• 30 pregnant rats on the 14th d were selected, 20 of which were given hydroxyethyl ethylene diamine 150 mg/kg/d by gavage to induce aortic dissection. (ijpsonline.com)
  • Losartan has protective effect on aortic wall of rats with aortic dissection, and the mechanism may be through inhibiting transforming growth factor-beta 1 pathway, which activates downstream phosphoinositide 3-kinase/protein kinase B pathway related proteins, and then inhibits the expansion and progression of aortic dissection. (ijpsonline.com)
  • There is high morbidity and mortality associated with Aortic Dissection (AD), also referred to as AD aneurysm. (ijpsonline.com)
  • Another condition, an aortic dissection, occurs when a portion of the aortic lining tears. (imaginis.com)
  • Aortic dissection accompanies aortic aneurysm in some cases. (imaginis.com)
  • The risk of rupture from aortic dissection is more substantial than from aortic aneurysm. (imaginis.com)
  • Dr. Coselli's research has focused upon the challenges encountered in the surgical treatment of patients suffering from aortic aneurysms, aortic dissection and Marfan syndrome. (bcm.edu)
  • CARbon dioxide flooding to reduce postoperative neurological injury following surgery for acute Type A aortic dissection. (lu.se)
  • hence, attention is increasingly focused on the preoperative identification and surgical management of the aortic valve and subaortic stenosis found in approximately one half of cases. (medscape.com)
  • Three children after surgery for aortic stenosis who were suspected of having EFE were evaluated by echocardiography and MRI. (nih.gov)
  • High-molecular-weight von Willebrand Factor multimer ratio differentiates true-severe from pseudo-severe classical low-flow, low-gradient aortic stenosis. (uib.no)
  • Treatment with prostaglandin E 1 is necessary for neonates with critical aortic stenosis and low cardiac output. (medscape.com)
  • Patients with critical aortic stenosis and low cardiac output require resuscitation with prostaglandin E 1 . (medscape.com)
  • Inotropic drugs, such as dopamine, dobutamine, and epinephrine, are indicated in cases of reduced cardiac output in aortic stenosis. (medscape.com)
  • Loop diuretics such as intravenous furosemide may be used carefully in pediatric patients with reduced cardiac function and/or significant mitral valve insufficiency when associated with severe aortic valve stenosis. (medscape.com)
  • Progression of asymptomatic aortic stenosis identified in the neonatal period. (medscape.com)
  • Congenital valvular aortic stenosis: limited progression during childhood. (medscape.com)
  • Longitudinal assessment of the Doppler-estimated maximum gradient in patients with congenital valvar aortic stenosis pre- and post-balloon valvuloplasty. (medscape.com)
  • Transvascular balloon dilation for neonatal critical aortic stenosis: early and midterm results. (medscape.com)
  • Al-Atassi T, Hynes M, Sohmer B, Lam BK, Mesana T, Boodhwani M. Alterations in Aortic Root Geometry in Bicuspid Aortic Insufficiency Versus Stenosis: Implications for Valve Repair. (ottawaheart.ca)
  • both abdominal and thoracic aortic aneurysms were selected to create 3D animations and applications to educate medical professionals and patients regarding treatment options. (springer.com)
  • Fenestrated endovascular aortic repair (FEVAR) and thoracic endovascular aortic repair (TEVAR) are both tried and tested minimally invasive surgical methods for treating thoracic aortic aneurysms respectively. (springer.com)
  • Alsafi A, Bicknell CD, Rudarakanchana N et al (2014) Endovascular treatment of thoracic aortic aneurysms with a short proximal landing zone using scalloped endografts. (springer.com)
  • Aortic aneurysms are believed to be caused by the gradual weakening of the artery due to atherosclerosis, arterial narrowing and hardening from cholesterol plaque build-up. (imaginis.com)
  • Abdominal aneurysms are most common form of aortic aneurysm, comprising 75% of cases. (imaginis.com)
  • Aortic aneurysms may be further classified as either fusiform (the aneurysm bulges in equal proportions and tapers at the ends, often seen in the lower abnormal aortic section) or saccular (the aneurysm bulges in only a portion of the aortic wall, often seen above the heart). (imaginis.com)
  • The review authors made a thorough search of the medical literature and identified three randomised trials involving a total of 287 participants operated on for high-risk thoracoabdominal aortic aneurysms. (cochrane.org)
  • The specific example shown here employs an activatable fluorescent probe for matrix metalloproteinase-2 (MMP2) to study its uptake in two different rodent models of abdominal aortic aneurysms (AAAs). (jove.com)
  • i.e., thoracoabdominal aortic aneurysms. (bcm.edu)
  • such aneurysms are much less common than abdominal or thoracic aortic aneurysms. (msdmanuals.com)
  • Thoracic Aortic Aneurysms A thoracic aortic diameter ≥ 50% larger than normal is considered an aneurysm (normal diameter varies by location). (msdmanuals.com)
  • Most thoracic aortic aneurysms do not cause symptoms, although some patients. (msdmanuals.com)
  • Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) with technetium-99m ( 99m Tc)-labelled radiotracers. (cadth.ca)
  • 1 The basic principle of radionuclide MPI is to administer a radiopharmaceutical intravenously and image blood flow to the heart muscle (myocardial perfusion), both at rest and under stress. (cadth.ca)
  • Use of a femoral artery for inflow results in retrograde flow through the aorta, while subclavian cannulation permits flow in the conventional direction except to the more proximal aortic arch outflow. (jamanetwork.com)
  • This study was designed to determine whether alteration in distribution to aortic outflow branches occurred on changing from antegrade to retrograde perfusion. (jamanetwork.com)
  • However, the presence of an aberrant right subclavian artery and enough blood flow through the circle of Willis allowed perfusion of the coronary arteries through retrograde carotid and aortic blood flow . (bvsalud.org)
  • Retrograde cerebral perfusion was performed in 16 patients. (medscimonit.com)
  • Ashton HA, Scott R, Bridgewater SG (2002) Randomized clinical trial of screening for abdominal aortic aneurysm in women. (springer.com)
  • Avishay DM, Reimon JD (2020) Abdominal aortic repair. (springer.com)
  • Preoperative, intraoperative, and postoperative images in the case of a patient who received an abdominal aortic endograft and was later diagnosed with Mycobacterium chimaera and Granulicatella adiacens infection, Switzerland, 2014. (cdc.gov)
  • Other causes include hypertension (high blood pressure), Marfan syndrome (genetic connective tissue disease), infectious diseases such as syphilis or tuberculosis, or possibly a genetic predisposition in the case of abdominal aortic aneurysm. (imaginis.com)
  • Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysm. (cdc.gov)
  • Low-density lipoprotein receptor-related protein 5 gene polymorphisms and genetic susceptibility to abdominal aortic aneurysm. (cdc.gov)
  • Proteomics Analysis of Genetic Liability of Abdominal Aortic Aneurysm Identifies Plasma Neogenin and Kit Ligand: The ARIC Study. (cdc.gov)
  • A simplified technique for reversed cerebral perfusion during hypothermic circulatory arrest for transverse aortic arch repair is described. (nih.gov)
  • The theoretical basis is derived from the use of data-processing technology to generate cerebral perfusion images with radionuclides. (spandidos-publications.com)
  • Transcatheter Aortic Valve. (ottawaheart.ca)
  • Al-Atassi, Boodhwani M. Transcatheter aortic valve implantation in nonagenarians: Looking beyond survival. (ottawaheart.ca)
  • Subannular prosthetic valve embolization complicating transapical transcatheter aortic valve implantation: management without sternotomy. (ottawaheart.ca)
  • The varying angle formed by aortic branches in leaving the aorta suggests the possibility that this angle is of importance in determining distribution of aortic outflow, and hence such distribution might be altered by changing direction of aortic flow. (jamanetwork.com)
  • The Sarns-Aortic Cannula is indicated for use In perfusion of the ascending aorta during cardiopulmonary bypass surgery. (fda.gov)
  • Hematoxylin and eosin staining was used to measure the thickness and diameter ratio of the aortic media of mice in each group, Masson staining was used to observe the content of collagen fibers in the aorta of mice in each group, elastic fibers in the aorta of mice in each group were stained, and transforming growth factor-beta and phosphoinositide 3-kinase/protein kinase B pathway protein expression. (ijpsonline.com)
  • Surgery for an aortic aneurysm requires clamping the aorta, the biggest artery in the body. (cochrane.org)
  • To determine the effect of CSFD during thoracic and thoracoabdominal aortic aneurysm (TAAA) surgery on the risk of developing spinal cord injury. (cochrane.org)
  • For this update the Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched May 31 2012) and CENTRAL (2012, Issue 5) for publications describing randomised controlled trials of cerebrospinal fluid drainage for thoracic and thoracoabdominal aortic aneurysm surgery. (cochrane.org)
  • He has dedicated his career to optimizing the care of patients with aortic life-threatening thoracoabdominal aortic aneurisms, or TAAAs, focusing on reducing the risk of neurological and renal complications following TAAA repair. (bcm.edu)
  • Outcomes of 3309 thoracoabdominal aortic aneurysm repairs. (bcm.edu)
  • Dr. Coselli received the award for his work in developing measures to reduce morbidity and mortality in thoracoabdominal aortic aneurysm. (bcm.edu)
  • Focusing upon mortality and major morbidity following thoracoabdominal aortic aneurysm repairs, Dr. Coselli has prospectively evaluated his large contemporary series to identify specific risk factors and develop predictive models for adverse outcomes. (bcm.edu)
  • Selective aortic arch perfusion (SAAP) is an experimental treatment for haemorrhage-induced traumatic cardiac arrest. (wikipedia.org)
  • Surgical video case: antegrade aortic arch perfusion and complete replacement, by Sam Zeraatiannejaddavani Attending Professor of IUMS and CEO of Western Australia RMRC. (medtube.net)
  • Interrupted aortic arch (IAA) is a relatively rare genetic disorder that usually occurs in association with a nonrestrictive ventricular septal defect (VSD) and ductus arteriosus or, less commonly, with a large aortopulmonary window or truncus arteriosus . (medscape.com)
  • [ 1 ] Although most cases occur in normally connected great arteries, interrupted aortic arch can coexist with any ventriculoarterial alignment and also with severe underdevelopment of one ventricle. (medscape.com)
  • Interrupted aortic arch and complete common atrioventricular canal can be observed in the context of coloboma, heart disease, atresia choanae, retarded growth and development and/or CNS anomalies, genital hypoplasia, and ear anomalies and/or deafness (CHARGE) syndrome , which is usually caused by mutations in CHD7 on chromosome 8q12.1. (medscape.com)
  • in these cases, the interrupted aortic arch is usually type B, although cases of type A or type C have also been reported. (medscape.com)
  • [ 9 ] Interrupted aortic arch is the first cardiovascular pattern formation anomaly to be demonstrated to have a genetic basis in both mouse and human. (medscape.com)
  • In addition, two independent lines of evidence suggest that the etiology of many cases of interrupted aortic arch type A is different from the etiology of interrupted aortic arch type B (see below for definition of types). (medscape.com)
  • The variety of associated VSDs is different in the two types of interrupted aortic arch. (medscape.com)
  • approximately three fourths of patients with interrupted aortic arch type B have the deletion, whereas exceedingly few patients with interrupted aortic arch type A have the deletion. (medscape.com)
  • Interrupted aortic arch has been classified into three types (A, B, and C) based on the site of aortic interruption. (medscape.com)
  • In type A interrupted left aortic arch, the arch interruption occurs distal to the origin of the left subclavian artery. (medscape.com)
  • Suprasternal echocardiographic identification of interrupted aortic arch Type B. Upper left: Frontal (coronal) view showing the takeoffs of the innominate artery (InnA) and left common carotid artery (LCCA). (medscape.com)
  • Lower left: Left oblique view showing the LCCA takeoff and no discernible aortic arch. (medscape.com)
  • Interrupted aortic arch and aortic atresia with circle of Willis-dependent coronary perfusion. (bvsalud.org)
  • We present a case of type B interrupted aortic arch and aortic atresia. (bvsalud.org)
  • Background:The purpose of this article is to describe our experience on distal arch and proximal descending aortic aneurysm repair, and to evaluate retrospectively the determinants of mortality and morbidity.Material/Methods: Between 1994 and 2002, 30 patients (mean age 53.4 years) underwent repair of distal arch or proximal descending aortic aneurysm approached through left thoracotomy with deep hypothermic circulatory arrest. (medscimonit.com)
  • Al-Atassi T, Khoynezhad A. Indications for Aortic Arch Intervention. (ottawaheart.ca)
  • In March 2014, a formerly healthy 60-year-old man underwent an elective endovascular aortic repair because of an infrarenal aortic aneurysm. (cdc.gov)
  • He completed his surgical residency at the University of Ottawa Heart Institute where he was the chief resident, followed by a Thoracic Aortic and Endovascular Fellowship at Cedars-Sinai Medical Center in Los Angeles and an Interventional Structural Heart and Minimally Invasive Fellowship at Emory University in Atlanta. (ottawaheart.ca)
  • His multimodal approach to organ protection is now used in many major aortic centers around the world. (bcm.edu)
  • Whole body perfusion has been carried out by using several arteries for the inflow site, most often a femoral or subclavian artery. (jamanetwork.com)
  • It is beneficial in infants with congenital defects that restrict pulmonary or systemic blood flow and who depend on a patent ductus arteriosus to get adequate oxygenation and lower body perfusion. (medscape.com)
  • The carotid and aortic bodies and central chemoreceptors respond to the partial pressure of oxygen (PO 2 ), partial pressure of carbon dioxide (PCO 2 ) and pH of the blood and cerebrospinal fluid. (aafp.org)
  • MRI using perfusion and myocardial delayed enhancement can be useful in establishing the diagnosis. (nih.gov)
  • The surgical procedure entailed complete endoprosthesis removal, closure of the aortic stump below the renal arteries with polypropylene sutures, and omentum coverage. (cdc.gov)
  • In a report appearing in the Journal of Vascular Surgery , he addressed the problem of renal complications on a subsequent study demonstrating that providing cold crystalloid perfusion to the kidneys reduces the risk of renal problems. (bcm.edu)
  • The renal vascular responses to graded Ang II (30, 100, 300, and 1000 ng kg −1 .min −1 ) infusion using A779 or its vehicle were measured at constant renal perfusion pressure. (hindawi.com)
  • The clinical consequence of AD progression is aortic rupture, which seriously endangers the patient's life[ 1 ]. (ijpsonline.com)
  • Blunt trauma that causes significant cardiac injuries (eg, chamber rupture) or severe great vessel injuries (eg, thoracic aortic disruption) frequently results in death before adequate treatment can be instituted. (medscape.com)
  • Patients undergoing major high-risk vascular non-cardiac surgery (including aortic and peripheral vascular surgery). (cadth.ca)
  • An unusual cause of prosthetic aortic valve thrombosis detected by multimodality imaging. (uib.no)
  • New techniques are also being developed which allow first pass perfusion imaging of the heart. (imaginis.com)
  • Brain computed tomography perfusion imaging (CTPI) is also performed for continuous dynamic scanning of the layer in the region of interest (ROI) within a certain time after the intravenous injection of the contrast agent. (spandidos-publications.com)
  • Pseudo-color images of multiple parameters are obtained within minutes of processing the images with perfusion software, in a similar manner to magnetic resonance perfusion imaging (MRPI). (spandidos-publications.com)
  • Aortic valvuloplasty in pediatric patients substantially postpones the need for aortic valve surgery: a single-center experience of 188 patients after up to 17.5 years of follow-up. (medscape.com)
  • The aim of this study was to determine the value of computed tomography perfusion (CTP) parameters, including cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and time-to-peak (TP), in a clinical study of patients with stroke. (spandidos-publications.com)
  • To reduce spinal cord injury and its consequent development of paraplegia or paraparesis, perfusion beyond the location of repair using left heart bypass has been evaluated in a large series of patients. (bcm.edu)
  • Apolipoprotein E e4: A Possible Risk Factor of Intracranial Pressure and White Matter Perfusion in Good-Grade Aneurysmal Subarachnoid Hemorrhage Patients at Early Stage. (cdc.gov)
  • Mortality is high in acute aortic syndrome (AAS), which therefore requires early treatment. (revespcardiol.org)
  • Aortic cannula, 7.0 mm (21 Fr) OD with 3/8" connector, 14" (36 em) long, with X Coating surface coating. (fda.gov)
  • During in-house inspection, Terumo Cardiovascular Systems discovered one Soft-Flow Aortic Cannula with a hole in the tip, just above the suture ball. (fda.gov)
  • This agent establishes patency of the ductus arteriosus and can restore adequate systemic blood flow and the perfusion of vital organs. (medscape.com)
  • Establishing the patency of the ductus arteriosus can restore systemic blood flow and the perfusion of vital organs. (medscape.com)
  • During aortic aneurysm surgery, cross-clamping can lead to inadequate blood supply to the spinal cord resulting in neurological deficit. (cochrane.org)
  • Dr. Al-Atassi is particularly interested in heart valve and aortic surgery, including less invasive operative techniques (such as novel transcatheter technology). (ottawaheart.ca)
  • Patient outcomes have significantly improved and the practice of aortic surgery has changed. (bcm.edu)
  • Left Ventricular Contraction Pattern in Chronic Aortic Regurgitation and Preserved Ejection Fraction: Simultaneous Stress-Strain Analysis by Three-Dimensional Echocardiography. (uib.no)
  • Controlled release metoprolol for aortic regurgitation: a randomised clinical trial. (uib.no)
  • Quantification of aortic regurgitation using high-pulse repetition frequency three-dimensional colour Doppler. (uib.no)
  • Perfusion of the lower limbs' arteries was maintained with an axillo-bifemoral reconstruction using a polytetrafluoroethylene graft ( Figure 1 ). (cdc.gov)
  • The goal of management is early recognition in order to restore tissue perfusion and thereby prevent progression to multisystem organ failure and death. (medscape.com)
  • An IABP may be placed in the emergency department (ED) as a bridge to percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), to decrease myocardial workload, and to improve end-organ perfusion. (medscape.com)
  • Effect Of Aortic Cannulation Depth on Air Emboli Transport during Cardiopulmonary Bypass: A Computational Study. (perfusion.com)
  • Aortic endograft infection (AGI) is a serious complication of aortic repair, and treatment involves prolonged antimicrobial drug therapy and complete or partial graft explantation with subsequent in situ or extra-anatomic arterial reconstruction. (cdc.gov)