• Vasoocclusion also is in part due to the interaction between sickled cells and the vascular endothelium. (medscape.com)
  • A malfunction of the vascular endothelium arises at an early stage in the development of pulmonary arterial hypertension. (medicalnewstoday.com)
  • The vascular endothelium, the innermost layer of blood vessels, provides a dynamic interface between the circulating blood and various tissues/organs and thereby maintaining tissue homeostasis. (nature.com)
  • Taken together, the concerted actions of above factors lead to dysfunctional status of the vascular endothelium (endothelial dysfunction) (Fig. 1 ) [ 14 ]. (nature.com)
  • Normally, the endothelium forms an integral cellular barrier to regulate vascular homeostasis. (surrey.ac.uk)
  • MR imaging is frequently performed with MRA to distinguish between vascular malformations, vascular tumours, and perivascular tumours. (springer.com)
  • all other abnormalities are malformations resulting from anomalous development of vascular plexuses. (medscape.com)
  • Hemangiomas exhibit both a proliferating phase and an involuting phase, whereas vascular malformations are more stable and fail to regress. (medscape.com)
  • This scheme is straightforward and essentially divides the vasoformative tumors into 2 broad groups: hemangiomas and vascular malformations (see Table 1 below). (medscape.com)
  • The vascular malformations can be further subdivided into arterial, venous, capillary, and lymphatic malformations. (medscape.com)
  • On examination of the oral cavity, the vascular malformations of the mucosa and the adjacent soft tissues are usually readily apparent. (medscape.com)
  • These abnormalities can arise from traumatic brain injuries, strokes and other vascular problems, infections of the nervous system (meningitis or encephalitis), congenital malformations, brain tumors or metabolic abnormalities. (hopkinsmedicine.org)
  • Port-wine stains are capillary vascular malformations that are present at birth and that manifest. (msdmanuals.com)
  • Lymphatic Malformations Lymphatic vascular malformations are elevated lesions composed of dilated lymphatic vessels. (msdmanuals.com)
  • Vascular endothelial cells form the interface between recipient tissues and circulating alloreactive donor T cells after allogeneic stem cell transplantation. (nih.gov)
  • Inflammation and endothelial injury were assessed in selected samples by immunostaining for CD8 T cells, activated cytotoxic T lymphocytes, and vascular endothelial cells. (nih.gov)
  • Endothelial cells are sentinels lining the innermost layer of blood vessel that gatekeep micro- and macro-vascular health by sensing pathogen/danger signals and secreting vasoactive molecules. (nature.com)
  • In general, someone's own vein (autograft) is the preferred graft material (or conduit) for a vascular bypass, but other types of grafts such as polytetrafluoroethylene (Teflon), polyethylene terephthalate (Dacron), or a different person's vein (allograft) are also commonly used. (wikipedia.org)
  • We developed a tissue-engineered vascular graft (TEVG) for use in children and present results of a U.S. Food and Drug Administration (FDA)-approved clinical trial evaluating this graft in patients with single-ventricle cardiac anomalies. (stanford.edu)
  • Vascular injury has been seen in patients with acute graft versus host disease (GVHD) in the skin. (nih.gov)
  • Vascular lesions of the hand are common and are distinct from vascular lesions elsewhere because of the terminal vascular network in this region, the frequent hand exposure to trauma and microtrauma, and the superficial location of the lesions. (springer.com)
  • Vascular lesions in the hand may be secondary to local pathology, a proximal source of emboli, or systemic diseases with vascular compromise. (springer.com)
  • The purpose of this article is to describe the state-of-the-art acquisition protocols and illustrate the different patterns of vascular lesions and perivascular tumours of the hand. (springer.com)
  • Vascular lesions of the hand are common and are distinct from vascular lesions elsewhere. (springer.com)
  • Vascular lesions in the hand may be secondary to local pathology (e.g. tumour, malformation, trauma, iatrogenic cause, or drug injection), a proximal source of emboli (e.g. dissections or aneurysms), or systemic diseases with vascular compromise (e.g. rheumatic and vaso-occlusive diseases). (springer.com)
  • Clinical history and direct observation remain the best approach for diagnosis of vascular lesions in the hand. (springer.com)
  • In this article, we will review the relevant vascular anatomy, describe the state-of-the-art acquisition protocols, and illustrate the different patterns of vascular lesions of the hand in adults, while avoiding common diagnostic pitfalls. (springer.com)
  • Limbal papillomas are sessile lesions arising from a broad base with a gelatinous appearance. (medscape.com)
  • Unlike inverted papilloma arising in the lateral nasal wall or paranasal sinuses, lesions arising from the conjunctiva tend to be less aggressive in malignant transformation. (medscape.com)
  • Infantile Hemangiomas Infantile hemangiomas are raised, red or purplish, hyperplastic vascular lesions appearing in the first year of life. (msdmanuals.com)
  • We aim at numerical modeling of atherogenesis based on multiparametric imaging data of vessel architecture, blood flow and vascular inflammation. (uni-muenster.de)
  • These neurological vascular diseases arise from local and systemic inflammation that culminates in vessel wall changes. (thejns.org)
  • Intraoperatively, it is important to be aware of possible vascular anomalies in order to prevent ligation or injury of an essential vessel. (hindawi.com)
  • Resources developed under this FOA must follow open data sharing practices and are intended to expand the broader research community's capacity to perform research aimed at neuropathologically-informed understanding of the vascular pathophysiology of clinically-relevant, in vivo neuroimaging findings. (nih.gov)
  • Subclinical brain magnetic resonance imaging (MRI) findings of presumed vascular origin, such as white matter hyperintensities, and those that have the appearance of infarcts, microbleeds, and microinfarcts are frequently observed in Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementia (ADRD) patients, as well as seemingly healthy older adults. (nih.gov)
  • Despite the frequency of subclinical brain imaging findings of presumed vascular origin, little is known about how they relate to cerebrovascular and other brain pathologies either during life or postmortem. (nih.gov)
  • Frequency and clinical correlates of antiphospholipid antibodies arising in patients with SARS-CoV-2 infection: findings from a multicentre study on 122 cases. (cdc.gov)
  • Does the body imager have to deal with, on a routine or semi-routine basis, breast, neuro-, musculoskeletal, and vascular imaging findings? (medscape.com)
  • The result of this cascade is vascular stasis, hemolysis, and vasoocclusion of the capillary beds. (medscape.com)
  • The rigid sickled erythrocytes lead to vascular occlusion, which results in retinal hypoxia, ischemia, and neovascularization. (medscape.com)
  • Anomalous vascular anatomy during hepaticopancreaticobiliary operations is common. (hindawi.com)
  • We report a case of a patient found to have an anomalous middle colic artery arising from the gastroduodenal artery during a pancreaticoduodenectomy. (hindawi.com)
  • Arteries can also serve as vascular grafts. (wikipedia.org)
  • Dimensional aspects, material selection, and manufacturing methods influence mechanistic behaviours of artificial grafts and chosen to receive artery-like behaviour In the legs, bypass grafting is used to treat peripheral vascular disease, acute limb ischemia, aneurysms and trauma. (wikipedia.org)
  • While there are many anatomical arrangements for vascular bypass grafts in the lower extremities depending on the location of the disease, the principle is the same: to restore blood flow to an area without normal flow. (wikipedia.org)
  • He completed his PhD in biomedical engineering at Yale University as an NSF Graduate Research Fellow, where his dissertation work focused on the design of tissue engineered vascular grafts for use in the Fontan procedure. (stanford.edu)
  • Spontaneous reversal of stenosis in tissue-engineered vascular grafts. (stanford.edu)
  • BACKGROUND: Hand-arm vibration syndrome (HAVS) refers to the neurological, vascular and musculoskeletal problems that may arise due to exposure to segmental vibration to the hands. (cdc.gov)
  • Starting in 2012, the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS) have held research summits triennially to assess research priorities and set research implementation milestones for the ADRDs, which include frontotemporal dementia (FTD), Lewy body dementia (LBD), multiple etiology dementias (MED), and vascular contributions to cognitive impairment and dementia (VCID). (nih.gov)
  • Common bypass sites include the heart (coronary artery bypass surgery) to treat coronary artery disease, and the legs, where lower extremity bypass surgery is used to treat peripheral vascular disease. (wikipedia.org)
  • a "DP" bypass - any vascular bypass where the target is the dorsalis pedis artery on the dorsum of the foot. (wikipedia.org)
  • For coronary and peripheral vascular disease, lack of "runoff" to the distal area is also a contraindication because a vascular bypass around one diseased artery to another diseased area does not solve the vascular problem. (wikipedia.org)
  • For example, supply to the caudate head from the artery of Heubner may arise either as a medial lenticulostriatal perforator or as a direct artery. (ajnr.org)
  • Most common types of dеmеntіа include Alzheimer's disease, vascular and frontotemporal dеmеntіа аnd dеmеntіа wіth Lеwу bоdіеѕ. (selfgrowth.com)
  • The purpose of this Alzheimer's Disease-Related Dementia (ADRD) initiative is to promote the development and distribution of innovative technologies, methods, protocols, and biomedical materials that enhance combined human neuropathology and neuroimaging research with data aimed at understanding the underlying pathophysiology of in vivo imaging results typically associated with vascular contributions to cognitive impairment and dementia (VCID) in TBI-related dementia and other ADRD diagnoses. (nih.gov)
  • Cerebral "microvascular" disease occurs in lacunar stroke, leukoaraiosis, vascular dementia and Alzheimer's disease. (sinapse.ac.uk)
  • This case report describes an extremely rare vascular anomaly encountered during a pancreaticoduodenectomy (Whipple operation). (hindawi.com)
  • It may occur with vascular disease, retinal dystrophy, uveitis, and usage of certain medications. (aao.org)
  • CME arises from the accumulation of fluid within the retina when there is disruption of the normal blood-retinal barrier and abnormal permeability of the perifoveal retinal capillaries. (aao.org)
  • These include cardio-vascular diseases, motor neuron disease, multiple sclerosis, muscular atrophy and numerous others. (ndtv.com)
  • With pulmonary arterial hypertension, the malfunctioning of the vascular epithelium results in the contraction and narrowing of the blood vessels. (medicalnewstoday.com)
  • Such restrictive use of the term "lacunae" ignores the variability in vascular supply throughout the brain. (ajnr.org)
  • Arise uses a third-party service, Google Analytics, to collect standard internet log information and details of behavior patterns for visitors of our website. (arisevascular.com)
  • Aim To test predictions of different large-scale biodiversity hypotheses by analysing species richness patterns of vascular plants in the Austrian Alps.Location The Austrian part of the Alps (c. 53,500 km2).Methods Within the floristic inventory of Central Europe the Austrian part of the Alps were systematically mapped for vascular plants. (researchgate.net)
  • Some vascular tumours preferentially affect the hand, such as pyogenic granulomas or spindle cell haemangiomas associated with Maffucci syndrome. (springer.com)
  • It is commonly performed due to inadequate blood flow (ischemia) caused by atherosclerosis, as a part of organ transplantation, or for vascular access in hemodialysis. (wikipedia.org)
  • Most vascular pathologies arise from atherosclerosis. (uni-muenster.de)
  • The work of my small laboratory in the national program for prevention of mental retardation by early diagnosis of congenital hypothyroidism, and finally screening of early markers of initial stages of dementia en elderly people. (bvsalud.org)
  • He has over 25 years of experience as a vascular surgeon. (acsh.org)
  • Conditions such as melanotic macules , nevi, smoker's melanosis , amalgam and graphite tattoos, racial pigmentation , and vascular blood-related pigments occur with some frequency. (medscape.com)
  • Although extremely rare, other vascular anomalies in this region do occur. (hindawi.com)
  • It underscores the importance of being aware that vascular anomalies in this area occur. (hindawi.com)
  • Here, analysis of umbilical cords from humans and other mammals identified differential arterial-venous proteoglycan dynamics as a determinant of these contrasting vascular responses. (stanford.edu)
  • Pulmonary arterial hypertension (PAH) is a progressive disease characterized by lung endothelial cell dysfunction and vascular remodeling. (surrey.ac.uk)
  • These complications include the permanent and irreversible changes in the Vascular system, nervous system, Genito-urinary system and in the eye. (who.int)
  • In the longer term additional complications may arise as a result of dysfunction and failure in many organ systems. (who.int)
  • COVID-19, neutrophil extracellular traps and vascular complications in obstetric practice. (cdc.gov)
  • CTEPH is thought to result from single or recurrent pulmonary thromboemboli arising from sites of venous thrombosis 1 . (ersjournals.com)
  • In two mitochondrial disease models, hypoxia corrects defects that arise as a consequence of the genetic lesion. (fightaging.org)
  • 1.1 Purpose- This guide establishes recommendations and considerations for the development, verification, validation, and reporting of structural finite element models used in the evaluation of the performance of a metallic vascular stent design undergoing uniform radial loading. (astm.org)
  • Potential triggers, of which there are many, range from the biochemical to neuromuscular and vascular problems, often arising from structural distortions and other stressors. (nwhn.org)
  • Dogma in vascular bypass technique says to obtain proximal and distal control. (wikipedia.org)
  • The injecting of illicit drugs is associated with skin and soft tissue infections (SSTIs) and vascular disease ( 1 - 3 ). (cdc.gov)
  • In the experimental autoimmune encephalitis model of multiple sclerosis , continuous 10% oxygen promotes vascular integrity and apoptosis of infiltrating leukocytes . (fightaging.org)
  • It may arise from or contribute to insidious damage to the blood-brain barrier (BBB). (sinapse.ac.uk)
  • other pregnancy related-problems may arise. (mambaby.com)
  • Problems only arise when they become enlarged. (mambaby.com)
  • It doesn't, until problems arise and mistakes are made. (medscape.com)
  • These include fibroblast growth factors (FGFs), platelet derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). (ihcworld.com)
  • When compared with assuming no change in CMRO 2 , this approach resulted in significantly lower M -values in both visual and motor cortices, arising from significant dose-dependent hypercapnia reductions in basal CMRO 2 of 1.5 ± 0.6%/mmHg (visual) and 1.8 ± 0.7%/mmHg (motor), where mmHg is the unit change in end-tidal CO 2 level. (frontiersin.org)
  • Thus, COVID-19 is deemed as a (micro)vascular and endothelial disease. (nature.com)
  • CONCLUSIONS: This case illustrates a condition descriptively termed 'vibration-white foot': a disease analogous to HAVS arising after segmental vibration exposure to the feet. (cdc.gov)
  • We aimed to identify emerging trends in hospital admission for SSTIs and vascular disease arising from drug use and, specifically, where these may have occurred after injection of the femoral vein. (cdc.gov)
  • Although the number of opiate injecting drug users may have increased in the 1990s ( 8 ), the rapid and substantial increase in admissions for SSTIs and vascular disease suggests that this has not resulted from an increase in the injecting population alone. (cdc.gov)
  • Among the descriptors of heterogeneity, edaphic and land-use heterogeneity are more closely correlated with species numbers than topographic heterogeneity.Main conclusions The results support energy-driven processes as primary determinants of vascular plant species richness in temperate mountains. (researchgate.net)
  • Increased vascular resistance results in right heart strain and remodelling. (ersjournals.com)
  • The results, according to researchers, shed light on various important health issues which arise from living a sedentary lifestyle . (ndtv.com)
  • Oral melanomas are uncommon (1.2 cases per 10 million population per year in the United States), and, similar to their cutaneous counterparts, they are thought to arise primarily from melanocytes in the basal layer of the squamous mucosa. (medscape.com)
  • We aimed to see whether vascular injury mediated by cytotoxic T lymphocytes and microvessel loss arises in patients with chronic GVHD. (nih.gov)
  • Manual of vascular plants of northeastern United States and adjacent Canada. (swbiodiversity.org)
  • Also remarkable is the rise to dominance of vascular plants. (britannica.com)
  • Pigmented entities are relatively common in the oral mucosa and arise from intrinsic and extrinsic sources. (medscape.com)
  • Mice lacking aggrecan or the metalloprotease ADAMTS1, which degrades proteoglycans, demonstrate their opposing roles in umbilical vascular dimorphism, including effects on SMC differentiation. (stanford.edu)
  • Vascular conditions affect not only your arms, legs and feet, but your daily life. (mercy.net)
  • And they do more than surgery: they take the time to educate you on vascular health issues and treatment options and invite you to be an active partner in determining the care plan that's best for you. (mercy.net)
  • Nestin was also observed in some vascular cells, as demonstrated by the co-immunoreactivity of the protein with vWF in the choroid and retina. (molvis.org)
  • Induced EndoMT cells exhibited up-regulation of mesenchymal markers, including collagen type I and α-smooth muscle actin, and a reduction in endothelial cell and junctional proteins, including von Willebrand factor, CD31, occludin, and vascular endothelial-cadherin. (surrey.ac.uk)
  • A vascular bypass is a surgical procedure performed to redirect blood flow from one area to another by reconnecting blood vessels. (wikipedia.org)
  • On web sites that Arise does not control, we cannot be responsible for the privacy of any information collected, directly or indirectly. (arisevascular.com)