Apob100. Medical search. Frequent questions

Apolipoprotein B100 (apoB100) is a protein that plays a role in moving cholesterol around your body. (medlineplus.gov)
Apolipoprotein B100 (apoB100) is a building block of very low-density lipoproteins (VLDLs), intermediate-density lipoproteins (IDLs), and low-density lipoproteins (LDLs). (healthmatters.io)
And it only attaches to the Apolipoprotein B100 (ApoB100) when it's oxidized. (thefatemperor.com)

The following animal models are presently characterized: Akita mouse model, IGF-II/LDLR-/-ApoB100/100 mouse, BB/DR.LepR-/- congenic rats, PDGFBret/ret mouse (a.k.a. retention mouse), ZSF1 rats, DIO mouse, SUR1/E1506K x LDLR-/-ApoB100/100. (lu.se)

An integrated non-steady-state multicompartmental model was constructed to describe the metabolism of apoB48- and apoB100-containing lipoproteins following a fat-rich meal, as well as during prolonged fasting. (scilifelab.se)

Bands corresponding to the expected size of ApoB100 were detected in Human serum samples from five different individuals. (prosci-inc.com)

This article discusses the test used to measure the level of apoB100 in the blood. (medlineplus.gov)

When lipid synthesis is limited in HepG2 cells apoprotein B100 (apoB100) isn't secreted but quickly degraded from the ubiquitin-proteasome pathway. (biobender.com)

Normal plasma apoB48 despite the virtual absence of apoB100 in a compound heterozygote with novel mutations in the MTTP gene. (nih.gov)
In addition, TCDD decreased serum Apob100 (4.4-fold) and Apob48 (2.2-fold) protein levels, suggesting serum lipid clearance and decreased hepatic efflux. (nih.gov)

When lipid synthesis and lipoprotein set up/secretion had been stimulated with the addition of oleic acidity (OA) towards the run after moderate apoB100 was deubiquitinated and its own discussion with sec61β was disrupted signifying conclusion of translocation concomitant with the forming of lipoprotein particles. (biobender.com)

None of the study patients presented ApoB100 gene mutations. (nih.gov)
Mutations (changes) in the gene that directs the body's production of apoB100 can cause a condition called familial hypercholesterolemia . (medlineplus.gov)

13. Multiple factors and pathways involved in hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima Fatty rats. (nih.gov)

In the current presence ABT-869 of OA when MTP lipid-transfer activity was inhibited by the end of pulse labeling apoB100 secretion was abolished. (biobender.com)
MTP catalyzes the original transfer of lipid to nascent apoB100 with following lipoprotein maturation measures happening in the ER and perhaps the Golgi equipment (5 6 Research of cultured major hepatocytes and changed liver organ cells of human being and nonhuman source established that significant control over apoB100 secretion could be exerted in the posttranslational level from the targeting from the nascent proteins to degradation. (biobender.com)
lipoprotein metabolism we and others have shown that most if not all of the degradation of apoB100 that occurs when lipid availability is limited is usually mediated by the ubiquitin-proteasome pathway (9-11). (biobender.com)

To analyze the correlations between inflammation markers and ApoB100 and angiotensin converting enzyme (ACE) gene polymorphism and the severity of coronary artery disease (CAD). (nih.gov)

This article discusses the test used to measure the level of apoB100 in the blood. (medlineplus.gov)

Other disorders that may be associated with high apoB100 levels include atherosclerotic vascular disease such as angina pectoris (chest pain that occurs with activity or stress) and heart attack . (medlineplus.gov)