ApoptosisCell Line, TumorIn Situ Nick-End LabelingCell SurvivalAnnexin A5Caspase 3Cell ProliferationAntineoplastic AgentsCell CycleXenograft Model Antitumor AssaysFlow CytometryDrug Screening Assays, AntitumorTumor Cells, CulturedApoptosis Regulatory ProteinsCaspasesDrug SynergismSignal TransductionBlotting, WesternGene Expression Regulation, NeoplasticMice, NudeDrug Resistance, NeoplasmInhibitor of Apoptosis ProteinsProto-Oncogene Proteins c-bcl-2DNA Fragmentationbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsCaspase 8MitochondriaFas Ligand ProteinTumor Suppressor Protein p53Enzyme ActivationCytochromes cCells, Culturedbcl-X ProteinAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsCell LineProto-Oncogene ProteinsPoly(ADP-ribose) PolymerasesEnzyme InhibitorsTNF-Related Apoptosis-Inducing LigandReactive Oxygen SpeciesJurkat CellsTransfectionCell DivisionRNA, Small InterferingCaspase 7HL-60 CellsDown-RegulationMembrane Potential, MitochondrialCell DeathDose-Response Relationship, DrugTumor Necrosis Factor-alphaGenes, bcl-2Phosphorylationbcl-2 Homologous Antagonist-Killer ProteinMembrane GlycoproteinsNecrosisCytochrome c GroupUp-RegulationMyeloid Cell Leukemia Sequence 1 ProteinRNA, MessengerBH3 Interacting Domain Death Agonist ProteinNF-kappa BDNA DamageProto-Oncogene Proteins c-aktTime FactorsStaurosporineReverse Transcriptase Polymerase Chain ReactionMice, Inbred C57BLbcl-Associated Death ProteinAntineoplastic Agents, PhytogenicCeramidesReceptors, TNF-Related Apoptosis-Inducing LigandProtein-Serine-Threonine KinasesCarrier ProteinsMice, KnockoutCaspase 2HeLa CellsOxidative StressImmunohistochemistryFas-Associated Death Domain ProteinNeoplasm ProteinsGene Expression RegulationCysteine EndopeptidasesRNA InterferenceApoptotic Protease-Activating Factor 1Mitogen-Activated Protein KinasesMembrane ProteinsEpithelial CellsGene ExpressionDNA-Binding ProteinsReceptors, Tumor Necrosis FactorCaspase 1Cell NucleusU937 Cells