DiseasesChemicals and DrugsPsychiatry and PsychologyPhenomena and Processes
BenztropineTabletsAntiparkinson AgentsMazindolClopenthixolLevodopaDopamine Plasma Membrane Transport ProteinsDyskinesiasTropanesDopamine Uptake InhibitorsCocaineParkinson DiseaseDyskinesia, Drug-InducedBenserazideMPTP PoisoningBenzamidesDopamine AgonistsPiperazinesTrihexyphenidylParkinsonian DisordersPiribedilPyrimidinesPergolideCycloheptanesTablets, Enteric-CoatedMotor Activity1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineCatalepsyDose-Response Relationship, DrugBasal Ganglia DiseasesParkinson Disease, Secondary
Found in atropine and diphenhydramineAnticholinergicCumulative actionStructuralCellulosePatientsWhiteDisease
Found in atropine and diphenhydramine1
  • Benztropine Mesylate is a synthetic compound containing structural features found in atropine and diphenhydramine. (nih.gov)
Anticholinergic6
  • Benztropine mesylate possesses both anticholinergic and antihistaminic effects, although only the former have been established as therapeutically significant in the management of parkinsonism. (nih.gov)
  • When benztropine mesylate is given concomitantly with phenothiazines, haloperidol, or other drugs with anticholinergic or antidopaminergic activity, patients should be advised to report gastrointestinal complaints, fever or heat intolerance promptly. (nih.gov)
  • Paralytic ileus, hyperthermia and heat stroke, all of which have sometimes been fatal, have occurred in patients taking anticholinergic-type antiparkinsonism drugs, including benztropine mesylate, in combination with phenothiazines and/or tricyclic antidepressants. (nih.gov)
  • Benztropine is a centrally acting anticholinergic agent with antihistaminic properties resulting from the combination of the tropine portion of the atropine molecule and the benzohydryl portion of diphenhydramine. (sgpharma.com)
  • Animal studies have indicated that anticholinergic activity of benztropine is approximately half that of atropine, while antihistaminic activity approaches that of pyrilamine. (sgpharma.com)
  • BENZTROPINE MESYLATE TABLETS USP is a powerful anticholinergic agent which is mainly effective in relieving tremor and rigidity. (sgpharma.com)
Cumulative action2
  • Since benztropine mesylate has cumulative action, continued supervision is advisable. (nih.gov)
  • Because of cumulative action of BENZTROPINE MESYLATE TABLETS USP, therapy should be initiated with a low dose which is increased gradually at five or six-day intervals to the smallest amount necessary for optimal relief. (sgpharma.com)
Structural1
  • Since benztropine mesylate contains structural features of atropine, it may produce anhidrosis. (nih.gov)
Cellulose2
  • Each tablet contains the following inactive ingredients: dibasic calcium phosphate anhydrous, lactose monohydrate, lactose anhydrous, microcrystalline cellulose, cornstarch, talc and hydrogenated vegetable oil. (nih.gov)
  • It starts with the precise ingredients of themedicine, including the active ingredient, the drug, and the extracontents that hold it together as a tablet or capsule, such as maizestarch, gelatine, cellulose and colourings. (findmedarticle.com)
Patients1
  • BENZTROPINE MESYLATE TABLETS USP often is helpful in patients who have become unresponsive to other agents. (sgpharma.com)
White3
  • BENZTROPINE MESYLATE TABLETS USP are white coloured, circular, biconvex tablets with break line on one side and "SGP" embossed on the other side. (sgpharma.com)
  • Ondansetron by Sun Pharmaceutical Industries, Inc. is a white oval tablet orally disintegrating about 13 mm in size, imprinted with 241. (naturebrands.eu)
  • Ondansetron by Rpk Pharmaceuticals, Inc. is a white rou tablet orally disintegrating about 7 mm in size, imprinted with 7;e. (naturebrands.eu)
Disease1
  • Benztropine antagonises the effect of acetylcholine, decreasing the imbalance between the neurotransmitters acetylcholine and dopamine, which may improve the symptoms of early parkinson's disease. (sgpharma.com)