ApoptosisCaspasesCaspase 3Signal TransductionDNA FragmentationProto-Oncogene Proteins c-bcl-2In Situ Nick-End Labelingbcl-2-Associated X ProteinEnzyme ActivationAntigens, CD95Cells, CulturedCaspase InhibitorsCaspase 9Cell SurvivalCell Line, TumorPhagocytosisMitochondriaApoptotic Protease-Activating Factor 1Jurkat CellsCaspase 8Annexin A5Cytochromes cCell LineApoptosis Regulatory ProteinsNecrosisCell DeathPhosphorylationPhosphatidylserinesBlotting, WesternTumor Cells, CulturedEnzyme InhibitorsProto-Oncogene ProteinsMitogen-Activated Protein KinasesFas Ligand ProteinTumor Suppressor Protein p53Flow Cytometrybcl-X ProteinCysteine Proteinase InhibitorsMAP Kinase Signaling SystemMice, Inbred C57BLAmino Acid Chloromethyl KetonesModels, BiologicalPoly(ADP-ribose) PolymerasesTime FactorsCell ProliferationJNK Mitogen-Activated Protein KinasesProtein-Serine-Threonine KinasesMacrophagesTransfectionStaurosporineCaspase 7Mice, KnockoutMolecular Sequence DataCytochrome c GroupCell DivisionRNA, MessengerCaspase 6Dose-Response Relationship, DrugImmunohistochemistryCaspase 2Cell CycleGene Expression RegulationMembrane Potential, MitochondrialAntineoplastic AgentsMitogen-Activated Protein Kinase KinasesTumor Necrosis Factor-alphaUp-RegulationDown-RegulationMembrane ProteinsRats, Sprague-DawleyMutationProto-Oncogene Proteins c-aktBH3 Interacting Domain Death Agonist ProteinProtein BindingHeLa CellsCell NucleusRNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionHL-60 CellsDNA DamageAmino Acid Sequencebcl-2 Homologous Antagonist-Killer ProteinCarrier ProteinsNeuronsReactive Oxygen SpeciesMembrane GlycoproteinsNF-kappa BInhibitor of Apoptosis ProteinsGenes, bcl-2p38 Mitogen-Activated Protein KinasesCalcium-Calmodulin-Dependent Protein KinasesOxidative StressTranscription Factorsbcl-Associated Death ProteinDNA-Binding ProteinsPhosphatidylinositol 3-KinasesIntracellular Signaling Peptides and ProteinsProteinsAntineoplastic Agents, PhytogenicMicroscopy, Fluorescence