What are Alkyl halides and Aryl halides? (bartleby.com)
Metals react with aryl halides and alkyl halides and they also go through nucleophilic substitution reactions and elimination reactions. (bartleby.com)
A general palladium-catalyzed reaction using the CyPF- t -Bu ligand for the coupling of aryl halides and sulfonates with thiols exhibits extraordinary turnover numbers and high tolerance of functional groups. (organic-chemistry.org)
The well-defined palladium N -heterocyclic carbene (NHC) complex [Pd(IPr* OMe )(cin)(Cl)] provides high catalytic activity for carbon-sulfur cross-coupling reactions of nonactivated and deactivated aryl halides with a large variety of aryl- and alkylthiols. (organic-chemistry.org)
A nickel-catalyzed C-S reductive cross-coupling of alkyl halides with arylthiosilanes provides alkyl aryl thioethers. (organic-chemistry.org)
A mild, scalable, visible-light-promoted cross-coupling reaction between thiols and aryl halides provides various aryl thioethers in the absence of both transition metal and photoredox catalysts. (organic-chemistry.org)
An operationally simple mechanochemical C-S coupling of aryl halides with thiols operates under benchtop conditions without the requirement for a (dry) solvent, an inert atmosphere, or catalyst preactivation. (organic-chemistry.org)
A versatile and efficient Pd(OAc) 2 /1,1'-bis(diisopropylphosphino)ferrocene-catalyzed cross-coupling of thiols with aryl halides was developed. (organic-chemistry.org)
The oxidative addition of aryl halides is a common entry point in catalytic cycles for cross-coupling and related reactions. (uu.nl)
Copper catalysts promote the coupling of a wide range of nitrogen nucleophiles, including amines, amides, and heteroaromatic nitrogen compounds with aryl and alkenyl halides. (stanford.edu)
Optimal experimental conditions for the amination of aryl and alkenyl halides with all classes of nitrogen nucleophiles are presented. (stanford.edu)
Iodides8
Takuya Kurahashi, Seijiro Matsubara, and colleagues, Kyoto University, Japan, have developed an intermolecular, nickel-catalyzed reaction of alkynes with aryliodides that gives alkenyl iodides (pictured). (chemistryviews.org)
The team used a range of aryliodides and substituted alkynes as substrates, Ni(cod) 2 as a catalyst (cod = 1,5-cyclooctadiene), 4,4′-di- tert -butyl-2,2′-dipyridyl (dtbdp) as a ligand, and toluene as solvent. (chemistryviews.org)
A copper-catalyzed coupling of aryliodides with dimethyl disulfide in water enables an efficient route to aryl methyl sulfides in good yields. (organic-chemistry.org)
Highly chemoselective C-S cross-couplings of aryl, benzyl, and alkyl thiols with aryl and heteroaryl iodides were achieved versus competitive C-O and C-N cross-couplings in the presence of an Ir-photoredox catalyst. (organic-chemistry.org)
Regioselective zincation of indazoles using TMP2Zn and Negishi cross-coupling with aryl and heteroaryl iodides. (uni-muenchen.de)
Palladium-catalyzed ring expansion reaction of (Z)-1-(1,3-butadienyl)cyclobutanols with aryliodides. (unboundmedicine.com)
reaction: see text] A novel type of cascade ring expansion process has been developed by the palladium-catalyzed reaction of (Z)-1-(1,3-butadienyl)cyclobutanols with aryliodides. (unboundmedicine.com)
AU - Yoshida,Masahiro, AU - Sugimoto,Kenji, AU - Ihara,Masataka, PY - 2004/6/5/pubmed PY - 2005/4/2/medline PY - 2004/6/5/entrez SP - 1979 EP - 82 JF - Organic letters JO - Org Lett VL - 6 IS - 12 N2 - [reaction: see text] A novel type of cascade ring expansion process has been developed by the palladium-catalyzed reaction of (Z)-1-(1,3-butadienyl)cyclobutanols with aryliodides. (unboundmedicine.com)
Receptors2
AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish. (oregonstate.edu)
Aryl hydrocarbon receptors improve migraine-like pain behaviors in rats through the regulation of regulatory T cell/T-helper 17 cell-related homeostasis. (medscape.com)
Hydrocarbon receptor agonists1
Aryl Hydrocarbon Receptor Agonists " has 5 results in Products. (rndsystems.com)
Abstract1
abstract = "We hypothesized that an interplay between aryl hydrocarbon receptor (AhR) and cysteine-related thiolome at the kidney cortex underlies the mechanisms of (mal)adaptation to chronic intermittent hypoxia (CIH), promoting arterial hypertension (HTN). (unl.pt)
Oxidative1
The proposed mechanism involves the oxidative addition of the aryl iodide to the nickel complex, followed by the homolysis of the resulting unstable Ni-C bond, which generates a radical. (chemistryviews.org)
Synthesis2
Herein we report the design, synthesis, and utilization of two novel aryl amphiphiles as shape-directors (ShaDs) to obtain particles of different shape. (rsc.org)
The metal-catalyzed amination of aryl and alkenyl electrophiles has developed into a widely used methodology for the synthesis of natural products, active pharmaceutical ingredients, agricultural chemicals, and materials for molecular electronics. (stanford.edu)
Reactions4
Lutz Ackermann describes new cobalt-catalyzed aryl C-H activation reactions. (thieme.de)
For subsequent reactions, I would like to cleave the aryl methyl ether group to obtain a phenol. (chemicalforums.com)
All reactions are generally tolerant towards different aryl substitutions, substitution patterns, alkyl chain lengths and can be carried out in a multigram scale [57] . (beilstein-journals.org)
The reactions were applicable to five-membered and six-membered heteroaryl arylethers and also to diaryl ethers possessing one or two electron-withdrawing groups. (elsevierpure.com)
Alkenyl1
Copper-Catalyzed Amination of Aryl and Alkenyl Electrophiles is intended to provide organic chemists with an accessible, but detailed, introduction to this important class of transformations. (stanford.edu)
A rhodium complex catalyzed the conversion of the C-O bond of heteroaryl arylethers to the C-F bond. (elsevierpure.com)
The reaction of heteroaryl arylethers with 2-fluorobenzothiazole in which two heteroaryl and aryl C-O bonds were cleaved provided heteroaryl fluorides and aryl fluorides. (elsevierpure.com)
Ketones2
A cycloisomerization of aryl allenyl ketones to 3-arylidene-indan-1-ones using a cationic Fe-complex as a catalyst is reported. (acs.org)
Iron(III)-Mediated Bicyclization of 1,2-Allenyl Aryl Ketones: Assembly of Indanone-Fused Polycyclic Scaffolds and Dibenzo[a,e]pentalene Derivatives. (acs.org)
Ligands1
The lung undergoes substantial growth, alveolarization, and cellular maturation within the first years of life, which may be impacted by environmental pollutants such as PM. PAHs in PM can serve as ligands for the aryl hydrocarbon receptor (AhR) that induces expression of certain isozymes in the cytochrome P-450 superfamily, such as CYP1A1 and CYP1B1, localized in specific lung cell types. (cdc.gov)
Stereospecific2
"Rat brain aryl acylamidase: stereospecific inhibition by LSD and serotonin-related compounds" J. Neurochem. . (erowid.org)
The reaction proceeds in a stereospecific manner to produce (Z)-2-(3-aryl-1-propenyl)cyclopentanones. (unboundmedicine.com)
Reaction2
In enzymology, an aryl-acylamidase (EC 3.5.1.13) is an enzyme that catalyzes the chemical reaction an anilide + H2O ⇌ {\displaystyle \rightleftharpoons } a carboxylate + aniline Thus, the two substrates of this enzyme are anilide and H2O, whereas its two products are carboxylate and aniline. (wikipedia.org)
Air-stable defined Ni precatalysts enable a general and efficient coupling of challenging aryl chlorides and in situ generated aliphatic and aromatic thiolates at unprecedented moderate catalyst loadings and reaction temperatures. (organic-chemistry.org)
Alkynes2
A Rh-catalyzed annulation of aryl thiocarbamates with internal alkynes via C-H bond activation has been developed. (unboundmedicine.com)
AU - Zhao,Yingwei, AU - Han,Feng, AU - Yang,Lei, AU - Xia,Chungu, Y1 - 2015/03/11/ PY - 2015/3/12/entrez PY - 2015/3/12/pubmed PY - 2015/8/22/medline SP - 1477 EP - 80 JF - Organic letters JO - Org Lett VL - 17 IS - 6 N2 - A Rh-catalyzed annulation of aryl thiocarbamates with internal alkynes via C-H bond activation has been developed. (unboundmedicine.com)
Aromatic3
An aryl halide is formed when an atom of hydrogen is substituted by a halogen atom in an aromatic compound. (bartleby.com)
Aryl bromides and chlorides can be coupled to aliphatic and aromatic thiols - the widest substrate scope of any reported to date. (organic-chemistry.org)
In the present work, we have functionalized isosorbide 5-methacrylate with various aromatic lignin-inspired esters to yield a series of isosorbide-2-aryl carboxylate-5-methacrylate monomers (ArIMAs) as single regioisomers. (lu.se)
Compounds1
Organic compounds having two alkyl or aryl groups bonded to an oxygen atom, as in the formula R1-O-R2. (bvsalud.org)
Transcription3
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that integrates environmental, dietary, microbial and metabolic cues to control complex transcriptional programmes in a ligand-specific, cell-type-specific and context-specific manner. (nih.gov)
The aryl hydrocarbon receptor (AhR) transcription factor is increasingly recognized as functioning in cell cycle control. (aspetjournals.org)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and a member of the basic helix-loop-helix PER/ARNT/SIM family of chemosensors and developmental regulators. (oregonstate.edu)
Derivatives2
Our results demonstrate that the inhibition of rat brain aryl acylamidase occurs only in the presence of phar macologically active tryptamine derivatives, is stereospeci tic with respect to its inhibition by lysergic acid diethyl amide (LSD), and thus might provide a basis for studying LSD serotonin-receptor interaction in vitro. (erowid.org)
An iron(III) chloride hexahydrate-catalyzed Friedel-Crafts acylation of benzene derivatives in tunable aryl alkyl ionic liquids (TAAILs) has been developed. (beilstein-journals.org)
Enzyme1
The systematic name of this enzyme class is aryl-acylamide amidohydrolase. (wikipedia.org)
Differentiation1
The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. (umassmed.edu)
Catalytic1
In this contribution, we present the use of imidazolium-based tunable aryl alkyl ionic liquids (TAAILs) in a catalytic Friedel-Crafts acylation. (beilstein-journals.org)
Activation1
Figure 1 Illustration demonstrating a hypothetical summary of the potential effect of aryl-hydrocarbon receptor activation on multipotent mesenchymal stromal cell function. (wjgnet.com)
Formation1
In the case of phosphine-supported nickel(0) fragments, the formation of reactive Ni(ii)-aryl products often competes with the production of Ni(i) species. (uu.nl)
Involves1
A convenient method for C-S cross-coupling of arylbromides with various thiols involves the use of a 1,1′-bis(diphenylphosphino)ferrocene (DPPF)-ligated palladium complex with N,N -diisopropylethylamine (DIPEA) as the base. (organic-chemistry.org)
Atom1
This thioetherification of various aryl and heteroaryl bromides with a diverse array of thiols tolerates a wide range of functional groups due to the S-H selective H atom abstraction event. (organic-chemistry.org)
High1
Polymerizations were carried out by conventional free radical initiation to obtain the corresponding high molecular-weight poly(aryl carboxylate isosorbide methacrylate)s (PArIMAs). (lu.se)
Study2
Molecular docking study revealed the binding orientations of aryl hydrazines and hydrazides analogues in the active sites of thymidylate synthase. (amrita.edu)
In this study, Aryl hydrocarbon receptor (AhR) expression was associated with lymph node and distant metastasis in patients with gastric cancer and was correlated with clinicolpathological pattern. (oncotarget.com)
Studies2
Aryl hydrazine and hydrazide analogues were synthesized based on p-tolyl hydrazine, isolated as a breakdown product of a secondary metabolite from the mushroom, Agaricus bisporus, and tested to be highly active molecule than 5-fluorouracil in in vitro anticancer studies. (amrita.edu)
Circular dichroism studies of aryl diastereoisomers. (bvsalud.org)
Environmental1
The aryl hydrocarbon receptor (AHR) mediates the toxic actions of environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo- ρ -dioxin (TCDD), and also plays roles in vascular development, the immune response, and cell cycle regulation. (diagenode.com)