• Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is disease of the arteries in the brain, which causes tissue loss in the subcortical region of the brain and the destruction of myelin in the CNS. (wikipedia.org)
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common form of hereditary cerebral angiopathy (see image below). (medscape.com)
  • FLAIR MRI of the brain showing hyperintensities involving the temporal poles in a patient with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). (medscape.com)
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12. (medscape.com)
  • the NOTCH3 gene have been found to cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy , commonly known as CADASIL. (nih.gov)
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an arteriopathic syndrome related to a genetic defect on chromosome 19. (ajnr.org)
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) has recently been described as a hereditary microangiopathic condition leading to cerebrovascular symptoms in the third to fourth decade of life (1, 2) . (ajnr.org)
  • Alqarni AA, Shirah B, Algahtani H, Almohiy H, Hassan A. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: Atypical clinical presentation with isolated frontotemporal dementia. (ruralneuropractice.com)
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary syndrome caused by heterozygous mutations in the NOTCH3 gene that manifests in adulthood and is characterized by recurrent transient ischemic attacks and strokes, migraine-like headaches, psychiatric disturbance, and progressive dementia. (ruralneuropractice.com)
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, usually called CADASIL, is an inherited condition that affects small arteries (blood vessels) mainly in the brain. (goldbamboo.com)
  • Described by Joutel et al , 3 cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a Mendelian form of hereditary small-vessel disease and vascular dementia. (bmj.com)
  • It is an occlusive arteriopathy involving small-caliber vessels. (medscape.com)
  • Variously described as a vasculopathy, endovasculitis, or occlusive arteriopathy, this condition occurs in a benign cutaneous form and a lethal multiorgan systemic variant. (bvsalud.org)
  • These findings are consistent with transplant arteriopathy which represents chronic vascular damage, usually in the setting of antibody-mediated rejection. (arkanalabs.com)
  • Identification of missed hypertension and hypertensive arteriopathy with home versus ambulatory blood pressure measurement in patients with tia or minor stroke. (ox.ac.uk)
  • Given high rates of under-treatment of hypertension in secondary prevention after TIA and stroke, we compared Bluetooth home BP monitoring (HBPM) and ABPM in identifying hypertension missed at initial assessment, with validation against pre-morbid BP and markers of hypertensive arteriopathy. (ox.ac.uk)
  • CBAs may not be a significant cause of ICH but are a manifestation of severe cerebral small vessel disease including both hypertensive arteriopathy and CAA. (nature.com)
  • Systemic proliferative arteriopathy and hypophysitis in a cow with chronic ovine herpesvirus 2-induced malignant catarrhal fever. (tamu.edu)
  • Here we present a case of chronic MCF in a cow with proliferative arteriopathy, systemic vasculitis, and OvHV2-associated hypophysitis. (tamu.edu)
  • Mycophenolate mofetil also inhibited proliferative arteriopathy in experimental models of aortic and cardiac allografts in rats, as well as in primate cardiac xenografts. (nih.gov)
  • Thus I would like to conclude by saying that an idiopathic form of obliterative renal arteriopathy account for the rare presentation of severe hypertension and progressive renal failure with or without overt hemolytic anemia and thrombocytopenia in children. (jpgmonline.com)
  • Persistent or recurrence of this process form the basis of progressive obliterative arteriopathy. (jpgmonline.com)
  • To identify cerebral aneurysmal arteriopathy in children with longstanding AIDS. (neurology.org)
  • The development of cerebral aneurysmal arteriopathy in childhood AIDS tends to occur after a prolonged delay and is usually followed by death in a short period of time. (neurology.org)
  • L'objectif de ce protocole national de diagnostic et de soins (PNDS) est d'expliciter pour les professionnels de santé la prise en charge optimale et le parcours de soins des patients atteints de CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leucoencephalopathy). (has-sante.fr)
  • Plexogenic pulmonary arteriopathy is an arterial disease develop in individuals with long-standing pulmonary hypertension. (medicotips.com)
  • Once a diagnosis of aneurysmal arteriopathy was made, the patients deteriorated rapidly, with death occurring in less than 6 months. (neurology.org)
  • Diagnostic approach and proposed criteria for the clinical diagnosis of Takayasu's arteriopathy. (nih.gov)
  • Methods The Genetic Epidemiology Network of Arteriopathy (GENOA) study enrolled sibships between 1997 and 1999, including 1329 hypertensive non-Hispanic blacks (1057 sibling pairs) from Jackson, Mississippi, 1133 hypertensive non-Hispanic whites (859 sibling pairs) from Rochester, Minnesota, and 752 hypertensive Hispanic whites (627 sibling pairs) from Starr County, Texas. (elsevierpure.com)
  • The Genetic Epidemiology Network of Arteriopathy (GENOA) is one of four networks in the NHLBI Family-Blood Pressure Program (FBPP). (nih.gov)
  • Do you have cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) or want to help someone with the condition? (nih.gov)
  • CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy) is a genetic disorder. (nih.gov)
  • Anticoagulation (specifically, with warfarin) may be helpful because evidence suggests that patients with idiopathic PAH (IPAH) develop thrombotic arteriopathy (with abnormalities of blood coagulation factors, antithrombotic factors, and the fibrinolytic system). (medscape.com)
  • The noted idiopathic arteriopathy had disrupted the normal blood supply to the affected area. (avma.org)
  • In the presence of an arteriopathy, however, this risk is increased fivefold versus an "idiopathic stroke," with the highest risk of recurrence within the first three months after the index stroke. (clevelandclinic.org)
  • Arteriopathy increased the risk of recurrence fivefold compared with idiopathic AIS. (clevelandclinic.org)
  • 11. The course and outcome of unilateral intracranial arteriopathy in 79 children with ischaemic stroke. (nih.gov)
  • These blood vessel abnormalities (described as arteriopathy) greatly increase the risk of stroke and lead to the death of nerve cells (neurons) in many areas of the brain. (medlineplus.gov)
  • 6. Predictive validity of severity grading for cerebral steno-occlusive arteriopathy in recurrent childhood ischemic stroke. (nih.gov)
  • 10. Endothelial injury in childhood stroke with cerebral arteriopathy: a cross-sectional study. (nih.gov)
  • 12. Lack of progressive arteriopathy and stroke recurrence among children with cryptogenic stroke. (nih.gov)
  • 13. Quantitative Arterial Tortuosity Suggests Arteriopathy in Children With Cryptogenic Stroke. (nih.gov)
  • 14. Predictors of cerebral arteriopathy in children with arterial ischemic stroke: results of the International Pediatric Stroke Study. (nih.gov)
  • 18. Clinical and Imaging Characteristics of Arteriopathy Subtypes in Children with Arterial Ischemic Stroke: Results of the VIPS Study. (nih.gov)
  • Late delayed effects, occuring several months to many years later are classified into diffuse white-matter injury, radiation-induced arteriopathy & stroke and late delayed radiation necrosis. (cancer.org)
  • VIPS II follows the first VIPS trial, which found that the greatest predictor of stroke recurrence is arteriopathy, underscoring its importance as a target for secondary stroke prevention in this population. (clevelandclinic.org)
  • 16. Focal Cerebral Arteriopathy: Do Steroids Improve Outcome? (nih.gov)
  • He had what is called focal cerebral arteriopathy, a condition responsible for about 35 percent of all pediatric strokes. (childrensmercy.org)
  • One common and unique pattern of arteriopathy seen in children involves a focal narrowing of the distal internal carotid artery, or proximal middle cerebral artery, known as focal cerebral arteriopathy (FCA) of childhood (see image below), notes pediatric cerebrovascular specialist Neil Friedman, MBChB . (clevelandclinic.org)
  • Focal cerebral arteriopathy of childhood. (clevelandclinic.org)
  • The authors report the unique case of a 6-year-old African-American girl with sickle cell disease (SCD) and an associated moyamoya arteriopathy who developed a de novo arteriovenous malformation (AVM) of the cerebral circulation. (elsevierpure.com)
  • One-year recurrence rates were 32 percent for moyamoya, 25 percent for focal or transient cerebral arteriopathy and 19 percent for arterial dissection. (clevelandclinic.org)
  • CARASIL-associated mutant HTRA1 exhibited decreased protease activity and failed to repress transforming growth factor-β family signaling, indicating that the increased signaling causes arteriopathy in CARASIL. (nih.gov)
  • Histopathologic findings for this portion of the bone indicated an arteriopathy-induced focal subchondral osteonecrosis that had resulted in articular surface collapse. (avma.org)
  • A 43-year-old man with typical digital substraction angiographic findings of arteriopathy was admitted to our department after 30 sessions of hyperbaric oxygen therapy. (japmaonline.org)
  • The majority of FMD patients benefit from ongoing medical management by knowledgeable vascular experts with a special interest and training in arteriopathy. (enh.org)
  • NorthShore's Arteriopathy Clinic focuses on the care of patients with diseases of the arteries. (enh.org)
  • Through our Arteriopathy Clinic, we educate patients about the warning signs of severe complications of the disease. (enh.org)
  • Using cutting-edge testing techniques on blood samples and throat swabs from patients, VIPS II investigators anticipate better defining the roles of infection and inflammation on arteriopathy to help inform treatment decisions following an initial AIS. (clevelandclinic.org)
  • In the brain, the resulting blood vessel damage (arteriopathy) can cause migraines, often with visual sensations or auras, or recurrent seizures (epilepsy). (nih.gov)
  • This damage, or arteriopathy appears to cause the arteries to stretch, narrow or kink in such a way that during high-intensity exercise the athlete experiences decreased blood flow due to the constriction or obstruction of the artery in the affected leg. (slowtwitch.com)
  • ELN arteriopathy may be present in a nonsyndromic condition or in syndromic conditions such as Williams-Beuren syndrome. (nih.gov)
  • To the authors' knowledge, this report represented the first description of arteriopathy-induced focal osteonecrosis of the caudomedial aspect of the femoral head and its successful treatment in a young dog. (avma.org)
  • In this article, we report the treatment outcome of a recalcitrant foot ulceration related to lower leg arteriopathy. (japmaonline.org)