs and allergy symptoms such as coughing and wheezing, but doesn't cause an infection. (cdc.gov)
  • Occurs when Aspergillus causes inflammation in the sinuses and symptoms of a sinus infection (drainage, stuffiness, headache) but doesn't cause an infection. (cdc.gov)
  • Occurs when Aspergillus infection causes cavities in the lungs, and can be a long-term (3 months or more) condition. (cdc.gov)
  • Occurs when Aspergillus causes a serious infection, and usually affects people who have weakened immune systems, such as people who have had an organ transplant or a stem cell transplant. (cdc.gov)
  • Occurs when Aspergillus enters the body through a break in the skin (for example, after surgery or a burn wound) and causes infection, usually in people who have weakened immune systems. (cdc.gov)
  • A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart. (medscape.com)
Mold2
Aspergillosis1
Fungi species1
  • One important trait of these fungi species is the interaction between environment and pathogenicity. (vanderbilt.edu)
Alternaria1
  • Alternaria alternata is a species of cosmopolitan dematiaceous fungi commonly isolated from plants, soil, and food. (cdc.gov)
Versicolor2
  • Salt and metal tolerance involves formation of guttation droplets in species of the Aspergillus versicolor complex. (leibniz-hki.de)
  • Harpke M, Pietschmann S, Ueberschaar N, Krüger T, Kniemeyer O, Brakhage AA, Nietzsche S, Kothe E (2022) Salt and metal tolerance involves formation of guttation droplets in species of the Aspergillus versicolor complex. (leibniz-hki.de)
Kwon-Chung1
Cystic fibrosis1
  • Some of these species pose serious risks to the health of a person with cystic fibrosis. (cff.org)
Microbiology1
  • C. Tzanidi, C. Proestos and P. Markaki, "Saffron ( Crocus sativus L. ) Inhibits Aflatoxin B 1 Production by Aspergillus parasiticus ," Advances in Microbiology , Vol. 2 No. 3, 2012, pp. 310-316. (scirp.org)
Conidial1
  • Aspergillus iranicus (CBS 139561T) is phylogenetically related to A. carneus, A. niveus, A. allahabadii and A. neoindicus, and it can be differentiated from those species by a unique extrolite pattern (citrinin, gregatins, and a terrequinone) and its conidial colour. (knaw.nl)
Spores1
Aflatoxins2
  • Aspergillus nomius is a potent producer of aflatoxins B and G and is one of the most common species of fungi found in Brazil nuts. (researchgate.net)
  • It can infect plants, it can produce some of the most famous toxins produced by fungi (aflatoxins), and it can directly infect humans-what an incredible range for one species. (vanderbilt.edu)
Amazonicus2
Organisms2
  • Patients at risk should be counseled to avoid exposure to Aspergillus organisms. (medscape.com)
  • various species of organisms from the It is important to ascertain the cause surface burn wounds were roughly pro- of the burn because this may be helpful portional to those from blood specimens or in determining burn depth. (who.int)
Pathogens2
  • Here, we synthesize these findings in relation to the way in which some Aspergillus species have become successful opportunistic pathogens of human- and other animal hosts. (jcvi.org)
  • We focus on the biophysical capabilities of Aspergillus pathogens, key aspects of their ecophysiology and the flexibility to undergo a sexual cycle or form cryptic species. (jcvi.org)
Pulmonary1
  • Erosion of a major pulmonary artery caused by angiotropism of the Aspergillus species may lead to severe hemorrhage. (medscape.com)
Horie3
Taxonomic1
  • JASPAR is an open-access database of curated, non-redundant transcription factor (TF) binding profiles stored as position frequency matrices (PFMs) and TF flexible models (TFFMs) for TFs across multiple species in six taxonomic groups. (genereg.net)
Reactive1
  • Pathogen restriction is enhanced by the nutrient-limiting ability of the phagolysosome and the input of antimicrobial agents into the lumen, such as reactive oxygen/nitrogen species (ROS/RNS) ( 10 ). (frontiersin.org)
Carcinogenic1
  • Aflatoxin B 1 (AFB 1 ) is a carcinogenic metabolite produced by certain Aspergillus species. (scirp.org)
Advantageous1
  • Hatmaker and the team found that secondary metabolites-compounds produced that are not necessary for survival but can be advantageous in specific environments-differed among species at room temperature. (vanderbilt.edu)
Significantly1
  • Significantly higher indoor concentrations of fungal species, including Aspergillus spp. (cdc.gov)
Extracts1
  • The acetone leaf extracts of the selected species hadminimum inhibitory concentrations (MICs) of 0.16 mg/ml and lower in the preliminary screening. (up.ac.za)
Inflammation2
  • Other treatments including azithromycin and acebilustat may dampen Aspergillus-induced inflammation due to their immunomodulatory properties. (elsevierpure.com)
  • In summary, CFTR modulators have potential for additional immunomodulatory benefits to prevent or treat Aspergillus-induced inflammation in CF. The comparable effects of CFTR modulators observed in phagocytes from control subjects questions their exact mechanism of action. (elsevierpure.com)
Antimicrobial1
  • medical care, distribution of species responsible and prevalence of antimicrobial resistance [4,5]. (researchgate.net)
Different species1
  • The Burkholderia cepacia complex ( B. cepacia ) consists of different species of bacteria that are found in the natural environment. (cff.org)
Severe1
  • This procedure is superior after hospital discharge, 54% of patients to the swab culture in identifying different showed symptoms of moderate to severe bacterial species. (who.int)
Invasive1
  • A isolate, patient characteristics were registered through an zole resistance is increasingly recognized as a prob- online questionnaire, and patients with invasive aspergillo- lem in aspergillus diseases ( 1 ). (cdc.gov)
Clinical1
  • To investigate azole resistance in clinical Aspergillus iso- lance Collaboration on Aspergillus Resistance in Europe lates, we conducted prospective multicenter international [SCARE-network]), comprising 22 centers from 19 coun- surveillance. (cdc.gov)
ERMI3
  • The ERMI scores were driven by the high concentrations of Group 1 species with a mean of 15.8 and an IQR of 13. (cdc.gov)
  • There were 63 additional species identified in the culturable air samples not included in the ERMI. (cdc.gov)
  • ERMI did not identify all relevant fungal species associated with this specific occupational environment. (cdc.gov)
Indoor1
  • The indoor/outdoor ratio of geometric means across all 36 species per IMGO ranged from 0.4 to 6.2. (cdc.gov)
Bacterial species1
  • Fungal species, in this context, have been recognized as more appropriate compared to bacterial species [ 14 ]. (hindawi.com)
Study3
  • There is [still] much to learn and get from a better study [of Aspergillus ]," he said. (sciencedaily.com)
  • In the present study, response of these three cold-tolerant Aspergillus spp. (hindawi.com)
  • Annie Hatmaker, along with a team of researchers including her adviser, Cornelius Vanderbilt Professor of Biological Sciences Antonis Rokas, recently published a study identifying the differences in virulence among Aspergillus species. (vanderbilt.edu)
Infections1
  • AmBisome) in order to determine its maximally tolerated dosage (MTD) in patients with infections due to Aspergillus spp. (johnshopkins.edu)