• A series of 8-hydroxyquinolines are synthesized and their Antitubercular, antifungal, and antibacterial activities are tested. (nepjol.info)
  • In the present study the synthesis, antitubercular, antifungal, and antibacterial activities and structure activity relationship of aryloxypropanolamine substituted 8-hydroxy quinolines are reported. (nepjol.info)
  • A novel series of analogues based on 5-(1-(4-chloro-3-methoxyphenyl)piperidin-4-yl)-4-phenyl-2H-1,2,4-triazol e-3(4H)-thione core have been synthesized and their potential as antibacterial, antifungal and antitubercular agents was examined. (uni-mysore.ac.in)
  • Biological Activity: Antitubercular agent-24 (Compound 1) is an anti-tubercular agent with an extracellular IC 50 of 0.83 μM and an intracellular IC 50 of 0.17 μM against M. tuberculosis H37Rv. (epigenetics-modulation-frontier.com)
  • Treatment trial with antitubercular therapy [ATT] is a common strategy in tuberculosis-endemic countries in case of a diagnostic dilemma between intestinal tuberculosis and Crohn's disease [CD]. (ibdenc.org)
  • Manual de normas y procedimientos técnicos para la bacteriolog'ia de la tuberculosis / Comité Asesor de la OPS/OMS en Bacteriolog'ia de la Tuberculosis. (who.int)
  • Comité Asesor de la OPS/OMS en Bacteriolog'ia de la Tuberculosis. (who.int)
  • Case Report: Pulmonary tuberculosis and raised transaminases without pre-existing liver disease- Do we need to modify the antitubercular therapy? (ox.ac.uk)
  • All compounds 3a-e were also evaluated as antitubercular agent against M. tuberculosis H37Rv by MABA method. (ijps.ir)
  • Synthesis and Structure-Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents. (medchemexpress.cn)
  • The unregulated use of antitubercular drugs in therapy for years has resulted in multidrug-resistant TB. (uel.ac.uk)
  • Furthermore, recent advances and the clinical trial status of the antitubercular drugs are summarized. (uel.ac.uk)
  • This chapter will help the readers to get a comprehensive overview of antitubercular drugs. (uel.ac.uk)
  • He was treated with debridement, intravenous voriconazole, and antitubercular drugs. (amrita.edu)
  • We administered antitubercular drugs alone and in combination with fruit extract of Lagenaria siceraria (EELS 100mg/kg and EELS 200mg/kg) in healthy albino rats by oral route for 15 days. (ijbcp.com)
  • Ethanolic extract of Lagenaria siceraria fruit possesses significant hepatoprotective and antioxidant activity in antitubercular drugs induced hepatotoxicity. (ijbcp.com)
  • Many clinicians including the authors have treated such cases with modified liver friendly regimens in fear of increasing the hepatotoxicity with standard antitubercular drugs. (ox.ac.uk)
  • Antitubercular drug induced hepatotoxicity is mediated through oxidative and free radical damage to hepatocytes. (ijbcp.com)
  • Results indicated that title compounds were showed moderate to good anticonvulsant activities but less antitubercular activity. (ijps.ir)
  • Antitubercular agent-39 is active against drug-resistant strains and drug-susceptible clinical isolates. (medchemexpress.cn)
  • Compound 3d was showed highest antitubercular activity, with 12.5µg/ml MIC value. (ijps.ir)
  • IBP demonstrated specific antitubercular activity, while carprofen was the most selective agent among the 2-arylpropanoic class. (uea.ac.uk)
  • Antitubercular agent-39 inhibits Mtb strain H37Rv with a MIC less than 1 μM [1] . (medchemexpress.cn)
  • Antitubercular agent-39 (Compound P1) is a potent antitubercular agent. (medchemexpress.cn)
  • Results: IBP showed antitubercular properties while carprofen was the most potent among the 2-arylpropanoic class. (uea.ac.uk)
  • How anemia impacts systemic inflammation in PTB patients undergoing antitubercular therapy (ATT) is not fully understood. (fiocruz.br)
  • Crohn's disease patients diagnosed after a trial with antitubercular therapy had an unfavourable long-term disease course with higher rate of stricture formation and less chance of remaining free of surgery. (ibdenc.org)
  • Further research is required in this regard, but the presence of transaminitis with no obvious common underlying etiology may not warrant a modification of standard antitubercular regimen. (ox.ac.uk)
  • 4. Conclusions Within this scholarly research, the function of fucoxanthin as an antitubercular molecule continues to be explored. (forgetmenotinitiative.org)
  • Results of search for 'su:{Antitubercular agents. (who.int)
  • The quest for the holy grail: new antitubercular chemical entities, targets and strategies. (tbdrugaccelerator.org)
  • We describe herein the identification, development and characterization of SQ109 as a promising new antitubercular drug. (nih.gov)