• Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. (wikipedia.org)
  • Chemically, nitazoxanide is the prototype member of the thiazolides, a class of drugs which are synthetic nitrothiazolyl-salicylamide derivatives with antiparasitic and antiviral activity. (wikipedia.org)
  • Additionally, antibacterial and antifungal agents that can also be used for treatment of protozoal infections, such as the 5-nitroimidazoles, trimethoprim-sulfamethoxazole, azithromycin, and amphotericin, are not discussed in detail here, but their general indications for parasitic infections are shown in Tables 1 and 2. (monash.edu)
  • As a potential antileukemic agent, ivermectin induced cell death at low micromolar concentrations in acute myeloid leukemia cell lines and primary patient samples preferentially over normal hematopoietic cells. (ashpublications.org)
  • As an antiparasitic, ivermectin binds and activates chloride ion channels in nematodes, so we tested the effects of ivermectin on chloride flux in leukemia cells. (ashpublications.org)
  • Ivermectin is an anti-parasitic agent that has shown promise against the virus in vitro. (biovista.com)
  • Ivermectin is a potent antiparasitic drug and the first commercially available member of a new class of drugs (macrocyclic lactones) that has been approved for human use. (elsevier.com)
  • To identify known drugs with previously unrecognized anticancer activity, we compiled and screened a library of such compounds to identify agents cytotoxic to leukemia cells. (ashpublications.org)
  • Zimecterin® Paste is potent antiparasitic agent that is neither a benzimidazole nor an organophosphate. (sstack.com)
  • Emerging resistance among parasites, lack of effective antiparasitic vaccines, and the enormous burden of disease worldwide also pose challenges to the effective management of parasitic infections. (monash.edu)
  • Objective: This article reviews the chemistry of the microtubule inhibitors in current use and under investigation as antiparasitic agents, their activities against the major parasites and their mechanisms of action. (dit.ie)
  • Other major antiprotozoal drugs are also reviewed, including those used for malaria, infections with gastrointestinal protozoa, leishmaniasis, and trypanosomiasis, but an exhaustive list of all antiparasitic drugs is not included. (monash.edu)
  • Throughout this chapter, we indicate which antiparasitic drugs are currently approved by the U.S. Food and Drug Administration (FDA). (monash.edu)
  • Antiparasitic drugs are the mainstays of control of most of these diseases, but in many cases current therapies are inadequate and in some the situation is deteriorating because of drug resistance. (dit.ie)
  • New understanding from functional genomics, structural biology and microtubular imaging will help accelerate the development of completely novel antiparasitic drugs targeting microtubules. (dit.ie)
  • Antibiotics manufacturer / supplier, Antiparasitic Drugs, etc. (g-housepharma.com)
  • Resistance to antiparasitic agents and drug susceptibility testing are dealt with in separate chapters. (monash.edu)
  • Another agent, nitazoxanide, has both anthelmintic and antiprotozoal activity and is also discussed. (monash.edu)
  • However, the lack of financial incentives to develop new agents is a major limitation to the future of antiparasitic chemotherapy. (monash.edu)
  • The Antiparasitic Agents market report addresses forecast and growth patterns by company, regions and type or application from 2017 to 2021. (medgadget.com)
  • Antiparasitic Artemether Injection used for the treatment of anti chloroquine malaria and pernicious malaria. (g-housepharma.com)
  • Tizoxanide, an active metabolite of nitazoxanide in humans, is also an antiparasitic drug of the thiazolide class. (wikipedia.org)
  • Microtubules as Antiparasitic Drug Targets. (dit.ie)
  • This chapter focuses on the mechanisms of action, pharmacology, clinical utility, and adverse effects of common first-line antiparasitic therapies and newer drug alternatives. (monash.edu)
  • Efficient and quick results of kill agent for plasmodium erythrocytic stage. (g-housepharma.com)
  • Rotavirus is the most common infectious agent associated with diarrhea in the pediatric age group worldwide. (wikipedia.org)
  • Tribendimidine is a promising new agent for treatment of liver flukes (clonorchiasis and opisthorchiasis), but trials are still under way, and it has not yet been approved for use, so it is not discussed. (monash.edu)
  • This antimicrobial was initially classified as an antiparasitic agent because of its activity against Taenia saginata and Hymenolepis nana. (ack1inhibitor.com)
  • Several important areas are covered in this Antiparasitic Agents market research report. (medgadget.com)
  • The Antiparasitic Agents market report provides important statistics on the existing state of the said market. (medgadget.com)
  • Antiparasitic agents are important both for therapy of infected individual patients and for control of parasitic infections at the community level. (monash.edu)
  • Specifically, we exclude discussion of agents without a first-line indication or that are recommended only in special situations, such as furazolidone in children. (monash.edu)
  • This section of the market research report includes analysis of major raw materials suppliers, manufacturing equipment suppliers, major players of the Antiparasitic Agents industry, key consumers, and supply chain relationship. (medgadget.com)
  • The Antiparasitic Agents market provides detailed market segment level data on the international market. (medgadget.com)
  • In this introductory section, the Antiparasitic Agents market research report incorporates analysis of definitions, classifications, applications and industry chain structure. (medgadget.com)
  • The report starts with a basic Antiparasitic Agents market overview. (medgadget.com)
  • Antiparasitic Agents market report helps the companies to better understand the market trends and to grasp opportunities and articulate critical business strategies. (medgadget.com)
  • Price, cost, and gross analysis of the Antiparasitic Agents market is also included in this section. (medgadget.com)
  • Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases, such as those caused by helminths, amoeba, ectoparasites, parasitic fungi, and protozoa, among others. (wikipedia.org)
  • The last group of patents consists of carboxamidines and inhibitors of nucleoside transporters with potential antiparasitic effect. (archives-ouvertes.fr)
  • Another agent, nitazoxanide, has both anthelmintic and antiprotozoal activity and is also discussed. (monash.edu)
  • Nitazoxanide is the only broad-spectrum antiparasitic drug that has been approved in the United States for treatment of cryptosporidiosis. (cdc.gov)
  • Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. (wikipedia.org)
  • Tizoxanide, an active metabolite of nitazoxanide in humans, is also an antiparasitic drug of the thiazolide class. (wikipedia.org)
  • Nitazoxanide [NTZ: 2-acetyloxy-N-(5-nitro-2-thiazolyl)benzamide] is a thiazolide antiparasitic agent with excellent activity against a wide variety of protozoa and helminths. (wikipedia.org)
  • Additionally, antibacterial and antifungal agents that can also be used for treatment of protozoal infections, such as the 5-nitroimidazoles, trimethoprim-sulfamethoxazole, azithromycin, and amphotericin, are not discussed in detail here, but their general indications for parasitic infections are shown in Tables 1 and 2. (monash.edu)
  • These studies demonstrate that atovaquone has pronounced in vitro and in vivo antifungal activity against filamentous fungi by disrupting both metal homeostasis and mitochondrial function, and therefore has potential as a novel antifungal agent. (arvojournals.org)
  • Among the patents disclosed recently, only iminoribitol derivatives have documented antiparasitic activities, especially against nucleoside N-hydrolases (NH), purine nucleoside phosphorylase (PNP) and also against 5′-deoxy-5′-methylthioadenosine phosphorylase (MTAP), an enzyme at the border of polyamine biosynthesis and purine salvage. (archives-ouvertes.fr)
  • Together with other significant structural differences, this provides a possible explanation of the lower affinity of the parasite ENR enzyme family for aminopyridine-based inhibitors, suggesting that an effective antiparasitic agent may well be distinct from equivalent antimicrobials. (strath.ac.uk)
  • The aim of this study was to evaluate the toxicity of parasiticides agent, antimicrobials agent and insecticides on A. franciscana to establish Predicted No-Effect Concentration (PNEC) on marine organisms and obtain guidance levels for the protection of aquatic life. (edu.pe)
  • In this paper, we aim to present an updated overview of in vitro and in vivo studies that show the significant therapeutic properties of the crude extracts and phytochemicals derived from H. sabdariffa as antimicrobial, antiparasitic, and anticancer agents. (prolekare.cz)
  • Parasite biochemical pathways are sufficiently different from the human host to allow selective interference by chemotherapeutic agents in relatively small doses. (medscape.com)
  • Here we report that guanabenz, an FDA-approved drug that interferes with translational control, has antiparasitic activity against replicative stages of Toxoplasma and the related apicomplexan parasite Plasmodium falciparum (a malaria agent). (asm.org)
  • Early antiparasitics were ineffective, frequently toxic to patients, and difficult to administer due to the difficulty in distinguishing between the host and the parasite. (wikipedia.org)
  • Its antiparasitic mechanism of action is through binding selectively to certain ion channels present in invertebrate nerve and muscle cells but not present in mammals. (fiercebiotech.com)
  • In particular, antibacterial agents are incredibly important worldwide, with the emergence of multi-drug resistant bacteria. (rsc.org)
  • Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA. (labome.org)
  • Rotavirus is the most common infectious agent associated with diarrhea in the pediatric age group worldwide. (wikipedia.org)
  • The goal of antiparasitics is destruction of the infectious parasitic agents. (imedix.com)
  • Eurytrema coelomaticum is a digenean flatworm of ruminants that is the causative agent of eurytrematosis, a disease of veterinary health concern. (usda.gov)
  • In case of identification of the causative pathogen, an antibiotic or an anti-parasitic agent may be used. (news-medical.net)
  • The flagellated protozoan Trypanosoma cruzi is the etiologic agent of American trypanosomiasis (Chagas' disease), a major public health problem in many Latin American countries, with an estimated 15 million people infected. (asm.org)
  • Resistance to antiparasitic agents and drug susceptibility testing are dealt with in separate chapters. (monash.edu)
  • Resistance to antiparasitics has been growing concern, especially in veterinary medicine. (wikipedia.org)
  • WHO HQ Library catalog › Results of search for 'su:{Antiparasitic agents. (who.int)