Arterial ventricular outflow obstruction. Medical search. Frequent questions

This video shows the repair of a newborn with transposition of the great arteries and ventricular septal defect (VSD) by means of arterial switch and VSD closure. (medscape.com)
Switch ventricular septal defect (VSD hypoplastic right arch). (medscape.com)
The primary anatomic subtypes are (1) transposition of the great arteries with intact ventricular septum, (2) transposition of the great arteries with ventricular septal defect , (3) transposition of the great arteries with ventricular septal defect and left ventricular outflow tract obstruction, and (4) transposition of the great arteries with ventricular septal defect and pulmonary vascular obstructive disease. (medscape.com)
It is characterized by a large ventricular septal defect (VSD), right ventricular outflow tract obstruction (Pulmonic stenosis), right ventricular hypertrophy and overriding of aorta. (ispub.com)
Tetralogy of Fallot consists of 4 features: a large ventricular septal defect, right ventricular outflow tract obstruction and pulmonic valve stenosis, right ventricular hypertrophy, and over-riding of the aorta. (msdmanuals.com)
Ventricular Septal Defect (VSD) A ventricular septal defect (VSD) is an opening in the interventricular septum, causing a shunt between ventricles. (msdmanuals.com)
The ventricular septal defect in tetralogy of Fallot is often described as a malalignment type, since the conal septum is displaced anteriorly. (msdmanuals.com)
By contrast, the papillary muscles of the RV are comparatively small, numerous, unbalanced, and arise from both ventricular septal and free walls. (nih.gov)
For patients with TGA, ventricular septal defect (VSD) and left ventricular outflow tract obstruction/pulmonary stenosis (PS), the Rastelli operation, REV procedure and modified Nikaidoh procedure have been developed, and these procedures were observed favorable with long-term result and survival rate 4 , 5) . (e-cep.org)
Prenatal detection of membranous ventricular septal aneurysm requires clinical, morphological and functional evaluation, as the spectrum of a congenital ventricular out-pouching is vast and complex. (fortuneonline.org)
Congenital membranous ventricular septal aneurysm (VSA) is a rare cardiac malformation that counts for less than 0.3 % of all congenital heart diseases with an equal distribution between the sexes [1,2]. (fortuneonline.org)
Based on fetal echocardiography distinguishment of the different conditions causing a membranous ventricular septal protrusion is often challenging, in particular in the setting of various clinical presentations and prenatal imaging [3,5,6]. (fortuneonline.org)
We describe the first case of a prenatal detection of a congenital membranous VSA bulging from the left ventricle towards the right atrium, associated with a tricuspid atresia with concordant ventriculo-arterial connection and a ventricular septal defect. (fortuneonline.org)
Ventricular morphology was mainly defined by a dominant left ventricle (LV) and a rudimentary right ventricle (RV) with a large unrestrictive ventricular septal defect (VSD) (4.7 mm). (fortuneonline.org)
Combined atrial and arterial switch procedure for congenital corrected transposition with ventricular septal defect. (bmj.com)
Associated anomalies are common and include atrial septal defect, ventricular septal defect, patent ductus arteriosus, pulmonic valve stenosis, and transposition of the great arteries. (merckmanuals.com)

This displaced septum protrudes into the pulmonary outflow tract, often resulting in obstruction and hypoplasia of the downstream structures, including the pulmonary valve, main pulmonary artery, and branch pulmonary arteries. (msdmanuals.com)
Morphologically it is characterized by an abnormal localized protrusion or "out-pouching" of the membranous part of the ventricular septum with or without a paradoxical systolic expansion that nearly always stays intracardiac [3,4]. (fortuneonline.org)
However, as congenital aneurysms of the membranous part of the ventricular septum have been reported to be associated with other cardiac anomalies, such as outflow tract obstructions, coarctation of the aorta, or even with chromosomal abnormalities or genetic syndromes, hemodynamic disturbance may occur in the postnatal period [9-12]. (fortuneonline.org)
It is called a double outlet RV if more than 50% of the aorta goes over the ventricular septum. (medical-definitions.net)

Oxygenated pulmonary venous blood returns to the left atrium and left ventricle but is recirculated to the pulmonary vascular bed via the abnormal pulmonary arterial connection to the left ventricle. (medscape.com)
The procedure is performed via the arterial route or the venous route depending upon the heart condition, anatomical considerations and the preference of your doctor. (ntccardiology.com)
BACKGROUND: Veno-arterial-venous extracorporeal membrane oxygenation (V-AV ECMO) is a less commonly used configuration of ECMO. (bvsalud.org)
Chapters are devoted to specific conditions and feature detailed descriptions of how to perform a variety of appropriate reparative surgical techniques involving complex anatomy, reoperative surgery, and unique techniques to this speciality, enabling the reader to develop a deep understanding of how to successfully resolve situations such as left ventricular outflow tract obstruction, anomalous pulmonary venous return, and anomalous origin of the coronary arteries. (nshealth.ca)
INTRODUCTION - The physical examination of the cardiovascular system includes auscultation and palpation of the heart, as well as assessment of the arterial and venous pulses. (medilib.ir)
See "Examination of the precordial pulsation" and "Examination of the arterial pulse" and "Examination of the jugular venous pulse" . (medilib.ir)

This right ventricular angiogram shows a patient with transposition of the great arteries. (medscape.com)
Arterial switch operation (ASO) or arterial switch, is an open heart surgical procedure used to correct dextro-transposition of the great arteries (d-TGA). (wikipedia.org)
Transposition of the great arteries (TGA) is a congenital heart anomaly with 0.45 cases per 1,000 live births, and the arterial switch operation (ASO) has become the treatment of choice for surgical correction of complete TGA. (e-cep.org)
Peripheral Endothelial Function After Arterial Switch Operation for D-looped Transposition of the Great Arteries. (rchsd.org)

An estimated 2-9% of patients with tetralogy of Fallot have coronary arterial anomalies, which may affect the timing of or approach to surgical repair. (medscape.com)
Prenatal detection of critical cardiac outflow tract anomalies remains suboptimal despite revised obstetrical imaging guidelines. (rchsd.org)
Background: Single-stage repair of complex cardiac anomalies with arch obstruction can be very risky in neonates with extreme prematurity, small weight, severe extra-cardiac problems or sepsis. (chss.org)

Pulmonic Stenosis Pulmonic stenosis (PS) is narrowing of the pulmonary outflow tract causing obstruction of blood flow from the right ventricle to the pulmonary artery during systole. (merckmanuals.com)

Trans-thoracic echocardiography revealed situs solitus levocardia with atrioventricular and ventricular arterial concordance. (blogspot.com)
Color flow imaging confirmed the diagnosis of tricuspid atresia with concordant ventriculo-arterial connection by demonstrating the lack of a blood flow across the tricuspid valve and a patent normal-sized left atrioventricular (mitral) valve without regurgitation. (fortuneonline.org)
Coronary sinus obstruction after atrioventricular canal defect repair. (rchsd.org)

a severe obstruction causes a right-to-left shunt, resulting in low systemic arterial saturation (cyanosis) that is unresponsive to supplemental oxygen. (msdmanuals.com)
2 Even in patients with Eisenmenger syndrome - the most severe form of PAH - bosentan decreased the mean systemic arterial pressure, which may have slowed the progression to heart failure by reducing the strain on the right and left ventricles. (pulmonologyadvisor.com)
In that case, a systemic arterial to pulmonary artery shunt may be the first step in surgery to improve blood flow to the lungs. (medical-definitions.net)

Patients with aortic valve disease, left ventricular outflow tract obstruction and intracardiac shunt were excluded from the study. (unesp.br)
Use no consult sildenafil citrate in patients with left ventricular outflow obstruction eg, aortic stenosis. (centrum-ubezpieczen.pl)
Obstruction of the left ventricular outflow tract (including severe aortic stenosis). (pharmru.com)
Cardiac diagnosis was interrupted aortic arch, VSD, very narrow LV outflow tract. (chss.org)

The changes of arterial pressure promoted by bolus injection of 50 mg phenylephrine (PHE) were studied in 20 atropinized patients (5 normal subjects, 13 patients with mitral valve disease, 1 patient with essential arterial hypertension and 1 patient with hypertrophic cardiomyopathy) submitted to routine catheterism. (unesp.br)
Pulmonary arterial hypertension (PAH), documented in a significant portion of hypertrophic cardiomyopathy (HCM) patients, has been shown to adversely impact prognosis. (cpxinternational.com)

Hypothetically, a pathological obstruction of the LVOT of a different etiology would result in a comparable hemodynamic instability, which would be refractory to inotrope therapy, and may be detectable through echocardiography. (biomedcentral.com)
Transesophageal echocardiography (TEE) showed a massive, dynamic LVOT obstruction. (biomedcentral.com)
Combining cardiopulmonary exercise test (CPET) with echocardiography, we aimed to evaluate the presence of exercise induced pulmonary arterial hypertension (EiPAH), its role in functional limitation and its prognostic significance in a cohort of patients with obstructive and non-obstructive HCM. (cpxinternational.com)
1 In the absence of quality evidence, Dimopoulos and the CHAMPION Steering Committee (Congenital Heart Disease and Pulmonary Arterial Hypertension: Improving Outcomes Through Education and Research Networks) compiled evidence in a 25-study review and surveyed PH and congenital heart disease experts on the use of echocardiography for PH screening in patients with adult congenital heart disease . (pulmonologyadvisor.com)

Total repair of tetralogy of Fallot usually includes a VSD patch and an enlarging RV outflow tract patch. (medical-definitions.net)
Most adults with tetralogy of Fallot have had surgery, usually to fix the RV outflow and close the VSD. (medical-definitions.net)

We present the case of a rare thrombus formation attached to the mitral valve under procoagulant therapy, massive transfusion and extracorporeal membrane oxygenation (ECMO) therapy despite continued anticoagulation, which resulted in a unique dynamic obstruction of the LVOT similar to a SAM phenomenon. (biomedcentral.com)
Cerebral Infarction During Cervical Veno-Arterial Extracorporeal Membrane Oxygenation in Children: Can it be Predicted? (wspchs.org)

Severe concentric hypertrophy was observed without outflow or intra-cavity obstruction (Figure 1c). (blogspot.com)
The thrombotic structures situated at the mitral valve caused a severe systolic obstruction of the LVOT comparable to the so-called SAM [systolic anterior motion] phenomenon [ 2 ]. (biomedcentral.com)
Surgery for infants with a hypoplastic systemic ventricle and severe outflow obstruction: early results with a modified Norwood procedure. (bmj.com)
However, since the concentration of the latter is markedly reduced, the absolute quantity of reduced hemoglobin may still be small, and therefore patients with severe anemia and even marked arterial desaturation do not display cyanosis. (medenosrce.net)

In the event of sepsis or delayed diagnosis, a combination of pulmonary artery banding (PAB) and shunt construction may be used to increase the left ventricular mass sufficiently to make an arterial switch possible later in infancy. (wikipedia.org)
Any previous arterial-pulmonary artery shunt is also taken down. (medical-definitions.net)
iv) Central cyanosis due to right-to-left shunt, reduced oxygen concentration in the arterial blood, or pulmonary vascular disease. (socialsecurityprofessionals.com)

A second hypothesis suggests that the principal high-frequency elements of S1 are related to movement and acceleration of blood in early systole, and are influenced by the peak rate of rise of left ventricular (LV) systolic pressure (dP/dt), which is a measure of contractility and ejection of blood into the root of the aorta [ 14 ]. (medilib.ir)
Results: Following redo sternotomy and CPB using dual arterial and bicaval cannulation, dissection or arch, descending aorta and PA branches to hilum was performed. (chss.org)

The pulse wave patterns of patients with oHCM were consistent with the turbulent blood flow and heart rate variability associated with obstruction of the left ventricular outflow tract (LVOT) characteristic of oHCM. (globenewswire.com)
Obstructive HCM (oHCM) is a form of HCM characterized by a dynamic obstruction of the LVOT that results in abnormalities in arterial blood flow. (globenewswire.com)
In cases of hypertrophic obstructive cardiomyopathy (HOCM), the systolic anterior motion of the mitral valve apparatus results in an obstruction of the left ventricular outflow tract (LVOT), which is known as the SAM [systolic anterior motion] phenomenon. (biomedcentral.com)
We observed a severely impaired left ventricular function due to a combination of a thrombotic LVOT obstruction and distinctive mitral regurgitation in a 56-year-old Caucasian, female patient after massive transfusion with aggressive procoagulant therapy. (biomedcentral.com)
Massive transfusion with aggressive procoagulant therapy resulted in mitral valve leaflet thrombosis with dynamic, predominantly systolic LVOT obstruction, comparable to the SAM phenomenon. (biomedcentral.com)
The known common causes of left ventricular outflow tract (LVOT) obstruction include hypertrophic obstructive cardiomyopathy (HOCM), dehydration, sepsis, cardiac surgical treatment after valve repair, and Takotsubo cardiomyopathy [ 1 ]. (biomedcentral.com)
In the case reported here, the LVOT obstruction was caused by thrombotic formations. (biomedcentral.com)
In this condition, the anterior leaflet (cusp) moves towards the LVOT and obstructs the outflow tract. (biomedcentral.com)
Left-ventricular outflow tract (LVOT) velocities, trans-tricuspid gradient, and cardiopulmonary variables were continuously measured. (cpxinternational.com)
0.0001) and baseline LVOT obstruction (p = 0.028) were significantly associated with EiPAH. (cpxinternational.com)

Preoperative arterial blood gas analysis revealed desaturation with a Sao2 of 86% and Pao2 of 55 mmHg. (ispub.com)
Level of arterial desaturation is related to severity of the RV outflow tract obstruction. (msdmanuals.com)

Ventricular arrhythmias can start at the edge of the VSD or the outflow tract patch, and they tend to happen more often as the RV gets bigger. (medical-definitions.net)

Minute Stroke Distance Is a More Reproducible Measurement Than Cardiac Output in the Assessment of Fetal Ventricular Systolic Function. (rchsd.org)

citation needed] As with any procedure requiring general anaesthesia, arterial switch recipients will need to fast for several hours prior to the surgery to avoid the risk of aspiration of vomitus during the induction of anesthesia. (wikipedia.org)
2. There are many anatomic considerations suggesting the morphologically left ventricle (LV) may well be a better systemic pump than the morphologically right ventricle (RV) which, if true, would favor the arterial switch procedure as opposed to an atrial switch operation: (1) The LV consists almost entirely of the sinus or pumping portion, and has only a minimal distal infundibular (conal) component. (nih.gov)
For patients undergoing the Jatene arterial switch procedure, the presence of an intramural coronary artery course in patients with D-TGA may prohibit arterial repair. (medscape.com)

Dynamic obstruction of the left-ventricular outflow tract is a rare condition. (biomedcentral.com)

HCM is a myocardial disease characterized by hypertrophy of the left ventricle which is not secondary to congenital heart disease or arterial hypertension. (czytelniamedyczna.pl)
Despite the frequency with which pulmonary arterial hypertension (PAH) occurs in patients with adult congenital heart disease, there are no guidelines directing clinicians on echocardiographic screening for pulmonary hypertension (PH). (pulmonologyadvisor.com)

The most common anomaly (4% of patients) is the origin of the left anterior descending (LAD) coronary artery from the right coronary artery (RCA), which then courses across the pulmonary outflow tract. (medscape.com)
This is important because when fixing the RV outflow obstruction, surgery must be careful not to hurt the coronary artery. (medical-definitions.net)
If the blood supply to the heart muscle continues to decrease as a result of increasing obstruction of a coronary artery, a myocardial infarction, or heart attack, may occur. (drnishantchandel.com)

Sildenafil is a medication used in the management and treatment of erectile dysfunction and pulmonary arterial hypertension. (nih.gov)
Knowledge therein is critical for appropriate healthcare team management of patients with erectile dysfunction, pulmonary arterial hypertension, and/or related conditions. (nih.gov)
Explain the mechanism of action of sildenafil in the treatment of erectile dysfunction and pulmonary arterial hypertension. (nih.gov)
Outline appropriate monitoring of sildenafil therapy in erectile dysfunction and pulmonary arterial hypertension. (nih.gov)
Sildenafilsold as the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. (centrum-ubezpieczen.pl)
Tadalafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). (cyno.co.in)

There may also be pulmonary valve stenosis, usually caused by an RV outflow hypoplasia or a pulmonary valve with two flaps instead of one. (medical-definitions.net)

These palliative therapies were followed by physiological procedures (atrial switch operation) and anatomic repair (arterial switch operation) (see the videos below). (medscape.com)

There were no adverse events associated with intravenous PHE injection in any patient, in accordance with the general view that bolus injection of PHE is a safe and practical maneuver to promote arterial hypertension. (unesp.br)
Sildenafil also has FDA approval for the treatment of World Health Organization Group I pulmonary hypertension (also known as pulmonary arterial hypertension (PAH)) in adults to improve exercise tolerance and delay clinical worsening. (nih.gov)
In patients with vasoactive pulmonary arterial hypertension, vasodilation of the pulmonary artery leads to reduced resistance to blood flow, with subsequent reductions in mean pulmonary arterial pressure. (nih.gov)
Arterial hypertension (in both monotherapy and in combination with other antihypertensive agents). (pharmru.com)
Tadalafil tablets are a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve exercise ability. (nih.gov)

Frequently, the conus branch of the RCA is large and supplies a significant portion of the right ventricular infundibular muscle. (medscape.com)
Infundibular stenosis blocks the outflow of blood from the RV. (medical-definitions.net)

Disorders of the veins or arteries (for example, obstruction, rupture, or aneurysm) may cause impairments of the lower extremities (peripheral vascular disease), the central nervous system, the eyes, the kidneys, and other organs. (socialsecurityprofessionals.com)

Surgical repair of pulmonary outflow obstruction often involves patching the right ventricular outflow tract and resecting the obstructing right ventricular muscle. (medscape.com)
In patients with symptomatic left ventricular outflow tract obstruction refractory to medical therapy a surgical myectomy should be considered. (czytelniamedyczna.pl)

thus patients with marked polycythemia tend to be cyanotic at higher levels of arterial oxygen saturation than patients with normal hematocrit values. (medenosrce.net)
Decreased arterial oxygen saturation results from a marked reduction in the oxygen tension in the arterial blood. (medenosrce.net)
Hb Kansas) causes lowered arterial oxygen saturation and resultant central cyanosis (Chap. 306). (medenosrce.net)

If cardiac tamponade Tamponade Pericardial effusion, usually of rapid onset, exceeding ventricular filling pressures and causing collapse of the heart with a markedly reduced cardiac output. (lecturio.com)
iii) Syncope, or near syncope, due to inadequate cerebral perfusion from any cardiac cause, such as obstruction of flow or disturbance in rhythm or conduction resulting in inadequate cardiac output. (socialsecurityprofessionals.com)

Peripheral cyanosis is due to a slowing of blood flow to an area and abnormally great extraction of oxygen from normally saturated arterial blood. (medenosrce.net)

However, at 5000 m (16,000 ft) the oxygen tensions in atmospheric air and alveolar air are about 85 and 50 mmHg, respectively, and the oxygen dissociation curve shows that the arterial blood is only about 75 percent saturated. (medenosrce.net)

Pathophysiology depends on the degree of right ventricular outflow obstruction. (msdmanuals.com)

Using an investigational wrist-worn photoplethysmography (PPG) digital health device, arterial pulse wave patterns of oHCM patients were shown to be distinct from those of individuals without oHCM. (globenewswire.com)
Using an investigational wearable PPG device developed by Wavelet Health, arterial pulse wave data were collected at baseline from 19 oHCM patients enrolled in MyoKardia's PIONEER-HCM clinical trial. (globenewswire.com)
Transition to durable left ventricular assist device was performed in 3% (2/64) of patients, while 3% (2/64) underwent heart transplantation. (bvsalud.org)
Arterial and half-turned truncal switch operations were performed in 25 and 3 patients (Group III), respectively. (e-cep.org)
Subsequently, a study by Sharma et al documented the use of ERAS in emergency settings in patients with perforation and intestinal obstruction and found it to be safe and feasible. (medscape.com)
Do radionuclide and echocardiographic techniques give a universal cut off value for left ventricular ejection fraction that can be used to select patients for treatment with ACE inhibitors after myocardial infarction? (bmj.com)

The flow in this vessel, which has its distribution over the left ventricular myocardium, is retrograde to the main pulmonary artery. (medscape.com)

Long-term outcomes in adults with prior arterial switch operation (ASO) have not yet been well defined. (techscience.com)

Takotsubo Cardiomyopathy and Left Ventricular Outflow Tract Obstruction. (ottawaheart.ca)

The left radial artery was cannulated for direct arterial pressure monitoring and ABG analysis intra and post operatively. (ispub.com)

A blood transfusion is necessary for the arterial switch because the HLM needs its "circulation" filled with blood and an infant does not have enough blood on their own to do this (in most cases, an adult would not require blood transfusion). (wikipedia.org)
HCM is typically diagnosed by echocardiogram to visually identify the thickening of the heart wall, anatomical blood flow obstruction and heart valve movement. (globenewswire.com)
In the central type, there is arterial blood unsaturation or an abnormal hemoglobin derivative, and the mucous membranes and skin are both affected. (medenosrce.net)

Anatomy11

Diseases29

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Phenomena and Processes3

Health Care3

Septal16

Septum4

Venous6

Transposition4

Anomalies3

Pulmonic1

Atrioventricular3

Systemic arterial3

Aortic4

Hypertrophic cardiomyopathy2

Echocardiography4

Tetralogy of Fal2

Extracorporeal membrane ox2

Severe4

Shunt3

Aorta2

LVOT10

Desaturation2

Arrhythmias1

Systolic function1

Procedure3

Dynamic obstruction1

Congenital heart d2

Coronary artery3

Erectile Dysfunction6

Hypoplasia1

Anatomic1

Hypertension5

Infundibular2

Aneurysm1

Surgical2

Saturation3

Cardiac output2

Cyanosis1

Oxygen1

Pathophysiology1

Patients6

Main pulmon1

Switch operation1

Cardiomyopathy1

Post-operatively1

Blood3