ApoptosisInhibitor of Apoptosis ProteinsGene Expression ProfilingOligonucleotide Array Sequence AnalysisGenes, mycGene ExpressionApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-mycProto-Oncogene Proteins c-bcl-2DNA FragmentationIn Situ Nick-End LabelingCell Line, Tumorbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCell SurvivalApoptosis Inducing FactorSignal TransductionCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsTumor Suppressor Protein p53Caspase 8MitochondriaTumor Cells, CulturedFas Ligand ProteinCells, CulturedEnzyme ActivationCytochromes cCell Proliferationbcl-X ProteinCell LineBlotting, WesternCell CycleAnnexin A5Proto-Oncogene ProteinsCysteine Proteinase InhibitorsAmino Acid Chloromethyl KetonesFlow CytometryAntineoplastic AgentsTransfectionCell DivisionPoly(ADP-ribose) PolymerasesRNA, Small InterferingDown-RegulationEnzyme InhibitorsReactive Oxygen SpeciesTNF-Related Apoptosis-Inducing LigandJurkat CellsGene Expression Regulation, NeoplasticHL-60 CellsRNA, MessengerGenes, bcl-2PhosphorylationCaspase 7Cell DeathMembrane Potential, MitochondrialDose-Response Relationship, DrugTumor Necrosis Factor-alphaUp-RegulationOncogene Protein p55(v-myc)Gene Expression RegulationMembrane GlycoproteinsReverse Transcriptase Polymerase Chain ReactionProto-Oncogene Proteins c-aktbcl-2 Homologous Antagonist-Killer ProteinDNA DamageDNA-Binding ProteinsNecrosisTime FactorsMyeloid Cell Leukemia Sequence 1 ProteinCytochrome c GroupMice, Inbred C57BLNF-kappa BBH3 Interacting Domain Death Agonist ProteinBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsProtein-Serine-Threonine KinasesStaurosporineTranscription FactorsHeLa CellsMice, KnockoutImmunohistochemistryCarrier Proteinsbcl-Associated Death ProteinNeoplasm ProteinsAntineoplastic Agents, PhytogenicReceptors, TNF-Related Apoptosis-Inducing LigandFibroblastsCeramidesMice, TransgenicRNA InterferenceCaspase 2Oxidative StressCell Transformation, NeoplasticDrug SynergismMutationFas-Associated Death Domain ProteinNuclear ProteinsMolecular Sequence Data