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Acid Sensing Ion ChannelsDegenerin Sodium ChannelsSodium ChannelsNerve Tissue ProteinsSpider VenomsAcid Sensing Ion Channel BlockersEpithelial Sodium ChannelsAcidsHydrogen-Ion ConcentrationCnidarian VenomsMembrane ProteinsProtonsAcidosisAmilorideGanglia, SpinalFMRFamideSodium Channel AgonistsSodium Channel BlockersXenopus laevisCricetulusSensory Receptor CellsPatch-Clamp TechniquesAmmonium CompoundsCHO CellsIon Channel GatingEpithelial Sodium Channel BlockersNeuronsMyositisNociceptorsNociceptionNeurons, AfferentCricetinaeExtracellular FluidElectrophysiologyProtein Structure, TertiaryMechanotransduction, CellularIon ChannelsHyperalgesiaOocytesMice, KnockoutMechanoreceptorsTRPV Cation ChannelsCOS CellsProtein SubunitsPainGanglia, SensorySea AnemonesCarrageenanReducing AgentsHSC70 Heat-Shock ProteinsHippocampusXenopusCalciumMice, Inbred C57BLCells, CulturedPhysiological ProcessesMembrane PotentialsNodose GanglionCapsaicinThymus PlantAgmatineProtein IsoformsRats, Sprague-DawleyNasal SeptumTransfectionIonsBehavior, AnimalMusculoskeletal PainPeptidesBiotinylationMutagenesis, Site-DirectedCercopithecus aethiopsPhysical StimulationProto-Oncogene Proteins c-sisNaphthalenesFlurbiprofenPain ThresholdElectrophysiological PhenomenaAmino Acid SequenceAcid-Base ImbalanceTaste BudsIodoacetic AcidMuscle, SkeletalFootLactic AcidIsoquinolinesMolecular Sequence DataGuanidinesGuanylate KinaseTachyphylaxisLampreysDextromethorphanDendritic SpinesAmino Acid Transport System y+NeuralgiaReverse Transcriptase Polymerase Chain ReactionLipoylationZincProtein BindingGadolinium
ASIC3Asic2Gene
ASIC32
  • 18. ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration. (nih.gov)
  • May regulate ASIC1/ASIC3 channel. (nih.gov)
Asic22
  • Differential gene profiling data showed that ASIC1 and ASIC2 mRNA were present in normal and low grade tumor cells. (archive.org)
  • Our results show that 1) gain-of-function mutations of ASIC1 were not present in a number of freshly resected and cultured high grade gliomas, 2) syntaxin 1A inhibited ASIC currents only when ASIC1 and ASIC2 were co-expressed, and 3) the inhibition of ASIC currents by syntaxin 1A had an absolute requirement for either ␥or ␦-hENaC. (archive.org)
Gene2
  • Acid-sensing ion channel 1 (ASIC1) also known as amiloride-sensitive cation channel 2, neuronal (ACCN2) or brain sodium channel 2 (BNaC2) is a protein that in humans is encoded by the ASIC1 gene. (wikipedia.org)
  • The ASIC1 gene is one of the five paralogous genes that encode proteins that form trimeric acid-sensing ion channels (ASICs) in mammals. (wikipedia.org)