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  • 2016
  • Bellati J , Champeyroux C , Hem S , Rofidal V , Krouk G , Maurel C , Santoni V ✉ (2016) Novel aquaporin regulatory mechanisms revealed by interactomics . (inra.fr)
  • Afzal Z, Howton TC, Sun Y, Mukhtar MS (2016) The roles of aquaporins in plant stress responses. (springer.com)
  • inhibitors
  • Future research on renal water transport will focus on the search for other aquaporins, structure-function relationship of aquaporins, the development of aquaporin inhibitors and their possible use as diuretics, and further elucidation of the renal vasopressin pathway. (springer.com)
  • This perceived importance contrasts with the lack of success of high-throughput screens (HTS) to identify effective and specific inhibitors of aquaporins. (mdpi.com)
  • aquaglyceroporins
  • AQP 11 and 12 appear to be more distantly related to the other mammalian aquaporins and aquaglyceroporins. (ebi.ac.uk)
  • In addition, MD simulation results suggest that AqpM combines characteristics of strict aquaporins, such as the narrow SF and channel radius, with those of aquaglyceroporins, such as a more hydrophobic and less polar SF. (ebscohost.com)
  • stomatal
  • Rodrigues O , Reshetnyak G , Grondin A , Saijo Y, Leonhardt N, Maurel C , Verdoucq L ✉ (2017) Aquaporins facilitate hydrogen peroxide entry into guard cells to mediate ABA- and pathogen-triggered stomatal closure . (inra.fr)
  • Overexpression
  • Findings show that overexpression of aquaporin 5 (AQP5 ) activated epithelial-mesenchymal transition ( EMT (show ITK Antibodies )) in colorectal cancer ( CRC (show CALR Antibodies )) cells. (antibodies-online.com)
  • Tumor
  • J. E. Towne, C. M. Krane, C. J. Bachurski, and A. G. Menon, "Tumor necrosis factor- α inhibits aquaporin 5 expression in mouse lung epithelial cells," The Journal of Biological Chemistry , vol. 276, no. 22, pp. 18657-18664, 2001. (hindawi.com)
  • By closing these aquaporins, tumor growth and metastases could be inhibited. (innovations-report.com)
  • expression
  • Abdelkader AF, El-khawas S, El-Din El-Sherif NA, Hassanein RA, Emam MA, Hassan RE (2012) Expression of aquaporin gene (OsPIP1-3) in salt-stressed rice ( Oryza sativa L.) plants pre-treated with the neurotransmitter (dopamine). (springer.com)
  • Bellemere G, Von Stetten O, Oddos T (2008) Retinoic acid increases aquaporin 3 expression in normal human skin. (springer.com)
  • Tanshinone IIA ameliorates seawater exposure-induced lung injury by inhibiting aquaporins (AQP) 1 and AQP5 expression in lung," Respiratory Physiology and Neurobiology , vol. 176, no. 1-2, pp. 39-49, 2011. (hindawi.com)
  • Novel
  • Conclusions: MD simulations of AqpM extend previous evidence that this archaeal aquaporin exhibits hybrid features intermediate between the two known aquaporin sub-families, supporting the idea that it may constitute a member of a novel class of aquaporins. (ebscohost.com)
  • variants
  • Even though there are different variants of aquaporin, they are all similar and work in largely the same way. (innovations-report.com)
  • Because there are many other variants of aquaporins throughout the body, Lennon suggests that these proteins might play a role in poorly understood autoimmune disorders in other organ systems. (rxpgnews.com)
  • yeast
  • We have used yeast fungi to produce aquaporins," says Per Kjellbom. (innovations-report.com)
  • see the Perspective by Abramson and Vartanian ) describe the subangstrom resolution structure of yeast aquaporin, which allows assignment of side-chain conformations and shows that the H-bond geometry of water molecules prevents proton conductance without compromising water transport. (sciencemag.org)
  • Here, we present the crystal structure of a yeast aquaporin at 0.88 angstrom resolution. (sciencemag.org)
  • redistribution
  • Wudick MM , Li X, Valentini V , Geldner N, Chory J, Lin J, Maurel C ✉, Luu D-T ✉ (2015) Sub-cellular redistribution of root aquaporins induced by hydrogen peroxide . (inra.fr)