• Neutral ceramidase is an enzyme that in humans is encoded by the ASAH2 gene. (wikipedia.org)
  • Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids. (musc.edu)
  • This approach enabled us to nominate the gene encoding the neutral ceramidase, Asah2, as a novel candidate driver at a QTL on chromosome 19 for large HDL particles (HDL-2b). (bvsalud.org)
  • Human ASAH2 genome location and ASAH2 gene details page in the UCSC Genome Browser. (wikipedia.org)
  • To experimentally validate Asah2, we surveyed lipoproteins in Asah2-/- mice. (bvsalud.org)
  • Compared to wild-type mice, female Asah2-/- mice showed an increase in several lipoproteins, including HDL. (bvsalud.org)