• Aripiprazole, a new agent whose proposed mechanism(s) of action differs from that of other agents, has been shown in placebo-controlled comparative trials in bipolar patients to be an effective and well tolerated treatment option for this patient group. (elsevier.com)
  • Amisulpride's superiority in acute psychosis for global and negative symptoms when compared with conventional antipsychotics must be qualified. (bmj.com)
  • The present data indicate that a three to seven day trial of antipsychotics may be sufficient for making phannacotherapy decisions as such a trial demonstrates a diagnostic efficiency similar to other predictive tests employed in clinical medicine. (elsevier.com)
  • While atypical antipsychotics are associated with a lower risk of tardive dyskinesia, extrapyramidal side effects, and more favorable effects on cognitive deficits and negative symptomatology in schizophrenic patients compared to typical or first generation antipsychotic agents, they are not without risks. (allenpress.com)
  • Two SNPs in GRM7 (rs2069062 and rs2014195) were significantly associated with antipsychotic response in candidate gene analysis, as were two SNPs in the human glutamate receptor delta 2 ( GRID2) gene (rs9307122 and rs1875705) in genome-wide association analysis. (nature.com)
  • Lithium is considered a first-line agent for long-term prophylaxis in bipolar illness, especially for classic bipolar disorder with euphoric mania. (medscape.com)
  • Results Guidelines recommend lithium or valproate as first-line treatments for mania, and antipsychotic agents only as 'adjuncts' for agitation, dangerous behaviour or psychosis. (rcpsych.org)
  • Clinicians should exercise caution when prescribing antipsychotics to patients with COPD and avoid high doses if possible. (nih.gov)
  • Another study, which analyzed Medicaid data from San Diego County from 1998 to 2000, shows that less than one-half of patients are adherent and persistent with antipsychotic therapy, with large numbers taking too few doses and about one-fifth of patients having their prescriptions refilled too frequently. (pharmacist.com)
  • Metabolic adverse effects are particularly problematic with atypical antipsychotics, even at doses lower than those used to treat FDA-approved indications. (allenpress.com)
  • The availability of the newer agents may represent an opportunity to reduce the incidence of tardive dyskinesia and to gain better management of comorbid substance abuse and aggression among schizophrenic patients. (elsevier.com)
  • Cost-effectiveness analysis of schizophrenic patient care settings: impact of an atypical antipsychotic under long-acting injection formulation]. (qxmd.com)
  • brand names Clotepin, Clopiben), also known as octoclothepin or octoclothepine, is an antipsychotic of the tricyclic group which was derived from perathiepin in 1965 and marketed in the Czech Republic by Spofa in or around 1971 for the treatment of schizophrenic psychosis. (wikipedia.org)
  • However, data on LAIs has been mixed, with some studies finding that they are more effective and tolerable than oral antipsychotics, and others finding the contrary. (hindawi.com)
  • They also suggest that LAIs reduce risk of relapse versus oral antipsychotics in schizophrenia outpatients when combined with quality psychosocial interventions. (hindawi.com)
  • Is injectable or oral administration of antipsychotic agents more effective for schizophrenia? (medscape.com)
  • RYANODEX ® ( NDC 42367-540-32 ) is available in 20 mL vials containing a sterile lyophilized mixture of 250 mg dantrolene sodium for reconstitution with 5 mL sterile water for injection USP (without a bacteriostatic agent) to yield an orange colored injectable suspension. (rxlist.com)
  • One possibility for the disparate results may be that some studies administered different antipsychotics in the oral and injectable form. (hindawi.com)
  • Objectives To describe factors associated with initiating antipsychotics and patterns of persistence to antipsychotic therapy in a large cohort of adults with intellectual and developmental disabilities. (bmj.com)