Applications of stable isotopes. Medical search. Frequent questions

Stable isotopes of carbon (δ13C), sulfur (δ34S), oxygen (δ18O), hydrogen (δ2H), nitrogen (δ15N), and radioactive isotope of hydrogen (tritium) have been applied in combination with conventional techniques (chemical) to investigate Karachi coastal water pollution due to Layari and Malir rivers, which mainly carry the domestic and industrial wastewater of Karachi Metropolitan. (intechopen.com)
Tin 119 Metal (Tin-119) is a stable (non-radioactive) isotope of Tin. (americanelements.com)
Rhodium from this source contains radioactive isotopes with half-lives of up to 2.9 years. (newworldencyclopedia.org)
Artificial radioactive isotopes of selenium have also been created by neutron activation. (cdc.gov)
Stable and radioactive isotopes play an important role in basic research and applied programs, and are vital to the mission of many Federal agencies. (anl.gov)
Natural strontium is not radioactive and exists in four stable types (or isotopes), each of which can be written as 84 Sr, 86 Sr, 87 Sr, and 88 Sr, and read as strontium eighty-four, strontium eighty-six, etc. (cdc.gov)
Strontium can also exist as radioactive isotopes. (cdc.gov)
90 Sr, or strontium ninety, is the most hazardous of the radioactive isotopes of the chemical element strontium. (cdc.gov)
Each radioactive element, including strontium, constantly gives off radiation, and this process changes it into an isotope of another element or a different isotope of the same element. (cdc.gov)

This study is the first of its kind to analyse carbon, nitrogen and sulphur stable isotope data from skeletons of the eleventh-seventeenth centuries in Portugal. (springer.com)
This fractionation enables the use of stable nitrogen isotopes (δ 15 N) to infer trophic level, and high δ 15 N recorded in bone collagen usually indicates high-protein diets (Sponheimer et al. (springer.com)
The key to the authors' approach lies in carbon and nitrogen stable isotopes, chemicals that exist in animal tissues, which vary depending on diet. (eurekalert.org)

Richards and Hedges 1999 ), especially when combined with carbon isotope data. (springer.com)
Carbon isotopes. (chipsbooks.com)

Hydrogen isotopes. (chipsbooks.com)
This session aims to bring together scientists from different fields applying single and dual oxygen and hydrogen isotope approaches on environmental-derived compounds for the reconstruction of climatic and biological processes that go beyond standard isotope analyses of water. (copernicus.org)
We also encourage people working with all techniques (IRMS-, NMR- or spectroscopy-based) to present advances in methods, as well as researchers focusing on improving oxygen and hydrogen isotope-based models to discuss their approaches. (copernicus.org)
In summary, the session will offer an overview on oxygen and hydrogen applications across different ecosystems in order to facilitate the interpretation of compound-specific isotope patterns. (copernicus.org)

Analysis of stable isotope ratios from mineralised tissue has been widely used for dietary reconstruction. (springer.com)
Archaeologists at UC Santa Cruz used predictive modeling to map strontium isotope ratios across all of modern-day Angola, a region in Southwest Africa that was once a major hub for the transatlantic slave trade. (ucsc.edu)
Researchers compared the resulting map with existing data on strontium isotope ratios from human remains to predict likely regions of origin within Angola for four individuals who had been buried in cemeteries for enslaved people across the Americas. (ucsc.edu)
Plants at the base of the food chain take up strontium isotopes from the soil in ratios that can differ slightly from that of the bedrock or soil, and local animals then incorporate the strontium isotope ratios from plants into their developing bones and teeth via their diet. (ucsc.edu)
Archaeologists can perform a stable isotope analysis on human remains to determine strontium ratios. (ucsc.edu)
Xueye Wang, lead author of the new paper, explained that Angola has ancient bedrock exposed at the surface on high plateaus near the center of the country, which gives the area very unique strontium isotope ratios. (ucsc.edu)
However, lack of samples from the broader region for use in stable isotope analysis has previously prevented archaeologists from pinpointing origins of human remains within Western Africa through strontium isotope ratios. (ucsc.edu)

SISCAPA is an extension of the well-known gold-standard methods of stable-isotope dilution for quantitation of small molecules by mass spectrometry (MS). Rather than measure an intact protein directly by mass spectrometry, SISCAPA makes use of proteolytic digestion (e.g., with the enzyme trypsin) to cleave sample proteins into smaller peptides ideally suited to quantitation by mass spectrometry. (wikipedia.org)
The SISCAPA workflow adds a specific enrichment step to the isotope dilution method in which a selected target peptide, together with its associated SIS internal standard, is captured by a sequence-specific anti-peptide antibody. (wikipedia.org)
Quantification of midostaurin in plasma and serum by stable isotope dilution liquid chromatography-tandem mass spectrometry: Application to a cohort of patients with acute myeloid leukemia. (bvsalud.org)
A stable isotope dilution liquid chromatography - tandem mass spectrometry method was developed and validated for the determination and quantification of midostaurin in human plasma and serum . (bvsalud.org)
For assessing the folate content in a range of Brazilian PANCs, we extended the validation of an existing stable isotope dilution assay (SIDA) for the stably 13 C-labelled 10-formyl-Pte[ 13 C 5 ]Glu (10-CHO-Pte[ 13 C 5 ]Glu). (frontiersin.org)

To develop the model, co-authors Drs. Matt Chatfield and Cheryl Frederick collected claw tips from 35 wild wood turtles in Maine and compared their isotopes with those of 36 captive turtles throughout the eastern U.S. Because captive and wild turtles have drastically different diets, the isotopic signatures of their tissues were also expected to differ. (eurekalert.org)
We have been examining these problems by modeling the effects of loading the atmosphere with H2, characterizing the stable isotopic (D/H) variability of atmospheric H2, and determining the isotopic characteristics of H2 of different origins. (caltech.edu)
In contrast, the two estimators of trophic width (the omnivore index and the total isotopic area) were not strongly related, since the relationship between modelling and stable isotope results was evident only for some species. (ufz.de)
The recent development of the clumped isotope paleothermometer has expanded the range of possible applications of these isotopic techniques to cover more environments and time periods. (colorado.edu)
Finally, I will present an investigation of intriguing isotopic results from one site that reveal information about the life cycle of an extinct bivalve species and demonstrate the breadth of possible applications of these isotopic techniques. (colorado.edu)

In most cases, hydrograph separations are conducted using the stable isotopes of water, since they are ideal, conservative tracers. (carleton.edu)

Oxygen isotopes. (chipsbooks.com)
This differs in important waysfrom Urey's classic carbonate-water oxygen isotope thermometer (or similar ones based on other set ofs phases. (caltech.edu)
Therefore, it rigorously constrains temperature without needing to know the oxygen isotope composition of water, or anything else besides carbonate). (caltech.edu)
Selenium reacts with oxygen to form a number of oxides, the most stable of which is selenium dioxide. (cdc.gov)

Cobalt-60 is produced by exposing Cobalt-59, a stable isotope, with neutrons. (edf.fr)

Application of LICA Soil Greenhouse Gas Flux Monitoring System1 AbstractThe process of soil Greenhouse gas emissions or absorptions is extremely complex in terrestrial ecosystems. (li-ca.com)

Recent advances in metabolomics have extended the capability of isotope-assisted studies to reveal global metabolism. (mdpi.com)
For instance, isotope-assisted metabolomics technology has enabled the mapping of a global metabolic network, estimation of flux at branch points of metabolic pathways, and assignment of elemental formulas to unknown metabolites. (mdpi.com)
The combination of high-resolution LC-MS-based untargeted metabolomics with stable isotope tracing provides a global overview of the cellular fate of precursor metabolites. (acs.org)

Oelze explained that while genetic analysis of human remains can trace a person's ancestry back to a particular region, sophisticated forms of stable isotope analysis powered by machine learning can go further. (ucsc.edu)
Picarro is a leading provider of solutions to measure greenhouse gas (GHG) concentrations, trace gases and stable isotopes across many scientific applications and industrial markets. (esri.com)

Associate Professor of Anthropology Vicky Oelze sorts ashed plant samples in preparation for strontium separation in the clean labs at UCSC's W. M. Keck Isotope Laboratory. (ucsc.edu)
The research team used a similar process to get strontium isotope ratio data for Angola from herbarium specimens. (ucsc.edu)
Strontium is an element present in soil that comes in several different chemical forms, called isotopes. (ucsc.edu)
The team then used machine learning to combine the strontium isotope data from those samples with information about elevation, soil characteristics, climate, and geological variables across Angola. (ucsc.edu)
As a demonstration of the potential applications for their new map, researchers reviewed prior strontium isotope analysis of human remains in the Americas. (ucsc.edu)

Site-specific natural isotope fractionation by NMR. (chipsbooks.com)
The mass differences between isotopes leads to quantifiable kinetic- or mass dependent fractionation that is characteristic of the biological, chemical or physical history of a sample. (lu.se)

The aim of this study was to examine the trophic dynamics of representative species of the South Catalan marine ecosystem (North-western Mediterranean) using the Ecopath ecosystem modelling tool and the stable isotope approach. (ufz.de)

Tin has nine stable isotopes and 18 unstable isotopes. (americanelements.com)
A radionuclide is an unstable isotope that becomes more stable by releasing energy. (msdmanuals.com)

In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions. (nih.gov)

The results demonstrate that LC-MS/MS is a sensitive method for determining these compounds from two different matrices at the low concentrations that can result from spray drift and long range transport in non-target areas following agricultural applications. (cdc.gov)

Isotope data: An ISCO auto-sampler was deployed in the study area on 21 March 2014 and programmed to collect 1 L samples at 1 or 2 hour intervals after triggering by an increase in water level (i.e., signaling a storm event producing a rising hydrograph). (carleton.edu)
Diet, Status, and Social Inequality among Fisher-Foragers: Stable Isotope Data from Three Sites in southern California. (lu.se)

Stable isotopes of carbonate have long been used to reconstruct past climate and environmental conditions. (colorado.edu)

This technique will provide conservation law enforcement officials a much-needed wildlife forensic tool and is the first crucial step in developing a more widespread application used to help combat the illegal turtle trade," said Hopkins. (eurekalert.org)

Gas-Isotope-ratio mass spectrometry (G-IRMS) allows the precise measurement of mixtures of naturally occurring light stables isotopes. (lu.se)

Published in the journal Biology 's special issue, Applications of Stable Isotope Analysis in Ecology, Dr. Jack Hopkins, President and Associate Professor of the Center for Wildlife Studies and colleagues describe a novel technique to prevent laundering one of Maine's imperiled species, the wood turtle. (eurekalert.org)

Isotope-labeling is a useful technique for understanding cellular metabolism. (mdpi.com)

This methodology enables detection of putative metabolites from biological samples and simultaneous quantification of the pattern and extent of isotope labeling. (acs.org)

Laboratory aspects of R.I. determination, model analysis, reflectivity, micro-hardness, cathodoluminescence, chemical and X-ray analysis and their application in natural mineral systems and assemblages. (uregina.ca)

Additionally, the human samples have higher stable isotope differences, in comparison with faunal samples, than would be expected within the food web, particularly for δ 13 C. This human bone collagen δ 13 C enrichment may reflect a diet rich in aquatic protein intake, which is also supported by δ 34 S archived in human and faunal samples, and the presence of oysters and cockles shells at the excavation. (springer.com)

In our contribution, we discuss the potential, the advances and the limitation of the coupled isotope approach based on leaf wax-derived n -alkane and hemicellulose-derived sugar biomarkers (δ 2 H n -alkanes - δ 18 O sugars ). (copernicus.org)
I will study the movement and foraging differentiation between sexes and ages of the swallows through application of light loggers and DNA barcoding approach from faeces samples. (lu.se)

Stable isotope standards and capture by anti-peptide antibodies (SISCAPA) is a mass spectrometry method for measuring the amount of a protein in a biological sample. (wikipedia.org)
Since the target peptide and SIS are chemically indistinguishable throughout the workflow, but can be measured separately by a mass spectrometer due to the mass difference of the stable isotope label, their ratio provides the desired quantitative estimate of the target peptide amount. (wikipedia.org)

LICA attended the Senior Seminar on Stable Isotope Application and Analysis Technology. (li-ca.com)
The botanists gave researchers permission to perform stable isotope analysis on 101 herbarium plant samples. (ucsc.edu)
Some applications of electrophoretic analysis. (chipsbooks.com)

A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. (mdpi.com)
In vivo research with stable isotopes in biochemistry, nutrition and clinical medicine: an overview. (nih.gov)
The synthesis of novel elements remained an interesting topic of research, but the new materials decayed so rapidly no practical applications were possible. (orionsarm.com)
Hundreds of applications in medicine, industry, national security, defense and research depend on isotopes as essential components. (anl.gov)
The Subcommittee is asked (see Charge) to establish the priority of research isotope production and development, and to form of a strategic plan for the NIPA Program. (anl.gov)
The report "Compelling Research Opportunities using Isotopes" and the NSAC letter of transmittal are available at the NSAC web page http://www.sc.doe.gov/np/nsac/nsac.html . (anl.gov)

Using stable isotopes from turtle claw tips, the authors produced a statistical model that can determine-with impressive accuracy-whether wood turtles are wild-caught or captive-bred. (eurekalert.org)

Some specialist spacecraft , vecs and even cyborgs may use less stable isotopes as power sources for radioisotope thermal generators, fission rockets and very small fission reactors. (orionsarm.com)
Military use of stable transuranics is much rarer since the Golden Age, given the relative ease with which compact laser-triggered fusion devices and antimatter-catalysed fission and fusion explosives can be made or obtained. (orionsarm.com)

Stable isotope ratio variation in natural systems reflects the dynamics of Earth systems processes and imparts isotope labels to Earth materials. (springer.com)

Finally, we used a mathematical model to simulate the population dynamics of 5 mosquito vector species and evaluate the effectiveness of the simulated adulticide applications. (cdc.gov)

The applications of stable isotopes to natural systems are thus extraordinarily broad, with new ideas being developed constantly. (lu.se)

Tin 119 Metal is one of over 250 stable metallic isotopes produced by American Elements for biological and biomedical labeling, as target materials and other applications. (americanelements.com)
Stable transuranic elements have not been found in nature, and must be synthesised. (orionsarm.com)

Ongoing applications include the thermal histories of aqueously altered meteorites, marine paleoclimate studies in 'deep' geologic history (the mesozoic, paleozoic and late pre-cambrian), and the body temperatures of the dinosours (roar! (caltech.edu)

Sequence stratigraphy of shoreface deposits (Embry vs Exxon models) and non-marine deposits (Shanley and McCabe vs Exxon models) and application in the Mannville Group in Saskatchewan. (uregina.ca)

Principles and application of fluid inclusion studies. (uregina.ca)

First Singularity and modosophont industrial bases continue to make use of transuranics to this day, often for radiation shielding but also with highly stable forms (with half-lives generally measured in centuries or millenia) used for compact counterweights, gyroscopes and flywheels in devices of all sizes from synsects to interstellar vehicles. (orionsarm.com)

Under normal environmental conditions, only the +2 oxidation state is stable enough to be important. (cdc.gov)

Our first application focused on determining the growth temperatures of soil carbonates from the Altiplano, which can be compared to the 'surface lapse rate' to constrain its uplift history. (caltech.edu)

Hydrograph separation using stable isotopes: review and evaluation. (carleton.edu)

The basic ideas of soft x-ray microscopes, and their application to organic material detection from sample masses as small as 10 −17 g, are briefly outlined. (nationalacademies.org)

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