AutophagyHeLa CellsApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3PhagosomesMicrotubule-Associated ProteinsProto-Oncogene Proteins c-bcl-2Cell Line, TumorCell SurvivalInhibitor of Apoptosis ProteinsSignal TransductionMitochondriaDNA Fragmentationbcl-2-Associated X ProteinCell LineIn Situ Nick-End LabelingLysosomesCells, CulturedRNA, Small InterferingTransfectionX-Linked Inhibitor of Apoptosis ProteinCaspase InhibitorsApoptosis Inducing FactorEnzyme ActivationTumor Suppressor Protein p53Blotting, WesternTOR Serine-Threonine KinasesCASP8 and FADD-Like Apoptosis Regulating ProteinUbiquitin-Activating EnzymesCaspase 9Caspase 8Cell ProliferationCell DeathTumor Cells, CulturedMembrane ProteinsMolecular Sequence DataCell CycleModels, BiologicalCytochromes cReactive Oxygen SpeciesRNA InterferenceCell NucleusAntineoplastic Agentsbcl-X ProteinFas Ligand ProteinPhosphorylationBase SequenceRNA, MessengerAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsFlow CytometryPoly(ADP-ribose) PolymerasesVacuolesProto-Oncogene ProteinsEnzyme InhibitorsAnnexin A5AdenineDown-RegulationMutationProtein-Serine-Threonine KinasesCarrier ProteinsClass III Phosphatidylinositol 3-KinasesMembrane Potential, MitochondrialCell DivisionGene Expression RegulationProtein BindingDNA-Binding ProteinsTime FactorsTranscription, GeneticDose-Response Relationship, DrugNuclear ProteinsProteinsMicroscopy, FluorescenceProtein TransportTranscription FactorsGene Knockdown TechniquesNecrosisAmino Acid SequenceProto-Oncogene Proteins c-aktCaspase 7DNA DamageUp-RegulationEndoplasmic Reticulum StressJurkat CellsOxidative StressRecombinant Fusion ProteinsMice, Inbred C57BLFibroblastsAdaptor Proteins, Signal TransducingHL-60 CellsMice, KnockoutTNF-Related Apoptosis-Inducing LigandMicroscopy, Electron, TransmissionGreen Fluorescent ProteinsTumor Necrosis Factor-alphaEndoplasmic ReticulumCytoplasmNF-kappa B