AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, AgricultureInformation ScienceHealth Care
DNA GlycosylasesArabidopsisArabidopsis ProteinsN-Glycosyl HydrolasesGene Expression Regulation, PlantDNA-Formamidopyrimidine GlycosylaseDeoxyribonuclease (Pyrimidine Dimer)Uracil-DNA GlycosidaseThymine DNA GlycosylaseGenes, PlantDNA RepairPlants, Genetically ModifiedDNA-(Apurinic or Apyrimidinic Site) LyaseHydantoinsMolecular Sequence DataPlant RootsPentoxylUracilPlant ProteinsMutationRNA, PlantPlant LeavesDeoxyribonuclease IV (Phage T4-Induced)Carbon-Oxygen LyasesSeedlingFlowersAmino Acid SequenceDNA, PlantGuanineEndodeoxyribonucleasesSeedsDNA DamageMethanococcalesAlkylationBase SequenceCytosineSequence Homology, Amino AcidThymineIndoleacetic AcidsGenome, PlantSubstrate SpecificityGerminationPlant Growth RegulatorsDNASequence AlignmentEscherichia coliPlant ShootsMeristemAbscisic AcidOxylipinsPlant DiseasesPhenotypePlant EpidermisSalicylic Acid5-MethylcytosineHypoxanthineBase Pair MismatchEthylenesCyclopentanesPhylogenyAdenineGenetic Complementation TestCotyledonChloroplastsLightCloning, MolecularEscherichia coli ProteinsMutagenesis, InsertionalPlastidsHypocotylPseudomonas syringaeDNA Polymerase betaPlant StomataProtein Structure, TertiaryGlucosinolatesBrassicaceaeChromosomes, PlantMADS Domain ProteinsOxidation-ReductionCytokininsModels, MolecularPollenKineticsGibberellinsOryza sativaMultigene FamilyPlant StemsTobaccoPlant ImmunityDNA, ComplementaryEcotypePlant Vascular BundleGene Expression ProfilingTranscription FactorsBinding SitesDNA, BacterialProtein BindingPhotoperiodOligodeoxyribonucleotidesChlorophyll
LyaseGenesROS1Transcriptionally activeSpeciesDemethylationMoleculeEpigenetics2018InterproscanRegulatesMethylation levelsCytosine methylationGenomicPolymeraseEvolutionTranscriptionGossypiumProteinsCompoundsDemethylaseChromatinTranslocationRegulateGenomeReplicationEnzymeOrganismsCleavageActivityBindsSynthesisIdenticalOriginDomainGene expressionRepairModificationAnalysisSerum
Lyase2
  • In epigenetics, Zhu's lab discovered the Arabidopsis 5-methylcytosine DNA glycosylase/lyase ROS1 in 2002. (wikipedia.org)
  • This overall reduced methylation levels of A subgenome in natural A. suecica may be related to upregulation of ROS1 (encoding DNA glycosylase/AP lyase) expression. (nature.com)
Genes7
  • Using DNAdemethylase genes sequence of Arabidopsis as reference, 25 DNA demethylase genes were identified in cotton byBLAST analysis. (zbook.org)
  • Forthe analysis of the conserved domain, it was known that the DNA demethylase family gene member has anendonuclease III (ENDO3c) domain.Conclusion: The genes of the DNA demethylase family are distributed differently in different cotton species, and thegene structure is very different. (zbook.org)
  • Under salt stress conditions, Arabidopsis lines expressing VuWRKY21 or VuWRKY87 showed elevated expression of genes participating in saline stress response pathways and reduced oxidative stress induced by reactive oxygen species (ROS). (mdpi.com)
  • Among the salt-responsive genes in Arabidopsis , AtP5CS1 , AtNHX1 , AtRD29A , AtSOS3 , AtSOS2 , and AtSOS1 exhibited modulated expression levels after stress imposition. (mdpi.com)
  • These findings suggest that the expression of both VuWRKY genes in Arabidopsis , particularly VuWRKY21 , activated genes involved in salinity tolerance. (mdpi.com)
  • Alterations in DNA methylation, lncRNAs and multiple genes may be involved in the regulation of FTLs . (nature.com)
  • Cis-acting DNA sequences which can increase transcription of genes. (lookformedical.com)
ROS12
  • ROS1 is the first DNA demethylase (the enzyme initiating active DNA demethylation) established with genetic and biochemical evidence. (wikipedia.org)
  • From the phylogenetic tree analysis,the DNA demethylase gene family of cotton can be divided into four subfamilies: REPRESSOR of SILENCING 1 (ROS1),DEMETER (DME), DEMETER-LIKE 2 (DML2), and DEMETER-LIKE3 (DML3). (zbook.org)
Transcriptionally active1
  • Programmed genome rearrangements in Oxytricha produce transcriptionally active extrachromosomal circular DNA. (shengsci.com)
Species2
  • The sequence similarity of DNA demethylasegenes in the same species was higher, and the genetic relationship was also relatively close. (zbook.org)
  • Among transposable elements, LTR retrotransposons tend to be more active ( younger insertion events ) in the T subgenome of A. suecica than in A. thaliana species. (nature.com)
Demethylation1
  • Themode and level of DNA methylation depend on the roles of DNA methyltransferase and demethylase, while DNAdemethylase plays a key role in the process of DNA demethylation. (zbook.org)
Molecule2
  • Single-molecule kinetics reveal microscopic mechanism by which High-Mobility Group B proteins alter DNA flexibility. (shengsci.com)
  • We developed a new single-molecule method to probe non-specific DNA interactions for two HMGB homologs: the human HMGB2 box A domain and yeast Nhp6Ap, along with chimeric mutants replacin. (shengsci.com)
Epigenetics3
  • Epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence. (ac.ir)
  • Epigenetics of a tandem DNA repeat: chromatin DNaseI sensitivity and opposite methylation changes in cancers. (shengsci.com)
  • Our catalog antibodies can be used in popular research areas including epigenetics, DNA damage/repair, cancer, and immunology. (abclonal.com)
20181
  • 2018). DNA methylationis regulated by different pathways to establish methylation and reverse methylation (Ja and Se 2010). (zbook.org)
Interproscan2
  • ARID DNA-binding domain [Interproscan]. (ntu.edu.sg)
  • DNA polymerase, Y-family, little finger domain [Interproscan]. (ntu.edu.sg)
Regulates2
  • Journal of Cotton Research(2019) RCHJournal of Cotton ResearchOpen AccessGenome-wide identification and expressionanalysis of DNA demethylase family incottonYANG Xiaomin, LU Xuke, CHEN Xiugui, WANG Delong, WANG Junjuan, WANG Shuai, GUO Lixue, CHEN Chao,WANG Xiaoge, WANG Xinlei and YE Wuwei*AbstractBackground: DNA methylation is an important epigenetic factor that maintains and regulates gene expression. (zbook.org)
  • Our data provided a landscape of the transcriptome and DNA methylome and revealed a candidate network that regulates flowering time in pineapple, which may promote further studies. (nature.com)
Methylation levels1
Cytosine methylation2
  • Individual variation in size and fecundity is correlated with differences in global DNA cytosine methylation in the perennial herb Helleborusfoetidus (Ranunculaceae). (ac.ir)
  • Plants have evolved a complex transcriptional machinery for generating and using small RNAs that guide DNA cytosine methylation at homologous regions of the genome. (biomedcentral.com)
Genomic3
  • This study identified the cotton DNA demethylasegene family and analyzed it using bioinformatics methods to lay the foundation for further study of cottondemethylase gene function.Results: This study used genomic information from diploid Gossypium raimondii JGI (D), Gossypium arboreum L. CRI(A), Gossypium hirsutum L. JGI (AD1) and Gossypium barbadebse L. NAU (AD2) to Arabidopsis thaliana. (zbook.org)
  • Pol IV is needed to produce the small RNA trigger for methylation whereas Pol V acts downstream of small RNA biogenesis to facilitate de novo methylation of genomic DNA at the small RNA-targeted site. (biomedcentral.com)
  • Indeed, these balanced genomic diversities are accompanied by pervasive convergent and concerted changes in DNA methylation and gene expression among allotetraploids. (nature.com)
Polymerase2
  • Key components of the RNA-directed DNA methylation pathway include two functionally diversified RNA polymerase II (Pol II)-related RNA polymerases called Pol IV and Pol V [ 1 ]. (biomedcentral.com)
  • DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. (lookformedical.com)
Evolution1
  • The gene structure and evolution were analyzed by bioinformatics, and the expressionpatterns of DNA demethylase gene family in Gossypium hirsutum L. were analyzed. (zbook.org)
Transcription2
  • Eukaryotic High-Mobility Group B (HMGB) proteins alter DNA elasticity while facilitating transcription, replication and DNA repair. (shengsci.com)
  • The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION. (lookformedical.com)
Gossypium1
  • However, in other allopolyploids such as Arabidopsis suecica , Upland cotton ( Gossypium hirsutum ) or Pima cotton ( G. barbadense ) 3 , the genomes coexist relatively stable, although changes can occur at levels of gene expression and epigenetic modifications. (nature.com)
Proteins4
  • The microstructure (not code) of DNA itself or the associated chromatin proteins may be modified, causing activation or silencing. (ac.ir)
  • A method for determining the sequence specificity of DNA-binding proteins. (lookformedical.com)
  • Proteins which bind to DNA. (lookformedical.com)
  • The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases. (lookformedical.com)
Compounds1
  • Hydrolases, Glycosylases, Hydrolyzing N-glycosyl compounds. (uma.es)
Demethylase1
  • Analysis of the genestructure revealed that the DNA demethylase gene family members of the four subfamilies varied greatly. (zbook.org)
Chromatin1
  • DNA methylation and chromatin DNaseI sensitivity were analyzed in and adjacent to D4Z4 repeat arrays, which consist of 1 to approximately 100 tandem 3.3-kb units at subtelomeric 4q and 10q. (shengsci.com)
Translocation2
  • Iron deficiency in barley plants: Phytosiderophore release, iron translocation, and DNA methylation. (ac.ir)
  • Extrachromosomal circular DNA (eccDNA) is both a driver of eukaryotic genome instability and a product of programmed genome rearrangements, but its extent had not been surveyed in Oxytricha, a ciliate with elaborate DNA elimination and translocation during development. (shengsci.com)
Regulate1
  • 16. Borsani O, Zhu J, Verslues P E, Sunkar R, Zhu J K, Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis. (sustech.edu.cn)
Genome1
  • Here, we integrated isoform sequencing (iso-seq), Illumina short-reads sequencing and whole-genome bisulfite sequencing (WGBS) to explore the early changes of transcriptomic and DNA methylation in pineapple following high-concentration ethylene (HE) and low-concentration ethylene (LE) treatment. (nature.com)
Replication2
  • The maintenance activities of METHYLTRANSFERASE1 (MET1) and CHROMOMETHYLASE3 act primarily to perpetuate pre-existing CG and CHG methylation, respectively, during successive rounds of DNA replication [ 7 ]. (biomedcentral.com)
  • We describe an improved model of DNA replication in Xenopus egg extracts, in which a circular plasmid immobilized on paramagnetic beads is used as a template. (shengsci.com)
Enzyme2
  • An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. (lookformedical.com)
  • The enzyme has a preference for double-stranded DNA. (lookformedical.com)
Organisms2
  • 2013). DNA methylation is a necessary setup for the normal growth and development of organisms. (zbook.org)
  • Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. (lookformedical.com)
Cleavage2
Activity2
  • In addition, DNA repair enzymes enhance your Skin's recovery and encourages cellular activity to aid in cell repair. (avantiaesthetics.co.uk)
  • This skin restorer promotes collagen production, uses DNA repair enzymes to enhance your skin's recovery capabilities and encourages cellular activity to aid in skin cell repair. (avantiaesthetics.co.uk)
Binds1
  • A cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis. (lookformedical.com)
Synthesis2
  • DNA synthesis occurred on either circular or linear plasmids coupled to the beads, but only DNA synthesis on the circular plasmid was inhibited by geminin and a. (shengsci.com)
  • Their binding to DNA inhibits synthesis of nucleic acids. (lookformedical.com)
Identical1
  • The newly assembled T subgenome of neo-allotetraploids is almost identical to the published A. thaliana L er sequence, and A subgenome is closely related to the A. arenosa sequence. (nature.com)
Origin1
  • The amount of homoeologous exchanges between two subgenomes in Allo738 is relatively small, only ~21.5 kb of the A. thaliana origin in the A subgenome and ~1.4 Mb of the A. arenosa origin in the T subgenome. (nature.com)
Domain1
  • The results showed that the plant's DNAdemethylase all contained conserved DNA glycosidase domain. (zbook.org)
Gene expression1
Repair2
Modification1
  • RNA-directed DNA methylation results in a characteristic modification pattern that is typified by methylation of cytosines in all sequence contexts (CG, CHG and CHH, where H is A, T or C) within the region of small RNA-DNA sequence homology [ 4 ]. (biomedcentral.com)
Analysis1
  • We performed a methylation-sensitive amplification polymorphism analysis to search for targets of RNA-directed DNA methylation in Arabidopsis thaliana and identified several members of a gene family encoding cysteine-rich peptides (CRPs). (biomedcentral.com)
Serum1
  • The special enzymes in this daily defense serum attach directly to your own DNA molecules, repairing oxidative damage such as skin pigmentation caused by UV exposure. (avantiaesthetics.co.uk)