ApoptosisClone CellsApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsMolecular Sequence DataDNA FragmentationAmino Acid SequenceCell LineBase SequenceIn Situ Nick-End Labelingbcl-2-Associated X ProteinCell Line, TumorCells, CulturedX-Linked Inhibitor of Apoptosis ProteinCloning, MolecularSignal TransductionCell SurvivalTumor Cells, CulturedApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9MitochondriaCaspase InhibitorsEnzyme ActivationCaspase 8RNA, MessengerTransfectionTumor Suppressor Protein p53Fas Ligand ProteinBlotting, WesternCytochromes cCell DivisionMembrane Proteinsbcl-X ProteinCell CycleCell ProliferationDNAProto-Oncogene ProteinsAnnexin A5Flow CytometryMembrane GlycoproteinsPhosphorylationMicroscopy, ElectronCarrier ProteinsCysteine Proteinase InhibitorsAmino Acid Chloromethyl KetonesMutationFluorescent Antibody TechniqueEnzyme InhibitorsAntineoplastic AgentsKineticsPoly(ADP-ribose) PolymerasesTime FactorsGene ExpressionDNA, ComplementaryProtein BindingRecombinant ProteinsHeLa CellsJurkat CellsReactive Oxygen SpeciesTNF-Related Apoptosis-Inducing LigandGene Expression RegulationDown-RegulationRNA, Small InterferingFibroblastsDose-Response Relationship, DrugMolecular WeightHL-60 CellsCell MembraneSequence Homology, Amino AcidCell DeathCaspase 7Models, BiologicalTumor Necrosis Factor-alphaProteinsMembrane Potential, MitochondrialReverse Transcriptase Polymerase Chain ReactionGenes, bcl-2Transcription, GeneticCytochrome c GroupCell NucleusMice, Inbred C57BLMicrotubulesImmunohistochemistryUp-RegulationCell DifferentiationMicroscopy, FluorescenceRecombinant Fusion ProteinsDNA PrimersMicrotubule-Associated ProteinsDNA-Binding Proteinsbcl-2 Homologous Antagonist-Killer ProteinNecrosisDNA DamageActinsImmunoblottingNF-kappa B