• When GlaxoSmithKline was faced with the challenge of improving efficiency in modeling and simulation, the Research, Modeling and Simulation team at GSK’s clinical development organization turned to Univa technology to develop new, faster methods of establishing and running models for a drug’s effects on the body. (bitpipe.com)
  • The Research, Modeling and Simulation team first automated the process of model selection through an algorithmic approach. (bitpipe.com)
  • Using the selection algorithm to pick better models faster â€" and then running more models at a time using the grid â€" has allowed the Research, Modeling and Simulation team to achieve significant productivity gains. (bitpipe.com)
  • Modern neuroscience has established numerical simulation as a third pillar supporting the investigation of the dynamics and function of neuronal networks, next to experimental and theoretical approaches. (frontiersin.org)
  • In parallel with the experimental study, a simulation approach is carried out. (illinois.edu)
  • To date, CIERA 's erosion prediction capabilities have been demonstrated in simulations of pressurized fuel through aluminum channels and a heavy-duty fuel injector, and validated against available experimental data. (anl.gov)
  • We were also able to assess the geometry of the molecules in the monolayer using different experimental techniques and simulations. (rug.nl)
  • We demonstrate the viability of the approach by presenting experimental results from applications in coupled fusion plasma simulations that illustrate the performance impact of using containers to deploy the node-level workloads, in conjunction with the user mountable XFS file systems to ameliorate the load on the Lustre parallel file system. (ornl.gov)
  • Concurrently with the experimental work a numerical simulation was developed with which to interpret the laboratory data and to become a design tool of media processing and development. (europa.eu)
  • Owing to its theoretical transferability and ability to use solely experimental static structures as training data, we anticipate that this approach will prove advantageous for developing new protein force fields and further advancing the study of protein dynamics, folding, and interactions. (bvsalud.org)
  • Our simulations are targeted to specific experimental designs and allow both to understand the underlying physics and to optimize electro-optical devices. (lu.se)
  • Numerical simulations of particulate suspensions via a discretized Boltzmann equation. (crossref.org)
  • In parallel, MK Tech Solutions' simulation modeling was optimized based on the experiments, enabling numerical simulations to be used to design the 3-D large-scale experiments. (serdp-estcp.org)
  • In addition, during an initial round of 3-D heat-transfer experiments in large containers (up to 150 m³), the progression of heating to 100°C and accompanying desaturation were monitored using 300 temperature sensors and 35 time-domain reflectometry probes, respectively, allowing comparisons of the physical experiments and accompanying numerical simulations. (serdp-estcp.org)
  • The SAIL project developed a Decision Support System (DSS) and a Discrete Event Simulation (DES) to support the management of port intermodal facilities in a European context. (europa.eu)
  • This paper presents a fast surface voxelization technique for the mapping of tessellated triangular surface meshes to uniform and structured grids that provide a basis for CFD simulations with the lattice Boltzmann method (LBM). (cambridge.org)
  • Parallel computation is becoming a critical part of circuit simulators designed to handle large-scale VLSI circuits. (techdesignforums.com)
  • Rarefied Gas Dynamics: Theory and Simulations, Vol. 159 of Prog. (crossref.org)
  • Argonne has developed an approach for modeling cavitation-induced erosion for use with any multiphase computational fluid dynamics ( CFD ) code (e.g. (anl.gov)
  • Once the simulation finishes, it shows the animation of the dynamics. (mathworks.com)
  • The second model therefore adopted the molecular dynamics approach while taking over much of the framework of the Monte-Carlo calculation. (europa.eu)
  • Once trained, the model can be employed to run parallel molecular dynamics simulations and sample folding events for proteins both within and beyond the training distribution, showcasing its extrapolation capabilities. (bvsalud.org)
  • By conducting molecular dynamics (MD) simulations on various protein-ligand complexes and metadynamics (MTD) simulations on a ligand, we showcase the capabilities of our implementation of NNP/MM. It has enabled us to increase the simulation speed by â ¼5 times and achieve a combined sampling of 1 µs for each complex, marking the longest simulations ever reported for this class of simulations. (bvsalud.org)
  • For training, we build a unique dataset of unbiased all-atom molecular dynamics simulations of approximately 9 ms for twelve different proteins with multiple secondary structure arrangements. (bvsalud.org)
  • These results indicate that machine learning coarse-grained potentials could provide a feasible approach to simulate and understand protein dynamics. (bvsalud.org)
  • No. These two models share certain features and were developed in parallel originally, but exhibit a number of fundamental differences, particularly regarding the representation of vegetation dynamics and (from LPJ-GUESS release version 3.0) nitrogen cycling. (lu.se)
  • The performance of the presented grid generation procedure is superior to the performance of the GPU-accelerated flow field computations per time step which allows efficient fluid-structure interaction simulations, without noticeable performance loss due to the dynamic grid update. (cambridge.org)
  • With tool interoperability, vendor lock-ins and tool life-cycle support as major challenges, this research project has focused on interoperability between the Modelica/Unified Modeling Language (UML)/Functional Mock-up Interface (FMI) standards, on improved support for state-machine modeling and debugging and on efficient simulation of large scale systems. (vinnova.se)
  • This project has resulted in improved support for synchronous language constructs and efficient parallel simulation in OpenModelica. (vinnova.se)
  • The ONETEP Linear-Scaling DFT code [1] combines the benefits of linear-scaling, efficient parallelisation, and variational convergence akin to plane-wave approaches, with a wide-ranging set of features. (aps.org)
  • While published analyses must be virtually independent of such modelling assumptions, the accuracy of the physics description provided by the simulation codes is crucial for efficient exploitation of LHC data. (lu.se)
  • Usually, a speedup between two and three orders of magnitude in comparison to HR simulations can be obtained. (osti.gov)
  • It can simulate large industrial designs in parallel achieving speedups of orders of magnitude over SPICE without jeopardizing accuracy. (techdesignforums.com)
  • For the distribution of the optimization tasks, which will be introduced in Chapter 2, several approaches have been developed, but so far there is no stan- dard that ts every problem. (grin.com)
  • In this thesis, the prob- lem of discrete multistage optimization processes and possible distributed solution approaches will be discussed. (grin.com)
  • We describe a series of optimization steps that cooperate to minimize simulation depth while scaling to problem sizes on the order of a billion gates. (aaai.org)
  • The procedure involves four main tools: the multi-objective particle swarm optimization method (MOPSO) to find Pareto solutions in one run, the K-means clustering algorithm to reduce the size of the obtained non-dominated solutions, the pseudo-weight vector approach (PWV) to facilitate the decision making and to select some adequate solutions, and finally, CFD simulations to analyze the retained optimal solutions. (iwaponline.com)
  • Monte carlo simulations of parallel charged platelets as an approach to tactoid formation in clay. (lu.se)
  • Simulations and experiments confirm the benefits of the unified approach with greater accuracy and wider applications. (hindawi.com)
  • It became clear from both the simulations and the parallel experiments that complex time effects play an important role in the behaviour of the dispersions and true equilibrium situations may be difficult to find and may in fact not occur in real systems. (europa.eu)
  • That is, while plenty of individual LHC physics analyses have considered private plots of a generator's predictions, there has not been a study broad enough to provide side-by-side displays of how different simulation codes perform, both with respect to each other and to data from previous experiments. (lu.se)
  • These processes focus on nonlinearity, and a test function is used to compare the di erent approaches. (grin.com)
  • Six ToK workshops were organized, in the last period the 4th TOK was held in February 2012, the 5th TOK and the 6th TOK were organized in conjunction since all the activities in Wp5 and WP6 have been carried out in a coordinated way in a track session during the European Modelling & Simulation Symposium 2013 (EMSS 2013), "Simulation Approaches in Logistics Systems", September, 2013. (europa.eu)
  • [6] MPI is now a widely available communications model that enables parallel programs to be written in languages such as C , Fortran, Python , etc. [8] The MPI specification has been implemented in systems such as MPICH and Open MPI . (wikipedia.org)
  • State-of-the-art software tools for neuronal network simulations scale to the largest computing systems available today and enable investigations of large-scale networks of up to 10 % of the human cortex at a resolution of individual neurons and synapses. (frontiersin.org)
  • Our results show that the new data structures and communication scheme prepare the simulation kernel for post-petascale high-performance computing facilities without sacrificing performance in smaller systems. (frontiersin.org)
  • To achieve these goals, we developed measurement methods for radar targets, surrogate targets with realistic radar response, and a radar simulation tool for virtual testing of radar systems. (vinnova.se)
  • In parallel, a radar simulation tool to be used for virtual testing of radar systems was further developed with realistic radar models. (vinnova.se)
  • In the field of time response analysis of multi-core systems, simulation-based approaches and mathematical formal methods exist. (offis.de)
  • This thesis deals with the mathematical analysis of these type of systems as well as their simulation. (tu-darmstadt.de)
  • First the co-simulation waveform relaxation method is analysed for field-circuit coupled systems arising from magnetoquasistatic fields with eddy current effects on superconducting coils. (tu-darmstadt.de)
  • The algorithm is investigated in the context of differential algebraic equations by studying its applicability to nonlinear higher index systems arising e.g. from circuit simulation. (tu-darmstadt.de)
  • Application of CIERA to simulations of multiphase flow systems can guide design studies in improving system durability and reducing maintenance costs. (anl.gov)
  • Coarse-grained simulations identify relevant structural states in the ensemble with comparable energetics to the all-atom systems. (bvsalud.org)
  • Echoes are parallel, monochromatic X-ray beams which appear, with time delay, from the diffraction of perfect crystals, which are often used in ultrafast optics systems. (lu.se)
  • Our work aims to increase the scalability of the analysis methods by using probability-based simulation techniques. (offis.de)
  • The linear subdomain is further partitioned by ParMETIS [9] and in parallel solved by the iterative solver GMRES with BoomerAMG as the preconditioner to achieve parallel scalability. (techdesignforums.com)
  • An improved parallel simulation flow with new parallel device model evaluation, numerical integration and linearization steps that increase parallel scalability of the proposed approach. (techdesignforums.com)
  • In this work, a parallel computational approach is presented that relies on using scalable open source libraries and utilizes a kernel-independent Fast Multipole Method (FMM) to evaluate the integrals in O ( N ) operations, with O ( N ) memory cost, thereby substantially improving the scalability and efficiency of computational integral methods. (osti.gov)
  • We demonstrate the accuracy, efficiency, and scalability of our approach in the context of two examples. (osti.gov)
  • To achieve the best possible traction, optimisation calculations with particle simulations replicating the sand on Phobos were used. (dlr.de)
  • With the molecular dynamic simulation good agreement has been achieved between the measured and calculated macroscopic magnetic properties of advanced metal particle dispersions. (europa.eu)
  • This approach is not feasible for large scale urban catchments with a large number of buildings. (osti.gov)
  • Approaches based on the density matrix can exploit real-space localisation to achieve linear-scaling with system size and make such calculations feasible and highly parallel. (aps.org)
  • This unique definition necessitates a topology based neighbor search as a preprocessing step, but also enables parallel implementation. (cambridge.org)
  • A new and improved parallel implementation that runs on up to 64 processors. (techdesignforums.com)
  • To tackle this issue, we introduce an optimized implementation of the hybrid method (NNP/MM), which combines a neural network potential (NNP) and molecular mechanics (MM). This approach models a portion of the system, such as a small molecule, using NNP while employing MM for the remaining system to boost efficiency. (bvsalud.org)
  • Participants also agreed on the importance of local action and the engagement of communities through a whole-of society approach, preparedness for emerging public health threats, and evaluation and monitoring of the implementation of the 2030 Agenda. (who.int)
  • The porous shallow water model is an alternative approach that aims to reduce computational cost by using a coarse resolution and accounting for unresolved processes by means of the porosity terms. (osti.gov)
  • Learning Goals: Students will be able to: Discuss basic electricity relationships in series and parallel circuits & Analyze the differences between real circuits and the simulated ones & Build circuits from schematic drawings & Use a multimeter to take readings in circuits & Provide reasoning to explain the measurements in circuits. (colorado.edu)
  • The paper presents a fully parallel transistor-level full-chip circuit simulation tool with SPICE accuracy for general circuit designs. (techdesignforums.com)
  • With the rapid scaling down of VLSI feature sizes, the huge size of today's designs is making transistor-level circuit simulation extremely time-consuming. (techdesignforums.com)
  • The shift from single-core to multicore processing is creating new challenges and opportunities for circuit simulation. (techdesignforums.com)
  • Several parallel circuit simulation techniques have been proposed. (techdesignforums.com)
  • The waveform relaxation technique has been proposed for parallel circuit simulation [8], however, it is not widely used because it is only applicable to circuits with unidirectional signal flow. (techdesignforums.com)
  • The method proposed here is a fully parallel circuit simulation for full-chip transient circuit analysis. (techdesignforums.com)
  • It can perform transistor-level full-chip circuit simulation for general circuit designs with interconnect, clock, power and ground, and analog components with capacitive and inductive couplings. (techdesignforums.com)
  • Within this framework, experienced researchers worked on a precise representation, modelling and simulation of the intermodal port and of its connection with a dry-port area. (europa.eu)
  • Typically in electrical engineering a network modelling approach for the simulation of devices and their surrounding circuitry is taken, where each device is considered by a voltage-to-current relation. (tu-darmstadt.de)
  • This interdisciplinary conference on modelling and simulation of real-world phenomena will draw academic and industry leaders from all relevant fields. (wikicfp.com)
  • ICCS intends to provide a forum to disseminate world-leading research in the field of (scientific) Computational Science and in particular to highlight the role which modelling and simulation plays in future scientific discovery. (wikicfp.com)
  • The researchers use Modelica as the modelling language and Dymola as the environment for developing and running the simulations. (dlr.de)
  • We consider an application of scheduling to hardware-accelerated functional verification, a massively-parallel computational paradigm used in the simulation of complex integrated circuits. (aaai.org)
  • In this talk, we present our work on coupling the bulk synchronous parallel paradigm for simulation with a distributed task-based one for analysis. (anl.gov)
  • For the control of buck converters, the pulse width modulation (PWM) is a conventional approach but suffers from the bottleneck of model precision, especially when facing the possible disturbances [ 1 , 9 , 13 , 16 ]. (hindawi.com)
  • However, due to the diversity and complexity of model uncertainties and external disturbances of converters, whether there is a unified approach for the design and analysis of SM controllers is an interesting problem worthy of consideration but has been barely investigated. (hindawi.com)
  • By combining the lubricant effect in the inlet header taken into account by the newly proposed method and the parallel microchannel tubes model, a complete evaporator model is developed in which lubricant effect is fully considered. (illinois.edu)
  • To achieve maximum parallelism, device model evaluation is also done in parallel. (techdesignforums.com)
  • It provides orthogonal improvements over methods like WavePipe [3] and MAPS [4] and complements other parallel matrix solver and/or parallel device model evaluation-based approaches in a number of ways. (techdesignforums.com)
  • We propose a bridging model between the two paradigms and validate it through a prototype called DEISA, which supports coupling MPI parallel codes with analyses written using Dask. (anl.gov)
  • The bridging model requires minimal modifications of both the simulation and analysis codes compared to their post hoc counterpart. (anl.gov)
  • The simulation model as a whole contains the mechanical model of the rover, complete with wheels, actuators, mechanisms and sensors, the model of the environment (ground geometry and properties) and the contact mechanics as a connection between the two, as well as a control unit for the actuators. (dlr.de)
  • The simulation model must therefore be able to create soil geometry and rocks according to the best statistical parameters determined by planetary scientists. (dlr.de)
  • The simulation of a given basic process and Programming Languages (e.g. shape recognition) is based on a neurophy- siological model, which is used to formulate a Psychobiology is a branch of psychology mathematical model in the format: input signal concerned with basic psychological pr ocesses representation processing algorithm out- such as attention, perception, memory, learning, put signal. (bvsalud.org)
  • In the mixed effects model, random intercepts of the country and parallel of latitude were applied as 3 levels of the model (prevalence rate of each study, nested within countries and latitude parallel). (who.int)
  • The core algorithm is optimized for massively parallel execution on graphics processing units (GPUs) and is based on a unique dissection of the inner body shell. (cambridge.org)
  • In parallel, process-based mathematical models have been developed to study the transmission of AMROs ( 9 - 11 ), simulate the competition between resistant and sensitive strains ( 12 - 16 ), and evaluate the effects of various policies ( 17 - 22 ). (cdc.gov)
  • As opposed to conventional approaches that minimize the errors in the predicted source terms, ChemNODE uses neural ordinary differential equations (NODEs), combining the power of machine learning and numerical methods, to directly minimize the loss based on the chemical species' profiles. (anl.gov)
  • Juliette Stecenko is using modern supercomputers and quantum computing platforms to perform astronomy simulations that may help us better understand where we came from. (bnl.gov)
  • As an intern through DOE's Science Undergraduate Laboratory Internship s (SULI) program, administered at Brookhaven by the Office of Educational Programs (OEP), Stecenko is using modern supercomputers and quantum computing platforms to perform astronomy simulations that may help us better understand where we came from. (bnl.gov)
  • However, the computational cost of this type of schemes is high, such that HR two-dimensional shallow water simulations with practical relevance have to be run on supercomputers. (osti.gov)
  • Finally, two approaches are proposed for the combination of Parareal and waveform relaxation. (tu-darmstadt.de)
  • Simulation studies have established these two methods as the most accurate. (wikibooks.org)
  • Our goal in this project is to demonstrate potential improvements in the analyzability of architectures with respect to size (more cores) and complexity (heterogeneity and memory hierarchies) by using probability-based methods instead of existing analytical or state-based formal approaches. (offis.de)
  • Parallel domain decomposition methods have been developed for the simulation of linear circuits such as power ground networks [2]. (techdesignforums.com)
  • Particularly with the rise of multivariate methods, such as have been discussed in other ACAT parallel sessions, the discrimination between signal and back- ground is often tuned to predictions from Monte Carlo event generators. (lu.se)
  • Juliette Stecenko, shown at the Green Bank Observatory during her time as a student at Rutgers University, worked with Michael McGuigan of Brookhaven Lab's Computational Science Initiative to develop a quantum computing approach for tackling cosmological questions by breaking them into smaller problems. (bnl.gov)
  • This paper proposes a novel discrete-time sliding mode (DTSM) control approach to address the robust stability problem of buck converters with multiple disturbances. (hindawi.com)
  • To further speed up simulation time, the parallel-in-time method Parareal is analysed. (tu-darmstadt.de)
  • Parallel storage solutions from Panasas enable organizations undertaking complex computer modeling, simulation and other storage-intensive tasks to more rapidly accelerate their time to results. (networkcomputing.com)
  • This paper presents a approach for measuring the time spent by HPC applications in the operating system's kernel. (researchgate.net)
  • As the number of nodes in a cluster increases, the rapid growth in the complexity of the communication subsystem makes message passing delays over the interconnect a serious performance issue in the execution of parallel programs . (wikipedia.org)
  • One approach to reducing communication overhead is the use of local neighborhoods (also called locales ) for specific tasks. (wikipedia.org)
  • Scipy 2022: Can we analyse the largest ocean simulation ever? (speakerdeck.com)
  • Diese Arbeit befasst sich mit der mathematischen Analyse dieser Systeme, sowie deren Simulation. (tu-darmstadt.de)
  • Computer simulation of the MMX rover in the driving position of the locomotion system. (dlr.de)
  • Computer simulation has helped science malaria, has now become a socioeconomic in general, and medicine in particular, burden for many countries [ 2,3 ]. (who.int)
  • With the exception of the extremely a computer simulation, we investigated rare mutations, only those individuals the effect on the population disease born to 2 gene carriers (heterozygotes or gene frequency and the frequencies of homozygotes) may develop thalassaemia heterozygous and homozygous individuals major. (who.int)
  • Weighted graphs and graph decomposition heuristics are used in the Xyce parallel circuit simulator [7] to partition the circuit graph to achieve load balance and minimize communication costs. (techdesignforums.com)
  • Containers for Massive Ensemble of I/O Bound Hierarchical Coupled Simulations. (ornl.gov)
  • We also present results from production runs showing the ability of the ensemble simulations to scale to hundreds of Cori Haswell nodes, with little or no overhead. (ornl.gov)
  • The Siemens circuit simulator TITAN [6] partitions the circuit by minimizing the total wire length for the circuit, and parallel simulation is performed by using a non-overlapping domain decomposition technique. (techdesignforums.com)
  • We then present selected preliminary results from studies of event shapes and hadronisation observables from e+e- colliders, and of minimum bias and underlying event observables from the Tevatron, and comment on the approach needed with early LHC data to best exploit the potential for new physics discoveries at the LHC in the next few years. (lu.se)
  • Historically, the two typical approaches to communication between cluster nodes have been PVM, the Parallel Virtual Machine and MPI, the Message Passing Interface . (wikipedia.org)
  • The team leveraged GSK’s installed grid infrastructure to assess hundreds of models in parallel. (bitpipe.com)
  • The proposed overlapping domain decomposition approach partitions the circuit into a linear subdomain and multiple nonlinear subdomains based on circuit nonlinearity and connectivity. (techdesignforums.com)
  • By applying Markov state models, native-like conformations of the simulated proteins can be predicted from the coarse-grained simulations. (bvsalud.org)
  • Here, we approach this problem by constructing coarse-grained molecular potentials based on artificial neural networks and grounded in statistical mechanics. (bvsalud.org)
  • In the laboratory component, simulations were conducted to evaluate the biomechanical stresses associated with drywall handling techniques identified from the field investigation. (cdc.gov)
  • Our approach targets an industrial acceleration architecture containing 262,144 parallel processors. (aaai.org)
  • The analysis of the timing behavior of software running in parallel on complex multi-core platforms is difficult. (offis.de)
  • Argonne has developed an approach for spark-ignition modeling of complex engine conditions, for use within industry CFD solver packages, such as Convergent Science's CONVERGE framework. (anl.gov)
  • They are, however, often complex to set up and can require to re-develop parallel versions of the analysis from scratch. (anl.gov)
  • As a result of this growth, Panasas has added a third research and development (R&D) facility based in Minneapolis, Minn. to further drive technology advances in Panasas Parallel Storage Clusters, which are powered by the Panasas ActiveScale(R) Operating Environment. (networkcomputing.com)
  • Our proven parallel clustered storage technology continues to gain widespread global acceptance with users of very demanding applications," said Victor Perez, president and CEO at Panasas. (networkcomputing.com)
  • A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. (mdpi.com)
  • The aim of this work is to present a high order, parallel, multirate method for two heterogeneous coupled heat equations which could be applied to FSI problems. (lu.se)
  • Instead, DLR has developed detailed simulation models of the rover. (dlr.de)
  • This approach is borrowed from so-called gap models . (lu.se)
  • Pauline's research focuses on building such models through a physics-informed learning based approach, taking advantage of the available measurements. (lu.se)
  • However, the efficiency of the approach can deteriorate quickly as the size of interface increases. (techdesignforums.com)
  • Areas to be blocked in the parallel, opposed AP-posteroanterior and lateral beams are indicated in the corners of these simulation images. (medscape.com)
  • We describe the design of a hierarchical simulation structure using the Integrated Plasma Simulator (IPS) that enables the flexible execution of coupled simulations at the system, node, and core level using the same coupling abstraction and API. (ornl.gov)
  • However, predicting such memory traffic is difficult because of the interplay of prefetchers, compilers, parallel execution, and innovations in manufacturer-specific micro-architectures. (researchgate.net)
  • The second approach involves adding an amp simulation in parallel for more growl. (izotope.com)
  • 5.4 Schematic representation of the parallel Scatter Search approach (comp. (grin.com)