• This article provides information on 4,4′-DMAR, a new psychoactive substance that is a derivative of aminorex, an amphetamine-like appetite suppressant. (safrole.com)
  • The results were then compared with those of d-amphetamine, aminorex, and (±)-cis-4-MAR. All substances were found to exhibit potent releasing activity at DAT, with considerable potency at NET. (safrole.com)
  • It is a derivative of aminorex and 4-methylaminorex (4-MAR), two synthetic stimulants that are strictly controlled under the 1971 United Nations Convention on Psychotropic Substances, with 4-MAR listed in Schedule I and aminorex listed in Schedule IV. (safrole.com)
  • Aminorex , a stimulant and appetite suppressant, was withdrawn by the FDA in 1972 after it caused a number of pulmonary hypertension cases that resulted in heart failure and death. (cobalis.com)
  • Chlorphentermine (Apsedon, Desopimon, Lucofen) is a stimulant drug which was used as an appetite suppressant . (wikidoc.org)
  • Chlorphentermine itself is a relatively weak stimulant with little abuse potential, but is classed as a Schedule 3 drug in the USA due mainly to its similarity to other appetite suppressants such as diethylpropion which have been more widely abused. (wikidoc.org)
  • This is the same mechanism of action as other stimulant appetite suppresants such as sibutramine, diethylpropion, and dextroamphetamine. (the-medical-dictionary.com)
  • Its parent compound, phenmetrazine, was previously marketed as an appetite suppressant in the 60s and 70s but has since been withdrawn from the market due to concerns of abuse and addiction. (home-chemistry.com)
  • Diet suppressants, cocaine, HIV, and pregnancy are some of the factors that are thought to trigger constriction, or narrowing, in the pulmonary artery. (savvyhealth.com)
  • Pulmonary hypertension has been associated with ingestion of the appetite suppressant aminorex. (wikipedia.org)
  • One reason given behind limiting its use to 12 weeks is drug tolerance, whereby phentermine loses its appetite-suppressing effects after the body adjusts to the drug. (the-medical-dictionary.com)