Aortic models of cardiac models cardiovascular. Medical search. Frequent questions

Transcatheter are used in the treatment of aortic valve stenosis, which is one of the common cardiovascular disorders which warrant surgical intervention. (medgadget.com)
Mutant 2 (Lox gene mutation): Cardiovascular defects: Supravalvular aortic stenosis (narrowed ascending aorta), Thickened great artery walls, Biventricular hypertrophy, and Pulmonary artery branch stenosis. (jax.org)
High-molecular-weight von Willebrand Factor multimer ratio differentiates true-severe from pseudo-severe classical low-flow, low-gradient aortic stenosis. (uib.no)
and subclinical carotid artery stenosis documented by ultrasound (defined as ≥50% lumen stenosis) and aortic atherosclerotic disease (defined as an abdominal aortic aneurysm). (natap.org)
Severe Aortic Stenosis in a Veteran Population: Treatment Considerations and Survival. (rajgopaldasmd.com)
Objective The management of patients with asymptomatic, severe aortic stenosis (AS) is controversial. (bmj.com)

A 12-year experience of endovascular repair for ruptured abdominal aortic aneurysms in all patients. (oru.se)
He is currently studying the biomechanical progression of aortic aneurysms by modeling the mechanical forces that act on the degenerating vessel wall. (pitt.edu)
He is developing a treatment strategy for abdominal aortic aneurysms by delivering mesenchymal stem cells or their secreted products to the periadventitial side of the aneurysm to inhibit the matrix degradation commonly seen in the disease progression and promote its regeneration. (pitt.edu)
The specific example shown here employs an activatable fluorescent probe for matrix metalloproteinase-2 (MMP2) to study its uptake in two different rodent models of abdominal aortic aneurysms (AAAs). (jove.com)
Genetic mutations/dysregulation affecting Transforming Growth Factor beta (TGFβ) ligands signaling is found in several neonatal, pediatric, and adult patients with cardiovascular complications, including valvular heart disease, cardiomyopathy, cardiac fibrosis, and arterial aneurysms. (sc.edu)

This thesis, in addition to comprehensively validating the 1-D model with structured tree outflow condition and demonstrating disease modelling, uses an alternative to experimental studies, which is free from human and calibration errors, to exhibit the accuracy of the GTF technique. (nottingham.ac.uk)
The most common cardiovascular diseases are coronary artery disease, heart insufficiency, and cerebrovascular disease. (skr.fi)
Many donors have wanted to support medical science or specifically cardiovascular disease research. (skr.fi)
Applications for the cardiovascular disease research grants could be submitted during the Finnish Cultural Foundation's regional funds' application round in January. (skr.fi)
Of the one hundred applications received, some were directed to the normal evaluation of the regional funds, where it was felt they had better chances of success than in the application process meant for bigger cardiovascular disease projects. (skr.fi)
These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) ( http://www.ipccc.net/ ). (jax.org)
Dr. Albers develops mathematical models of physiology, machine learning models, and their associated inference methods to support the extraction and creation of new knowledge from data related to diabetes, to support clinician-centric decision support, and to support patient-centric decision support for chronic disease self-management. (cuanschutz.edu)
Associations with incident chronic kidney disease (CKD), dementia, and mortality were assessed with adjusted Cox models. (bvsalud.org)
METHODS: The multi-ethnic study of atherosclerosis (MESA) is a longitudinal study of 6814 adults without clinical cardiovascular disease (CVD) at enrollment. (bvsalud.org)
Hypertension is the most common disease among many cardiovascular diseases, and HF caused by hypertension is one of the main causes of myocardial remodeling. (researchsquare.com)
Atherosclerosis is the main pathophysiological foundation of cardiovascular disease, which was caused by inflammation and lipid metabolism disorder, along with vascular calcification. (thno.org)
Background Cohort studies have demonstrated associations between calcific aortic valve disease (CAVD) and Lp(a). (medrxiv.org)
An elevated GRS is associated with future cardiac events in a secondary risk setting, but, if coronary artery disease status is known, it does not provide additional prognostic information. (medrxiv.org)
Assessment of left ventricular diastolic function is useful in risk stratification for patients with cardiovascular disease and can provide a diagnostic clue for heart failure with preserved ejection fraction. (medsci.org)
LBBB in children is associated with cardiovascular disease, surgery, or ablation within the left ventricle and is not observed in the general population. (medscape.com)
and how various cutting-edge technologies and models are being employed to study heart biology, uncover disease-related processes, and identify therapeutic targets. (cshlpress.com)
While a big proponent of cardiac CT angiography (CCTA), Leipsic said we still need to follow the guidelines, which includes not using CCTA in the setting of known disease, extremes in calcium scores or in patients with poorly controlled heart rate. (itnonline.com)
Genetically engineered mouse models of human cardiovascular disease provide an opportunity to understand critical pathophysiological mechanisms. (biomedcentral.com)
Genetically engineered mice are useful for mechanistic studies of cardiovascular disease states, which depend, in part, on quantitative phenotypic characterization. (biomedcentral.com)
Since 2000, cardiovascular disease deaths for defensive linemen, after accounting for differences in size, have been similar to other players. (cdc.gov)
PAD ASCVD events, in particular lower limb artery disease, was predominant and requires active diagnosis and intensive management, while controlling modifiable traditional cardiovascular risk factors. (natap.org)
An increased risk of cardiovascular disease (CVD) was reported in patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV), without identifying factors associated with atherosclerotic CVD (ASCVD) events. (natap.org)
Furthermore, recent developments in engineering target-specific and activatable fluorescent probes provide NIRF with high specificity and sensitivity, making it an attractive modality in studying cancer and cardiovascular disease. (jove.com)
Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have increased cardiovascular disease (CVD) risk compared with the general population. (bmj.com)
My research focus is on gaining an understanding of the unique and redundant biological function and properties of the three transforming growth factor beta (TGFβ) ligands and their signaling mechanisms in cardiovascular development and homeostasis and in disease pathogenesis. (sc.edu)
Cardiovascular disease is the number one cause of death and morbidity in the United States. (sc.edu)
The overall goal is to determine the role and the underlying regulatory mechanisms of TGFβ ligands in vivo in development and pathogenesis of calcific aortic valve disease (CAVD). (sc.edu)
The overall goal is to determine the cell-specific role of TGF-beta2 and its downstream mechanisms in development of congenital heart defects and adult aortic and mitral valve disease. (sc.edu)
Sex Differences in Thoracic Aortic Disease and Dissection: JACC Review Topic of the Week. (ottawaheart.ca)
Gut Microbiome in Cardiovascular Disease and Heart Failure A new study investigates the relevance of imidazole propionate, a gut microbial metabolite, to cardiovascular disease and heart failure. (medscape.com)
Clonal Hematopoiesis in Patients With ASCVD A new study provides strong evidence of the significant clinical impact of clonal hematopoiesis of indeterminate potential in patients with atherosclerotic cardiovascular disease. (medscape.com)
Cardiovascular Evaluation and Management of Obese Patients This paper examines the unique clinical challenges which accompany the diagnosis and treatment of cardiovascular disease in persons who are overweight or obese. (medscape.com)
Assessment of coronary artery disease risk in 5463 patients undergoing cardiac surgery: when is preoperative coronary angiography necessary? (who.int)
Overview of Congenital Cardiovascular Anomalies Congenital heart disease is the most common congenital anomaly, occurring in almost 1% of live births ( 1). (msdmanuals.com)
2] A prediction model that and transparency of such risk adjustment models, and to widen uses a `history of coronary heart disease' as a risk factor to predict discussion on the strengths and limitations of risk adjustment models death from an acute myocardial infarction (AMI) is always going based on service claims data. (who.int)
Knowledge of the epidemiology authors of these studies (qualified paediatric of congenital heart disease is the basis on cardiologists) aided by qualified paediatric which investigative efforts will emerge to specialists made the diagnostic decisions identify the causes of cardiac dysmorpho- after carrying out a full physical examina- genesis and afford opportunities to prevent tion, plain chest radiography, electrocardi- them [ 3 ]. (who.int)
1 Infants with critical congenital heart defects (also referred to as critical congenital heart disease [CCHD]) who are discharged from birth hospitals without a diagnosis are at risk for cardiovascular collapse and death. (cdc.gov)

Aim of the study was to find predictors of allocating patients after transcatheter aortic valve implantation (TAVI) to geriatric (GR) or cardiac rehabilitation (CR) and describe this new patient group based on a differentiated characterization. (biomedcentral.com)
For patients having a prohibitive surgical risk, transcatheter aortic valve implantation (TAVI) has been developed as an alternative to the surgical valve replacement. (biomedcentral.com)
Transcatheter market is bifurcated by product into transcatheter mitral valve repair (TMVR) and transcatheter aortic valve replacement (TAVR). (medgadget.com)
Transcatheter aortic valve replacement market share has largest due to continuous advances in the product. (medgadget.com)
End-users in the global transcatheter market include cardiac catheterization laboratory, ambulatory surgical centers (ASCs), and hospitals. (medgadget.com)
Bleeding Events After Transcatheter Aortic Valve Replacement This review provides an in-depth overview of bleeding events after TAVR and their clinical impact, as well as antithrombotic management and its potential influence on bleeding complications. (medscape.com)

Background: Arterial stiffening and peripheral wave reflections have been considered the major determinants of raised pulse pressure (PP) and isolated systolic hypertension, but the importance of cardiac contractility and ventricular ejection dynamics is also recognised. (kcl.ac.uk)

Deep learning and machine learning models provide a reliable, rapid, and effective solution to deal with such challenging diseases in these circumstances. (cdc.gov)
Cardiovascular diseases are widespread in Finland. (skr.fi)
Adjunct professor Katariina Öörni and a research group at the Wihuri Research Institute received €180,000 for research on the reasons for the qualitative characteristics of lipoproteins and research on their effects on the development of cardiovascular diseases. (skr.fi)
One million euros for cardiovascular diseases were collected from 14 donor funds in the areas of ten regional funds, and applications for the grants could be submitted throughout Finland. (skr.fi)
He is also designing a small diameter tissue engineered vascular graft to treat cardiovascular diseases. (pitt.edu)
Heart failure (HF) is the end pathophysiological process of many cardiovascular diseases. (researchsquare.com)
Heart failure (HF) is the most common final pathophysiological process of many cardiovascular diseases, and it poses a serious threat to human life and health. (researchsquare.com)
This issue of Heart Failure Clinics, edited by Dr. Roberto Manfredini, will cover an array of topics related to Chronobiology and Cardiovascular Diseases. (elsevier.ca)
Sex and Circadian Periodicity of Cardiovascular Diseases: Are Women Sufficiently Represented in Chronobiological Studies? (elsevier.ca)
With the growth of genetic engineering, mice have become increasingly common as models of human diseases, and this has stimulated the development of techniques to assess the murine cardiovascular system. (nih.gov)
As a result of improved medical and surgical management of congenital cardiovascular malformations, about 90% of children born with congenital heart diseases now live into neonatal, postnatal and adult stages of life. (sc.edu)
The long term goal also includes an investigation into the role of the three TGFβ ligands in the susceptibility, onset, and progression of adult cardiovascular diseases. (sc.edu)
Nowadays, cardiovascular diseases constitute one of the most important causes of mortality in the world. (edu.sa)
For instance, an estimate of 17.3 million people died in 2008 from cardiovascular diseases. (edu.sa)
11. Non-cardiac concomitant diseases with a life expectancy of less than 1 year (for example, oncological diseases). (who.int)
Doctors use this procedure to diagnose heart diseases after chest pain , sudden cardiac arrest (SCA), or abnormal results from other heart tests such as an EKG or a stress test. (medlineplus.gov)

Among his many contributions, he was influential in the design and creation of a cardiopulmonary (heart-lung) bypass machine and the intra-aortic balloon pump. (pharmaceuticalintelligence.com)

CHD includes a wide range of cardiovascular phenotypes spanning localized anatomical defects to more complex abnormalities with common forms including bicuspid aortic valve (BAV) and Tetralogy of Fallot (TOF). (findaphd.com)

The physiological conditions simulated were the variation in cardiac output and the variation in arterial stiffness while the pathological conditions simulated were abdominal aortic aneurysm and the coarctation of aorta. (nottingham.ac.uk)

For example, arterial hypertension is modeled increasing the arterial resistances of the model. (wikipedia.org)
Methods: We examined the contributions of arterial compliance and ventricular contractility to variations in aortic flow and increased central (cPP) and peripheral (pPP) pulse pressure, and PP amplification (PPa) in normotensive subjects during pharmacological modulation of physiology, in hypertensive subjects, and in silico using a cardiovascular model accounting for ventricular-aortic coupling. (kcl.ac.uk)
Development of an existing non-linear one-dimensional (1-D) mathematical model that can comprehensively compute the propagation of blood in the human arterial network. (nottingham.ac.uk)
Simulation of pulse wave propagation in the entire arterial tree was then undertaken with two different geometries, from a 3-D model and physiological data. (nottingham.ac.uk)
BACKGROUND: A wide variety of different formulae have been used to calculate local arterial stiffness with little external validation in relationship to cardiovascular events. (bvsalud.org)
This study modeled increasing smooth muscle tone as a therapeutic strategy to improve central arterial dysfunction in hypertension using participant-specific simulations. (bvsalud.org)

He is leading various project on tools for bleeding management and resuscitation, as well as heading up research and clinical practice on aortic balloon occlusion (REBOA). (oru.se)
Subcategorizing EHR diagnosis codes to improve clinical application of machine learning models. (cdc.gov)
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. (jax.org)
As Lp(a) is almost entirely genetically determined, with the increasing clinical availability of genetic information, we aimed to determine if Lp(a), when predicted from genetic data, is associated with CAVD and major adverse cardiovascular events (MACE). (medrxiv.org)
The addition of baPWV and PWDC to a clinical model improved the prediction of high E/Ea and LVDD. (medsci.org)
The latest technical advances and trends in computed tomography (CT) and the latest clinical study data were discussed at the Society of Cardiovascular CT (SCCT) 2020 virtual meeting in July. (itnonline.com)
Controlled release metoprolol for aortic regurgitation: a randomised clinical trial. (uib.no)
This talk will present original predictive algorithms suitable for estimating major cardiovascular biomarkers from commonly measured clinical data. (tuc.gr)
She specializes in non-invasive cardiovascular health assessment and develops clinical and digital monitoring tools, driving advancements in machine learning for improved patient management. (tuc.gr)
Her research interests include machine learning, non-invasive health monitoring, clinical language models, digital biomarkers, and physiological ageing. (tuc.gr)
In addition, she is working on biomedical applications in the fields of patient-specific physic-based modelling, synthetic data generation, and enhanced prediction of patient outcomes via multimodal integration of clinical data and language representations. (tuc.gr)
My background is as a cardiovascular physiologist interested in the health and well being of different human populations from elite athletes to clinical groups. (ljmu.ac.uk)
OBJECTIVES: We sought to critically analyze the routine use of conventional coronary angiography (CCA) before noncoronary cardiac surgery and to assess clinical prediction models that might allow more selective use of CCA in this setting. (who.int)
The addition of key condition-specific clinical data points at the time of hospital admission will dramatical y improve model performance. (who.int)

Objective We aimed to investigate whether preoperative serum neutrophil gelatinase-associated lipocalin (sNGAL pre-op ) predicted postoperative acute kidney injury (AKI) during hospitalisation and 1-year cardiovascular and all-cause mortality following adult cardiac surgery. (bmj.com)
Conclusion In a cohort of high-risk adult patients undergoing cardiac surgery, there was an increase in postoperative AKI and 1-year mortality from the first to the third tertile of preoperative serum NGAL. (bmj.com)
The HF model was induced by aortic banding (AB) surgery. (researchsquare.com)
Evaluation of a multi-view autostereoscopic real-time 3D ultrasound system for minimally invasive cardiac surgery guidance. (uib.no)
Journal of Thoracic and Cardiovascular Surgery , 2010 Sep;140(3):606-10. (rajgopaldasmd.com)
The Journal of Thoracic and Cardiovascular Surgery. (ottawaheart.ca)
METHODS: We studied 5463 patients undergoing aortic valve surgery, mitral valve surgery, or septal myectomy with or without coronary artery bypass grafting from 2001 to 2010. (who.int)
Schematic representation of heater-cooler circuits tested for transmission of Mycobacterium chimaera during cardiac surgery despite an ultraclean air ventilation system. (cdc.gov)
Adequate planning for specific patient variables and predictable problems often encountered in cardiac surgery, though essential, cannot fully eliminate the necessity of intervening and even urgently returning to CPB. (medscape.com)
The more than 6.5 million surgical records in this database have helped create surgical risk calculators and have led to improvements in perioperative care for cardiac surgery patients. (medscape.com)
The anesthesiology module now included in the Adult Cardiac Surgery Database (ACSD) component of the STS database, created through a partnership with the Society of Cardiovascular Anesthesiologists (SCA), will only further enhance perioperative care. (medscape.com)
Anesthesiologists will continue to play primary roles in optimizing patients' medical condition and safely guiding them through cardiac surgery with CPB. (medscape.com)
ABSTRACT Acute kidney injury is a serious complication after cardiac surgery. (who.int)
This study was conducted to determine the frequency of acute kidney injury and the associated risk factors following cardiac surgery at Dhahran health centre in eastern Saudi Arabia. (who.int)
All patients who underwent cardiac surgery between June 2005 and December 2008 were included. (who.int)
Acute kidney injury following cardiac surgery is a serious problem among patients in eastern Saudi Arabia. (who.int)
10. The need for concomitant cardiac surgery, except for CABG (for example, valve surgery, aortic repair, etc. (who.int)
Patients who require additional surgery (cardiological or extra-cardiac) for 1 year. (who.int)

In logistic regression models the effect of cardioplegia on 30-day mortality, IABP/ECLS (intraaortic balloon-pump/extracorporal life support) implantation, transient neurological deficit, stroke, renal failure, new-onset atrial fibrillation, and troponin T release was estimated. (minervamedica.it)
Dialysis prolongs life but augments cardiovascular mortality. (frontiersin.org)
The overall 1-year cardiovascular and all-cause mortality was 5.2% (71/1371) and 7.7% (105/1371), respectively. (bmj.com)
There was also an increase in both cardiovascular and all-cause mortality from the first to the third tertile of sNGAL pre-op , linear trend test with adjusted p=0.018 and p=0.013, respectively. (bmj.com)
The adjusted HRs for those in the second and third tertiles of sNGAL pre-op compared with the first tertile were 1.60 (95% CI 0.78 to 3.25) and 2.22 (95% CI 1.13 to 4.35) for cardiovascular mortality, and 1.25 (95% CI 0.71 to 2.22) and 1.91 (95% CI 1.13 to 3.25) for all-cause mortality at 1 year. (bmj.com)
220 ng/L) had an estimated twofold increase risk of cardiovascular and all-cause mortality at 1 year. (bmj.com)
ST-elevation myocardial infarction (STEMI) following successful primary percutaneous coronary intervention (pPCI) is the leading cause of mortality and morbidity worldwide in major adverse coronary events (MACEs) due to mechanical complications, acute heart failure and cardiac shock after successful procedure. (bmj.com)
The cardiac mortality and morbidity were increased in heart failure patients with left ventricular diastolic dysfunction (LVDD) [ 1 , 2 ]. (medsci.org)
We examined the end points of all-cause mortality, cardiac mortality and sudden cardiac death. (bmj.com)
Using a random-effects model, there was a trend towards reduced overall mortality in patients undergoing early AVR compared with a symptom-driven AVR approach (OR 0.54, 95% CI 0.26 to 1.12, p=0.1). (bmj.com)
There was no significant reduction in cardiac mortality or sudden death (OR 0.78, p=0.85, and OR 0.34, p=0.25, respectively). (bmj.com)
Conclusions Although there was a trend towards reduced overall mortality when comparing early AVR in patients with asymptomatic, severe AS to a symptom-driven AVR approach, there was no significant difference in cardiac mortality or sudden death. (bmj.com)
In 2019, Discovery Health published a risk adjustment model to determine standardised mortality rates across South African private hospital systems, with the aim of contributing towards quality improvement in the private healthcare sector. (who.int)

Cross-sectional and longitudinal statistical analyses were performed in addition to Cox hazard modeling for associations with CVD events (myocardial infarction, resuscitated cardiac arrest, stroke, adjudicated angina, and cardiovascular death). (bvsalud.org)
Single Troponin Measurement to Rule Out Myocardial Infarction This review focuses on the potential benefits and limitations of a single-sample high-sensitivity cardiac troponin assay taken in the emergency department in order to exclude acute MI. (medscape.com)

Doppler methods have been used to characterize and evaluate numerous cardiovascular phenotypes in mice and have been particularly useful in evaluating the cardiac and vascular remodeling that occur following transverse aortic constriction. (nih.gov)

Prior to my appointment as PVC in February 2020 I have previously been Associate Dean for Scholarship, Research and Knowledge Transfer in the Faculty of Science, Head of the Research Institute for Sport and Exercise Sciences, interim Director of School of Sport and Exercise Sciences as well as Professor of Exercise and Cardiovascular Physiology. (ljmu.ac.uk)

Mitral annular dynamics are influenced by left ventricular load and contractility in an acute animal model. (uib.no)

13. Gopaldas RR , Huh J, Bakaeen FG, Wang XL, Coselli JS, LeMaire SA and Chu D. The Impact of resident work-hour restrictions on outcomes of cardiac operations. (rajgopaldasmd.com)
We performed a meta-analysis to examine the impact on outcomes of aortic valve replacement (AVR) in patients with severe asymptomatic AS versus a symptom-driven intervention approach. (bmj.com)
Long-Term Survival, Cardiovascular, and Functional Outcomes after Minimally Invasive Coronary Artery Bypass Grafting in 566 Patients. (ottawaheart.ca)

Diagnosis is by ECG, imaging, and cardiac catheterization. (msdmanuals.com)
Cardiac catheterization is a medical procedure used to diagnose and treat some heart conditions. (medlineplus.gov)
You usually have a cardiac catheterization to get the dye into your coronary arteries. (medlineplus.gov)

A biophysical model of human coronary vasculature was used to explain the imaging observations, and highlight causes of coronary BF heterogeneity. (frontiersin.org)
He cited a July paper in JACC Cardiovascular Imaging,[1] which he was a co-author, that cites the dangers of imaging patients in the COVID era and states that it is time to consider making changes to the practice before returning to "normal" imaging workflows. (itnonline.com)
In mice with normal cardiac function, CMR during deep sedation causes significantly less depression of heart rate and ejection fraction than imaging during general anesthesia with isoflurane. (biomedcentral.com)
An unusual cause of prosthetic aortic valve thrombosis detected by multimodality imaging. (uib.no)
European Heart Journal-Cardiovascular Imaging. (uib.no)
The International Journal of Cardiovascular Imaging. (uib.no)
A cardiac CT ( computed tomography ) scan is a painless imaging test that uses x-rays to take detailed pictures of your heart and its blood vessels. (medlineplus.gov)
Cardiac MRI ( magnetic resonance imaging ) is a painless imaging test that uses radio waves, magnets, and a computer to create detailed pictures of your heart. (medlineplus.gov)

Knowledge of the anatomy and electrophysiology of the cardiac conduction system from the atrioventricular (AV) junction to the distal Purkinje fibers is essential to understanding the pathophysiology of left bundle branch (LBB) block (LBBB). (medscape.com)
Journal of Interventional Cardiac Electrophysiology : An International Journal of Arrhythmias and Pacing. (ottawaheart.ca)

A lumped parameter cardiovascular model is a zero-dimensional mathematical model used to describe the hemodynamics of the cardiovascular system. (wikipedia.org)
This mathematical modeling study explores some of the coronary vasculature based causes of myocardial blood flow (BF) heterogeneity. (frontiersin.org)

The prognosis value of apelin-12 in predicting short-term (during hospitalisation) and long-term (2.5 years) major adverse cardiovascular events, respectively, was analysed among patients with estimated glomerular filtration rate exceeding and below 90 mL/min×1.73m 2 . (bmj.com)

To dissect vascular mechanisms, a 3D human vasculature model based on known experimental coronary morphometry and a space filling algorithm was implemented. (frontiersin.org)
METHODS: Participant-specific models of the carotid artery were parameterized from vascular ultrasound measures of nitroglycerin-induced vasodilation in 18 hypertensive veterans. (bvsalud.org)
While these metrics have stood the test of time, offering a snapshot of the current hemodynamic state of the heart and vascular system, there is a widespread acknowledgment among experts that they provide only a partial view of the true physiological intricacies of an individual's cardiovascular system. (tuc.gr)

In vivo , 8-week-aged male LDLR -/- mice were fed a high-fat diet to induce atherosclerosis along with aortic calcification. (thno.org)
Subsequently, the mice tissues were collected to evaluate the effects of GLSP on atherosclerosis, and aortic calcification, and to reveal the underlying mechanism. (thno.org)
We observed GLSP attenuated plaque area and aortic calcification in the mice with early and advanced atherosclerosis. (thno.org)
The purpose of this study was to assess the effects of general anesthesia and a new deep sedation regimen, respectively, on cardiac function in mice as determined by CMR, and to compare them to results obtained in mildly sedated conscious mice by echocardiography. (biomedcentral.com)
In mice with heart failure, the sedation/anesthesia regimen had no clear impact on cardiac function. (biomedcentral.com)
The magnitudes and waveforms of blood velocities from both cardiac and peripheral sites are similar in mice and humans, such that much of what is learned using Doppler technology in mice may be translated back to humans. (nih.gov)
A striking number of cardiovascular defects of humans are modeled in mice with mutation(s) in one or more genes encoding TGFβ ligands. (sc.edu)

Mutant 1: Cardiovascular defects: Right aortic arch (RAA), hypoplastic ascending aorta and brachiocephalic arteries. (jax.org)
On the other hand, they also had to face a huge burden of liability claims along with facing the challenges of several defects that had been found in their already launched models of electric cars. (nativeassignmenthelp.co.uk)

The in-vivo systolic and diastolic pressures were 16.8 ± 0.4 kPa and 9.5 ± 0.4 kPa while the model estimated were 16.89 kPa and 10.94 kPa, respectively, showing excellent agreement. (nottingham.ac.uk)
Neutral impact on systolic and diastolic cardiac function of 2 years of intensified multi-intervention in type 2 diabetes: The randomized controlled Asker and Bærum Cardiovascular Diabetes (ABCD) study. (uib.no)
In particular, we will talk about monitoring tools that advance non-invasive methods for estimating central hemodynamics, including aortic systolic BP and cardiac output, by employing an innovative inverse problem-solving technique and leveraging measurements of cuff pressure and pulse wave velocity. (tuc.gr)

Dr. Bikia is developing new methods to assess cardiovascular health via the prediction of key hemodynamic and cardiac parameters. (tuc.gr)
When designing a risk prediction model, patient-proximate variables with a sound theoretical or proven association with the outcome of interest should be used. (who.int)
In particular, the limitations of machine learning prediction models should be understood, and these models should be appropriately developed, evaluated and reported. (who.int)

Left Ventricular Contraction Pattern in Chronic Aortic Regurgitation and Preserved Ejection Fraction: Simultaneous Stress-Strain Analysis by Three-Dimensional Echocardiography. (uib.no)
With these methods one can measure cardiac filling and ejection velocities, velocity pulse arrival times for determining pulse wave velocity, peripheral blood velocity and vessel wall motion waveforms, jet velocities for the calculation of the pressure drop across stenoses, and left main coronary velocity for the estimation of coronary flow reserve. (nih.gov)
In cardiovascular medicine, therapeutic decisions hinge on easily accessible indicators, such as ventricular ejection fraction (EF) and blood pressure (BP). (tuc.gr)

Sudden Cardiac Death Among Adolescents in the United Kingdom This study investigated various etiologies of sudden cardiac death and their association with physical activity in a large cohort of adolescents, both athletes and non-athletes. (medscape.com)

Large number of cardiac disorders is likely to influence the market growth tremendously. (medgadget.com)
Geriatric population with their vulnerability to cardiac disorders can also facilitate segment growth. (medgadget.com)
Prevalence of various cardiovascular disorders coupled with a well-established healthcare sector can drive the market growth in the region. (medgadget.com)

The lumped parameter model is used to study the hemodynamics of a three-dimensional space (the cardiovascular system) by means of a zero-dimensional space that exploits the analogy between pipes and electrical circuits. (wikipedia.org)

Each heart chamber is modeled by means of the elastances that describe the contractility of the cardiac muscle and the unloaded volume, that is the blood volume contained in the chamber at zero-pressure. (wikipedia.org)
Increased contractility by inotropic stimulation increased peak aortic flow (323.9 ± 52.8 vs. 389.1 ± 65.1 ml/s), and the rate of increase (3193.6 ± 793.0 vs. 4848.3 ± 450.4 ml/s 2 ) in aortic flow, leading to larger cPP (36.1 ± 8.8 vs. 59.0 ± 10.8 mmHg), pPP (56.9 ± 13.1 vs. 93.0 ± 17.0 mmHg) and PPa (20.8 ± 4.8 vs. 34.0 ± 7.3 mmHg). (kcl.ac.uk)
Conclusions: Ventricular contractility plays a key role in raising and amplifying PP, by altering aortic flow wave morphology. (kcl.ac.uk)

Exercise capacity and peak oxygen consumption in asymptomatic patients with chronic aortic regurgitation. (uib.no)

Downstream of the left atrium and ventricle and right atrium and ventricle there are the four cardiac valves: mitral, aortic, tricuspid and pulmonary valves, respectively. (wikipedia.org)

The goal of this studentship proposal is to develop a novel Drosophila model to accelerate the translation of genetic findings to a new mechanistic understanding of CHD and to speed up the initial screening of variants for further study. (findaphd.com)

The components of the cardiac pacemaker and conduction system are not uniform with respect to the function, morphology, and molecular phenotype. (medscape.com)
The four-ring theory describes four conduction system rings within the cardiac tube that differentiate into components of the pacemaker and conduction system. (medscape.com)
The recruitment model assumes some cardiomyocytes are committed early on to the conduction system. (medscape.com)
The specification model postulates that the primary myocardial cells express either conduction system or working myocyte genes. (medscape.com)
His son presented with cardiac conduction disturbance with no congenital heart or skeletal defect. (medscape.com)

One of the biggest weaknesses of the Tesla Company is that it had been facing several types of complications during the manufacturing of the new models of electric cars due to the lack of innovative machines, software, and other technologies on time. (nativeassignmenthelp.co.uk)

Out of these, predictors for assignment to CR or GR after TAVI were identified using a multivariable regression model. (biomedcentral.com)

Cardiovascular magnetic resonance (CMR) provides precise reproducible assessment of cardiac structure and function, but, in contrast to echocardiography, requires that the animal be immobilized during image acquisition. (biomedcentral.com)
Cardiovascular magnetic resonance (CMR) provides quantitatively precise characterization of cardiac structure and function noninvasively in vivo , but can be somewhat hindered by the need to immobilize the animal during image acquisition. (biomedcentral.com)

Rho-kinase inhibition reduced significantly blood pressure, cardiac hypertrophy, myocardial collagen and macrophage infiltration, but not aortic wall hypertrophy. (portlandpress.com)
A significant correlation was found between PBMC Rho-kinase activity and cardiac remodeling, specifically with hypertrophy ( r = 0.51, P ≤0.01), myocardial collagen ( r = 0.40, P ≤0.05) and ED1 immunostaining ( r = 0.48, P ≤0.01). (portlandpress.com)
Cardiac hypertrophy is an important and independent risk factor for the development of cardiac myopathy that may lead to heart failure. (mdpi.com)
The mechanisms underlying the development of cardiac hypertrophy are yet not well understood. (mdpi.com)
Coarctation of the Aorta Coarctation of the aorta is a localized narrowing of the aortic lumen that results in upper-extremity hypertension, left ventricular hypertrophy, and, if severe, malperfusion of the abdominal. (msdmanuals.com)

The splitting of the pulmonary and systemic circulation is not fixed, for example, if the interest of the study is in systemic capillaries, the compartment accounting for the systemic capillaries can be added to the lumped parameter model. (wikipedia.org)

Robust spatio-Temporal registration of 4D cardiac ultrasound sequences. (uib.no)
Cardiovascular Ultrasound. (uib.no)

HCV-related factors did not appear to be associated with the risk of cardiovascular events. (natap.org)

Therefore, many studies have been devoted to modeling the cardiovascular system in order to better understand its behavior and find new reliable diagnosis techniques. (edu.sa)

The major goals of this project are to define cell type specific function and mechanisms of TGF-beta2 in development and progression of thoracic aortic aneurysm and dissection. (sc.edu)

These results were further cemented by carrying out a Bland-Altman analysis as well as a linear regression which demonstrate that the GTF estimated CAP are highly correlated with model-generated CAP with the carotid artery being the most preferable and femoral artery being the least preferable site of PP measurement. (nottingham.ac.uk)
The carotid-femoral pulse wave velocity directly reflected aortic pulse wave velocity [ 4 , 5 ]. (medsci.org)

Anatomy7

Organisms2

Diseases18

Chemicals and Drugs5

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Phenomena and Processes10

Disciplines and Occupations1

Health Care2

Stenosis6

Aneurysms5

Disease37

Transcatheter6

Isolated systolic hyp1

Diseases16

Intra-aort1

Bicuspid aorti1

Abdominal aortic a1

Arterial6

Clinical14

Surgery18

Mortality13

Myocardial infarction2

Phenotypes1

20201

Acute1

Outcomes3

Catheterization3

Imaging8

Electrophysiology2

Mathematical2

Major adverse cardiovascular events1

Vascular3

Mice7

Defects2

Systolic3

Prediction3

Ejection3

Sudden cardi1

Disorders3

Hemodynamics1

Contractility3

Asymptomatic patients1

Tricuspid1

Mechanistic1

Conduction5

Complications1

TAVI1

Magnetic resonance2

Hypertrophy5

Pulmonary1

Ultrasound2

Risk of cardiovascular1

Diagnosis1

Dissection1

Carotid2