• For poultry and swine, arsanilic acid was among four arsenical veterinary drugs, along with carbarsone, nitarsone, roxarsone, approved by the U.S. Food and Drug Administration (FDA). (wikipedia.org)
  • Arsanilic acid, carbarsone, nitarsone, and roxarsone were formerly used in poultry feed in order to promote growth and increase feed conversion. (wikipedia.org)
  • On September of that year, Zoetis and Fleming Laboratories, the drugs' sponsors, voluntarily withdrew the FDA approvals for arsanilic acid, carbarsone, and roxarsone, leaving only nitarsone approved until its approval for use in animal feed was withdrawn by the FDA in 2015. (wikipedia.org)
  • A total of 552 Campylobacter isolates (281 Campylobacter jejuni and 271 Campylobacter coli ) isolated from retail meat samples were subjected to arsenic resistance profiling using the following arsenic compounds: arsanilic acid (4-2,048 μg/mL), roxarsone (4-2048 μg/mL), arsenate (16-8,192 μg/mL) and arsenite (4-2,048 μg/mL). (mdpi.com)
  • Most of the 552 Campylobacter isolates were able to survive at higher concentrations of arsanilic acid (512-2,048 μg/mL), roxarsone (512-2,048 μg/mL), and arsenate (128-1,024 μg/mL), but at lower concentrations for arsenite (4-16 μg/mL). (mdpi.com)
  • Carbarsone is one of four arsenical animal drugs approved by the U.S. Food and Drug Administration for use in poultry and/or swine, along with nitarsone, arsanilic acid, and roxarsone. (wikipedia.org)
  • In September 2013, the FDA announced that Zoetis and Fleming Laboratories would voluntarily withdraw current roxarsone, arsanilic acid, and carbarsone approvals, leaving only nitarsone approvals in place. (wikipedia.org)
  • The drugs -- roxarsone, carbarsone and arsanilic acid -- were added to feed for chicken, turkeys and pigs to prevent disease and promote growth. (healthmonitor.com)
  • A novel method has been developed to detect two organic arsenic animal feed additives including roxarsone and p-arsanilic acid, as well as other arsenic species, by using high-performance liquid chromatography coupled to an inductively coupled plasma mass spectrometer (HPLC-ICP-MS). (allaboutfeed.net)
  • Roxarsone was banned alongside carbarsone and arsanilic acid. (kindness2.com)
  • In 2013, the FDA denied petitions by the Center for Food Safety and by the Institute for Agriculture and Trade Policy seeking revocation of approvals of the arsenical animal drugs, but the drugs' sponsors voluntarily requested the FDA to withdraw approvals of three, including arsanilic acid, leaving only nitarsone approved. (wikipedia.org)
  • These include Pfizer's own feed additives containing nitarsone, another arsenic compound as well as those containing arsanilic acid and carbarsone. (commondreams.org)
  • The CFS and IATP petition calls for a more comprehensive ban, one that would include Arsanilic acid, Nitarsone, and Carbarsone, all commonly used compounds that contain arsenicals. (foodsafetynews.com)
  • Arsanilic acid, also known as aminophenyl arsenic acid or aminophenyl arsonic acid, is an organoarsenic compound, an amino derivative of phenylarsonic acid whose amine group is in the 4-position. (wikipedia.org)
  • In Germany, Paul Ehrlich inferred Béchamp's report of Atoxyl's structure incorrect, and Ehrlich with his chief organic chemist Alfred Bertheim found its correct structure-aminophenyl arsenic acid or aminophenyl arsonic acid-which suggested possible derivatives. (wikipedia.org)
  • Arsonic acids are a subset of organoarsenic compounds defined as oxyacids where a pentavalent arsenic atom is bonded to two hydroxyl groups, a third oxygen atom (this one with a double bond), and an organic substituent. (wikipedia.org)
  • The salts/conjugate bases of arsonic acids are called arsonates. (wikipedia.org)
  • Like all arsenic-containing compounds, arsonic acids are toxic and carcinogenic to humans. (wikipedia.org)
  • Arsonic acid refers to H3AsO3, the case where the substituent is a single hydrogen atom. (wikipedia.org)
  • The other arsonic acids can simply be viewed as hydrocarbyl derivatives of this base case. (wikipedia.org)
  • Arsenic acid is technically not an arsonic acid because the substituent is a hydroxyl group, not a hydrocarbyl group, so arsenic acid has three hydroxyl groups bound to the arsenic atom, while arsonic acids only have two. (wikipedia.org)
  • Polyelectrolytes with arsonic acid groups were synthetized by chemical modification of poly( p -acryloyloxibenzaldehyde) using ortho- and para- aminophenylarsonic acids (PE-1 and PE-2). (springer.com)
  • Meanwhile, macroelectrolytes with arsonic acid groups were synthesized from hexachlorocyclotriphosphazene using arsanilic acids in ortho- and para- position (ME-1 and ME-2). (springer.com)
  • Because of the position of arsonic acid groups, the degree of substitution of polyelectrolytes and macroelectrolytes, and the dissociation in liquid media, different nanostructures were obtained with them using the colloidal method. (springer.com)
  • 5,6 Proanthocyanidins and other compounds such as phenolics, organic acids and sugars contribute to supporting a healthy urinary tract. (azoprofessional.com)
  • Prostaglandins are polyunsaturated fatty acid compounds that are part of the eicosanoid group of fatty acids, which regulate cellular functioning in response to injury. (youmemindbody.com)
  • C6H5NH2 + H3AsO4 → H2O3AsC6H4NH2 + H2O Arsanilic acid occurs as a zwitterion, H3N+C6H4AsO3H−, yet is typically represented with the non-zwitterionic formula H2NC6H4AsO3H2. (wikipedia.org)
  • The process involves the reaction of aniline and arsenic acid via an electrophilic aromatic substitution reaction. (wikipedia.org)
  • In 1859, in France, while developing aniline dyes, Antoine Béchamp synthesized a chemical that he identified, if incorrectly, as arsenic acid anilide. (wikipedia.org)
  • Also biologist, physician, and pharmacist, Béchamp reported it 40 to 50 times less toxic as a drug than arsenic acid, and named it Atoxyl, the first organic arsenical drug. (wikipedia.org)
  • Arsenic acid results when the substituent is a hydroxyl group. (wikipedia.org)
  • Acid CAS 96-97-9 Light Yellow Crystalline Powder Quick detail Product Name: 5-Nitrosalicylic acid Synonyms: 2-hydroxy-5-nitro-benzoicaci;AURORA KA-2534;ANILOTIC ACID ;2-HYDROXY-5-NITROBENZOIC ACID ;5-NITROSALICYLIC ACID ;5-NITRO-2-HYDROXY-BENZOIC ACID . (chinacomputerparts.com)
  • Esterases in granulocytic leukocytes catalyze the hydrolysis of the derivatized pyrrole amino acid ester to liberate 3-hydroxy-5-phenyl pyrrole. (drugstorepdfsearch.com)
  • At the acid pH of the reagent area, nitrite in the urine reacts with p-arsanilic acid to form a diazonium compound. (drugstorepdfsearch.com)
  • Arsanilic acid saw long use as a veterinary feed additive promoting growth and to prevent or treat dysentery in poultry and swine. (wikipedia.org)
  • A61K47/642 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. (google.com)
  • Considering p -arsanilic acid ( p -ASA) as an organoarsenic pollutant, monitoring concentration of p -ASA is significant to maintain environmental security. (rsc.org)
  • p -Arsanilic acid ( p -ASA), an emerging organoarsenic pollutant, can be converted into highly poisonous inorganic arsenic species (such as arsenate and arsenite) by biological or chemical reactions, causing serious arsenic pollution in groundwater and surface water. (rsc.org)
  • Boutwell RK (1963) A carcinogenicity evaluation of potassium arsenite and arsanilic acid. (springer.com)
  • This study was performed to assess the neurotoxic effects of methylmercury, arsanilic acid and danofloxacin by quantification of neural-specific proteins in vitro. (bvsalud.org)
  • The N-acetylation of arsanilic acid In vitro by mammalian enzymes. (statescale.cf)
  • Hepatic differentiation of human adipose tissue-derived mesenchymal stem cells and adverse effects of arsanilic acid and acetaminophen during in vitro hepatic developmental stage. (geneticsmr.com)
  • Acetylcholinesterase activity was inhibited by relatively low concentrations of methylmercury and arsanilic acid during the differentiating stage while this activity was inhibited only by more than 40 microM of danofloxacin in the differentiated stage. (bvsalud.org)
  • Modulation of antibody affinity by an engineered amino acid substitution. (harvard.edu)
  • The antibody-arsanilic acid solution is then dialyzed against saline to get rid of the arsanilic acid. (nih.gov)
  • The monoclonal anti-NAGA Id antibody, termed CId-1, reacted with affinity purified antibodies to NAGA, but not with antibodies specific for PABA, arsanilic acid (Ars), phosphorylcholine (PC), or with normal chicken IgG and IgM. (gallusimmunotech.com)
  • Abstract Poly(L-lactic acid) (PLLA) of high molecular weight was prepared by chain extending reaction in a micro-compounder. (chemistrymag.org)
  • Phosphites were used as chain extenders to increase the molecular weight of the PLLA prepolymer that was prepared by bulk polycondensation of L-lactic acid. (chemistrymag.org)
  • Still sometimes used in laboratories, arsanilic acid's legacy is principally through its influence on Paul Ehrlich in launching the chemotherapeutic approach to treating infectious diseases of humans. (wikipedia.org)
  • We are now beginning to get good x-ray photographs of large polypeptides, with fifty or one hundred amino acid residues per molecule, and I think that we shall succeed in making complete structure determinations of these. (oregonstate.edu)
  • I am confident that this method of attack, using synthetic polypeptides of known amino acid composition, which might be called artificial proteins, will lead ultimately to the solution of the protein problem. (oregonstate.edu)
  • 3. The method of claim 1 , wherein the polishing additive is selected from the group consisting of aniline, anthranilic acid, orthanilic acid, salts thereof, and combinations thereof. (google.com.au)
  • Inorganic salts or organic esters of arsenious acid. (harvard.edu)
  • In a modified Ehrlich reaction, p-diethylaminobenzaldehyde in conjunction with a color enhancer reacts with urobilinogen in a strongly acid medium to produce a pink-red color. (drugstorepdfsearch.com)
  • Detection of p -arsanilic acid ( p -ASA) is significant for environmental risk assessment as it can be converted into highly toxic inorganic arsenic species. (rsc.org)
  • Composition of Dinitrosalicylic acid (DNSA) reagent NaOH - 10.0 g Phenol - 2.0 g DNSA - 2.0 g Distilled Water - 1000 mL DNSA reagent was stored in an amber bottle at 4 °C till further use. (hypothes.is)
  • Density Functional Theory Calculations on the Complexation of p-Arsanilic Acid with Hydrated Iron Oxide Clusters: Structures, Reaction Energies and Transition States. (wlu.ca)
  • Glucose oxidase catalyzes the formation of gluconic acid and hydrogen peroxide from the oxidation of glucose. (drugstorepdfsearch.com)
  • Description: Orotic acid (OA) is an intermediate in pyrimidine metabolism. (gemini-genomics.com)