• Aquaporin 3 (AQP-3) is the protein product of the human AQP3 gene. (wikipedia.org)
  • Aquaporin-3 (AQP3) is a membrane protein that contributes to the water homeostasis of the epidermis, and decreased AQP3 expression following ultraviolet (UV)-irradiation of the skin is associated with reduced skin moisture. (kyobobook.co.kr)
  • No previous study has examined whether the skin-moisturizing effect of MELs might act through the modulation of AQP3 expression. (kyobobook.co.kr)
  • Our results revealed that UVA irradiation decreases AQP3 expression at the protein and messenger RNA (mRNA) levels, but that MEL treatment significantly ameliorated these effects. (kyobobook.co.kr)
  • Our mitogenactivated protein kinase inhibitor analysis revealed that phosphorylation of c-Jun N-terminal kinase (JNK), but not extracellular signal-regulated kinase or p38, mediates UVA-induced AQP3 downregulation, and that MEL treatment significantly suppressed the UVA-induced phosphorylation of JNK. (kyobobook.co.kr)
  • which acts as a potent transcription factor for AQP3 expression. (kyobobook.co.kr)
  • Collectively, our findings suggest that MELs can be used as a potential ingredient that modulates AQP3 expression to improve skin moisturization following UVA irradiation-induced damage. (kyobobook.co.kr)
  • 수분통로단백질인 aquaporin 3 (AQP3)은 백반증, 건선 등 다양한 피부 관련 질병의 발현에 중요한 역할을 한다. (e-ajbc.org)
  • Aquaporin 3 (AQP3) plays an important role in the expression of various skin-related diseases such as vitiligo and psoriasis. (e-ajbc.org)
  • we previously demonstrated that aquaporin 3 (AQP3) is expressed in goblet cells and is positively correlated with GIM severity. (oncotarget.com)
  • However, the relationships of AQP3 with GIM classification and with other proteins, and their roles in the transition from GIM to gastric carcinoma (GC) remain unknown. (oncotarget.com)
  • GIM classification was determined via HID-AB staining, and AQP3, CD24, LGR5 and Ki67 expression were determined by immunohistochemistry. (oncotarget.com)
  • AQP3 expression showed significant correlation to type III GIM. (oncotarget.com)
  • However, only aquaporin-3 (AQP3), a member of the aquaporin family, showed significantly higher levels in the CBD-treated group than in the control group at both the mRNA and protein levels. (layv.co)
  • In addition, it is possible that increased expression of AQP3, which plays an important role in skin water retention, is a contributor to the mechanism. (layv.co)
  • We investigated the metabolism of mouse isolated heart under the influence of tricarbonyldichlorothenium (II)- dimer (CORM-2 and 2,3-4,5-bis-O-isopropylidene-βD-fructopyranose sulfamate (topiramate) as potential blockers of aquaporine channel (AQP3) of cardiac myocytes. (kiev.ua)
  • Various recent studies suggest that membrane channel proteins, named aquaporin (AQPs), by affecting stomatal conductance behavior could be involved in plant responses to stress conditions. (ac.ir)
  • The sunTIP7 gene is a member of AQPs protein that is included in different environmental stress such as drought stress. (ac.ir)
  • مطالعات متعدد اخیر نشان می-دهد که پروتئین-های کانال غشایی به نام Aquaporin (AQPs) با تأثیر بر رفتار هدایت روزنه می- توانند در پاسخ گیاهان به شرایط تنش نقش داشته باشند. (ac.ir)
  • The aquaporins (AQPs) are a family of transmembrane proteins forming water channels. (edu.sa)
  • In the present work, we examined the overall expression of AQPs in cells from human skin and we reviewed data on the functional role of AQPs in skin, particularly in the epidermis. (edu.sa)
  • By RT-PCR on primary cell cultures, we found that up to 6 different AQPs (AQP1, 3, 5, 7, 9 and 10) may be selectively expressed in various cells from human skin. (edu.sa)
  • Choroid plexus epithelial cells (CPECs) secrete most of the CSF through poorly understood mechanisms that involve aquaporins (AQPs) and various solute transport proteins like the Na+-K+-2Cl- cotransporter 1 (NKCC1). (wright.edu)
  • Because of their relatively high transcript expression the present work addresses the cellular and subcellular location of AQPs 4, 7 and 9 proteins in CPECs and EP cells, using immunolabeling with validated antibodies and confocal immunofluorescence. (wright.edu)
  • One of the main traits underlying salt tolerance is the presence of aquaporins (AQPs), a family of proteins that facilitate the movement of water across cell membranes. (botany.one)
  • Aquaporins (AQPs) facilitate transport of water and small solutes across cell membranes and play an important role in different physiological processes in plants. (biomedcentral.com)
  • The present study reports the identification and structural and expression analysis of the AQPs found in the diploid progenitor genomes of A. hypogea i.e. (biomedcentral.com)
  • Phylogenetic analysis showed similar numbers of AQPs clustered in five distinct subfamilies including the plasma membrane intrinsic proteins (PIPs), the tonoplast intrinsic proteins (TIPs), the nodulin 26-like intrinsic proteins (NIPs), the small basic intrinsic proteins (SIPs), and the uncharacterized intrinsic proteins (XIPs). (biomedcentral.com)
  • The global expression profile of AQPs in A. hypogea revealed a similar pattern of AQP expression regardless of the subfamilies or the genomes. (biomedcentral.com)
  • The tissue-specific expression of AQPs suggests an important role in the development and function of the respective organs. (biomedcentral.com)
  • Aquaporins (AQPs) are small (21-34 kD) integral membrane proteins, which form channels facilitating movement of water and other small solutes across the cell membrane. (biomedcentral.com)
  • In primitive land plants, two additional unique classes of AQPs, GlpF-like intrinsic protein (GIPs) and hybrid intrinsic proteins (HIPs) have been described and are presumed to have been lost in the course of evolution [ 12 ]. (biomedcentral.com)
  • This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and membrane transport systems, also allowing permeation of NO and hydrogen peroxide, a major ROS, in oxidative stress physiology and pathophysiology. (hindawi.com)
  • This notion has been challenged by the discovery of new membrane transport functions, especially those exerted by aquaporins (AQPs), a family of membrane channel proteins widespread in nature [ 10 , 11 ]. (hindawi.com)
  • We demonstrate that while Rspo3 from myofibroblasts maintains colonic Lgr5 + cells during homeostasis, during injury its main function is not to maintain Lgr5 + cells but to interact with more differentiated cells that express Lgr4 but not Lgr5 and are able to regain expression of Wnt target genes and generate new crypts. (nature.com)
  • Analysis of the expression profile of CRH-POMC system genes in vitiligo skin biopsies. (igib.res.in)
  • Because many membrane proteins are expressed by multiple species, homologous genes should be tested and screened to identify proteins that are most amenable to crystallization. (the-scientist.com)
  • 3) reported the expression analysis for four possible defence related genes in the E. mallotivara host (zinc finger protein, leucine rich protein, aquaporin and peroxidase), in order to understand the defence mechanisms in papaya. (ijbiotech.com)
  • To identify human PPARs-responsive genes, we established tetracycline-regulated human hepatoblastoma cell lines that can be induced to express each human PPAR and investigated the gene expression profiles of these cells. (biomedcentral.com)
  • Interestingly, it was noted that while ligand-activated PPARδ induced target gene expression, unliganded PPARδ repressed these genes. (biomedcentral.com)
  • The real-time RT-PCR was used to verify the altered expression of selected genes by PPARs and we found that these genes were induced to express in the same pattern as detected in the microarray analyses. (biomedcentral.com)
  • Thus, stress response studies during these growth stages reveal novel differentially regulated genes or proteins with important functions in plant stress adaptation. (intechopen.com)
  • Overexpression of a plasma membrane aquaporin in transgenic tobacco improves plant vigor under favorable growth conditions but not under drought or salt stress. (ac.ir)
  • The challenges of crystallizing membrane proteins-and how they're being overcome Computer artwork of a G protein-coupled receptor in the lipid bilayer of a plasma membrane Medi-Mation Ltd / Photo Researchers Membrane proteins represent only a handful of the total number of protein structures defined to date. (the-scientist.com)
  • Taken together, PI3K/Akt pathways mediate the dDAVP-induced AS160 phosphorylation, and AS160 knockdown is associated with higherAQP2 expression in the plasma membrane. (johnshopkins.edu)
  • Similarly, removing the hydrophilic and flexible ends of a membrane protein can improve crystal formation. (the-scientist.com)
  • Affinity tags can reduce merohedral twinning of membrane protein crystals. (lu.se)
  • Aquaporin-3 in the epidermis: more than skin deep. (kiev.ua)
  • Interested in the mechanism of a CLC chloride transporter protein, they tried to improve the data they obtained from their crystal by replacing a naturally occurring amino acid with a methionine at each of 30 sites in the protein. (the-scientist.com)
  • Molecular mechanism of contractility 17 1.6.3. (fu-berlin.de)
  • Structural mechanism of plant aquaporin gating. (lu.se)
  • CrossRef Ikarashi N, Aburada T, Kon R, Sugiyama K. Water control mechanism of byakkokaninjinto and its active components via aquaporins. (kiev.ua)
  • In the kidney, aquaproin-3 is unresponsive to the antidiuretic hormone vasopressin, unlike aquaporin-2. (wikipedia.org)
  • North WG, Fay MJ, Longo KA, Du J: Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide. (hmdb.ca)
  • Fay MJ, Du J, Yu X, North WG: Evidence for expression of vasopressin V2 receptor mRNA in human lung. (hmdb.ca)
  • Conversely, the phosphoinositide 3-kinase (PI3K) inhibitor LY294002 diminished phosphorylation of Akt (S473) and AS160. (johnshopkins.edu)
  • Protein kinase A (PKA) 7 1.4. (fu-berlin.de)
  • A-kinase anchoring proteins (AKAPs) 9 1.5.1. (fu-berlin.de)
  • Protein kinase A type II activation is sufficient to control the cellular localization of the water channel aquaporin-2 in the kidney 72 3.3.1. (fu-berlin.de)
  • ß-Adrenergic stimulation regulates cardiac contractility through a cyclic adenosine monophosphate (cAMP)- and protein kinase A (PKA)- dependent signaling pathway. (fu-berlin.de)
  • A kinase anchoring proteins (AKAPs) anchor PKA to its substrates and contribute to the specificity of signaling by compartmentalizing PKA and other signaling molecules [Wong, Scott 04]. (fu-berlin.de)
  • In the poster section, Joanna Shisler (University of Illinois at Urbana-Champaign [UIUC], Urbana) reported that the modified virus, Ankara, activates nuclear factor κB through the mitogen-activated protein kinase, extracellular signal–regulated kinase (MEK)/extracellular signal–regulated kinase (ERK) pathway, possibly facilitating the host immune response. (cdc.gov)
  • Li XJ, Xiang Y, Ma B and Qi XQ: Effects of acetazolamide combined with or without NaHCO 3 on suppressing neoplasm growth, metastasis and aquaporin-1 (AQP1) protein expression. (spandidos-publications.com)
  • The expression of AQP1 in the basolateral membrane is a subject of debate. (wright.edu)
  • Program access grant to the STFC Harwell Laser Facility 'The Plant Cell Initiative: Protein interactions in the higher plant secretory pathway' 2017-2021 (approximate value of £200K). (brookes.ac.uk)
  • 2017;312(3):302-13. (kiev.ua)
  • Furthermore, we analysed the 5'-flanking region of the human adipose differentiation-related protein ( adrp ) gene that responded to all subtypes of PPARs. (biomedcentral.com)
  • Consistent with this relatively high divergence among the subtype-specific ligand binding domains, differential activation of PPARs by endogenous and exogenous compounds may account for the specific biological activity of the three PPAR subtypes [ 2 , 3 ]. (biomedcentral.com)
  • Panneerselvam L, Raghunath A, Perumal E. Differential expression of myocardial heat shock proteins in rats acutely exposed to fluoride. (kiev.ua)
  • These survival mechanisms include accumulation of organic osmolytes and increased expression of heat shock proteins through numerous pathways, resulting in osmotolerance. (biomedcentral.com)
  • The response of a plant to drought stress is positively related to physiological traits and gene expression. (ac.ir)
  • In this study in order to investigate the sunTIP7 gene expression and its relation with relative water content (RWC), stomatal conductance, shoot fresh and dry weight, root area, chlorophyll index (SPAD) and electrolyte leakage (EL), six selected sunflower (Helianthus annuus L.) inbred lines were planted in a greenhouse under normal irrigation and water deficit conditions. (ac.ir)
  • Retinol works through these receptors, upturning in gene expression, which increases collagen Type I, III, and IV production and aquaporin -3. (ewalibeauty.com)
  • The developmental gradient in monocot leaves has been exploited to uncover leaf developmental gene expression programs and chloroplast biogenesis processes. (biomedcentral.com)
  • This allows us to generate the first biologically-informed gene expression map of this leaf, with the entire developmental gradient from meristematic to fully differentiated cells captured. (biomedcentral.com)
  • Using a network reconstruction algorithm, we predict that known chloroplast gene expression regulators are differentially involved across those developmental stages. (biomedcentral.com)
  • Beyond this time, no differences in global gene expression in infected and control animals were detectable by microarray analysis. (biomedcentral.com)
  • Whereas in the acute phase of the disease immunoregulatory processes prevail in the hippocampus and the cortex, we observed a strong activation of neurogenic processes in the hippocampal dentate gyrus, both by gene expression and immunohistology starting as early as 3 days after infection. (biomedcentral.com)
  • For this purpose we evaluated the gene expression profile of the two brain structures predominantly affected by brain damage, i.e. the cortex and the hippocampus, at four different stages of the disease in an infant rat model. (biomedcentral.com)
  • Digital gene expression analysis during seedling development of complex traits in winter oilseed rape (Brassica napus L. (uni-giessen.de)
  • A more efficient digital gene expression (DGE) method to produce sequencing data by multiplexing from a large plant population of winter oilseed rape (Brassica napus L.) was created. (uni-giessen.de)
  • The DGE data presented in this study comprise a novel basis for further genetical genomics approaches, e.g. eQTL, gene isolation, functional validation, and development of gene expression markers (GEMs). (uni-giessen.de)
  • Berry intake changes hepatic gene expression and DNA methylation patterns associated with high-fat diet. (lu.se)
  • Aquaporins are multifunctional water and solute transporters highly divergent in living organisms. (benthamscience.com)
  • Activated EGCs and were associated with decrease in tight junction protein occludin and selective water channel aquaporin-3 with a concomitant increase in Claudin-2. (sc.edu)
  • [6] . Others have shown a similar change in paracellular permeability regulated by AQP5 in salivary glands, however in that system it was associated with alterations in claudin-7, claudin-3, and occludin [5] . (plos.org)
  • In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. (thermofisher.com)
  • Here I pursued my scientific interests in subcellular protein localisation, bioinformatics, and mathematical modelling. (brookes.ac.uk)
  • First, we co-expressed fluorescently tagged VAPYRIN with a range of subcellular marker proteins, and secondly, we employed biochemical tools to identify interacting partner proteins of VAPYRIN. (frontiersin.org)
  • The authors conclude by recommending the GhPIP1;1 and GhTIP2;1 aquaporins located on the plasma and vacuolar membranes, respectively, as reliable markers for identification of cotton genotypes tolerant to salt stress. (botany.one)
  • I am committed to interdisciplinary research, and an example of the successes gained from this approach is the project with Prof A Nabok (Engineering Sheffield Hallam University) using total internal reflection ellipsometry to quantify protein-membrane interactions on native plant membranes and human cell lines. (brookes.ac.uk)
  • Structure and Stability of the Spinach Aquaporin SoPIP2;1 in Detergent Micelles and Lipid Membranes. (lu.se)
  • Oxidative stress-induced calreticulin expression and translocation: new insights into the destruction of melanocytes. (igib.res.in)
  • The resulting peroxynitrite generation led to increased oxidative stress that triggered inflammation as shown by increased NLRP-3 inflammasome activation and increased cell death. (sc.edu)
  • Suberoylanilide hydroxamic acid (SAHA) (a HDAC inhibitor) increases expression of aquaporin-3 in normal skin cells (keratinocytes). (wikipedia.org)
  • Igarashi H, Huber VJ, Tsujita M, Nakada T. Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema. (benthamscience.com)
  • The tight junction protein levels were restored following a parallel treatment of GWI mice with a TLR4 inhibitor SsnB and butyric acid that are known to decrease the immunoactivation of EGCs. (sc.edu)
  • Purification and characterization of two protein kinases acting on the aquaporin SoPIP2;1. (lu.se)
  • Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release. (uclouvain.be)
  • The major events in the regulation of the host response on a transcriptional level occur within the first 3 days after infection. (biomedcentral.com)
  • Transcriptional regulation of aquaporins in accessions of Arabidopsis in response to drought stress. (lu.se)
  • AIM OF THE STUDY: This study investigated the efficacy of TFG in a bronchial cell model and an animal model of asthma exacerbation caused by PM. METHODS: BEAS-2B bronchial epithelial cells were simultaneously treated with tumor necrosis factor-α/interleukin (IL)-4 and PM, and the expression of inflammatory cytokines, DNA damage, and autophagy mechanisms were analyzed. (bvsalud.org)
  • In both studies, mechanisms by which AQP5 altered these proteins were not further elucidated. (plos.org)
  • I am a plant cell biologist and protein biochemist at Oxford Brookes University with expertise in the structure and function of the plant endoplasmic reticulum (ER), membrane proteins and auxin biosynthesis using biochemical techniques as well as high-resolution live cell imaging. (brookes.ac.uk)
  • 2000. Hypertonic induction of AQP5 expression through an ERK dependent pathway. (hopkinsmedicine.org)
  • Moreover, siRNA-mediated Akt1 knockdown was associated with unchanged total AS160 but decreased phospho-AS160 expression, indicating that phosphorylation of AS160 is dependent on PI3K/Aktpathways. (johnshopkins.edu)
  • The main aim of our research is to understand the molecular details and physiological roles of the multitude of water channel-like proteins present in plants and animals. (lu.se)
  • Dr. King's research focus early in his tenure was the biology of aquaporin water channel proteins in the respiratory tract as well as other tissues. (hopkinsmedicine.org)
  • Aquaporins in complex tissues: I. Developmental patterns in respiratory tract and glandular tissue of rat. (hopkinsmedicine.org)
  • Aquaporins in complex tissues: II. (hopkinsmedicine.org)
  • Expression and function of aquaporins in human skin: Is aquaporin-3 just a glycerol transporter? (edu.sa)
  • Dive into the research topics of 'Expression and function of aquaporins in human skin: Is aquaporin-3 just a glycerol transporter? (edu.sa)
  • By excising flexible regions of human aquaporin 4, a water channel implicated in the ALS-like autoimmune disease neuromyelitis optica, we obtained a high-resolution structure. (the-scientist.com)
  • Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission. (uclouvain.be)
  • Here, we aimed to study brain dystrophin distribution and expression in both, human and experimental temporal lobe epilepsy (TLE). (frontiersin.org)
  • Reconstitution of water channel function and 2D-crystallization of human aquaporin 8. (lu.se)
  • High-resolution x-ray structure of human aquaporin 5. (lu.se)
  • Large micelles increase the ratio of lipid to protein, making it difficult to pack the protein to a density sufficient for crystal formation. (the-scientist.com)
  • Stevens collaborated with chemists to design new detergents, such as the cholate- based amphiphiles, that create smaller micelles, allowing the protein molecules to pack more closely and form better crystals. (the-scientist.com)
  • Aquaporin-5 (AQP5) is a water-specific channel located on the apical surface of airway epithelial cells. (plos.org)
  • Aquaporin-5 (AQP5) is a water-specific channel located on the apical membrane of epithelial cells in several sites in mammals, including corneal and pancreatic epithelium, secretory cells in salivary and lacrimal glands, and airway submucosal glands, bronchial epithelium and type I pneumocytes of the respiratory tract. (plos.org)
  • Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin-5 (AQP5). (hopkinsmedicine.org)
  • Abnormal distribution of AQP5 water channel protein in salivary glands from Sjgrens syndrome patients. (hopkinsmedicine.org)
  • 3 Researchers can now use high-throughput methods to screen large numbers of expression and purification conditions, which helps to speed the process. (the-scientist.com)
  • Protein expression and purification 44 2.3.4. (fu-berlin.de)
  • Role of aquaporin-4 in cerebral edema and stroke. (benthamscience.com)
  • Vella J, Zammit C, Di Giovanni G, Muscat R, Valentino M. The central role of aquaporins in the pathophysiology of ischemic stroke. (benthamscience.com)
  • Expression of Lgr5 is controlled by Wnt signaling, which plays a critical role for stem cell turnover in the gastrointestinal tract 2 . (nature.com)
  • This study is aimed at investigating the role of dysbiosis associated EGC immune-activation and redox instability in contributing to observed gastrointestinal barrier integrity loss in GWI via altered tight junction protein expression. (sc.edu)
  • I took up a position at Oxford Brookes University in 2012 investigating the role of reticulon proteins in ER tubulation and viral trafficking in order to develop my international reputation in ER research and advanced imaging. (brookes.ac.uk)
  • The present study examined the role of Akt and AS160 in aquaporin-2 (AQP2) trafficking. (johnshopkins.edu)
  • The transcription activators GRF1 (GROWTH REGULATING FACTOR 1), UBP15 (UBIQUITIN-SPECIFIC PROTEASE 15), and VPS2 (VACUOLAR PROTEIN SORTING 2) were found to play a key role in leaf and shoot system development. (uni-giessen.de)
  • In addition to its role in muscle tissue, it functions as an anchoring protein within the central nervous system such as in hippocampus and cerebellum. (frontiersin.org)
  • He also showed that double-stranded (ds)RNA- and ZDNA binding proteins had a role in poxvirus pathogenesis. (cdc.gov)
  • Annotation of Selaginella moellendorffii major intrinsic proteins and the evolution of the protein family in terrestrial plants. (lu.se)
  • Unexpected complexity of the Aquaporin gene family in the moss Physcomitrella patens. (lu.se)
  • The mRNA expression profile of cytokines connected to the regulation of melanocyte functioning in vitiligo skin biopsy samples and peripheral blood mononuclear cells. (igib.res.in)
  • Consistent down regulation of AQP expression was found in salt tolerant genotypes, i.e. those that were able to maintain photosynthetic rates under salt stress. (botany.one)
  • Expression of Aquaporin-1 water channel protein in mouse erythro-leukemia cells: genetic regulation of corticosteroid and chemical induction. (hopkinsmedicine.org)
  • These strategies involve rearrangements at the molecular level starting from transcription, regulation of mRNA processing, translation, and protein modification or its turnover. (intechopen.com)
  • Acutely and chronically, lithium salts produce a natriuresis that is associated with an impaired regulation of the expression of the epithelial sodium channel in the cortical collecting tubule. (medscape.com)
  • Cerebrovasc Dis (2016) 42 (3-4): 155-169. (karger.com)
  • 2016. Isothermal titration calorimetry measurements of metal ions binding to proteins. (nih.gov)
  • Additionally, 4c(2) as an Nrf2 activator could promote the nuclear translocation of Nrf2 protein and induce the expressions of Nrf2-dependent enzymes HO-1, NQO1, and GPX4. (inrae.fr)
  • Chopping off the termini of proteins is a trick long-used to make soluble cytosolic proteins more amenable to crystallization. (the-scientist.com)
  • Takata K, Matsuzaki T, Tajika Y. Aquaporins: water channel proteins of the cell membrane. (benthamscience.com)
  • This has been studied mainly in the small intestine, where different cell types such as enterocyte progenitors 4 , more differentiated secretory Bmi1 + cells 3 , or even fully differentiated Paneth cells can repopulate crypts upon injury. (nature.com)
  • Rspo proteins are secreted and can stabilize the effects of Wnt ligands by preventing ubiquitination and turnover of the Wnt receptor frizzled 9 , thereby dictating the size of the Lgr5 + stem cell pool by regulating self-renewal of Lgr5 + cells 10 . (nature.com)
  • Yet these proteins, which represent nearly 40 percent of all known proteins, including receptors, channels, and signaling molecules, are essential for cell communication and their malfunctions are implicated in many diseases. (the-scientist.com)
  • The volume and quality of proteins produced depends on the organism, cell type, promoter, and vector used to generate them. (the-scientist.com)
  • Of high expression in the skin tissue, aryl hydrocarbon receptor (AhR) is a cytoplasmic protein responsible for maintaining skin homeostasis through proliferation, differentiation, cell arrest and apoptosis signals. (uaslp.mx)
  • We found that the expression of each PPAR subtype was tightly controlled by the concentration of doxycycline in these established cell lines. (biomedcentral.com)
  • To determine the effects of osmolarity/tonicity changes, Wnt/β-catenin and TLR-4 activation on Lcn2-R and Lcn2 expression and cell viability in rat primary IMCD and mouse (m)IMCD3 cells. (biomedcentral.com)
  • ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. (thermofisher.com)
  • However, there was not any clear relationship between physiological traits and expression of sunTIP7 gene in all six sunflower inbred lines. (ac.ir)
  • Aquaporin-9 Protein Is the Primary Route of Hepatocyte Glycerol Uptake for Glycerol Gluconeogenesis in Mice. (lu.se)
  • While Lgr5 + cells are long-lived and act as stem cells during homeostatic conditions, experimental models have demonstrated that Lgr5 + stem cells per se are not essential for maintaining epithelial integrity 3 . (nature.com)
  • Furthermore, it could induce expression of the Nrf2 as well as its downstream markers at the protein level in cells. (inrae.fr)
  • Intracellular establishment of AM fungi requires the VAPYRIN protein which is induced in colonized cells, and which localizes to numerous small mobile structures of unknown identity (Vapyrin-bodies). (frontiersin.org)
  • Substances for treatment of IMCD cells 47 2.5.3. (fu-berlin.de)
  • Hyperosmotic/-tonic media upregulated Lcn2-R by ~4-fold and decreased Lcn2 expression/secretion, along with Wnt/β-catenin activation, in IMCD cells. (biomedcentral.com)
  • 2) AQP 7 expression was found to be restricted to the apical membrane of CPECs and EPCs. (wright.edu)
  • Veterinary Pathology , 52 (3), 465 - 475. (monash.edu)
  • This protein is also a determinant for the GIL blood group system. (wikipedia.org)