• Mar. 16, 2022 Biological processes such as wound healing and cancer cell invasion rely on the collective and coordinated motion of living cells. (sciencedaily.com)
  • Thermal transfer plays an important role in many biological processes. (edu.au)
  • Researchers in this field unravel the molecular and physiological mechanisms of life, develop increasingly advanced technologies to transform healthcare, and reverse-engineer naturally occurring biological processes. (mcgill.ca)
  • in Biological and Biomedical Engineering Non-Thesis program focuses on the life sciences, the physical sciences, and engineering, industrial practices and processes, and data science related to areas such as biological products, biomedical devices, and medical imaging. (mcgill.ca)
  • Schilstra, M. J., Martin, S. R. and Keating, S. M. Methods for simulating the dynamics of complex biological processes. (panmental.de)
  • Abstract: Complex processes, whether natural or artificial, often exhibit inherent variability and result in slightly different products even when identical steps, equipment, materials and conditions are employed. (usc.edu)
  • It mainly acts on biological processes such as inflammatory response, chemokine metabolic process, and immune response as well as pathways such as FoxO signaling pathway, Yersinia infection, HIF-1 signaling pathway, and TNF signaling pathway. (hindawi.com)
  • Engineering living systems that mimic key biological processes is a major challenge. (europa.eu)
  • These artificial cell systems have the potential to increase understanding of biological and cellular processes, while also having potential applications in healthcare technologies. (europa.eu)
  • Mimicking natural processes used by viruses, a flexible new platform developed by Northwestern University synthetic biologists binds to target cells and effectively transfers biological treatments inside. (northwestern.edu)
  • But many fundamental biological processes that involve, for example, the conversion of light into energy forms that are usable for chemical transformations are quantum mechanical in their nature. (cecam.org)
  • One institute is focused on studying the basis of intelligence in natural and artificial systems, and the other is developing technologies to observe the biological processes happening inside our cells. (upworthy.com)
  • Underlying biological processes involve induced massive deposition of extracellular matrix (ECM) by aberrant fibroblasts. (lu.se)
  • Before moving to Lund, Peter did a three year postdoctoral stay in Cambridge, UK, where he worked with Prof. David Klenerman on developing new tools to study biological processes on the surface of cells. (lu.se)
  • Beyond expanding support for its science and science technology programs, CZI is supporting the creation of new scientific institutes to take on grand scientific challenges in areas such as imaging, artificial intelligence, infectious disease research, cell biology, and neuroscience while building new technologies and tools to tackle them. (eurekalert.org)
  • The Kempner Institute for the Study of Natural and Artificial Intelligence at Harvard University. (eurekalert.org)
  • How can the application of artificial intelligence to biological imaging create new insights into how cells and tissues function? (eurekalert.org)
  • We've been astonished by the fact that methods in single-cell biology, microscopy, and artificial intelligence that were considered impossible just five years ago are now routine. (eurekalert.org)
  • Using large data science, artificial intelligence and deep learning, we use medical image data to tackle some of the most pressing healthcare questions to date. (edu.au)
  • This research is important because it demonstrates the ability of artificial intelligence algorithms to accelerate wet lab research discoveries. (neurosciencenews.com)
  • Five of these genes had never been examined in ALS, indicating that IBM's artificial intelligence platform could predict novel genes and proteins linked to this disease. (neurosciencenews.com)
  • Artificial intelligence has gained more than a foothold in drug research laboratories despite an initial wave of skepticism and concern over machines taking the jobs of scientists. (acs.org)
  • Artificial intelligence raises a lot of questions and a lot of anxiety, each new advance fostering both enthusiasm and skepticism. (acs.org)
  • The artificial intelligence-powered swimmer switches between different modes of locomotory gaits (color-coded) autonomously in tracing a complex trajectory "SWIM. (techbriefs.com)
  • On November 10, the Gender Equity Initiative at Northwestern Pritzker School of Law and the Northwestern University Law and Technology Initiative cohosted the "Gender and Intersectional Bias in Artificial Intelligence Conference. (northwestern.edu)
  • Martin reports that new hire Michael Hallett, a professor in the Department of Biology, will be exploring machine learning and artificial intelligence. (concordia.ca)
  • With the recent adoption of artificial intelligence (AI) in healthcare, these logical systems are aimed towards finding an early diagnosis of cognitive decline. (ucla-mls.com)
  • Our major areas of focus revolve around math-computation, modeling, and artificial intelligence. (medlineplus.gov)
  • Fibrotic Pattern Detection by Artificial Intelligence identified tranilast as an effective inhibitor. (lu.se)
  • Pauline Kergus uses artificial intelligence to model the thermal behavior of buildings. (lu.se)
  • Fabian Theis uses artificial intelligence to unlock the secrets of human cells. (lu.se)
  • Fabian is the director of the Institute of Computational Biology at the Helmholtz Center Munich and scientific director of the Helmholtz Artificial Intelligence Cooperation Unit (HelmholtzAI) which was launched in 2019. (lu.se)
  • and University California, San Francisco, to take on large-scale scientific challenges in areas like cell biology and infectious disease research. (eurekalert.org)
  • In addition to expanding our support for our core scientific programs in neurodegeneration, single-cell biology, imaging, open science, rare disease research, and infectious disease research, over the next 10 years, CZI Science will focus on building new tools and technologies to measure human biology in action to benefit human health. (eurekalert.org)
  • In biology, cells use a variety of mechanisms to deal with sudden changes in their surroundings. (sciencedaily.com)
  • The Biological and Biomedical Engineering (BBME) Master's program focuses on the interdisciplinary application of methods, paradigms, technologies, and devices from engineering and the natural sciences to problems in biology, medicine, and the life sciences. (mcgill.ca)
  • Candidates should hold a bachelor's degree in engineering, science, or medicine with a strong emphasis on mathematics, physics, chemistry, and basic physiology or cell biology. (mcgill.ca)
  • In Methods in cell biology , 84: 807-842, 2008. (panmental.de)
  • Lastly, in the context of synthetic biology, using amplicon sequencing data from multiple cell lines (i.e. (usc.edu)
  • This provides an unprecedented level of control over the way the protein interacts with other components of the cell, and will allow us to begin tackling unsolved - and previously unsolvable - problems in biology, with important implications for medicine and industry. (ucsf.edu)
  • The proposed research project is strongly multidisciplinary, and involves a combination of polymer chemistry, nanomaterials engineering, cell biology, and imaging techniques. (europa.eu)
  • As described on the CASB's website , synthetic biology involves the genetic modification of micro-organisms in order "to design and build biological systems that are beneficial to society. (concordia.ca)
  • Aashiq H. Kachroo, assistant professor in the Department of Biology, is looking to engineer human biological systems in simple cells like baker's yeast. (concordia.ca)
  • His work attempts to engineer human biological systems "in simple cells like baker's yeast," research that could be applied to "understanding basic biology such as evolution and applied sciences like fighting disease," Kachroo explains. (concordia.ca)
  • Synthetic biology seeks to build non-natural systems by adding DNA sequences-effectively, little genetic "programs"-to well-studied cells such as E. coli and yeast. (technologyreview.com)
  • Prof. Atan Gross has, for the past several years, been focusing on a pair of cell suicide proteins - BID and ATM. (scienceblogs.com)
  • Using engineered proteins, MIT researchers have designed a system in which they can record "memories" of sequences of cellular events, such as when certain genes are activated, or how cells respond to a drug, as cells turn on series of genes and pathways in performing functions. (scienceboard.net)
  • These RNA binding proteins play a critical role in how genes encoded within the DNA in every cell are converted to the proteins that perform all the functions within a cell. (neurosciencenews.com)
  • The Barrow team validated the top 10 RNA binding proteins using five different methods that included use of patient tissue samples and patient derived stem cells differentiated into motor neurons. (neurosciencenews.com)
  • In the first of the two new papers, the researchers describe arms that can direct molecular traffic inside cells, degrade specific proteins, and initiate the cell's self-destruct process. (ucsf.edu)
  • Once it was discovered that DNA contains the instructions for making cells and proteins, the way was open for many diverse engineering applications. (teachengineering.org)
  • Using artificial proteins and hormones as a means of communication, Vergil had "trained" the lymphocytes in the past six months to interact as much as possible with each other and with their environment - a much more complex miniature glass maze. (technovelgy.com)
  • Junghans V, Santos AM, Lui Y, Davis SJ, Jönsson P, "Dimensions and interactions of large T-cell surface proteins" Front. (lu.se)
  • Ricin causes toxicity by inhibiting the formation (synthesis) of proteins in the cells of the exposed individual. (cdc.gov)
  • How do interactions between cancer cells, surrounding tissues, and the immune system promote or prevent tumor growth? (eurekalert.org)
  • We investigate the effects of local heating from gold nanoparticles irradiated by lasers on biological cells and tissues. (edu.au)
  • The real-time technique images millimeter-scale regions to assess the viability of the cells and how the cells are distributed within the scaffold-an important capability for researchers who manufacture complex biological tissues from simple materials such as living cells. (phys.org)
  • University of Illinois scientists have developed a tiny mechanical probe that can measure the inherent stiffness of cells and tissues, as well as the internal forces that cells generate and exert upon one another. (scienceboard.net)
  • The stiffness levels and distributions of biological materials reflect disease-related information, from cells to tissues. (reachmd.com)
  • These subsystems are groups of cells that work together to form tissues and organs that are specialized for particular body functions. (teachengineering.org)
  • Others communicate with cells in the same or different tissues. (nanoappsmedical.com)
  • The study, published January 12 in the journal Cell Stem Cell , holds potential for new neurodegenerative disease therapies. (scienceboard.net)
  • Smidt Heart Institute scientists have investigated how biological pacemaker cells fight back against RNA therapies to correct abnormal heartbeat rates. (scienceboard.net)
  • By accelerating cell biological research, scientists hope to speed the discovery of new therapies for ALS. (neurosciencenews.com)
  • Current therapeutic options for SS mainly relies on improving mouth and eye dryness and suppressing immune responses, such as artificial tears and saliva substitutes, nonsteroidal anti-inflammatory drugs, glucocorticoids, hydroxychloroquine, synthetic immunosuppressive agents, and T or B cell-targeting biological therapies [ 12 ]. (hindawi.com)
  • For instance, when the level of dissolved nutrient molecules (e.g., sugar) in the cell's watery environment drops, water flows into the cell through osmosis. (sciencedaily.com)
  • The method is also label-free: Cells did not need fluorescent molecules known as "labels" to be attached to them in order to be seen. (phys.org)
  • A 'key' (black) unlocks a 'cage' (grey), revealing a bioactive peptide (yellow) which can interact with other molecules in the cell. (ucsf.edu)
  • Most calculations on large chemical and/or biological molecules use classical molecular dynamics up to now. (cecam.org)
  • As part of a goal to create what she calls "super skin," Stanford researcher Zhenan Bao is now giving the artificial skin the ability to detect chemical and biological molecules. (innovationtoronto.com)
  • To enhance the skin and give it the ability to sense a particular biological or chemical molecule, it needs to be coated with another molecule that will bind with the biological or chemical molecules when they come in contact. (innovationtoronto.com)
  • She was exploring how immune cells react to foreign molecules. (nanoappsmedical.com)
  • Using electron microscopy, she saw how cells ingested these molecules, which became stuck to the surface of tiny intracellular vesicles. (nanoappsmedical.com)
  • They are produced by machinery inside the cell that traffics molecules and particles to where they need to be. (nanoappsmedical.com)
  • During this time he also had the opportunity to collaborate with Prof. Yuri Korchev's group at Imperial College London, UK, on using nm- to µm-sized pipettes to manipulate and stimulate molecules on cells. (lu.se)
  • Together with researchers in Prof. Klenerman's group and in Prof. Davis' group he has investigated how molecules on the surface of cells in the adaptive immune system behave and organize at the start of an immune response. (lu.se)
  • Molecular motors are large molecules that carry out mechanical tasks in living cells. (lu.se)
  • which can be considered a sort of foundational paper for (or even the manifesto of) the modern approaches for constructing living artificial cells from scratch. (frontiersin.org)
  • 2D approaches also don't work quite as well because they don't closely mimic the 3D microenvironment that cells experience in the body, said Babakhanova. (phys.org)
  • Also, scientists will need to improve the methods used to deliver cells to desired locations within the heart, as well as the recovery of specific individual cells for detailed characterization and functional analyses. (sciencedaily.com)
  • Using a similar pressure-regulating mechanism to that found in cells, scientists created an artificial cell that responds to a sudden and possibly catastrophic change in its surroundings. (sciencedaily.com)
  • For decades scientists have been trying to reproduce cell culture environment for the closest mimicry of the natural cellular "embedding" within a living organism. (selectbiosciences.com)
  • According to a paper by Weizmann Institute scientists that appeared today in Nature, artificial sweeteners not only encourage the wrong kind of bacteria to expand their numbers, they also induce mix-ups in the cross-communication between these bacteria and your body. (scienceblogs.com)
  • Now, scientists at the National Institute of Standards and Technology (NIST), the U.S Food and Drug Administration (FDA) and the National Institutes of Health (NIH) have developed a noninvasive method to count the live cells in a three-dimensional (3D) scaffold . (phys.org)
  • With LOCKR, a switch-like protein, scientists can finally build the biological equivalent of such circuits inside cells. (ucsf.edu)
  • Other scientists jumped on the concept, and began to find exosomes being spat out from all kinds of cell. (nanoappsmedical.com)
  • Scientists are learning ever more about how vesicles move in and out of cells and across the complex terrain between them, as well as about the roles of vesicles in health and disease. (nanoappsmedical.com)
  • Single-stranded DNA (ssDNA) can pass through αHL, a biological nanopore, incorporated in bilayer lipid membranes (BLMs), whereas double-stranded DNA (dsDNA) cannot. (elsevierpure.com)
  • We use computational modelling as well as artificial lipid membrane systems developed by our partners at Surgical Diagnostics Pty Ltd and UTS. (edu.au)
  • Peter graduated as PhD in Physics from Chalmers, Sweden, in 2010 under the supervision of Prof. Fredrik Höök , where he got to work with artificial model systems of a cell membrane, so called supported lipid bilayers, and with fluorescence microscopy, two techniques that have become central for his work since then. (lu.se)
  • Dam T, Junghans V, Humphrey J, Chouliara M, Jönsson P, "Calcium Signaling in T Cells Is Induced by Binding to Nickel-Chelating Lipids in Supported Lipid Bilayers" Front. (lu.se)
  • Can stem cell technology be harnessed to generate biological pacemakers? (sciencedaily.com)
  • A new article highlights the promise and limitations of new methods based on stem cell and reprogramming technologies to generate biological pacemakers that might one day replace electronic pacemakers. (sciencedaily.com)
  • To create biological pacemakers, one approach is to coax stem cells to become specialized cardiac pacemaker cells that are normally found within the sinoatrial node of the heart. (sciencedaily.com)
  • We are working to generate red blood cells in vitro from pluripotent stem cells, however the extremely large cell numbers involved pose unique challenges to culture technology and scale-up. (selectbiosciences.com)
  • Novel culture and cryopreservation systems for human pluripotent stem cells and neural stem cells will be presented and their advantages and applicability in the production of high quality advanced therapeutic products or functional screening tools for preclinical research discussed. (selectbiosciences.com)
  • The opportunities and challenges of development of stem cell-based therapeutic interventions for joint surface repair for the treatment and prevention of osteoarthritis will be discussed. (selectbiosciences.com)
  • This presentation describes the current state of the stem cells marketplace as it relates to their utilization for pharmaceutical screening as well as their development for cellular therapy. (selectbiosciences.com)
  • Details are provided about the quantitative market opportunity for various stem cell classes as well as the current state of the clinical trials space wherein stem cell-based therapeutics are being evaluated for therapy in various disease classes. (selectbiosciences.com)
  • Stem cell-based regenerative medicine shows much promise. (selectbiosciences.com)
  • This presentation will describe the current status of strategies to generate induced pluripotent stem (iPS) cells from mouse and human somatic cells for patient-specific disease modeling and cell therapeutic applications. (selectbiosciences.com)
  • We will discuss our recent findings in the use of novel chemistry and physical energy, including radioelectric conveyed fields, to optimize stem cell expression of pluripotentiality. (selectbiosciences.com)
  • Clinical use of human embryonic stem (hES) cells is already being explored in a several phase1 safety trials. (selectbiosciences.com)
  • and more recently we have seen 'futuristic' developments including stem cell engineering and the 3-D printing of biological organs. (imperial.ac.uk)
  • Northwestern University-led researchers have created the first highly mature neurons from human induced pluripotent stem cells. (scienceboard.net)
  • Manipulation of magnetic microdroplets has revealed how stem cells in a living embryo mechanically test their environment to communicate with neighboring cells. (scienceboard.net)
  • The number of direct-to-consumer companies peddling EV treatments without proof of safety or efficacy is shocking," says stem-cell biologist Darius Widera at the University of Reading, UK. (nanoappsmedical.com)
  • Another promising approach is to directly reprogram supporting cells, already present in the heart--for instance, fibroblasts (e.g., connective tissue)--and convert them into pacemaker cells to restore cardiac function. (sciencedaily.com)
  • For example, researchers need to better understand the mechanisms controlling the development and maintenance of pacemaker cells in the sinoatrial node, just as they must develop ways to compare experimental biological pacemaker tissue with bona fide sinoatrial node tissue. (sciencedaily.com)
  • The incidence of keratinocyte cancer (basal cell and squamous cell carcinomas of the skin) is 17-fold lower in Singapore than the UK, despite Singapore receiving 2-3 times more ultraviolet (UV) radiation. (cdc.gov)
  • This is helping accelerate the growth of engineered biological systems that span from one single cell all the way to multicellular systems, like engineered organs. (medlineplus.gov)
  • The developed artificial tactile neuron device is a high-response, high-sensitivity device that allows the pressing force to generate faster electrical spikes while improving the pressure sensitivity, which focuses on the fact that stiffer materials result in faster pressure sensing when pressed. (reachmd.com)
  • Nearly all types of cell (including those from plants, fungi and bacteria) generate a rich variety of vesicles. (nanoappsmedical.com)
  • Teams led by Dr. Hyunjung Yi and Suyoun Lee have developed a simple but highly accurate disease diagnosis technology by combining tactile neuron devices with artificial neural network learning methods. (reachmd.com)
  • The researchers adjusted the particle output of the signaling cell to create various cell formations, some of which are shown in the videos available on Pitt's Web site and with this release. (nanowerk.com)
  • Nov. 10, 2022 Researchers have discovered a new process that uses fuel to control non-living materials, similar to what living cells do. (sciencedaily.com)
  • Researchers used a noninvasive and label-free method called optical coherence tomography to assess the live cells in the 3D scaffold system. (phys.org)
  • But to evaluate how successfully the cells develop into tissue, researchers need a reliable method to monitor the cells as they move and multiply. (phys.org)
  • The researchers detected organelle motion by shining light through the cells. (phys.org)
  • Researchers at Sweden's Linköping University have created an artificial neuron that closely mimics the characteristics of biological nerve cells. (scienceboard.net)
  • Researchers devised "smart" cells that behave like tiny autonomous robots which may be used to detect damage and disease, and deliver help at just the right time and in just the right amount. (ucsf.edu)
  • In theory, using a biocomputer as the calculation mechanism, researchers could build biosensors or medicine delivery systems that could single out specific cell types in the body. (technovelgy.com)
  • The researchers created what they called an "artificial neuromuscular junction" composed of muscle cells and a nano-sized polymer placed on a biological scaffold. (medindia.net)
  • Researchers establish connections between Alzheimer's-linked genetic alterations and the functioning of brain cells. (medindia.net)
  • The touch-sensitive flexible organic transistor previously developed by the Stanford researchers forms the foundation of the new artificial skin. (innovationtoronto.com)
  • Researchers want to know why cells produce tiny packages called vesicles - and whether these bundles could be used for therapy. (nanoappsmedical.com)
  • Alzheimer's disease (AD) is an ascending, neurodegenerative disorder that attacks the brain's nerve cells, i.e., neurons, resulting in loss of memory, language skills, and thinking and behavioural changes. (researchgate.net)
  • The team added, "Through follow-up research, it will be possible to solve the noise reflection issue, which is a disadvantage of ultrasound elastography if artificial tactile neurons can collect an object's elastography image obtainable using ultrasound elastography. (reachmd.com)
  • They describe the work in a study, published recently in Nature Materials , indicating that the artificial neuron can stimulate natural nerves, making it a promising technology for various medical treatments. (scienceboard.net)
  • Unlike the previously reported artificial tactile neuron devices, this tactile neuron device can determine the stiffness of objects. (reachmd.com)
  • The research team developed an artificial tactile neuron device with a simple structure that combines a pressure sensor and an ovonic threshold switch device to produce such sensory neuron characteristics. (reachmd.com)
  • The KIST research team stated, "the developed artificial tactile neuron technology is capable of detecting and learning mechanical properties with a simple structure and method. (reachmd.com)
  • Although today's pacemakers are lifesaving electronic devices, they are limited by their artificial nature. (sciencedaily.com)
  • Theoretically, biological pacemakers, which are composed of electrically active cells that can functionally integrate with the heart, could provide natural heart rhythm regulation without the need for indwelling hardware," says author Vasanth Vedantham, of the University of California, San Francisco. (sciencedaily.com)
  • Vedantham states that initial large animal studies on biological pacemakers have generated promising results but that much more work remains ahead before biological pacing can be actually considered a clinically viable therapy. (sciencedaily.com)
  • Biological pacemakers must meet a very high standard of performance to supplant electronic pacemakers," Vedantham says. (sciencedaily.com)
  • Physiologist Torsten Thunberg constructed the barospirator, the first device for artificial respiration. (lu.se)
  • The scaffold holds things in place, and it provides a micro-environment for whatever you want from cells. (phys.org)
  • You could tune the scaffold to direct cells to behave in a certain way," said NIST biologist Carl Simon. (phys.org)
  • In the meantime, the method already meets an unmet need in tissue engineering, with its ability to monitor the number and arrangement of cells in an artificial scaffold without having to disassemble and destroy it. (phys.org)
  • The muscle cells on the scaffold and in the body bonded and the body's native nerve sprouts fed electrical impulses into the tissue, creating a stable nerve-muscle connection. (medindia.net)
  • Several (unsuccessful) attempts to build cell-like systems of minimal complexity fill the annals of science ( Hanczyc, 2009 ). (frontiersin.org)
  • In Artificial Life XI: Proceedings of the Eleventh International Conference on the Simulation and Synthesis of Living Systems , pages 297-304, MIT Press, Cambridge, MA, 2008. (panmental.de)
  • In Artificial Life X : Proceedings of the Tenth International Conference on the Simulation and Synthesis of Living Systems , pages 22-27, The MIT Press (Bradford Books), 2006. (panmental.de)
  • Quantum coherences and their effects on spectroscopy of large molecular aggregates are a very exciting issue these days due to recent experimental progress on both biological and synthetic samples showing unexpected long coherence times in large disordered systems. (cecam.org)
  • This workshop aims on bringing those people together who work on biological and/or synthetic systems to discuss and exchange ideas how to most efficiently and accurately solve the above mentioned problems. (cecam.org)
  • An important application in the described field of research are biological as well as artificial light-harvesting systems and solar cells. (cecam.org)
  • At Concordia's new high-tech Genome Foundry, robotics, automation and interdisciplinary research are helping make the university a leader in the process of designing and building DNA and biological systems. (concordia.ca)
  • Where I think we can excel is to use the Genome Foundry to build human biological systems, not just one gene but multiple genes," he says. (concordia.ca)
  • It's clear, then, that the potential range of what biological systems could do is enormous. (technologyreview.com)
  • He is a full professor at the Technical University of Munich, holding the chair 'Mathematical Modelling of Biological Systems', associate faculty at the Wellcome Trust Sanger Institute as well as adjunct faculty at the Northwestern University. (lu.se)
  • These attempts share a common anti-vitalistic viewpoint: synthesizing (cellular) life from scratch should be possible, and it would demonstrate that the biological phenomenology follows a "continuity principle" with respect to physics and chemistry. (frontiersin.org)
  • Joachimczak, M. and Wrobel, B. Evo-devo in silico: a model of a gene network regulating multicellular development in 3D space with artificial physics. (panmental.de)
  • Recent technological breakthroughs, such as ultra-fast pulsed lasers, high-performance computing and crystallography of macromolecules, helped to improve the experimental tools of physicists, biologists, and chemists working, in particular, in the area of chemical and biological physics. (cecam.org)
  • Often atomic-level details are known from experiments in chemical and biological physics these days. (cecam.org)
  • For example, in biological physics these details are mainly obtained by x-ray crystallography of a crystallized version of the macromolecules. (cecam.org)
  • Not only that, she has also developed a new, stretchable solar cell that can be used to power the skin, opening up the possibility of an artificial skin for robots that can be used to power them and enable them to detect dangerous chemicals or diagnose medical conditions with a touch. (innovationtoronto.com)
  • New research says that the brain can achieve motor memory with a prosthetic device, providing hope that physically disabled people can one day master control of artificial limbs with greater ease. (medindia.net)
  • The aim is to share information across labels to improve our estimates of the biological variability in cell abundance between replicates. (bioconductor.org)
  • It was a demonstration that these extracellular vesicles (EVs, also known as exosomes) might be transmitting information between cells. (nanoappsmedical.com)
  • Biological and Biomedical Engineering (BBME) is an interfaculty graduate program administered jointly by the Departments of Bioengineering (Faculty of Engineering) and Biomedical Engineering (Faculty of Medicine and Health Sciences) at McGill. (mcgill.ca)
  • Recently reported in the Proceedings of the National Academy of Sciences (PNAS), the research is a significant step toward producing synthetic cells that behave like natural organisms and could perform important, microscale functions in fields ranging from the chemical industry to medicine. (nanowerk.com)
  • Now, a team of bioengineers led by UC San Francisco's Hana El-Samad, PhD, and the University of Washington's David Baker, PhD, have devised a remarkable solution to this problem - "smart" cells that behave like tiny autonomous robots which, in the future, may be used to detect damage and disease, and deliver help at just the right time and in just the right amount. (ucsf.edu)
  • Protein channels in the cell's membrane release the excess water, preventing catastrophic expansion and bursting of the cell. (sciencedaily.com)
  • Exosomes are held in larger packages, which move to the cell membrane, fuse with it and release the vesicles to the outside. (nanoappsmedical.com)
  • Targeting a cell surface protein could eliminate the lung cancer cells that survive treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), according to a paper published on Monday in Cancer Cell . (scienceboard.net)
  • The white dots are the insulin-containing vesicles inside the beta cells, which both sense glucose levels and secrete insulin. (scienceblogs.com)
  • The proposed approach is inspired by exosomes, cell-secreted vesicles that carry various macromolecules and facilitate intercellular communication. (europa.eu)
  • The cells then spat out the vesicles, along with the foreign cargo, and Raposo captured them. (nanoappsmedical.com)
  • Nanotechnology an be used to create a biological computer that can solve certain mathematical problems far faster and more energy-efficiently than conventional electrical computers. (lu.se)
  • With each pulse, a bit of the excess contents were released and a cyclical breathing-like change in the artificial cell's texture was produced. (sciencedaily.com)
  • We found that noise exposure increases phosphorylation of CFTR at serine 737 (p-CFTR, S737), which reduces wildtype CFTR function, resulting in oxidative stress in cochlear sensory hair cells. (bvsalud.org)
  • This study leveraged data from the Multi-Ethnic Study of Atherosclerosis (MESA) on experiences of threat and deprivation in participants' early lives (i.e., before the age of 18) to examine whether exposure to specific dimensions of early life adversity are associated with epigenetic profiles at older ages that are indicative of accelerated biological aging. (cdc.gov)
  • Mr. Charp skips to "Recent research has demonstrated that a low dose of ionizing radiation under 0.1 Gray (which is 10 rads) activates a unique set of genes in a cell. (cdc.gov)
  • Mr. A. L. Brooks also states "However, there are situations under high LET radiation, such as alpha radiation, that a cell doesn't have to be hit by the radiation in order to have some effect, the bystander effect. (cdc.gov)
  • Outside the cell myosin can be used to move protein filaments, composed of actin, along artificial paths, which direct the filaments' movements. (lu.se)
  • The world's first clinically usable artificial kidney was developed by professor of medicine Nils Alwall . (lu.se)
  • Cells off themselves for any number of reasons: In embryonic development, cell suicide helps shape the growing organism. (scienceblogs.com)
  • This is, at heart, an engineering problem, one that requires both new "software" (new sequences of DNA) and new hardware (the DNA itself-and the methods for putting it into cells). (technologyreview.com)
  • As the signaling cell (right) emits the agonist nanoparticles (shown as blue), the target cell (left) responds with antagonists (shown as red) that stop the first cell from secreting. (nanowerk.com)
  • These molecular doctors could target only cancerous cells, for example, ignoring healthy ones. (technovelgy.com)
  • Just two years later, together with her colleagues, Raposo, who is now at the Curie Institute in Paris, found that exosomes derived from antitumour immune cells could be enlisted to suppress cancers in mice 2 . (nanoappsmedical.com)
  • That implied that exosomes might influence gene expression when they reached their destination cells. (nanoappsmedical.com)
  • Lun, Richard, and Marioni 2017 ) where it is routinely used to examine the effects of different conditions on the composition of complex cell populations. (bioconductor.org)
  • Numerous experiments have shown that B cells collaborate with T cells to activate in response to autoantigens in this disease, resulting in lymphocyte infiltration and immune complex deposition [ 6 ]. (hindawi.com)
  • The research could lead to future biomedical applications of artificial micro-swimmers in complex media with uncontrolled and unpredictable environmental factors. (techbriefs.com)
  • This is the first step in tackling the challenge of developing micro-swimmers that can adapt like biological cells in navigating complex environments autonomously, according to the team. (techbriefs.com)
  • Such adaptive behaviors are crucial for future biomedical applications of artificial micro-swimmers in complex media with uncontrolled and unpredictable environmental factors. (techbriefs.com)
  • Results have the potential to increase understanding of biological mechanisms in relation to the complex hurdle of the nucleic acid based transfer, whilst also providing innovative platform material for treatment of disease. (europa.eu)
  • Today, Chan Zuckerberg Initiative (CZI) co-founders and co-CEOs Dr. Priscilla Chan and Mark Zuckerberg announced that they are doubling down on their commitment to accelerating biomedical science and advancing human health with an ambitious new effort to observe, measure, and analyze any biological process throughout the human body - across spatial scales and in real time. (eurekalert.org)
  • The 3D hydrogel was then embedded with a type of human white blood cell that can reproduce endlessly. (phys.org)
  • Amazingly, this can be accomplished without any direct human intervention thanks to a first-of-its-kind artificial protein - designed on a computer and synthesized in the lab - that can be used to build brand-new biological circuits inside living cells. (ucsf.edu)
  • Human viral infection of artificial origin, likely developed as a bioweapon during the 300's. (orionsarm.com)
  • Each human cell already has all of the tools required to build these biocomputers on its own, says Harvard s Benenson. (technovelgy.com)
  • Benson and colleagues claim to demonstrate that biocomputers can work in human kidney cells in a culture. (technovelgy.com)
  • Hylonano or bionano devices existing inside living cells, participating in their biochemistry (like mitochondria) and/or assembling various structures. (orionsarm.com)
  • Our previous research found that inhibition of the AMP-activated protein kinase alpha subunit (AMPKα) protects against noise-induced cochlear hair cell loss and hearing loss by reducing ROS accumulation. (bvsalud.org)
  • "Effects of a local auxiliary protein on the two-dimensional affinity of a TCR-peptide MHC interaction" J. Cell Sci. (lu.se)
  • 2019 ) . In this case, we are aiming to identify labels that change in abundance among the compartment of injected cells compared to the background. (bioconductor.org)
  • Peripheral blood biomarkers of cell-specific autoimmunity. (lu.se)
  • Appropriate cell-free in vitro models are needed to study bioavailability of a material in a target biological compartment. (cdc.gov)
  • Autopoiesis thus becomes a convenient and elegant theoretical framework to guide the variegate experimental efforts to fabricate synthetic (artificial) cells (SCs/ACs), especially with respect to studies oriented at the origins and emergence of life. (frontiersin.org)
  • And with a nod to ants, the cells leave chemical trails as they travel, prompting fellow microcapsules to follow. (nanowerk.com)
  • First Responders should use a NIOSH-certified Chemical, Biological, Radiological, Nuclear (CBRN) Self Contained Breathing Apparatus (SCBA) with a Level A protective suit when entering an area with an unknown contaminant or when entering an area where the concentration of the contaminant is unknown. (cdc.gov)
  • Their research was conducted on mice, but if found to be true for humans as well, it may have clinical implications in the way patients could be treated for fatty liver and other metabolic diseases, which are characterized by abnormally elevated levels of lipids in blood and liver cells. (scienceblogs.com)
  • Any changes we detect between conditions will subsequently represent differences in the proportion of cells in each cluster. (bioconductor.org)
  • It can be difficult enough to see whole cells under a microscope, let alone detect the nanoscale particles that they eject. (nanoappsmedical.com)
  • Cells can be very sensitive to the environment in which they're grown: If a researcher wants to study the growth of bone cells instead of breast tissue , they need to be cultured in different conditions. (phys.org)
  • The EU-funded RNAhello project seems to have found a way to study RNA-based communication in artificial protocells. (europa.eu)
  • In this study, we have investigated a potential target of AMPKα and ROS, cystic fibrosis transmembrane conductance regulator (CFTR), and the protective effect against noise-induced hair cell loss of an FDA-approved CFTR potentiator, ivacaftor, in FVB/NJ mice, mouse explant cultures, and HEI-OC1 cells. (bvsalud.org)
  • Leukocyte-platelet-rich plasma (L-PRP) is a bloodderived portion composed of high concentrations of platelets and white cells, and it has been applied as autogenous biomaterial in bone repair 13 . (bvsalud.org)
  • With a special emphasis on bioheat transfer, our aim is to destroy cancer cells or bacteria. (edu.au)