ApoptosisCell CycleCell Cycle ProteinsDNA DamageGenes, cdcCheckpoint Kinase 2G2 PhaseCell Cycle CheckpointsMitosisProtein-Serine-Threonine KinasesAtaxia Telangiectasia Mutated ProteinsS PhaseProtein KinasesDNA RepairG2 Phase Cell Cycle CheckpointsHydroxyureaSpindle ApparatusM Phase Cell Cycle CheckpointsDNA-Binding ProteinsTumor Suppressor Protein p53G1 PhaseNuclear ProteinsGamma RaysDNA ReplicationTumor Suppressor ProteinsMad2 ProteinsSaccharomyces cerevisiae ProteinsSchizosaccharomycesMutationSchizosaccharomyces pombe ProteinsFungal ProteinsSaccharomyces cerevisiaeRadiation, IonizingUltraviolet RaysAtaxia Telangiectasiacdc25 PhosphatasesPhosphorylationChromosomal InstabilityCyclin-Dependent Kinase Inhibitor p21CyclinsCDC2 Protein KinaseCyclin BGenes, FungalCell DivisionRadiation ToleranceIntracellular Signaling Peptides and ProteinsGenomic InstabilityCell Line, TumorSignal TransductionG1 Phase Cell Cycle CheckpointsMicrogliaCell LineHeLa CellsCyclin B1DNA, FungalS Phase Cell Cycle CheckpointsDNA Breaks, Double-StrandedFibroblastsNocodazoleFlow CytometryRetinoblastoma ProteinGene DeletionCell SurvivalModels, BiologicalBase SequenceTumor Cells, CulturedAneuploidyBRCA1 ProteinRepressor ProteinsCells, CulturedHistonesCell ProliferationDNACell NucleusGenes, p53Cyclin-Dependent Kinase 2CDC28 Protein Kinase, S cerevisiaeChromosomes, FungalNeoplasm ProteinsPhenotypeKinetochoresRNA, Small InterferingMethyl MethanesulfonateDNA Repair EnzymesCyclin EGene Expression Regulation, NeoplasticTime FactorsProtein BindingMimosineAmino Acid SequenceCell DeathCDC2-CDC28 KinasesCyclin-Dependent KinasesBlotting, WesternAntineoplastic AgentsNucleic Acid Synthesis InhibitorsDose-Response Relationship, RadiationCalcium-Binding ProteinsCaffeineEnzyme Activation