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  • renal
  • 2 Renal autoregulation depends primarily on a rapid myogenic contraction of the afferent arteriole 3 followed by a tubuloglomerular feedback response. (ahajournals.org)
  • 1 Reactive oxygen species (ROS) have been implicated in the increased vascular reactivity of the renal afferent arterioles to angiotensin II in states of oxidative stress. (ahajournals.org)
  • 7 Recently, ROS have been implicated in the enhanced myogenic contractions of renal afferent arterioles from spontaneously hypertensive rats (SHRs), 8 although the more modest myogenic contractions of normotensive rats were independent of ROS. (ahajournals.org)
  • The mouse isolated perfused renal afferent arteriole displayed a linear increase in active wall tension above a PP of ≈40 mm Hg, which defined the myogenic response. (ahajournals.org)
  • The afferent arterioles branch from the renal artery, which supplies blood to the kidneys. (wikipedia.org)
  • When renal blood flow is reduced (indicating hypotension) or there is a decrease in sodium or chloride ion concentration, the macula densa of the distal tubule releases prostaglandins (mainly PGI2 and PGE2) and nitric oxide, which cause the juxtaglomerular cells lining the afferent arterioles to release renin, activating the renin-angiotensin-aldosterone system, to increase blood pressure and increase reabsorption of sodium ions into the bloodstream via aldosterone. (wikipedia.org)
  • Drugs, such as the immunosuppressants cyclosporine and tacrolimus, chemo-therapeutic drugs bleomycin and cisplatin, clopidogrel, oestrogen-containing oral contraceptives and quinine may cause thrombosis in the afferent renal arteriole and glomerulus. (thefreedictionary.com)
  • Results indicate that in isolated renal arterioles AP III dilates preconstricted AA but constricts EA that have either not been pretreated or have been preconstricted with other agonists. (physiology.org)
  • Each straight arteriole has a hairpin turn in the medulla and carries blood at a very slow rate - two factors crucial in the maintenance of countercurrent exchange that prevent washout of the concentration gradients established in the renal medulla. (wikipedia.org)
  • Reduced NaCl uptake via the NKCC2 at the macula densa leads to increased renin release, which leads to restoration of plasma volume, and to dilation of the afferent arterioles, which leads to increased renal plasma flow and increased GFR. (wikipedia.org)
  • endothelial
  • Coloured transmission electron micrograph (TEM) of a section through the wall of an arteriole, showing smooth muscle (brown), endothelial cells (green), and an inner and outer lamina (membrane, blue). (sciencephoto.com)
  • Mitochondrial uncoupling agents could potentially reverse endothelial dysfunction due to HG in intact human arterioles. (ahajournals.org)
  • endothelium-dependent
  • Vasomotor function was assessed in response to endothelium-dependent agonists using videomicroscopy of small arterioles from fat. (nih.gov)
  • Pharmacological inhibition of cyclooxygenase with indomethacin improved endothelium-dependent vasodilator function of arterioles from visceral fat by twofold (P = 0.01), whereas indomethacin had no effect in the subcutaneous depot. (nih.gov)
  • diameters
  • 1. Measurements of the internal diameters and lengths of branchless segments of mesenteric arterioles of frogs and mice show those geometrically to be cone-shaped, not cylindrical. (ebscohost.com)
  • Arteriole diameters decrease with age and with exposure to air pollution. (wikipedia.org)
  • tissue
  • The altered coat of the arterioles, consisting of adenoid tissue, presents here and there thickenings of a spheroidal shape, the white pulp. (wikipedia.org)