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Aspartate AminotransferasesAlanine TransaminaseTransaminasesLiverAlanineTyrosine TransaminaseDrug-Induced Liver InjuryAspartate Aminotransferase, MitochondrialPyridoxal PhosphateLiver Function Testsgamma-GlutamyltransferaseOrnithine-Oxo-Acid TransaminasePyridoxamineLiver DiseasesAspartic AcidBilirubin4-Aminobutyrate TransaminaseAspartate CarbamoyltransferaseCarbon TetrachlorideL-Lactate DehydrogenaseFatty LiverLiver CirrhosisGalactosamineClinical Enzyme TestsAspartate Aminotransferase, CytoplasmicBlood Chemical AnalysisPyridoxalAcetaminophenD-Alanine TransaminaseKetoglutaric AcidsAlkaline PhosphataseHepatitis B, ChronicVitamin B 6 DeficiencyBiological MarkersKineticsAminooxyacetic AcidCarbon Tetrachloride PoisoningHepatitis C, ChronicProtective AgentsReperfusion InjuryCreatine KinaseMitochondria, LiverMolecular Sequence DataPyridoxineIsoenzymesOxamic AcidHepatitis CAmino Acid SequenceAspartate Ammonia-LyaseHepatitis B e AntigensRats, WistarChemistry, ClinicalGlutamatesAmino AcidsHepatitisGlutamate DehydrogenaseApoenzymesNecrosisCytosolAlanine RacemaseSwineHepatitis, Viral, HumanHepatocytesTime FactorsPlant ExtractsEscherichia coliEnzymesLiver TransplantationSubstrate SpecificityMalondialdehydeAutoanalysisAnalgesics, Non-NarcoticMalate DehydrogenaseAntiviral AgentsCholagogues and CholereticsGlyoxylatesHepatitis B virusRecombinant ProteinsLiver Failure, AcuteCholestasisAminobutyratesHepacivirusLiver Cirrhosis, ExperimentalRats, Sprague-DawleyLiver CirculationLiver Diseases, AlcoholicSpectrophotometryGlutamineMitochondriaBinding SitesInterferon-alphaHepatitis BDisease Models, AnimalBase SequenceDrugs, Chinese HerbalProtein ConformationHyperoxaluria, PrimarySchiff BasesCycloserineGlycine Transaminase
TransaminaseLiverCreatine kinaseSGOTBilirubinElevationRatioElevationsEnzymesLevelsSignificantlySerumAlkalineCreatine KinaseGlucosePlasmaParametersDiet
Transaminase5
  • Another name for aminotransferase is transaminase. (medicinenet.com)
  • The enzyme aspartate aminotransferase (AST) is also known as serum glutamic oxaloacetic transaminase (SGOT). (medicinenet.com)
  • Alanine aminotransferase (ALT) is also known as serum glutamic pyruvic transaminase (SGPT). (medicinenet.com)
  • Activities of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP) and plasma concentrations of total and conjugated bilirubin, total protein and albumin were determined using standard methods. (karger.com)
  • Aspartate transaminase catalyzes the interconversion of aspartate and α-ketoglutarate to glutamate. (medscape.com)
Liver7
  • Although often used to detect liver disease, the prevalence and etiology of elevated aminotransferases are unknown. (nih.gov)
  • Unexplained aminotransferase elevation was strongly associated with adiposity and other features of the metabolic syndrome, and thus may represent nonalcoholic fatty liver disease. (nih.gov)
  • Among the most sensitive and widely used liver enzymes are aminotransferases. (medicinenet.com)
  • The ratio of aspartate aminotransferase to alanine aminotransferase: potential value in differentiating nonalcoholic steatohepatitis from alcoholic liver disease. (kcl.ac.uk)
  • Because aminotransferases and alkaline phosphatase are included in commonly done laboratory test panels, abnormalities are often detected in patients without symptoms or signs of liver disease. (msdmanuals.com)
  • Many investigators have reported that interferon-based treatment is effective in reducing serum alanine aminotransferase (ALT) levels, eradicating HCV RNA and reducing liver fibrosis in patients with chronic HCV infection. (medscape.com)
  • Another enzyme, alanine aminotransferase or ALT, is primarily found in the liver. (medscape.com)
Creatine kinase1
SGOT2
Bilirubin2
  • alanine aminotransferas) with mild increase of total bilirubin levels (Anicteric hepatitis). (wjgnet.com)
  • Monitor platelet count, serum creatinine, estimated glomerular filtration rate (eGFR), urinalysis, urine protein to creatinine ratio (UPCR), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and total bilirubin during treatment with TEGSEDI, and for 8 weeks following discontinuation of treatment. (drugs.com)
Elevation2
  • Aminotransferase elevation was classified as "explained" if there was laboratory evidence of hepatitis B or C infection, iron overload, or if there was a history of alcohol consumption. (nih.gov)
  • Aminotransferase elevation was common in the United States, and the majority could not be unexplained by alcohol consumption, viral hepatitis or hemochromatosis. (nih.gov)
Ratio1
  • Objectives: The objectives of the current study were to associate novel markers, including aspartate aminotransferase-to-platelet ratio (APRI) and aspartate aminotransferase-to-alanine aminotransferase ratio (AAR) with survival in esophageal malignancy. (aku.edu)
Elevations1
  • Complications included hyperglycemia and elevations in alanine aminotransferase and aspartate aminotransferase. (medpagetoday.com)
Enzymes2
  • What are the aminotransferase enzymes (ALT, AST)? (medicinenet.com)
  • The aminotransferase enzymes catalyze chemical reactions in which an amino group from one amino acid (amino acids are building blocks of proteins) is transferred from a donor molecule to a recipient molecule, hence, the name 'aminotransferases. (medicinenet.com)
Levels3
  • Participants were classified as having elevated aminotransferase levels if either aspartate aminotransferase or alanine aminotransferase was elevated above normal. (nih.gov)
  • Levels of plasma alanine aminotransferase and aspartate aminotransferase were not significantly altered by the treatment. (cdc.gov)
  • Results Alanine aminotransferase and homeostatic model assessment-insulin resistance levels decreased significantly from baseline to SVR24. (medscape.com)
Significantly1
  • Plasma alanine aminotransferase (ALT), measured at 24-hour intervals from 24-96 hours after dosing and evaluated as the area under the curve (AUC), was significantly lower in the mixture groups than predicted by the sum of measured responses to each chemical alone, indicating a less-than-effect-additive joint toxic action. (cdc.gov)
Serum6
  • Risk prediction following acetaminophen (paracetamol, APAP) overdose is based on serum APAP, aspartate aminotransferase (AST), and alanine aminotransferase (ALT) levels. (nih.gov)
  • To describe the changes in serum alanine aminotransferase (ALT) levels in nondrinkers receiving acetaminophen for 10 days. (medscape.com)
  • Studies have shown that administration of the maximum recommended dose (4 g/day) of acetaminophen for more than 3 consecutive days caused elevations of serum alanine aminotransferase (ALT) levels in some subjects, both those who consumed and did not consume alcohol. (medscape.com)
  • Having this background, the present study was designed to investigate the correlation between the levels of serum liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST) and GGT and Asia-Pacific cut-off points of BMI in healthy individuals. (springeropen.com)
  • TMF-treated rats showed significantly lower relative enhancement (RE) values and serum alanine aminotransferase (ALT) and aspartate aminotransferase levels than did untreated rats at three hours after reperfusion. (researchsquare.com)
  • In contrast, B. subtilis reduced serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), malondialdehyde (MDA) and C3 complement ( P (ejbiotechnology.info)
Alkaline1
Creatine Kinase1
Glucose1
  • The most common laboratory abnormalities (≥15%) were increased glucose, triglycerides, alanine aminotransferase, and aspartate aminotransferase. (fda.gov)
Plasma1
  • Plasma alanine aminotransferase (ALT), measured at 24-hour intervals from 24-96 hours after dosing and evaluated as the area under the curve (AUC), was significantly lower in the mixture groups than predicted by the sum of measured responses to each chemical alone, indicating a less-than-effect-additive joint toxic action. (cdc.gov)
Parameters1
  • Laboratory parameters (alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), creatinine) did not indicate organ rejection at any stage of the experiment. (nih.gov)
Diet1
  • This research is being done to determine if men with rising PSA after initial therapy for localized prostate cancer who display the Alanine/Alanine SOD2 genotype of MnSOD and supplement their diet with MPX have greater decrease in PSA slope following treatment compared to men that do not supplement with MPX. (dana-farber.org)