Antitumor lead compounds. Medical search. Frequent questions

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Anatomy17

Cell Line, Tumor Tumor Cells, Cultured Cell Line Cells, Cultured HT29 Cells HL-60 Cells Hep G2 Cells HeLa Cells T-Lymphocytes, Cytotoxic CD8-Positive T-Lymphocytes CHO Cells Dendritic Cells Microsomes, Liver Killer Cells, Natural Lymphocytes, Tumor-Infiltrating Vero Cells T-Lymphocytes

Organisms19

Mice, Nude Mice, Inbred BALB C Mice, Inbred C57BL Axinella Porifera Agelas Plants, Medicinal Mice, SCID Cricetinae Plasmodium falciparum Streptomyces Oncolytic Viruses Cricetulus Leishmania donovani Adenoviridae Cercopithecus aethiops Mice, Inbred DBA Rats, Sprague-Dawley Mycobacterium tuberculosis

Diseases17

Leukemia P388 Neoplasms Neoplasms, Experimental Sarcoma 180 Melanoma, Experimental Leukemia L1210 Disease Models, Animal Carcinoma, Lewis Lung Colonic Neoplasms Melanoma Lung Neoplasms Sarcoma, Experimental Fibrosarcoma Neovascularization, Pathologic Mammary Neoplasms, Experimental Carcinoma, Ehrlich Tumor Trypanosomiasis, African

Chemicals and Drugs116

Antineoplastic Agents Small Molecule Libraries Enzyme Inhibitors Antibiotics, Antineoplastic Spiro Compounds Plant Extracts Biological Products Ligands Indoles Azo Compounds Prodrugs Antineoplastic Agents, Phytogenic Thiazoles Furans Heterocyclic Compounds Cancer Vaccines Trypanocidal Agents Sulfur Compounds Antiprotozoal Agents Triterpenes Chalcone Adamantane Antiparasitic Agents Chalcones Pyrans Antiviral Agents Aziridines Volatile Organic Compounds Thiosemicarbazones Nitrofurans Protein Kinase Inhibitors Pyridines Anti-Bacterial Agents Tubulin Modulators Coccidiostats Peptides Angiogenesis Inhibitors para-Aminobenzoates Diterpenes Lactones Coumarins Pharmaceutical Preparations Pyrazoles Alkaloids Sulfonamides Enediynes Benzofurans Pyrroles Quinolines Benzophenones Lead Thiophenes Benzothiazoles Peptides, Cyclic Indicators and Reagents Terpenes Pyrimidines Piperidines Piperazines Triazoles Antimalarials Thiostrepton Recombinant Proteins Oligopeptides Biphenyl Compounds Antigens, Neoplasm Amides Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)Phenols Imidazoles Organotin Compounds Aminopyridines Antitubercular Agents Oxazoles Benzamides Peptide Library Sulfhydryl Compounds Antibodies, Monoclonal Protease Inhibitors Organometallic Compounds Thiourea Aniline Compounds Isoquinolines Benzimidazoles Organophosphorus Compounds Anthelmintics Antifungal Agents Anti-Inflammatory Agents Doxorubicin Organoselenium Compounds Epoxy Compounds Glycosides DNA Nitriles Nitroso Compounds Nitrogen Compounds Anti-Inflammatory Agents, Non-Steroidal Ellipticines Anti-HIV Agents Sulfones Intercalating Agents Cisplatin Anti-Infective Agents Immunotoxins Heterocyclic Compounds, 2-Ring Glutathione Sesquiterpenes Caspase 3 Naphthacenes Anthraquinones Interferon-gamma Camptothecin Naphthoquinones Interleukin-2 Bacterial Proteins Topoisomerase I Inhibitors

Analytical, Diagnostic and Therapeutic Techniques and Equipment46

Drug Screening Assays, Antitumor Drug Design Inhibitory Concentration 50 Xenograft Model Antitumor Assays Drug Evaluation, Preclinical Drug Discovery Combinatorial Chemistry Techniques High-Throughput Screening Assays Models, Molecular Molecular Docking Simulation Neoplasms, Experimental Magnetic Resonance Spectroscopy Neoplasm Transplantation Melanoma, Experimental Parasitic Sensitivity Tests Crystallography, X-Ray Immunotherapy Microbial Sensitivity Tests Chromatography, High Pressure Liquid Administration, Oral Immunotherapy, Adoptive Chemistry Techniques, Synthetic Models, Chemical Drug Stability Transplantation, Heterologous Disease Models, Animal Biological Assay Flow Cytometry Mass Spectrometry Injections, Intralesional Phytotherapy Genetic Therapy Sarcoma, Experimental Blotting, Western Oncolytic Virotherapy Binding, Competitive Tumor Burden Transfection Mammary Neoplasms, Experimental Antineoplastic Combined Chemotherapy Protocols Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Surface Plasmon Resonance Models, Biological Gas Chromatography-Mass Spectrometry Lethal Dose 50

Phenomena and Processes43

Molecular Structure Structure-Activity Relationship Inhibitory Concentration 50 Combinatorial Chemistry Techniques Dose-Response Relationship, Drug Stereoisomerism Cell Survival Cell Proliferation Apoptosis Quantitative Structure-Activity Relationship Drug Synergism Protein Binding Binding Sites Molecular Conformation Kinetics Cell Division Amino Acid Sequence Chemistry Techniques, Synthetic Signal Transduction Biological Availability Catalytic Domain Time Factors Substrate Specificity Cell Cycle Peptide Library Protein Conformation Binding, Competitive Cytotoxicity, Immunologic Cell Death Half-Life Solubility Mutation Phosphorylation Protein Structure, Tertiary Transfection Fermentation Biotransformation Genetic Vectors Chemical Phenomena Enzyme Activation Drug Resistance, Neoplasm Lethal Dose 50 Base Sequence

Disciplines and Occupations4

Drug Design Drug Discovery Chemistry, Pharmaceutical Chemistry

Technology, Industry, Agriculture2

Combinatorial Chemistry Techniques Chemistry Techniques, Synthetic

Information Science6

Molecular Docking Simulation Databases, Chemical Molecular Sequence Data Amino Acid Sequence Computer Simulation Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science

Drug Screening Assays, Antitumor Drug Design Molecular Structure Antineoplastic Agents Structure-Activity Relationship Inhibitory Concentration 50 Xenograft Model Antitumor Assays Drug Evaluation, Preclinical Drug Discovery Small Molecule Libraries Cell Line, Tumor Combinatorial Chemistry Techniques High-Throughput Screening Assays Enzyme Inhibitors Dose-Response Relationship, Drug Models, Molecular Mice, Nude Stereoisomerism Antibiotics, Antineoplastic Leukemia P388 Neoplasms Spiro Compounds Plant Extracts Cell Survival Molecular Docking Simulation Tumor Cells, Cultured Neoplasms, Experimental Biological Products Cell Proliferation Magnetic Resonance Spectroscopy Sarcoma 180 Mice, Inbred BALB C Apoptosis Neoplasm Transplantation Ligands Melanoma, Experimental Quantitative Structure-Activity Relationship Databases, Chemical Indoles Drug Synergism Azo Compounds Cell Line Prodrugs Antineoplastic Agents, Phytogenic Mice, Inbred C57BL Parasitic Sensitivity Tests Protein Binding Thiazoles Furans Heterocyclic Compounds Crystallography, X-Ray Cancer Vaccines Trypanocidal Agents Sulfur Compounds Leukemia L1210 Antiprotozoal Agents Triterpenes Binding Sites Chalcone Axinella Molecular Conformation Adamantane Molecular Sequence Data Antiparasitic Agents Porifera Chalcones Pyrans Antiviral Agents Agelas Immunotherapy Kinetics Aziridines Volatile Organic Compounds Thiosemicarbazones Nitrofurans Protein Kinase Inhibitors Pyridines Anti-Bacterial Agents Tubulin Modulators Coccidiostats Microbial Sensitivity Tests Peptides Chromatography, High Pressure Liquid Angiogenesis Inhibitors para-Aminobenzoates Diterpenes Administration, Oral Cell Division Amino Acid Sequence Lactones Coumarins Plants, Medicinal Pharmaceutical Preparations Pyrazoles Immunotherapy, Adoptive Alkaloids Sulfonamides Chemistry Techniques, Synthetic Enediynes Signal Transduction

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