ApoptosisCaspasesProto-Oncogene Proteins c-bcl-2Caspase 3Apoptosis Regulatory ProteinsDNA Fragmentationbcl-2-Associated X ProteinIn Situ Nick-End LabelingInhibitor of Apoptosis ProteinsCell Line, TumorCell SurvivalSignal TransductionCaspase InhibitorsCaspase 9MitochondriaTumor Suppressor Protein p53Cells, CulturedCaspase 8X-Linked Inhibitor of Apoptosis ProteinCell LineEnzyme Activationbcl-X ProteinTumor Cells, CulturedCytochromes cApoptosis Inducing FactorFas Ligand ProteinBlotting, WesternProto-Oncogene ProteinsAnnexin A5CASP8 and FADD-Like Apoptosis Regulating ProteinFlow CytometryJurkat CellsCell ProliferationMolecular Sequence DataGenes, bcl-2Cysteine Proteinase InhibitorsAmino Acid Chloromethyl KetonesTransfectionPoly(ADP-ribose) PolymerasesCell CycleAntineoplastic AgentsRNA, MessengerNecrosisCell DeathAmino Acid SequenceCell DivisionEnzyme InhibitorsDNA-Binding ProteinsCarrier ProteinsCaspase 7Reactive Oxygen SpeciesPhosphorylationDown-RegulationMembrane ProteinsRNA, Small InterferingApoptotic Protease-Activating Factor 1Mice, Inbred C57BLImmunohistochemistryHL-60 CellsMembrane Potential, MitochondrialTime FactorsDose-Response Relationship, DrugTNF-Related Apoptosis-Inducing LigandNeoplasm ProteinsMembrane GlycoproteinsProtein BindingUp-RegulationStaurosporinebcl-2 Homologous Antagonist-Killer ProteinReverse Transcriptase Polymerase Chain ReactionTumor Necrosis Factor-alphaProteinsCytochrome c GroupBase SequenceDNA DamageHeLa CellsGene Expression RegulationNF-kappa BMutationBH3 Interacting Domain Death Agonist ProteinGene Expression Regulation, NeoplasticMice, KnockoutCell NucleusMyeloid Cell Leukemia Sequence 1 ProteinGene ExpressionTranscription FactorsPhosphatidylserinesbcl-Associated Death ProteinNuclear ProteinsPhagocytosisCaspase 2Proto-Oncogene Proteins c-aktCysteine EndopeptidasesRecombinant ProteinsAntineoplastic Agents, PhytogenicModels, BiologicalOxidative StressRNA InterferenceProtein-Serine-Threonine KinasesCeramides