• Aquaporin 3 (AQP-3) is the protein product of the human AQP3 gene. (wikipedia.org)
  • 수분통로단백질인 aquaporin 3 (AQP3)은 백반증, 건선 등 다양한 피부 관련 질병의 발현에 중요한 역할을 한다. (e-ajbc.org)
  • Aquaporin 3 (AQP3) plays an important role in the expression of various skin-related diseases such as vitiligo and psoriasis. (e-ajbc.org)
  • the staining score was defined as sum of these scores used to categorize the AQP3 expression as negative (0 through 2), weak (3 through 5) or strong (6 or more). (dsmc.or.kr)
  • However, only aquaporin-3 (AQP3), a member of the aquaporin family, showed significantly higher levels in the CBD-treated group than in the control group at both the mRNA and protein levels. (layv.co)
  • Aquaporin-3 (AQP3) is a membrane protein that contributes to the water homeostasis of the epidermis, and decreased AQP3 expression following ultraviolet (UV)-irradiation of the skin is associated with reduced skin moisture. (kyobobook.co.kr)
  • Background Aquaporin 3 (AQP3) and Cellular-mesenchymal to epithelial transition factor (c-Met) are both overexpressed in human breast cancer and highly related to proliferation and migration. (scite.ai)
  • Expression and function of aquaporins in human skin: Is aquaporin-3 just a glycerol transporter? (edu.sa)
  • Dive into the research topics of 'Expression and function of aquaporins in human skin: Is aquaporin-3 just a glycerol transporter? (edu.sa)
  • Such responses include aquaporin-3, which allows the transportation of water and glycerol involved in the maintenance of epidermal hydration. (clariant.com)
  • Aquaporin-9 Protein Is the Primary Route of Hepatocyte Glycerol Uptake for Glycerol Gluconeogenesis in Mice. (lu.se)
  • Triglycerides are lipid compounds composed of a glycerol esterified to 3 fatty acid chains of varying length and composition. (medscape.com)
  • Although NOD-like receptor protein 3 (NLRP3) inflammasome activation is known to. (koreamed.org)
  • The encoded protein is the predominant aquaporin found in brain. (antibodies-online.com)
  • Aquaporin 1 is a 28-kD integral protein thought at first to be a breakdown product of the Rh polypeptide but was later shown to be a unique molecule that is abundant in erythrocytes and renal tubules. (ihcworld.com)
  • Li XJ, Xiang Y, Ma B and Qi XQ: Effects of acetazolamide combined with or without NaHCO 3 on suppressing neoplasm growth, metastasis and aquaporin-1 (AQP1) protein expression. (spandidos-publications.com)
  • Purification and characterization of two protein kinases acting on the aquaporin SoPIP2;1. (lu.se)
  • In neuromyelitis optica spectrum disorder, the immune system targets aquaporin 4, a protein that is present on astrocytes in the brain and particularly the spinal cord and optic nerves, or myelin oligodendrocyte glycoprotein (MOG), which is present on the myelin of oligodendrocytes in the same areas of the CNS and possibly other targets. (msdmanuals.com)
  • Nephrogenic DI arises from defective or absent receptor sites at the cortical collecting duct segment of the nephron (X-linked, vasopressin V2 receptor deficiency, locus Xq28) or defective or absent aquaporin, the protein that transports water at the collecting duct (autosomal recessive, locus 12q13). (medscape.com)
  • It should be noted that the protein aquaporin-1 is a water channel expressed in the proximal tubule and in the thin descending loop of Henle and is not regulated by vasopressin. (medscape.com)
  • Through a G protein-adenylate cyclase coupling, activation of the ADH receptor increases cyclic adenosine monophosphate (cAMP) production and stimulates protein kinase A, leading to increased recycling of the protein aquaporin in the plasma membrane. (medscape.com)
  • Perilipin 1 binds to aquaporin 7 in human adipocytes and controls its mobility via protein kinase A mediated phosphorylation. (lu.se)
  • This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and membrane transport systems, also allowing permeation of NO and hydrogen peroxide, a major ROS, in oxidative stress physiology and pathophysiology. (hindawi.com)
  • This notion has been challenged by the discovery of new membrane transport functions, especially those exerted by aquaporins (AQPs), a family of membrane channel proteins widespread in nature [ 10 , 11 ]. (hindawi.com)
  • Background/Aim: Recent studies have revealed aquaporins (AQPs) as targets for novel anti-tumor therapy since they are likely to play a role in carcinogenesis, tumor progression and invasion. (dsmc.or.kr)
  • The aquaporins (AQPs) are a family of transmembrane proteins forming water channels. (edu.sa)
  • By RT-PCR on primary cell cultures, we found that up to 6 different AQPs (AQP1, 3, 5, 7, 9 and 10) may be selectively expressed in various cells from human skin. (edu.sa)
  • Aquaporins (AQPs) facilitate transport of water and small solutes across cell membranes and play an important role in different physiological processes in plants. (biomedcentral.com)
  • Aquaporins (AQPs) are small (21-34 kD) integral membrane proteins, which form channels facilitating movement of water and other small solutes across the cell membrane. (biomedcentral.com)
  • Suberoylanilide hydroxamic acid (SAHA) (a HDAC inhibitor) increases expression of aquaporin-3 in normal skin cells (keratinocytes). (wikipedia.org)
  • 2012. Expression of aquaporin 3 in gills of the Atlantic killifish (Fundulus heteroclitus): Effects of seawater acclimation. (nih.gov)
  • In the presence of ADH stimulus, exocytic insertion of aquaporin into the apical, or luminal, surface of the tubule cell occurs. (medscape.com)
  • Product Description specifical Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to AQP-3. (biobool.com)
  • Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for AQP-3 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. (biobool.com)
  • Only those wells that contain AQP-3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. (biobool.com)
  • In the kidney, aquaproin-3 is unresponsive to the antidiuretic hormone vasopressin, unlike aquaporin-2. (wikipedia.org)
  • [6] . Others have shown a similar change in paracellular permeability regulated by AQP5 in salivary glands, however in that system it was associated with alterations in claudin-7, claudin-3, and occludin [5] . (plos.org)
  • The association of Intron 4 VNTR and Glu298Asp polymorphisms of the nitric oxide synthetase 3 gene and vasculogenic erectile dysfunction in Turkish men. (cdc.gov)
  • Increasing gene dosage greatly enhances recombinant expression of aquaporins in Pichia pastoris. (lu.se)
  • Unexpected complexity of the Aquaporin gene family in the moss Physcomitrella patens. (lu.se)
  • Structural mechanism of plant aquaporin gating. (lu.se)
  • The canonical function of aquaporin (AQP) water channels is to facilitate passive transport of water across cellular membranes making them essential in the regulation of body water homeostasis . (bvsalud.org)
  • To maintain optimal water levels, Aquaporin water channels facilitate the movement of large amounts of water, transporting it through cell membranes and plasma membranes to ensure our cells have plenty of water, helping to prevent water loss. (charlottetilbury.com)
  • Water is also be transported from the luminal side of cells into the vasculature by aquaporin 3. (drugbank.com)
  • Expression and localization of aquaporins 3 and 7 in bull spermatozoa and their relevance to sperm motility after cryopreservation. (researchmap.jp)
  • Containing two key glycosylated flavonoids directly involved in circadian clock maintenance - carlinoside and isoschaftoside - B-Circadin emulates the ability to resynchronize the circadian cycle within the skin cells, to regulate rhythm-dependent biological functions such as aquaporin-3 and Nrf2 pathway detoxification efficacy. (clariant.com)
  • Igarashi H, Huber VJ, Tsujita M, Nakada T. Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema. (benthamscience.com)
  • it inhibits transcription for genes that encode IL-3, IL-4, IL-5, GM-CSF, and TNF-alpha (all involved in early T-cell activation). (medscape.com)
  • With volunteers working at night, so having their biological rhythms disrupted, a cream containing 3% B-Circadin was applied to one half of the face and a placebo to the other half, for 28 days. (clariant.com)
  • Charlotte's Magic Water Cream , I was introduced to Aquaporin, and I was so excited by the possibilities that this secret ingredient could bring to my beauty innovations. (charlottetilbury.com)
  • however, scientists learnt more about Aquaporin and water transport after recognising its ability to regulate the flow of water. (charlottetilbury.com)
  • Aquaporin-5 (AQP5) is a water-specific channel located on the apical surface of airway epithelial cells. (plos.org)
  • While Lgr5 + cells are long-lived and act as stem cells during homeostatic conditions, experimental models have demonstrated that Lgr5 + stem cells per se are not essential for maintaining epithelial integrity 3 . (nature.com)
  • Water is kept out of cells by lipid bilayers, and so, it relies on Aquaporin water channels to act as an open gateway that allows entry into our cells. (charlottetilbury.com)
  • The most common type of Aquaporin in the skin is Aquaporin-3 which is known to help transport water from the skin's surface into skin cells. (charlottetilbury.com)
  • This has been studied mainly in the small intestine, where different cell types such as enterocyte progenitors 4 , more differentiated secretory Bmi1 + cells 3 , or even fully differentiated Paneth cells can repopulate crypts upon injury. (nature.com)
  • Alternatively, defective or absent aquaporin impairs the process in the presence of normal V2 receptors. (medscape.com)
  • Structure and Stability of the Spinach Aquaporin SoPIP2;1 in Detergent Micelles and Lipid Membranes. (lu.se)
  • Reconstitution of water channel function and 2D-crystallization of human aquaporin 8. (lu.se)
  • International journal of molecular epidemiology and genetics 2021 12 (3): 40-51. (cdc.gov)
  • Aquaporin 3 levels are often lower in psoriasis than in healthy skin. (wikipedia.org)
  • 3 ] found that 74% of T2DM patients had one or more skin problems, with the highest amount being dry skin (47%), followed by infection (10%), diabetic foot (5%), hair loss, and diabetic dermopathy (4%), respectively. (hindawi.com)
  • It leads to decreased expression of IL-3, IL-4, IL-5, and TNFα, and it inhibits mast cell and neutrophil activation. (medscape.com)
  • A 2-year-old child with a history of infantile pre-B cell acute lymphoblastic leukemia (ALL) was admitted to hospital with nausea and vomiting after 3 weeks of upper respiratory tract symptoms. (cdc.gov)
  • Recent studies indicate that aquaporin 3 is overexpressed in many types of malignancies such as melanoma and primary effusion lymphomas as well as cancers of the lung, colon, stomach, esophagus, mouth, liver, and pancreatic duct. (wikipedia.org)
  • Frontiers in Plant Science 2012, 3 . (lu.se)