ApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsK562 CellsDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCell Line, TumorCell SurvivalApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsSignal TransductionCaspase 8MitochondriaCells, CulturedFas Ligand ProteinTumor Suppressor Protein p53Enzyme ActivationCytochromes cTumor Cells, Culturedbcl-X ProteinCell LineCell ProliferationAnnexin A5Blotting, WesternAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsProto-Oncogene ProteinsFlow CytometryCell CycleAntineoplastic AgentsEnzyme InhibitorsPoly(ADP-ribose) PolymerasesReactive Oxygen SpeciesCell DivisionTNF-Related Apoptosis-Inducing LigandDose-Response Relationship, DrugJurkat CellsRNA, Small InterferingTransfectionDown-RegulationH(+)-K(+)-Exchanging ATPaseCaspase 7HL-60 CellsMembrane Potential, MitochondrialProto-Oncogene Proteins c-aktTumor Necrosis Factor-alphaCell DeathGenes, bcl-2Time FactorsPhosphorylationUp-Regulationbcl-2 Homologous Antagonist-Killer ProteinMembrane GlycoproteinsNecrosisCytochrome c GroupNF-kappa BMyeloid Cell Leukemia Sequence 1 ProteinMice, Inbred C57BLDNA DamageRNA, MessengerBH3 Interacting Domain Death Agonist ProteinStaurosporineReverse Transcriptase Polymerase Chain ReactionVitamin Kbcl-Associated Death ProteinGene Expression Regulation, NeoplasticHeLa CellsGene Expression RegulationAntineoplastic Agents, PhytogenicImmunohistochemistryCeramidesPhosphatidylinositol 3-KinasesDrug SynergismReceptors, TNF-Related Apoptosis-Inducing LigandOxidative StressProtein-Serine-Threonine KinasesCarrier ProteinsMice, KnockoutNeoplasm ProteinsCaspase 2RNA InterferenceFas-Associated Death Domain ProteinCysteine EndopeptidasesGene ExpressionMitogen-Activated Protein KinasesModels, BiologicalEpithelial CellsApoptotic Protease-Activating Factor 1Rats, Sprague-DawleyMembrane ProteinsMice, NudeDNA-Binding ProteinsFibroblasts