Arterial conclusions models cardiovascular. Medical search. Frequent questions

In hyperactive platelets from patients with peripheral arterial disease we could not detect increased P2 receptor expression as compared to healthy controls. (avhandlingar.se)
Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels, and they include coronary heart disease, cerebrovascular disease, peripheral arterial disease, rheumatic heart disease, congenital heart disease, deep vein thrombosis and pulmonary embolism [ 1 ]. (biomedres.info)
In line with the ageing population, the prevalence of coronary artery disease (CAD), lower extremity peripheral arterial disease (PAD), supra-aortic arterial disease (SAD) and renal stenosis (RAS) is increasing. (who.int)

Fisetin, a flavonoid phytonutrient present in almost all kinds of fruits and vegetables, has recently emerged as a powerful antioxidant for health promotion [ 9 , 10 ] and exerts multiple protective effects in different oxidative stress-related conditions in human, such as degenerative diseases (e.g., vascular dementia), cancer, diabetes, and cardiovascular diseases [ 11 - 14 ]. (hindawi.com)
The outcome events were cardiovascular diseases (CVDs), while the independent variable was total daily physical activity. (biomedcentral.com)
Diseases such as diabetes, atherosclerosis, cardiomyopathies, and arterial hypertension result in functional and morphologic microvascular alterations, which may precede clinical signs and symptoms. (biomedcentral.com)
Objectives The hypothesis of the study was that if the gut microbiota is involved in the development of atherosclerotic cardiovascular and cerebrovascular diseases (CVDs), total colectomy may reduce the long-term risk of CVDs. (bmj.com)
Primary and secondary outcome measures The primary outcome was the first occurring CVD event in any of the seven diagnostic domains (hypertensive disorders, acute ischaemic heart diseases, chronic ischaemic heart disease, cardiac arrhythmias, heart failure, cerebrovascular diseases and other arterial diseases) and the secondary outcomes were the first occurring event within each of these domains. (bmj.com)
The major strength of the study is based on the availability of information in the entire Danish Patient Register from 1996 to 2014, which allows historical prospective assessment of the risk of new occurrences of cardiovascular and cerebrovascular diseases (CVDs) during long-term, essentially complete follow-up in patients after colectomy by comparison with matched patients that had undergone other types of surgery. (bmj.com)
Chronic auto-inflammatory diseases are associated with an increased risk of arterial and venous cardiovascular diseases (CVD). (ecco-ibd.eu)
Cardiovascular diseases (CVDs) were the number one cause of death in Iran. (biomedcentral.com)
Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels, including coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other conditions. (biomedcentral.com)
BACKGROUND: Cardiovascular diseases are the number one killer in the developed countries, accounting for approximately half of all deaths, with the leading causes being myocardial infarction and ischaemic stroke. (who.int)
These include neurodegenerative diseases, cardiovascular and cerebrovascular diseases, and metabolic-related diseases, among others. (nutritionaloutlook.com)
Type 2 diabetes, which is the most common form, can be life threatening due to its complications, particularly, cardiovascular diseases. (who.int)
In the African Region, efforts made to create an environment that enhances the fight against diabetes include adoption of resolutions AFR/RC50/R4 on noncommunicable diseases: strategy for the African Region, in 2000, and AFR/RC55/R4: cardiovascular diseases in the African Region, in 2005. (who.int)
[ 5 , 7 ] Although the underlying mechanisms are complex, the chronic inflammatory state and microbial burden in people with periodontal disease may predispose them to cardiovascular diseases in ways proposed for other infections. (medscape.com)
The study provides baseline data for monitoring and managing cardiovascular diseases in the country. (who.int)
Despite decreases in mortality rates due estimate of myocardial infarction inci- of the population census from the Sta- to cardiovascular diseases in most de- dence has been reported for the whole tistical Center of Iran in 2011 were used. (who.int)
Although cardiovascular diseases ducted to determine the incidence rate cal variables as percentages. (who.int)

We hypothesized that higher BP, particularly systolic pressure, and increased arterial stiffness (i.e., pulse pressure), would be associated with lower cognitive function. (nih.gov)
The association between increased arterial stiffness and left ventricular diastolic dysfunction (LVDD) may be influenced by left ventricular performance. (medsci.org)
Obstructive sleep apnea (OSA) is associated with increased arterial stiffness, a cumulative indicator of arterial health. (acc.org)

Among middle-aged and older diverse Hispanics/Latinos, we found modest but consistent associations between indicators of arterial stiffness, and compromised blood flow and lower cognitive function. (nih.gov)
To investigate the role of vascular function, we assessed levels of the augmentation index (a correlate of arterial stiffness) after short-term exposure to welding -derived fine particulate matter (PM2.5). (cdc.gov)
Although there were several parameters using in the assessment of arterial stiffness, the gold standard of non-invasive arterial stiffness measurement is carotid-femoral pulse wave velocity [ 3 ]. (medsci.org)
Inflammation plays a pivotal role in hypertension, as a large number of studies have already demonstrated that systemic inflammation levels of patients with hypertension are elevated, which are closely associated with arterial stiffness ( 4 ). (frontiersin.org)
A meta-analysis of the available literature investigating the effect of CPAP on arterial stiffness in patients with OSA was conducted. (acc.org)
Fifteen articles (n = 615 patients) assessing indices of arterial stiffness were identified. (acc.org)
Five different meta-analyses were performed assessing: a) all indices of arterial stiffness, b) augmentation index (AIx), c) all pulse wave velocities (PWV), d) brachial-ankle PWV and e) carotid-femoral PWV. (acc.org)
Neither the proportion of compliant patients nor the duration of CPAP use altered the effect of arterial stiffness reduction after CPAP treatment. (acc.org)
In conclusion, this study showed significant improvements in all indices of arterial stiffness after CPAP treatment in patients with OSA. (acc.org)
As clinical use of arterial stiffness is growing in popularity, the efficacy of this useful tool in assessing cardiovascular risk reduction among patients with OSA treated with CPAP needs to be further explored. (acc.org)
6 Their meta-analysis revealing significant improvement in all indices of arterial stiffness after continuous positive airway pressure (CPAP) treatment, underscores the importance of early vascular dysfunction assessment in OSA. (acc.org)
It is well known that endothelial dysfunction and arterial stiffness mark the onset of atherosclerosis and are associated with adverse CVD events. (acc.org)
7 Although various measures of arterial stiffness have been proposed as CVD risk markers, they are not yet accepted into clinical practice. (acc.org)
While multiple studies have validated arterial stiffness as a CVD risk marker in wide range of patient populations, 7 large community-based outcome studies are still needed to clarify the position of arterial stiffness assessment in clinical practice. (acc.org)
study were middle-aged men with at least moderate OSA, will their findings hold true for women, or particular racial/ethnic groups, or those with severe OSA and extreme arterial stiffness severity scores? (acc.org)

In this review, we present different strategies yielding encouraging results at the population level, from childhood until old age, that aim to protect against the challenges facing the scientific community when combating cardiovascular disease. (revespcardiol.org)

Angiotensin II (AngII) stimulates oxidative stress in VSMC, inducing VSMC proliferation and migration, which is a critical factor in both developments of hypertension and angioplasty-induced arterial restenosis. (hindawi.com)
Hypertension is characterized not only by a metabolic syndrome that includes obesity and insulin resistance, but also by increases in left-ventricular mass (LVM), reduced arterial compliance and altered renal function. (scienceopen.com)
This investigation has examined a possible role for the renin-angiotensin system as well as body mass and insulin values in mediating these cardiovascular and renal aspects of the hypertension syndrome. (scienceopen.com)
It reduces the arterial pressure of the Deoxycorticosterone acetate-induced hypertension model in rats. (immune-system-research.com)
Besides, it can reduce arterial pressure in a rat model of hypertension and can play roles in cardiovascular disease research. (immune-system-research.com)
the receiver operating characteristic (ROC) curve was used to evaluate the diagnostic power of the nomogram model for screening hypertension risk. (frontiersin.org)
Hypertension is a very common clinical syndrome characterized by elevated arterial blood pressure ( 1 ). (frontiersin.org)
Investigators also found that inhibition of inflammation can alleviate hypertension in animal models ( 5 , 6 ). (frontiersin.org)
Aims: Estimation of prognosis in pulmonary arterial hypertension (PAH) has been influenced by that various risk stratification models use different numbers of prognostic parameters, as well as the lack of a comprehensive and time-saving risk assessment calculator. (lu.se)
Risk scores were calculated using the original Swedish Pulmonary Arterial Hypertension Registry (SPAHR)/Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA) three-strata model, the updated SPAHR three-strata model with divided intermediate risk, and the simplified three-parameter COMPERA 2.0 four-strata model. (lu.se)
Our findings support the 2022 ESC/ERS pulmonary hypertension guidelines' strategy for risk stratification suggesting the utilization of a three-strata model at baseline and a simplified four-strata model at follow-ups. (lu.se)
Our results support the 2022 ESC/ERS pulmonary hypertension guidelines' risk stratification strategy, additionally suggesting the updated SPAHR three-strata model with divided intermediate risk, as a promising complement to the new simplified three-parameter COMPERA 2.0 four-strata strategy, when a more comprehensive overview is needed. (lu.se)
Pulmonary arterial hypertension (PAH) is a lethal disease [1]. (keio.ac.jp)
The prevalence of hypertension was esti- mated among study participants, and socio-demographic, lifestyle, anthropometric, metabolic and HIV/ART-related factors associated with hypertension were determined by logistic regression modelling. (bvsalud.org)

Hispanics/Latinos are at increased risk for cardiovascular disease and cognitive decline and dementias. (nih.gov)
Cardiovascular impairment contributes to increased mortality in preterm infants with chronic lung disease. (biomedcentral.com)
The endothelin-1 receptor antagonist macitentan attenuated cardiovascular remodelling in an infant rat model for preterm chronic lung disease. (biomedcentral.com)
This study underscores the potential of macitentan to reduce cardiovascular morbidity in preterm infants with chronic lung disease. (biomedcentral.com)
Previously published cohort studies in clinical populations have suggested that obstructive sleep apnea (OSA) is a risk factor for mortality associated with cardiovascular disease. (nih.gov)
Despite the small number of patients in this study, this association was also confirmed in a multivariate logistic regression model adjusted for sex and previous cardiovascular disease (odds ratio 0.035, 95% confidence interval 0.001-0.94). (cdc.gov)
Cardiovascular disease is the leading cause of death worldwide, with an especially devastating impact in low-to-medium income countries. (revespcardiol.org)
Cardiovascular disease has been elevated to this position by a combination of factors that include urbanization and its attendant effects, such as obesity, a sedentary lifestyle, changes in dietary habits, and smoking. (revespcardiol.org)
Given the enormous extent of the problem and the complexity of its causes, which include cultural, social, political, and health care factors, an equally sophisticated and comprehensive strategy is required to combat cardiovascular disease on a global scale. (revespcardiol.org)
Thus, our efforts should be concentrated not only on cardiovascular disease treatment and prevention, but also on health promotion and primordial prevention. (revespcardiol.org)
The effect of high levels of physical activity and relationship between daily total physical activity and the risk of cardiovascular disease (CVD) among hypertensive people were not clear. (biomedcentral.com)
PA can provide a wide range of favorable response in cardiovascular system such as improving the dynamics of cardiovascular system and reducing the prevalence of coronary heart disease and cardiomyopathy [ 7 ]. (biomedcentral.com)
In a pathological context, detailed assessment of coronary responses to infused vasodilators may give valuable complementary information on microvascular functional defects in disease models. (biomedcentral.com)
Low-density lipoprotein (LDL) particles cause atherosclerotic cardiovascular disease (ASCVD) through their retention, modification, and accumulation within the arterial intima. (oulu.fi)
We aimed to assess the prevalence of CVD and cardiovascular risk profile in inflammatory bowel disease (IBD), psoriasis (PSO) and spondylarthropathies (SpA). (ecco-ibd.eu)
The distributed parameter model can also be used for absolute quantification but has not been applied in patients with coronary artery disease. (essex.ac.uk)
We also performed analysis using both models of single bolus data obtained from five patients with coronary artery disease and findings were compared against independent invasive coronary angiography and fractional flow reserve. (essex.ac.uk)
The Framingham risk score is a robust algorithm to predict cardiovascular disease (CVD) risk based on demographic and clinical factors among European Americans. (cdc.gov)
Although a recent joint society scientific statement (the American Association of Cardiovascular Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology) suggests home-based cardiac rehab (CR) is appropriate for low- and moderate-risk patients, there are no paradigms to define such individuals with coronary heart disease. (journaltocs.ac.uk)
We reviewed a decade of data from all patients with coronary heart disease enrolled in a single CR center (University of Michigan) to identify the prevalence of low-risk factors, which may inform on consideration for participation in alternative models of CR. (journaltocs.ac.uk)
In this observational study, we provide a first paradigm of identifying factors among coronary heart disease patients that may be considered low-risk and likely high-gain for participation in alternative models of CR. (journaltocs.ac.uk)
PAD ASCVD events, in particular lower limb artery disease, was predominant and requires active diagnosis and intensive management, while controlling modifiable traditional cardiovascular risk factors. (natap.org)
An increased risk of cardiovascular disease (CVD) was reported in patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV), without identifying factors associated with atherosclerotic CVD (ASCVD) events. (natap.org)
Patients with chronic coronary artery disease (CAD) and/or peripheral artery disease (PAD) have increased risks for cardiovascular (CV)-related morbidity and mortality. (ahdbonline.com)
1,2 CAD is the most common form of cardiovascular (CV) disease and is a leading cause of death in the United States. (ahdbonline.com)
Assessment of left ventricular diastolic function is useful in risk stratification for patients with cardiovascular disease and can provide a diagnostic clue for heart failure with preserved ejection fraction. (medsci.org)
And it can play a role in cardiovascular disease research. (immune-system-research.com)
Nowhere are the "blessings of the grape" so evident as in prevention of cardiovascular disease. (lifeextension.com)
Cardiovascular disease involves a cascade of aberrant biological processes, but one area of interest even amongst the medical establishment is LDL oxidation. (lifeextension.com)
Model-based computer-aided method for diagnosis of cardiovascular disease using IR thermogram. (biomedres.info)
Thus the aim of this work was to bring out the potential of thermal imaging in diagnosing the cardiovascular disease in comparison with the standard techniques. (biomedres.info)
Thus the inclusion of IR thermogram in the CAD model along with standard variables improves the accuracy of cardiovascular disease evaluation. (biomedres.info)
In patients with inflammatory bowel disease (IBD) the cardiovascular risk is increased despite the low prevalence of traditional cardiovascular risk factors. (lww.com)
Atherosclerotic cardiovascular disease is the leading cause of death in the Western world. (biomedcentral.com)
Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have increased cardiovascular disease (CVD) risk compared with the general population. (bmj.com)
Obstructive sleep apnea (OSA) has become an important risk factor for cardiovascular disease (CVD). (acc.org)
In view of To adjust the rates, we used the direct become the most important health this, and reports of the varying distri- standardization method and the WHO problem and cause of mortality in bution of cardiovascular disease risk standard population ( 18 ). (who.int)
The worldwide incidence of type 2 diabetes (T2D) in children and for cardiovascular disease in adults. (who.int)
12] Screening should commence at 2 years trial, small very low-density lipoprotein (VLDL), small high- of age if there is a family history of hypercholesterolaemia, early density lipoprotein (HDL), medium low-density lipoprotein (LDL) cardiovascular disease or if the family history is unknown. (who.int)
2005-2018 National Health and Nutrition Examination Survey for Cardiovascular Disease Risk Among US Adults, National Health adults aged 20 to 39 years (n = 10,588) and adults aged 40 to 79 and Nutrition Examination Survey, 2005-2018. (cdc.gov)
Depression is also people aged 40 to 79 years and 2) high lifetime CVD risk preval- an established marker of incident cardiovascular disease (CVD) ence for people aged 20 to 39 years. (cdc.gov)

Up to 40% of the US population will develop type 2 diabetes during their lifetime, and type 2 diabetes is an important contributor to major adverse cardiovascular events (MACE) such as myocardial infarction and stroke-the leading causes of morbidity and mortality in Western countries [ 2 ]. (springer.com)
Polyvascular atherosclerosis (PVA) coexisting in several territories has an adverse effect on cardiovascular morbidity and mortality. (who.int)
Ambient air pollution is associated with increased cardiovascular morbidity and mortality. (biomedcentral.com)

Journal of Cardiovascular Magnetic Resonance, 17 (1). (essex.ac.uk)

The Cox proportional hazard models were introduced to investigate the association between total physical activity and CVDs, reporting as hazard ratios (HR) and 95% confidence intervals (CIs). (biomedcentral.com)

These findings suggest that in overweight patients cardiovascular and renal values depend chiefly on body weight and insulin, but that in normal weight hypertensives the renin-angiotensin system may play the major role. (scienceopen.com)
Diabetes is serious due to its complications, namely: cardiovascular ailments, cerebral vascular accidents, renal insufficiency, blindness, sexual impotence and gangrene of the feet leading to amputation. (who.int)
These specific conditions in the oral cavity may create foci of infection that can affect many other vital systems, such as the cardiovascular and renal systems. (medscape.com)

Additionally, cardiovascular remodelling with decreased pulmonary capillary density and increased arterial wall thickness contributes to poor outcomes [ 10 ]. (biomedcentral.com)
Clinical decision-making based on overall cardiovascular risk in addition to individual risk factors can improve outcomes, as demonstrated for antihypertensive treatment [ 12 ]. (springer.com)
BACKGROUND: Although welding fume exposure is associated with adverse cardiovascular outcomes, the mechanisms remain unclear. (cdc.gov)
In the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) clinical trial of such patients, rivaroxaban plus aspirin demonstrated a significant reduction in major adverse CV events (MACE), a composite of stroke, myocardial infarction, and CV death, and major adverse limb events (MALE), a composite of chronic and acute limb ischemia, and major amputation resulting from vascular events, versus aspirin alone. (ahdbonline.com)
Sensitivity analyses under recessive and additive models for the two outcomes with adequate data (major adverse cardiovascular events and stent thrombosis) produced results in the same direction but with larger effect sizes than the dominant model. (ahrq.gov)

Univariate analyses and multivariate Cox proportional hazards modelling were used to ascertain the association between sleep apnea and mortality after adjustment for age, gender, body mass index, mean arterial pressure, total cholesterol, high-density lipoprotein cholesterol, diabetes, and medically diagnosed angina in those free from heart attack or stroke at baseline (n = 380). (nih.gov)
The purpose of this study was to compare the effects of aerobic, resistance, or combined exercise training on cardiovascular autonomic control and mortality in diabetic ovariectomized rats. (fapesp.br)
In conclusion, all training protocols led to reduced mortality, which may be due to an increase in physical capacity and to cardiovascular and autonomic benefits following training, regardless of any improvement in glycemic control. (fapesp.br)
CONCLUSIONS: In this study of 16 cohorts, there was no association between air pollution exposure and nonmalignant respiratory mortality. (surrey.ac.uk)
At baseline, both the original SPAHR/COMPERA and the updated SPAHR models, using up to six parameters, provided the highest accuracy (uAUC = 0.73 for both models) in predicting 1-, 3-, and 5-year mortality. (lu.se)
At follow-ups, the updated SPAHR model with divided intermediate risk (7-11 parameters) provided the highest accuracy for 1-, 3-, and 5-year mortality (uAUC = 0.90), followed by the original SPAHR/COMPERA model (7-11 parameters) (uAUC = 0.88) and the COMPERA 2.0 model (uAUC = 0.85). (lu.se)

To determine whether a dose-response relationship exists between short-term oral prednisone administration and common clinicopathologic variables, cardiovascular biomarkers, and systolic arterial blood pressure (SAP) in healthy dogs. (avma.org)
We identified eight protein biomarkers, four of which are novel, for risk of MACE in community residents with type 2 diabetes, and found improved risk prediction by combining multiplex proteomics with an established risk model. (springer.com)

Multivariate linear and logistic regression models corrected for age and sex were applied to identify differences between groups. (ecco-ibd.eu)

Although these interactions remain to be further examined in humans, the physiological functions of taurine appear to be inconsistent with the adverse cardiovascular symptoms associated with excessive consumption of caffeine-taurine containing beverages. (researchgate.net)
Multiplex proteomics could improve understanding and risk prediction of major adverse cardiovascular events (MACE) in type 2 diabetes. (springer.com)
Cardiovascular prevention is further complicated by increased rates of drug side effects in people with diabetes, including potential adverse glycaemic effects of lipid-modifying agents [ 6 , 7 ]. (springer.com)

The cardiovascular AF in MSA is thought to be mainly due to a progressive neurodegeneration of several areas involved in autonomic control of the cardiovascular system such as inter alia , cholinergic neurons in the ventrolateral ambiguous nucleus and dorsal motor nucleus of the vagus nerve ( 5 ). (frontiersin.org)

PON2 may be a potential therapeutic target to reduce arterial remodeling after angioplasty in hypertensive patients. (hindawi.com)

In conclusion, this thesis presents experimental and clinical knowledge to better understand aspects of existent antiplatelet treatments and the studies also provide inputs to the development of future treatment modalities. (avhandlingar.se)
Conclusions- This study identified a small and transient decline in concordance between ICD-CM codes and stroke clinical diagnoses during the coding transition, indicating no substantial impact on the overall identification of stroke patients. (cdc.gov)
The addition of baPWV and PWDC to a clinical model improved the prediction of high E/Ea and LVDD. (medsci.org)
These phenotypes provided independent capacity of prediction of T2DM incidence after adjustment for age, sex, tobacco and alcohol consumption, obesity and number of SMet features with a c-Harrell=0.84.Conclusions: MAFLD interplay with MetS and PreDM might help to discriminate patient risk of T2DM in the clinical setting through metabolic remodelling-based phenotypes. (unav.edu)

The rat thoracic aortic smooth muscle cells (A10 cells) stimulated by AngII were used as the in vitro neointimal hyperplasia model, where AngII significantly induced the proliferation and migration in A10 cells. (hindawi.com)
AF097191) has been amplified from 5 different arterial samples, including 1 aortic aneurysm ( 7 ), and a relationship (p = 0.009) between cerebral hemorrhage and serologic evidence of Parachlamydia infection has been reported ( 8 ). (cdc.gov)
In conclusion, patients with recessive FBLN4 mutations are predominantly characterized by aortic aneurysms, arterial tortuosity and stenosis. (uzh.ch)
Here, we aimed to test the hypothesis that aortic stiffening is more easily reverted by long-term anti-TNF therapy within few years from the diagnosis of IBD, when structural alterations of the arterial wall could be not yet fully established. (lww.com)

Background Mathematical modeling of cardiovascular magnetic resonance perfusion data allows absolute quantification of myocardial blood flow. (essex.ac.uk)
We validated the accuracy of each model in detecting reduced myocardial blood flow in stenotic vessels versus gold-standard invasive methods. (essex.ac.uk)
Distributed parameter modeling showed excellent accuracy in detecting reduced myocardial blood flow in all stenotic vessels. (essex.ac.uk)

To assess this flow diverting strategy for popliteal aneurysms, flow profiles and thrombus formation likelihood were investigated in popliteal aneurysm models. (springer.com)
In a second group of 22 patients presenting with arterial tortuosity, stenosis and aneurysms, FBLN4 mutations were identified in three patients, two homozygous missense mutations (p.Glu126Lys and p.Ala397Thr) and compound heterozygosity for missense mutation p.Glu126Val and frameshift mutation c.577delC. (uzh.ch)

As an original technique, a cine arterial spin labeling (ASL) cardiovascular magnetic resonance approach is demonstrated to be able to produce dynamic MBF maps across the cardiac cycle in rats. (biomedcentral.com)
Cyclic change of regional MBV in the mouse heart has already been reported using cardiovascular magnetic resonance (CMR) based on the correlation with cyclic variation in the steady-state T 2 * shortening effect of an ultrasmall iron oxide nanoparticle intravascular contrast agent [ 9 ]. (biomedcentral.com)

Newer glucose-lowering drugs such as sodium-glucose co-transporter 2 inhibitors, and cholesterol-modifying agents such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, in addition to standard treatment reduce cardiovascular risk in high-risk individuals [ 8 , 9 ]. (springer.com)

Macitentan, an endothelin-1 receptor antagonist, has the potential to attenuate pulmonary and cardiovascular remodelling. (biomedcentral.com)

IBD patients have a more favorable cardiovascular risk profile, as compared to PSO and SpA. (ecco-ibd.eu)

as elsewhere in the arterial circulation, it is the pressure difference between the aorta and the peripheral capillaries that provides the driving force for coronary circulation. (biomedcentral.com)

In Phase I (calibration phase), arterial and jugular bulb venous blood were obtained for co-oximetry simultaneously with NIRS signals to calibrate an algorithm for NIRS regional cerebral saturtion (rScO 2 ) to a weighted average cerebral saturation (SavO 2 = 0.7 SjO2 + 0.3 SaO 2 ). (nonin.com)
In Phase II, (validation phase), arterial and jugular bulb venous samples to calculate SavO 2 were compared with NIRS rScO 2 from the device algorithm. (nonin.com)

Results Estimated by Cox proportional hazard models, the HRs of the composite CVD end point for patients with colectomy compared with the control patients were not significantly reduced (HR=0.94, 95% confidence limits 0.85 to 1.04). (bmj.com)
Cohort-specific hazard ratios obtained by Cox proportional hazard models from standardized individual cohort analyses were combined using metaanalyses. (surrey.ac.uk)

This study assessed 80 cardiovascular and inflammatory proteins for biomarker discovery and prediction of MACE in type 2 diabetes. (springer.com)
We used gradient-boosted machine learning and lasso regularised Cox regression in a random 75% training subsample to assess whether adding proteins to risk factors included in the Swedish National Diabetes Register risk model would improve the prediction of MACE in the separate 25% test subsample. (springer.com)
Multiprotein arrays could be useful in identifying individuals with type 2 diabetes who are at highest risk of a cardiovascular event. (springer.com)

We therefore evaluated the various European Society of Cardiology (ESC)-/European Respiratory Society (ERS)-based three-and four-strata risk stratification models and established a comprehensive internet-based calculator to facilitate risk assessment. (lu.se)
Conclusions: The present study facilitates risk assessment in PAH by introducing a comprehensive internet-based risk score calculator (https://www.svefph.se/risk-stratification). (lu.se)
Our findings furthermore support the utility of the updated SPAHR model with divided intermediate risk, when a more comprehensive assessment is needed at follow-ups, complementing the three-parameter COMPERA 2.0 model. (lu.se)
To carry out these legislative mandates, ATSDR's Division of Toxicology (DT) has developed and coordinated a mixtures program that includes trend analysis to identify the mixtures most often found in environmental media, in vivo and in vitro toxicological testing of mixtures, quantitative modeling of joint action, and methodological development for assessment of joint toxicity. (cdc.gov)

Preeclampsia is followed by the delay in sympathetic nervous system development in the offspring, which is accompanied by structural and functional alterations in the cardiovascular system. (atlantis-press.com)

Because exposure to cardiovascular risk factors occurs from early ages, this strategy must be expanded and adjusted throughout the life of an individual. (revespcardiol.org)
CONCLUSIONS: Subsequent to welding fume exposure, there is an increase in afternoon augmentation index and a decrease in next-morning augmentation index, with greater changes after consecutive days of exposure. (cdc.gov)
MEASUREMENTS AND MAIN RESULTS: Air pollution exposure was estimated by land use regression models at the baseline residential addresses of study participants and traffic-proximity variables were derived from geographical databases following a standardized procedure within the ESCAPE study. (surrey.ac.uk)
Received May 14, 1997 variability and to use this measure of variability to Using the Monte Carlo method and physiologically derive a safe exposure limit or guidance value for inha- based pharmacokinetic modeling, an occupational in- lation of trichloroethylene (TRI) in an occupational set- halation exposure to trichloroethylene consisting of ting. (cdc.gov)

In the last paper we investigate the mechanisms behind platelet-endothelial cell interactions in a mouse model of arterial inflammation. (avhandlingar.se)
Furthermore, in a moue model of arterial inflammation we found that P-selectin is responsible for a significant part of the platelet-leukocyte interactions. (avhandlingar.se)
3 While many factors-ranging from vitamin K deficiency to elevated glucose levels-contribute to cardiovascular risk, perhaps one of the most insidious triggers is inflammation. (lifeextension.com)

Three interventions in animal models to rationally alter LDL composition lowered its susceptibility to aggregate and slowed atherosclerosis. (oulu.fi)
In contrast, brachial-ankle pulse wave velocity (baPWV) reflected a composite of several arterial segments, some of which were prone to arteriosclerosis alone (brachial and distal arteries) and some to both atherosclerosis and arteriosclerosis (aorta and femoral arteries). (medsci.org)

Linear mixed-effects modeling was used to compare changes in variables from baseline (day 1 for the same experiment) among treatment conditions. (avma.org)
We used linear mixed models adjusting for baseline augmentation index, smoking, age, and time to evaluate the effects of welding (binary) and PM2.5 (continuous) on augmentation index levels. (cdc.gov)
At baseline, utilizing the original or the updated SPAHR models using up to six parameters was favourable, the latter model additionally offering sub-characterization of the intermediate risk group. (lu.se)

However, the influence of pharmacological ET-1 receptor blockade on cardiovascular remodelling in the context of BPD has neither been examined in human patients nor in animal models. (biomedcentral.com)
In conclusion, BMS 182874 is an orally effective and highly selective endothelin receptor ET A antagonist. (immune-system-research.com)

Factors associated with ASCVD were identified using cause-specific Cox proportional hazards models. (natap.org)

Angiotensin II (AngII), as the major effector of the renin-angiotensin-aldosterone system (RAAS), plays an important role in regulating blood pressure and arterial remodeling [ 5 ]. (hindawi.com)
Patients ≥18 years underwent body measurements (blood pressure (BP), BMI, waist and hip circumference), laboratory analysis (plasma glucose, lipid spectrum) and completed a cardiovascular questionnaire (e.g. history of CVD, medication use). (ecco-ibd.eu)
The model was verified by the dam's blood pressure (BP) elevation (tail-cuff) and creatinine clearance reduction (metabolic cages) compared to control dams. (atlantis-press.com)
Nonetheless, it will be shown that the hemodynamic equations developed by Euler about 275 years ago, still undergird the most advanced numerical methods in use today for blood flow analysis in arterial networks. (scirp.org)
In fact, although in the introduction to the problem (paragraphs 1-8), Euler focuses on the discussion on blood flow through arteries, to such a degree to even proposing adhoc models for the behavior of their elastic cross-sections, surprisingly, and also somehow disappointing, is that the main body of the manuscript (paragraphs 9-34) is devoted to the modeling of flows through rigid tubes, driven by a piston pump. (scirp.org)
It is well known that the modern understanding of the cardiovascular system undoubtedly starts with the work of William Harvey (1578-1657) who published his discovery of the circulation of blood in 1628. (scirp.org)
This would avoid unprecedented iatrogenic loss of part or entire distal part of the upper limb due to loss of arterial blood supply. (bvsalud.org)
They were screened for high blood pressure and associated cardiovascular risk factors by an interview questionnaire. (who.int)

Measuring circulating proteins with presumed roles in cardiovascular pathology by targeted proteomics is a promising approach for biomarker discovery [ 15 ]. (springer.com)
Involvement of the FBLN4 gene in cardiovascular pathology was shown in a murine model and in three patients affected with cutis laxa in association with systemic involvement. (uzh.ch)
Methods Circulating (n = 179) and hepatic expression (n = 95) of ghrelin and LEAP-2 were measured in patients with severe obesity and available liver pathology analysis undergoing Roux-en-Y gastric bypass (RYGB). (unav.edu)

Many studies in MSA patients have already depicted cardiovascular autonomic impairments with a reduction in sympathetic and parasympathetic activities ( 6 - 9 ). (frontiersin.org)

The model inputs were taken from the COMPASS study (ie, the efficacy and safety of rivaroxaban plus aspirin vs aspirin), Optum Integrated Database (ie, the prevalence of chronic CAD and/or PAD, incidence rates, and healthcare costs of MACE, MALE, and major bleeding), and the RED BOOK (ie, wholesale drug acquisition costs). (ahdbonline.com)

Hospital - at risk of cardiovascular complications? (who.int)
Poor glycaemic control, dyslipidaemia and HT are common in diabetic children, putting them at risk of cardiovascular complications in adulthood. (who.int)

The in vivo neointimal hyperplasia model was established 2 weeks after the carotid artery balloon injury in SHR rats. (hindawi.com)

We have used human microvascular endothelial cells (HMEC) to study the combined effects of a model air pollutant, diesel exhaust particles (DEP), and oxidized 1-palmitoyl-2-arachidonyl- sn -glycero-3-phosphorylcholine (ox-PAPC) on genome-wide gene expression. (biomedcentral.com)
Although the mechanism of cardiovascular injury by PM is poorly understood, it has been shown that the particles are coated by a number of chemical compounds, including organic hydrocarbons (for example, polycyclic aromatic hydrocarbons and quinones), transition metals, sulfates and nitrates. (biomedcentral.com)

Peripheral arteria3

Diseases17

Increased arterial stiffness3

Stiffness15

Combating cardiovascular disease1

Hypertension14

Disease41

Morbidity3

Journal of Cardiovascular Magnetic1

CVDs1

Renal3

Outcomes5

Mortality6

Biomarkers2

Logistic regression1

Adverse3

Autonomic control1

Hypertensive patients1

Clinical4

Aortic4

Myocardial3

Aneurysms2

Magnetic resonance2

Reduce cardiovascular1

Pulmonary1

Favorable1

Coronary1

Venous2

Proportional hazard models2

Diabetes3

Assessment4

Alterations1

Exposure4

Inflammation3

Atherosclerosis2

Baseline3

Receptor2

ASCVD1

Blood8

Pathology3

Reduction1

Chronic1

Complications2

Rats1

Particles2