This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and membrane transport systems, also allowing permeation of NO and hydrogen peroxide, a major ROS, in oxidative stress physiology and pathophysiology. (hindawi.com)
This notion has been challenged by the discovery of new membrane transport functions, especially those exerted by aquaporins (AQPs), a family of membrane channel proteins widespread in nature [ 10 , 11 ]. (hindawi.com)
Juan Fuentes ABSTRACT Aquaporins (AQPs) are specific transmembrane water channels with an important function in water homeostasis. (silverchair.com)
Membrane2
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. (antibodies-online.com)
Telomerase works the RNA -domain to dependent association of epidermal core lipids to the 3' G-rich heterotrimeric acid membrane. (erik-mill.de)
Abstract1
Steve F. Perry ABSTRACT The present study tested the hypothesis that zebrafish ( Danio rerio ) aquaporin -1a1 (AQP1a1) serves as a multi-functional channel for the transfer of the small gaseous molecules, CO 2 and ammonia, as well as water. (silverchair.com)
Function3
We aim to explore the regulatory mechanism of AQP3 and the function of AQP3 on the skin. (e-ajbc.org)
We summarize the distribution of AQP3 in skin and the regulatory mechanism of AQP3, then point out the function of AQP3 on the skin and the development trend of AQP3 as a new target in the field of cosmetic research. (e-ajbc.org)
A. S. Verkman SUMMARY There is considerable potential for translating knowledge of aquaporin structure, function and physiology to the clinic. (silverchair.com)
Brain2
Ion channel activity has been shown for Aquaporins 0, 1, and 6, Drosophila 'Big Brain' (bib) and plant Nodulin-26. (wikipedia.org)
The encoded protein is the predominant aquaporin found in brain. (antibodies-online.com)
Human2
Roles of aquaporins in human cancer have been reviewed as have their folding pathways. (wikipedia.org)
AVP docking in the AVP V 2 receptors along the collecting ducts causes phosphorylation of aquaporin 2 (AQP2), insertion of the water channel into the apical membrane, and increased osmotic permeability, leading to water reabsorption. (medscape.com)
AQP2, AQP3, and AQP4 are located in the principal cells of the kidney collecting duct. (medscape.com)
However, AQP2 expression is the main target of vasopressin in regulating osmosis in the collecting duct. (medscape.com)
AQP58
1. Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas. (nih.gov)
5. Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5. (nih.gov)
18. Decreased expression of AQP1 and AQP5 in acute injured lungs in rats. (nih.gov)
Our study aimed to determine whether the altered expression of biomarkers linked to corneal injuries, such as the edema-regulating proteins aquaporin-1 and aquaporin-5 (AQP1 and AQP5), occurred following primary blast exposure. (molvis.org)
Corneas obtained from the euthanized blast-exposed and control rabbits were processed for quantitative PCR and western blot to quantify mRNA and the protein expression of AQP1 and AQP5. (molvis.org)
Western blot analyses of whole cornea lysates revealed that the expression levels of AQP1 and AQP5 were approximately 2- and 1.5-fold higher, respectively, in blast-exposed rabbits compared to controls. (molvis.org)
The AQP5-IS pattern changed from a mixed membrane and cytoplasmic expression in the controls to predominantly cytoplasmic expression in the basally located cornea epithelial cells of blast-exposed rabbits. (molvis.org)
Primary blast exposure resulted in edema-related changes in the cornea manifested by the altered expression of the edema-regulating proteins AQP1 and AQP5 with blast overpressure-specific impulses. (molvis.org)
Cyclic adenosine mon1
[ 9 ] In the collecting duct cell, AVP targets the AVP V 2 receptor, activating protein kinase by way of cyclic adenosine monophosphate (cAMP), and phosphorylates aquaporins that insert into the luminal cell membrane of the collecting duct. (medscape.com)
Proteins2
According to our findings, tested aquaporin proteins may play roles in T cell activation, differentiation, and apoptosis. (iyte.edu.tr)
[ 17 ] The movement of water across cell membranes in the kidneys is achieved by way of water channel proteins, or aquaporins. (medscape.com)
AQP81
13. Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium. (nih.gov)
MRNA1
Furthermore, qRT-PCR indicated that yellow tea extract regulated genes associated with the constipation state, raised 5-HT3 and 5-HT4 and reduced AQP3 and AQP4 mRNA expression. (pubmed.pro)
[ 8 ] Increased COX-2 leads to the production of prostaglandin E2 (PGE2), which interferes with the ability of the collecting duct to concentrate urine by modulating the expression of aquaporin-2 (Figures 1 and 2). (medscape.com)
Vasopressin1
[ 8 ] This interferes with the cell's responsiveness to aldosterone and vasopressin, which, in turn, limits insertion of aquaporin-2 and leads to decreased water reabsorption. (medscape.com)
Roles1
Roles of aquaporins in human cancer have been reviewed as have their folding pathways. (wikipedia.org)
[ 20 ] Activation of V 2 receptors also stimulates the expression of epithelial sodium channels, which are primarily located in the distal nephron. (medscape.com)
The goal of this study is to detect the expression level of AQP1, AQP3, and AQP4 in activated and apoptotic T cells. (iyte.edu.tr)
Cell2
Until now, it has been shown that AQP1, 3 and 5 expressed in both B and T lymphocytes of mice, regulate cell volume. (iyte.edu.tr)
Water flows through AQP-2 and finally through AQP-3 or AQP-4 to the basal surface of the cell. (medscape.com)
Reactions1
In termination to complex infancy, pathways of all 3 post-synaptic HAT reactions have required known to bring regions( Glozak et al. (evakoch.com)
Water channel2
14. Expression and immunolocalization of water-channel aquaporins in the rat and mouse mammary gland. (nih.gov)
15. Aquaporin 1water channel is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune pancreatitis. (nih.gov)
Urinary1
They thus are to urinary adenine via the BRAF-MEK phosphatidylinositol-3,4,5-trisphosphate regulation. (familie-vos.de)
Activation2
However, aquaporin expression involved in activation, proliferation, and differentiation as well as apoptosis of T cells are not well known yet. (iyte.edu.tr)
In the yielding signal several collagens associate successive on their salicylic neurons and AQP3 and AQP4 on their cyclin-dependent T-cells to return regulation across the activation. (familie-vos.de)
Include1
The third subfamily, with little conserved amino acid sequences around the NPA boxes, include 'superaquaporins' (S-aquaporins). (wikipedia.org)