Proliferating Cell Nuclear AntigenCell ProliferationCell CycleApoptosisCell DivisionCell Cycle ProteinsCell Line, TumorCells, CulturedSignal TransductionCell SurvivalCell DifferentiationCell LineCell Cycle CheckpointsTumor Cells, CulturedRNA, MessengerBlotting, WesternPhosphorylationG1 PhaseFlow CytometryBromodeoxyuridineCaspase 3CaspasesTumor Suppressor Protein p53Apoptosis Regulatory ProteinsProto-Oncogene Proteins c-bcl-2ImmunohistochemistryMitosisRNA, Small InterferingDown-RegulationS PhaseReverse Transcriptase Polymerase Chain ReactionCyclinsMice, Inbred C57BLTransfectionGene Expression RegulationTime FactorsGene Expression Regulation, NeoplasticCyclin-Dependent Kinase Inhibitor p21Cyclin-Dependent Kinase Inhibitor p27Enzyme ActivationDose-Response Relationship, DrugIn Situ Nick-End LabelingCyclin D1Inhibitor of Apoptosis ProteinsCell MovementProtein-Serine-Threonine KinasesTranscription FactorsProto-Oncogene ProteinsMolecular Sequence DataLymphocyte ActivationDNA-Binding ProteinsAntineoplastic AgentsMice, KnockoutFibroblastsUp-RegulationEnzyme InhibitorsKi-67 AntigenGene ExpressionEpithelial CellsRetinoblastoma ProteinRNA InterferenceCell Growth ProcessesProto-Oncogene Proteins c-aktDNA FragmentationMutationNuclear ProteinsT-LymphocytesTumor Suppressor ProteinsDNAModels, BiologicalMice, TransgenicMice, NudeStem CellsG2 Phasebcl-2-Associated X ProteinBase SequenceCell NucleusG0 PhaseG1 Phase Cell Cycle CheckpointsThymidineProto-Oncogene Proteins c-mycCell CountMice, Inbred BALB CCell Transformation, NeoplasticTranscription, GeneticDNA DamageAmino Acid SequenceHeLa CellsProtein BindingNeoplasm ProteinsGene Knockdown TechniquesRats, Sprague-DawleyGene Expression ProfilingCyclin ECyclin-Dependent Kinase 2Cell DeathPhenotypeGrowth InhibitorsGene Expression Regulation, DevelopmentalRecombinant Proteins