ChondrocytesCartilage, ArticularCartilageApoptosisGrowth PlateCells, CulturedCaspasesApoptosis Regulatory ProteinsCaspase 3OsteoarthritisCollagen Type IIProto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsMatrix Metalloproteinase 13AggrecansDNA FragmentationIn Situ Nick-End LabelingSignal TransductionChondrogenesisProteoglycansCell Survivalbcl-2-Associated X ProteinCollagen Type XCell Line, TumorX-Linked Inhibitor of Apoptosis ProteinRNA, MessengerApoptosis Inducing FactorCaspase InhibitorsCaspase 9Cell ProliferationCASP8 and FADD-Like Apoptosis Regulating ProteinCell DifferentiationSOX9 Transcription FactorEnzyme ActivationBlotting, WesternMitochondriaCaspase 8Reverse Transcriptase Polymerase Chain ReactionTumor Suppressor Protein p53Fas Ligand ProteinTumor Cells, CulturedCell DivisionExtracellular Matrix ProteinsCell LineCollagenAnnexin A5Cytochromes cGene Expressionbcl-X ProteinGlycosaminoglycansChondrosarcomaFlow CytometryExtracellular MatrixGene Expression RegulationImmunohistochemistryBone DevelopmentTransfectionDown-RegulationUp-RegulationCysteine Proteinase InhibitorsProto-Oncogene ProteinsCattleDose-Response Relationship, DrugEnzyme InhibitorsTumor Necrosis Factor-alphaAmino Acid Chloromethyl KetonesOsteoarthritis, KneeCell CycleInterleukin-1Interleukin-1betaRNA, Small InterferingChick EmbryoMatrix Metalloproteinase 3Reactive Oxygen SpeciesTime FactorsAntineoplastic AgentsNF-kappa BCartilage DiseasesPoly(ADP-ribose) PolymerasesCaspase 7PhosphorylationCell DeathTissue EngineeringTNF-Related Apoptosis-Inducing LigandCell Culture TechniquesRabbitsJurkat CellsAlginatesMice, Inbred C57BLCollagenasesMice, Knockoutp38 Mitogen-Activated Protein KinasesTransforming Growth Factor betaHyaluronic AcidHypertrophyOsteogenesisGenes, bcl-2HL-60 CellsMembrane GlycoproteinsMembrane Potential, Mitochondrial