MEF2 Transcription FactorsApoptosisMyogenic Regulatory FactorsCaspasesApoptosis Regulatory ProteinsCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCell Line, TumorCell SurvivalApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinSignal TransductionCaspase InhibitorsCaspase 9MitochondriaCaspase 8Cells, CulturedTumor Suppressor Protein p53Enzyme ActivationFas Ligand ProteinTumor Cells, CulturedCytochromes cMADS Domain Proteinsbcl-X ProteinCell LineCell ProliferationBlotting, WesternAnnexin A5Amino Acid Chloromethyl KetonesProto-Oncogene ProteinsCysteine Proteinase InhibitorsCell CycleFlow CytometryTransfectionAntineoplastic AgentsPoly(ADP-ribose) PolymerasesEnzyme InhibitorsReactive Oxygen SpeciesJurkat CellsRNA, Small InterferingTNF-Related Apoptosis-Inducing LigandCell DivisionDown-RegulationDNA-Binding ProteinsTranscription FactorsPhosphorylationCaspase 7Cell DeathHL-60 CellsDose-Response Relationship, DrugMembrane Potential, MitochondrialRNA, MessengerUp-RegulationTumor Necrosis Factor-alphaGenes, bcl-2Gene Expression RegulationReverse Transcriptase Polymerase Chain Reactionbcl-2 Homologous Antagonist-Killer ProteinNecrosisMembrane GlycoproteinsTime FactorsMice, Inbred C57BLCytochrome c GroupDNA DamageProto-Oncogene Proteins c-aktNF-kappa BMyeloid Cell Leukemia Sequence 1 ProteinMice, KnockoutBH3 Interacting Domain Death Agonist ProteinHeLa CellsStaurosporineFibroblastsGene Expression Regulation, NeoplasticMolecular Sequence DataCarrier ProteinsProtein-Serine-Threonine Kinasesbcl-Associated Death ProteinImmunohistochemistryCell NucleusMitogen-Activated Protein KinasesMembrane ProteinsCell DifferentiationOxidative StressAntineoplastic Agents, PhytogenicCeramidesRNA InterferenceReceptors, TNF-Related Apoptosis-Inducing LigandGene ExpressionNeoplasm ProteinsDrug SynergismCaspase 2Protein BindingMutationFas-Associated Death Domain Proteinp38 Mitogen-Activated Protein Kinases