ApoptosisDisease ProgressionCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Caspase 9bcl-2-Associated X ProteinCaspase 8MitochondriaCytochromes cCaspase InhibitorsAntigens, CD95Cell Line, TumorDNA FragmentationSignal TransductionApoptosis Regulatory ProteinsIn Situ Nick-End LabelingApoptotic Protease-Activating Factor 1Cell SurvivalTumor Suppressor Protein p53Fas Ligand ProteinEnzyme ActivationBH3 Interacting Domain Death Agonist ProteinCaspase 7bcl-X ProteinCell Cyclebcl-2 Homologous Antagonist-Killer ProteinBlotting, WesternTumor Cells, CulturedCaspase 2Cell DeathAnnexin A5Cells, CulturedAntineoplastic AgentsMembrane Potential, MitochondrialJurkat CellsProto-Oncogene ProteinsPoly(ADP-ribose) PolymerasesCell LineCell ProliferationCytochrome c GroupFlow CytometryCysteine Proteinase InhibitorsTime FactorsAmino Acid Chloromethyl KetonesGenes, bcl-2Fas-Associated Death Domain ProteinApoptosis Inducing FactorTNF-Related Apoptosis-Inducing LigandImmunohistochemistryInhibitor of Apoptosis ProteinsGene Expression Regulation, NeoplasticRNA, Small InterferingCASP8 and FADD-Like Apoptosis Regulating ProteinMice, Inbred C57BLReactive Oxygen SpeciesNecrosisEnzyme InhibitorsReverse Transcriptase Polymerase Chain ReactionRNA, MessengerReceptors, TNF-Related Apoptosis-Inducing LigandUp-RegulationDown-RegulationTransfectionX-Linked Inhibitor of Apoptosis Proteinbcl-Associated Death ProteinReceptors, Death DomainModels, BiologicalCell DivisionCarrier ProteinsMice, KnockoutDNA DamageDisease Models, AnimalMutationHeLa CellsPhosphorylationDose-Response Relationship, DrugStaurosporineApoptosomesMembrane GlycoproteinsMembrane ProteinsAntineoplastic Agents, PhytogenicNeoplasm ProteinsPhosphatidylserinesCell Cycle ProteinsMyeloid Cell Leukemia Sequence 1 ProteinProstatic NeoplasmsTumor Necrosis Factor-alphaOxidative StressMice, TransgenicCaspase 6Drug Resistance, NeoplasmGene Expression RegulationJNK Mitogen-Activated Protein KinasesBreast NeoplasmsMice, NudeNeoplasmsCaspase 1Cell NucleusIntracellular Signaling Peptides and Proteins