ApoptosisCaspasesCaspase 3Apoptosis Regulatory ProteinsProto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsDNA FragmentationCell Line, Tumorbcl-2-Associated X ProteinIn Situ Nick-End LabelingSignal TransductionMolecular Sequence DataX-Linked Inhibitor of Apoptosis ProteinCaspase InhibitorsCell SurvivalEnzyme ActivationCaspase 9DNA CleavageCells, CulturedCell LineCaspase 8Apoptosis Inducing FactorMitochondriaCASP8 and FADD-Like Apoptosis Regulating ProteinAmino Acid SequenceTumor Cells, CulturedTumor Suppressor Protein p53Cytochromes cFas Ligand ProteinBlotting, WesternBase SequenceCysteine Proteinase InhibitorsAmino Acid Chloromethyl Ketonesbcl-X ProteinPoly(ADP-ribose) PolymerasesCleavage Stage, OvumCell ProliferationTransfectionAnnexin A5Enzyme InhibitorsFlow CytometryCell CycleProto-Oncogene ProteinsRNA, MessengerMutationCaspase 7Antineoplastic AgentsJurkat CellsRNA CleavageCysteine EndopeptidasesRNA, Small InterferingHydrolysisPhosphorylationCell DivisionSubstrate SpecificityTime FactorsReactive Oxygen SpeciesProtein Processing, Post-TranslationalHeLa CellsCell DeathDose-Response Relationship, DrugProtein BindingRecombinant ProteinsTNF-Related Apoptosis-Inducing LigandEndopeptidasesDown-RegulationMembrane GlycoproteinsHL-60 CellsMembrane ProteinsBinding SitesBH3 Interacting Domain Death Agonist ProteinDNA DamageKineticsTumor Necrosis Factor-alphaMice, Inbred C57BLMembrane Potential, MitochondrialCarrier ProteinsCytochrome c GroupDNAModels, BiologicalProtein Structure, TertiaryPeptide FragmentsUp-RegulationReverse Transcriptase Polymerase Chain Reactionbcl-2 Homologous Antagonist-Killer ProteinNecrosisDNA-Binding ProteinsNF-kappa BStaurosporineGenes, bcl-2RNA InterferenceMice, KnockoutProtein-Serine-Threonine KinasesGene Expression RegulationProto-Oncogene Proteins c-aktCell NucleusMyeloid Cell Leukemia Sequence 1 ProteinSerine EndopeptidasesCaspase 2Gene Expression