Arterial walls. Medical search. Frequent questions

An interdisciplinary team of NTU researchers from School of MAE, MSE, LKCMedicine, and Tan Tock Seng Hospital (TTSH) has developed a novel human arterial wall-on-a-chip to study atherosclerosis - a disease manifests in the artery that is mainly responsible for the narrowing of blood vessels and the development of cardiovascular diseases. (ntu.edu.sg)
Arterial inflammation and remodeling, important sequellae of advancing age, are linked to the pathogenesis of age-associated arterial diseases e.g. hypertension, atherosclerosis, and metabolic disorders. (johnshopkins.edu)
Atherosclerosis is a generalized disorder of the arterial tree, manifested by plaque formation along the inner surface of arteries. (encyclopedia.com)
Atherosclerosis occurs when cholesterol, fats, and other substances build up in the arterial wall. (naturalnews.com)

The microfabricated chip is constructed by 3D co-culture of endothelial cells and smooth muscle cells (two major cell types present in the arterial wall) in precisely patterned hydrogels. (ntu.edu.sg)
Macrophages containing brown pigment consistent with hemosiderin (arrows) are present in the arterial wall. (nih.gov)

What is lower extremity arterial bypass? (unmc.edu)

1. Arterial Thrombosis in Cancer: Spotlight on the Neglected Vessels. (nih.gov)
5. Arterial Thrombosis in Cancer Patients: An Update. (nih.gov)
6. Acute Arterial Thrombosis during Postoperative Adjuvant Cisplatin-based Chemotherapy for Completely Resected Lung Adenocarcinoma. (nih.gov)
7. Treatment of multiple myeloma and arterial thrombosis. (nih.gov)
11. Arterial thrombosis with immunomodulatory derivatives in the treatment of multiple myeloma: a single-center case series and review of the literature. (nih.gov)
12. Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study. (nih.gov)
16. Arterial thrombosis in unusual sites: A practical review. (nih.gov)
19. Arterial thrombosis and cancer. (nih.gov)
20. Discrepant ratios of arterial vs. venous thrombosis in hemophilias A and B as compared to FVII deficiency. (nih.gov)
Catheter-Related Arterial Thrombosis in Neonates and Children: A Systematic Review. (medigraphic.com)
Umbilical Arterial Thrombosis with Vascular Wall Necrosis: Clinicopathologic Findings of 11 Cases. (medigraphic.com)

We estimated PPA stiffness (elastic modulus [EM]) and the relative area wall thickness (AWT). (uab.cat)
2020. Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking . (cardiff.ac.uk)
Progressive arterial stiffness with age causes hypertension, a state of chronically raised blood pressure, which in turn damages sensitive tissues in the brain and other organs. (prohealth.com)

These studies suggest that arterial LDL-CE delivery via SU can be an important mechanism in vivo and that dietary influences on arterial LPL levels and atherogenesis modulate arterial LDL-CE delivery, cholesterol deposition, and SU. (jci.org)
In addition, MFG-E8 has been found to be an essential component of the endothelial-derived microparticles that relay biosignals and modulate arterial wall phenotypes. (johnshopkins.edu)

The transcription, translation, and signaling levels of MFG-E8 are increased in aged, atherosclerotic, hypertensive, and diabetic arterial walls in vivo as well as activated vascular smooth muscle cells (VSMC) and a subset of macrophages in vitro. (johnshopkins.edu)
A better understanding of the biomechanical properties of the arterial wall provides important insight into arterial vascular biology under normal (healthy) and pathological conditions. (ncsu.edu)
and vascular smooth muscle cell gene SLC2A10 have all been implicated in at least two types of arterial dissection. (wikipedia.org)
The Wall Center at Stanford was privileged to host four experts in pulmonary vascular medicine from LATAM. (stanford.edu)
The Race Against PH raises funds for the Vera Moulton Wall Center for Pulmonary Vascular Disease and the Ewing Family Fund for PH Research at Stanford. (stanford.edu)
A) MIP from a peripheral CTA (left) shows extensive vascular calcifications that partially obscure the arterial lumen, but are invisible in the MIP of the QISS MRA (right). (biomedcentral.com)
The technology includes MRI methods, systems, and software for reliably imaging vasculature and vascular wall thickness while compensating for aperiodic intrinsic motion of a patient during respiration. (nih.gov)
You may be familiar with bypass surgery on heart arteries, but vascular surgeons also use bypasses to treat peripheral arterial disease (PAD). (unmc.edu)
This arterial disease can occur anywhere along the vascular tree, but occurs more commonly at branch points, where blood vessels bifurcate. (encyclopedia.com)
Vascular smooth muscle cell phenotypic change and consequential intimal hyperplasia (IH) cause arterial stenosis and posttreatment restenosis. (ahajournals.org)

The AVALON Arterial Wall Compliance (AVALON-AWC) trial was based on a unique methodology for measuring the luminal elasticity of both the large and small arteries of patients before and after treatment. (medscape.com)
Arteries have a great deal more smooth muscle within their walls than veins, thus their greater wall thickness. (onteenstoday.com)
Analysis of Viscoelastic Wall Properties in Ovine Arteries. (ncsu.edu)
This article on coronary artery anatomical variations will explore the anatomy and physiology of the heart, the arterial supply via the coronary arteries, the variations that can occur and the relevant clinical factors. (primalpictures.com)
Arteries also have thicker walls and have more nerves. (medlineplus.gov)
Blood in the arteries (arterial blood) differs from blood in the veins (venous blood) mainly in its content of dissolved gases (oxygen and carbon dioxide). (medlineplus.gov)
An arterial stick is done to get blood samples from arteries. (medlineplus.gov)
These techniques do not adequately address the time-dependent angular orientation of the arteries, whereby mispositioning of the imaged slice may cause disappearance of the lumen-wall interface altogether. (nih.gov)
Cerebral aneurysms form when the walls of the arteries in the brain become thin and weaken. (nih.gov)
Arterial bypass treats your narrowed arteries by creating a new pathway around a section of the artery that is blocked. (unmc.edu)
As you age, a sticky substance called plaque can build up in the walls of your arteries. (unmc.edu)
The model comprises 108 arterial segments, with 64 main arteries and 44 perforator arteries, with lumen radii ranging from 0.24 cm - axillary artery- to 0.018 cm - perforator arteries. (esaim-m2an.org)
As its name suggests, arterial tortuosity syndrome is characterized by blood vessel abnormalities, particularly abnormal twists and turns (tortuosity) of the blood vessels that carry blood from the heart to the rest of the body ( the arteries ). (nih.gov)
June 2022 - Peripheral arterial disease (PAD) simply is blockage in the arteries of your legs. (delraymedicalctr.com)

To evaluate the elasticity of the arterial wall more locally, it is necessary to noninvasively measure the local change in thickness of the arterial wall with amplitude of several micrometers. (elsevierpure.com)
From this small change in thickness, the systolic blood pressure, and the diastolic blood pressure, the average elastic modulus of the arterial wall is noninvasively evaluated. (elsevierpure.com)
The cine images are processed offline and a wall thickness measurement is produced. (nih.gov)
Normally, endothelial cells serve to maintain the integrity of the arterial wall, adapting to stress and injury by increasing wall thickness or altering the diameter to the lumen (channel cavity) of the vessel, increasing (vasodilatation) or decreasing (vasoconstriction) its size. (encyclopedia.com)

In this work, Su and colleagues developed the first-in-kind arterial wall-on-a-chip that mimics the structural interfaces and biology of human arterial wall. (ntu.edu.sg)

Peripheral arterial disease (PAD) is a potentially debilitating condition affecting more than 200 million people worldwide. (biomedcentral.com)
These findings suggested that LDL may be a cFAS carrier that distributes it to peripheral arterial tissue that is prone to atheroprogression 13 , and that cFAS may be an important marker for disease severity. (nature.com)
We hypothesized that higher serum cFAS is an indicator of CLTI, and that FAS localized to peripheral arterial tissue is associated with higher atherosclerotic plaque burden. (nature.com)
Dr. Ricotta specializes in minimally invasive endovascular therapy, endovascular robotic surgery, aortic and peripheral aneurysms, carotid/cerebrovascular disease, transcarotid artery revascularization, peripheral arterial disease (PAD)/limb salvage, venous disease, thoracic outlet syndrome, renal/mesenteric disease, dialysis access and pulmonary embolism care. (delraymedicalctr.com)
In peripheral arterial disease (PAD), long-term buildup of plaque along the artery walls causes reduced perfusion in peripheral circulation. (nih.gov)

Hence they have much thicker walls and more smooth muscles than do the pulmonary arterial vessels of equivalent caliber. (onteenstoday.com)
Proximal pulmonary arterial (PPA) wall disease can be involved in patients with persistent-PH after LSVR, affecting the right ventricular to pulmonary arterial (RV-PA) coupling. (uab.cat)
RV-PA coupling was estimated by the tricuspid annular plane systolic excursion to systolic pulmonary arterial pressure ratio. (uab.cat)
Despite normal PVR and DPG, Ipc-PH had a significant decrease in pulmonary arterial capacitance and RV-PA coupling impairment. (uab.cat)
Chapter: Acute pulmonary embolism and pulmonary Arterial Hypertension. (stanford.edu)
Genomics in Pulmonary Arterial Hypertension. (stanford.edu)
Modulating BMPRII Signaling in Pulmonary Arterial Hypertension The goals of this project are to use new technologies to modulate BMP signaling using High Throughput Screening of FDA approved drugs and bioactive compounds as well as microRNA mimics and antagomirs. (stanford.edu)
The goal of this project is to perform a phase II tolerability and efficacy study with Tacrolimus in patients with pulmonary arterial hypertension with dysfunctional BMPRII signaling. (stanford.edu)

SLC2A10 gene mutations that cause arterial tortuosity syndrome reduce or eliminate GLUT10 function. (nih.gov)

All arterial and venous vessels under basal conditions exhibit some degree of smooth muscle contraction that determines the diameter, and hence tone, of the vessel. (onteenstoday.com)
Which vessels have numerous smooth muscle cells in all layers of the wall? (onteenstoday.com)
The inclusion of wall visco-elasticity in the numerical model reduced the underdamped high-frequency oscillations obtained using a purely elastic tube law, especially in peripheral vessels, which was previously reported in this paper [Matthys et al. (imperial.ac.uk)
The modeling of blood flow in deformable vessels is governed by a well-known set of hyperbolic partial differential equations that accounts for mass and momentum conservation and a constitutive equation for the arterial wall. (esaim-m2an.org)
The smallest blood vessels in the brain, the capillaries, are subjected to an increased stress that causes damage to cells within and surrounding the capillary walls. (prohealth.com)

of the arterial walls due to plaque deposition. (nih.gov)
This plaque buildup in-turn narrows the artery walls causing poor circulation throughout the legs. (delraymedicalctr.com)

The elastic modulus of the arterial wall depends upon the arterial inner pressure because of the hysteresis property between the inner pressure and the strain of the artery. (elsevierpure.com)

This allows early identification of loss of elasticity, which is important because premature arterial stiffening is an apparent marker for the early onset of cardiovascular disease. (medscape.com)

An arterial dissection is a tear within the wall of an artery, which allows blood to separate the wall layers. (wikipedia.org)
Vein wall dissection: a rare puncture-related complication of brachiocephalic fistula. (wikipedia.org)
Rupture of an aneurysm or sudden tearing (dissection) of the layers in an arterial wall can result in massive loss of blood from the circulatory system. (nih.gov)
Fibromuscular dysplasia also weakens the vessel wall which predisposes to dissection. (radiopaedia.org)

The Center without Walls should encompass research that will move promising ligands through in vitro and in vivo optimization to first-in-human studies. (nih.gov)

In the 1980s, Libby, then an assistant professor of medicine at Tufts University School of Medicine, was the first to discover that arterial wall cells-called endothelial cells-can produce and respond to small proteins that promote inflammation in cardiovascular disease. (nih.gov)
The AVALON-AWC study was based on the hypothesis that because the lipid-lowering agent atorvastatin and the calcium-channel blocker amlodipine have each been shown to have beneficial effects on the endothelium in vitro, they may have a greater effect on endothelial function and arterial compliance when administered together. (medscape.com)

The infection weakens the artery wall, causing a bulging aneurysm to form. (nih.gov)
An aneurysm is a balloon-like bulge of an artery wall. (mayfieldclinic.com)

However, vessel wall calcifications, frequently present in diabetic and elderly patients, diminish its clinical utility (1). (biomedcentral.com)
Unlike CTA, vessel wall calcifications are invisible with MRA and do not impair diagnostic accuracy. (biomedcentral.com)
However, the invisibility of calcifications is also a substantial deficiency given that the distribution and severity of vessel wall calcifications have clinical implications for interventional treatment strategy (3), and the presence of vessel wall calcifications contributes additional risk for morbidity and mortality. (biomedcentral.com)
In order to overcome this significant limitation, we have implemented a novel "neutral contrast 3D MRI" (NCMRI) technique that detects vessel wall calcifications with CT-like spatial resolution over large fields of view. (biomedcentral.com)
Neutral contrast MRI provides, for the first time, an efficient, volumetric approach for the detection of peripheral vessel wall calcifications by MRI. (biomedcentral.com)
The purpose of this study was to characterize the impact of intracranial vessel wall MR imaging on the etiologic classification of ischemic stroke. (ajnr.org)
This was a single-center, retrospective study of 205 consecutive patients who were referred for vessel wall MR imaging to clarify the etiology of an ischemic stroke or TIA. (ajnr.org)
An expert panel classified stroke etiology before and after incorporating vessel wall MR imaging results using a modified Trial of Org 10172 in Acute Stroke Treatment system. (ajnr.org)
We measured the proportion of patients with an altered etiologic classification after vessel wall MR imaging. (ajnr.org)
Vessel wall MR imaging altered the etiologic classification in 55% (112/205) of patients. (ajnr.org)
The time between symptom onset and vessel wall MR imaging was not a predictor of impact. (ajnr.org)
When vessel wall MR imaging is performed to clarify the etiology of a stroke or TIA, it frequently alters the etiologic classification. (ajnr.org)
[ 99 ] This key diagnostic feature is believed to represent vessel wall edema. (medscape.com)
Any layer of the vessel wall may be affected: intima, media or adventitia. (radiopaedia.org)

Recent discoveries have suggested that MFG-E8 associated interventions are novel approaches for the retardation of the enhanced rates of VSMC proliferation and EC apoptosis that accompany arterial wall inflammation and remodeling during aging and age-associated arterial disease. (johnshopkins.edu)
In addition, increased inflammation in arterial wall is evident. (nih.gov)

Patients with persistent PH after successful LSVR have PPA wall disease and RV-PA coupling impairment beyond the hemodynamic phenotype. (uab.cat)
Patients with PAD and arterial wall calcifications by CTA were imaged at 1.5 Tesla. (biomedcentral.com)
The method also provides more precise wall measurements and a more distinct difference between healthy subjects and patients. (nih.gov)
Initially, patients may experience intermittent claudication which is an exercise-induced, crampy, heavy feeling in the muscles of the calf, and thigh, or disease in the arterial tree. (encyclopedia.com)
In arterial plaques that had been surgically removed from patients, the researchers saw an inflammatory response to SARS-CoV-2 infection like that seen in the cultured cells. (nih.gov)
HCTs were performed on 19 adult patients with KS and/or NMD (age 22-73 years, forced expiratory volume in 1 s (FEV 1 ) 0.76, forced vital capacity (FVC) 0.92, SaO 2 95%, partial pressure of arterial CO 2 (PaCO 2 ) 5.7 kPa) who were at risk for nocturnal hypoventilation. (bmj.com)
Non-invasive evaluation of the arterial wall properties in female patients with systemic. (usp.br)

The findings suggest that SARS-CoV-2 may increase the risk of heart attacks and stroke by infecting artery wall tissue, including associated macrophages. (nih.gov)
CEC is shorthand for the ability of arterial macrophages to release excess cholesterol, preventing it from accumulating on artery walls. (asbmb.org)

They found more viral RNA in the arterial walls than in the surrounding fat tissue. (nih.gov)
Arterial tortuosity syndrome is a disorder that affects connective tissue. (nih.gov)
Features of arterial tortuosity syndrome outside the circulatory system are caused by abnormal connective tissue in other parts of the body. (nih.gov)

Occasionally, cerebral aneurysms may be present from birth, usually resulting from an abnormality in an artery wall. (nih.gov)

It is not known how dietary fats might directly affect arterial LDL-CE uptake and whether SU is involved. (jci.org)

The outcome is arterial stenoses. (radiopaedia.org)

Additional studies have shown that MFG-E8 is also an element of the arterial inflammatory signaling network. (johnshopkins.edu)

Capillary walls weaken with UV exposure, so wearing a good sunscreen can potentially prevent the development of some broken capillaries," says Dr. Akhavan. (onteenstoday.com)

1 It was recommended that assessment should include pulse oximetry, with arterial blood gas analysis being preferred if hypercapnia is suspected. (bmj.com)

Arterial imaging with CT angiography, MR angiography and digital subtraction angiography (DSA) may be used to visualize the lesions in fibromuscular dysplasia. (radiopaedia.org)

Existing techniques suffer from image degradation due to aperiodic intrinsic cardiac, chest wall motions, or other bulk motion that often cause image blur and reduced wall sharpness. (nih.gov)

As a disease family, arterial dissections share common features, including shared genetic risk variants, and commonly perturbed molecular pathways. (wikipedia.org)

Led by Drs. Vinicio de Jesus Perez, Associate Professor in Pulmonary, Allergy and Critical Care Medicine and Rachel Hopper, MD, Clinical Associate Professor in Pediatric Cardiology, please join us for PH Grand Rounds featuring the Wall Center at Stanford-Latin America (LATAM) Initiative on September 18 and 19, 2023 (in-person or zoom). (stanford.edu)

This formulation allows for inclusion of an elastic response as well as an appropriate creep function allowing for the description of the viscoelastic deformation of the arterial wall. (ncsu.edu)

Wall calcifications (arrows) in the distal left common femoral artery (CFA) are comparably shown by the two modalities. (biomedcentral.com)
Brown pigment is present in the wall of the artery (arrows). (nih.gov)

Objective -To evaluate the use of hoof wall surface temperature (HWST) as an indirect indicator of digital perfusion and to describe HWST patterns during the prodromal and acute phases of carbohydrate-induced laminitis in horses. (avma.org)

The underlying pathology is a fibrous or fibromuscular thickening of the arterial wall. (radiopaedia.org)

The prime function of the arterial smooth muscle cell (SMC) in adult individuals is to contract and relax, thereby regulating blood flow to target tissues. (onteenstoday.com)
Results of this study demonstrate that incorporation of a viscoelastic wall model allows more physiologic prediction of arterial blood pressure and vessel deformation, which often is overestimated with the simple elastic wall models, while blood flow does not differ significantly between models. (ncsu.edu)

As a result of these complications, arterial tortuosity syndrome is often fatal in childhood, although some individuals with mild cases of the disorder live into adulthood. (nih.gov)

Arterial blood gas measurements were made before and at the end of the hypoxic challenge. (bmj.com)

Hoof wall surface temperature significantly decreased during arterial occlusion and increased during reperfusion. (avma.org)

Arterial dissections become life-threatening when growth of the false lumen prevents perfusion of the true lumen and the related end organs. (wikipedia.org)

Anatomy49

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