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  • liquid chromatograp
  • Basal and A23187-stimulated release of 15-, 5-, and 12-hydroxyeicosatetraenoic acids (HETEs) from females and males were measured by liquid chromatography/mass spectrometry. (ahajournals.org)
  • secretion
  • Preincubation of resident peritoneal macrophages with 10-100 ng/ml LPS for 60 min resulted in the cells becoming primed for enhanced (three-to eightfold higher) arachidonic acid (20:4) secretion in response to a variety of triggers. (rupress.org)
  • Our previous data suggested that lipoxygenation of endogenously released arachidonic acid (AA) is a critical step in stimulus-secretion coupling in the pancreatic beta cell. (diabetesjournals.org)
  • However, the unstable intermediate 12-hydroperoxyei-cosatetraenoic acid (12-HPETE), and positional isomers of 12-HPETE, potentiated glucose-induced insulin secretion. (diabetesjournals.org)
  • membrane
  • Arachidonic acid is stored within the cell membrane, and is responsible for signaling adaptive changes in the response to muscle damage and related stimuli. (steroid.com)
  • lipid
  • In addition to being involved in cellular signaling as a lipid second messenger involved in the regulation of signaling enzymes, such as PLC -γ, PLC-δ, and PKC -α, -β, and -γ isoforms, arachidonic acid is a key inflammatory intermediate and can also act as a vasodilator . (wikipedia.org)
  • schmuckeri microorganisms or lipid isolated from such microorganisms to enhance the arachidonic acid content of the food product. (patents.com)
  • stimulation
  • The presence of a second inducible form of COX was first suggested by experiments, which showed a transient increase in the formation of PGE 2 from arachidonic acid by canine kidney cells upon stimulation with tumor promoters and carcinogens [ 5 , 6 ]. (mdpi.com)