Antioxidant effect effects anticancer drugs or radiation. Medical search. Frequent questions

These products may not be prescription drugs, but they do have a powerful ability to interact with chemotherapy, radiation treatments, and anti-cancer medicines. (issels.com)
Could decrease the effectiveness of chemotherapy - or increase the effects, with toxic results. (issels.com)
Antioxidant properties may interfere with chemotherapy and radiation. (issels.com)
May interfere with certain drugs or chemotherapy. (issels.com)
Surgery, chemotherapy, and radiation therapy are still the main treatment methods, but each method has its limitations and risks. (frontiersin.org)
Reducing hypoxia may have sensitizing effects on radiotherapy, chemotherapy, phototherapy, acoustic therapy and so on. (frontiersin.org)
To justify the continued funding and availability of drugs used in cytotoxic chemotherapy, a rigorous evaluation of the cost-effectiveness and impact on quality of life is urgently required. (connersclinic.com)
Although taking an antioxidant pill sounds harmless, Cianciotta, a clinical dietitian who works with cancer patients at NewYork-Presbyterian Hospital in New York City, knows well that this popular dietary supplement can interfere with a patient's radiation or chemotherapy. (webmd.com)
This group of enzymes plays a key role in metabolizing drugs, including chemotherapy and immunotherapy agents. (webmd.com)
Some studies suggest that antioxidant supplements may lessen the effects of radiation and chemotherapy, although the evidence is mixed . (webmd.com)
If you are on prescription drugs (excluding chemotherapy, because this protocol is synergistic with chemotherapy and makes chemotherapy more effective and less damaging), do NOT use MSM until after you talk to your pharmacist and physician about using high doses of MSM (2 or 3 TABLEspoons of the crystals a day) with your prescription drugs. (infiniteunknown.net)
Cordyceps cicadae mushroom treatment prevented testicular damage and tumors caused by the chemotherapy drug cisplatin via inhibition of oxidative stress and inflammation in rats. (greenmedinfo.com)
In a clinical study of 105 cancer patients undergoing chemotherapy or radiation treatments, a combination of reishi mushroom extract and geraniums improved immunity and fought the cancer and secondary infections that could have compromised treatment and health. (greenmedinfo.com)
Current treatments for gliomas use chemotherapy, radiotherapy, tyrosine kinase inhibitors, monoclonal antibodies and surgery, but each of the treatment strategies has several serious side effects. (frontiersin.org)
Surgery to the extent that this is feasible in terms of safety, followed by involved-field radiation therapy and concomitant and maintenance chemotherapy with temozolomide, has set the standard of care since 2005. (frontiersin.org)
The chemotherapy drug cisplatin may cause excessive loss of magnesium and potassium in the urine. (peacehealth.org)
The chemotherapy drug cisplatin may cause kidney damage, resulting in depletion of calcium and phosphate. (peacehealth.org)
In a double-blind study, Japanese researchers found that the combination of vitamin E , vitamin C, and N-acetyl cysteine (NAC) -all antioxidants-protected against chemotherapy-induced heart damage without interfering with the action of the chemotherapy. (peacehealth.org)
A comprehensive review of antioxidants and chemotherapy leaves open the question of whether supplemental antioxidants definitely help people with chemotherapy side effects, but it clearly shows that antioxidants need not be avoided for fear that the actions of chemotherapy are interfered with. (peacehealth.org)
Although research remains incomplete, the idea that people taking chemotherapy should avoid antioxidants is not supported by scientific research. (peacehealth.org)
The chemotherapy drug cisplatin may cause depletion of sodium due to kidney damage which sometimes occurs in people treated with cisplatin. (peacehealth.org)
It remains unclear how important this effect is or if people taking chemotherapy should take taurine supplements. (peacehealth.org)
Acetyl-L-carnitine in the amount of 1,000 mg three times per day for eight weeks has been shown to improve nerve damage (neuropathy) caused by the chemotherapy drug cisplatin. (peacehealth.org)
A deﬁnitive recommendation is still lacking as to whether or when antiox- idants should at all be used in the course of chemotherapy or radiation therapy (17-20). (vdocuments.net)
Curcumin is an up-and-coming drug of natural origin with multi-target properties and it has exhibited efficient anticancer and antifungal activities alone or in combination with conventional chemotherapy drugs and antifungal agents. (video1news.com)

In addition, nanomaterials combined with chemotherapeutic drugs can can induce deleterious oxidative stress in tumor sites, consume GSH and other antioxidant substances to alter cell REDOX homeostasis and achieve anti-tumor effect. (frontiersin.org)
In a study of 42 healthy subjects, another intervention with beta glucan from reishi mushrooms of 225 mg per day for three months demonstrated its antioxidative effects -- enhanced total antioxidant capacity and enzyme activities as well as reduced mild fatty liver condition to normal by suppressing oxidative stress were observed. (greenmedinfo.com)
In normal cell biology, ROS levels increase with a decreasing antioxidant response, resulting in oxidative stress which threatens sperm biology. (mdpi.com)
Oxidative stress has numerous effects, including increased apoptosis, reduced motion parameters, and reduced sperm integrity. (mdpi.com)
They were particularly interested in measuring the change in Sirtuin1, an enzymatic protein (deacetylase), which is important for the survival of cells when they are exposed to oxidative stress, because Sirtuin1 increases the effect of certain antioxidants. (vitalraadet.dk)
In this review we deal in the molecular mechanisms, the epigenetic effects and modulation of the oxidative stress pathway of ketogenic diets, that underlie its possible role, in the treatment of infantile gliomas, as a complementary approach to conventional cancer therapy. (frontiersin.org)
This has especially been true for therapeutic agents that induce oxidative stress as the mechanism of action, as antioxidants may also re- duce the side effects of chemotherapeutic agents. (vdocuments.net)

Titled " Curcumin and its promise as an anticancer drug: An analysis of its anticancer and antifungal effects in cancer and associated complications from invasive fungal infections ", the second study revealed that curcumin may be the perfect way to fight cancers that have a fungal component. (video1news.com)
To date, curcumin's potent antifungal activity against different strains of Candida, Cryptococcus, Aspergillus, Trichosporon and Paracoccidioides have been reported, indicating that curcumin anticancer drugs may also possess an antifungal role, helping cancer patients to resist invasive fungal infection related complications. (video1news.com)
The aim of this review is to discuss curcumin's dual pharmacological activities regarding its applications as a natural anticancer and antifungal agent. (video1news.com)

Previous study revealed that the protective effect of TIGAR in cell survival is mediated through the increase in PPP (pentose phosphate pathway) flux. (nature.com)
To identify the vitamins and dietary micronutrients that exert protective effects against breast cancer and define their mechanism of action, we performed a literature review of in vitro, animal and epidemiological studies and selected the in vitro and animal studies with robust molecular evidence and the epidemiological studies reporting statistically significant inverse associations for a breast cancer-specific protective effect. (vitamindwiki.com)
Studies demonstrating statistically significant inverse associations (epidemiological studies) or robust molecular evidence (animal and in vitro studies) for a protective effect were selected to identify the vitamins and micronutrients to be covered in our concise review. (vitamindwiki.com)
Vitamins and micronutrients associated with no evidence, weak or frequently inconsistent evidence for protective effects against breast cancer were not included in this review. (vitamindwiki.com)
Lipoic acid increases the abundance of other protective antioxidants while improving mitochondrial function and preventing glycation-induced damage in the kidney and blood vessels of those with diabetes-thus defending against diabetic kidney disease, vision loss, and vascular dysfunction. (lifeextension.com)
Experimental sulfur mustard gas poisoning and protective effect of different medicines in rats and rabbits. (cdc.gov)

Vidalista 20 and Vidalista 80mg medicinal drug will let you get rid of your condition quicker. (fashionsdiaries.com)
Medicinal plants used by traditional medical practitioners (TMP) to treat cancers are considered safe when used alone or combined with conventional therapy to ensure their effectiveness and eliminate the toxic effects of orthodox medicines. (who.int)
Using cytotoxic and antioxidant studies, the study attempted to assess some of the commonly used medicinal plants used to cure cancer among Yoruba people in Ogun, Oyo, Osun, and Lagos (South-West, Nigeria). (who.int)

An experience of TiO 2 NPs (20%, 40%, 80% and 100%), as well as mechanisms that instigated momentous alterations in seed germinations, roots interval, shoot lengths, and antioxidant enzymes, were investigated. (nature.com)
Molecular docking analysis for different enzymes involved in aging (collagenase, elastase and hyaluronidase), antioxidant enzymes (superoxide dismutase, glutathione-s-transferase, glutathione peroxidase and catalase) and mitochondrial enzymes (nicotinamide adenine dinucleotide (NAD)+hydrogen (H) dehydrogenase, succinate dehydrogenase, cytochrome c oxidase and adenosine triphosphate synthase) was carried out for epigallocatechin gallate alone (1), withaferin A alone (2), epigallocatechin gallate and withaferin A in combination (3) and a reference molecule. (ijpsonline.com)
Interestingly, (3) displayed a higher binding affinity towards all the aging and antioxidant enzymes as compared to (1), (2) and the references. (ijpsonline.com)
Overall, the results indicate that epigallocatechin gallate and withaferin A, in combination, may potentially inhibit skin-aging, while enhancing antioxidant effects of various enzymes, and warrant further experimental validation. (ijpsonline.com)

Calcitriol enhances the cytotoxic effects of gamma irradiation and certain antioxidants and naturally derived compounds. (jcancer.org)

Reviewing in vivo and in vitro studies on mice and human cell lines using lion's mane (Hericium erinaceus) and tiger tail (Trametes versicolor) mushrooms, treatments showed immunomodulatory, anticancer, anti-inflammatory and neuroregenerative effects. (greenmedinfo.com)
A study done on healthy men showed that daily use of saffron (about 100 mg) could have temporary immunomodulatory effects without any adverse reactions. (simplythegreat.com)

Triphala's chemoprotective potential is seen in coadministration with methotrexate, an antifolate often used as an anticancer and immunosuppressive drug. (jouwweb.nl)
Risk of additive immune system effects with etrasimod has not been studied in combination with antineoplastic, immune-modulating, or noncorticosteroid immunosuppressive therapies. (medscape.com)

Oxygen free radicals are naturally produced by mitochondrial and sperm plasma membrane and have beneficial and detrimental effects that cannot be overlooked. (scialert.net)
However, the over production of oxygen free radicals in sperm membrane decreases the antioxidant defense activity thereby leading to low sperm motility and viability, DNA fragmentation and protein denaturation. (scialert.net)
To counteract the negative effects of excess ROS, spermatozoa and seminal plasma have several mechanisms to neutralize free radicals. (scialert.net)
Therefore, this review will attempt to discuss the relevance of free radicals and antioxidants in spermatozoa production and function. (scialert.net)
Ultraviolet radiation can cause change in physical texture and appearance of the skin via complex signaling cascades, which results in the production of free radicals. (ijpsonline.com)

Calcitriol has been used in a number of clinical trials and it is important to note that sufficient dose and exposure to calcitriol is critical to achieve anti-tumor effect. (jcancer.org)

In addition to its anti-diabetic effects, lipoic acid has a known ability to help combat obesity. (lifeextension.com)

TRO increases radiation sensitivity through G0-G1 arrest or decreases radiation sensitivity through catalase-mediated ROS scavenging according to TRO dose or cell types. (e-roj.org)
chlorambucil decreases effects of adenovirus types 4 and 7 live, oral by pharmacodynamic antagonism. (medscape.com)

Outside of drug metabolism, patients with hormone-related cancers, such as breast and prostate cancers, should steer clear of dietary supplements that can alter levels of testosterone or estrogen, Figg says. (webmd.com)
They include enzymatic and non-enzymatic antioxidant systems which work synergistically to prevent harmful effects of the by-products from aerobic metabolism. (scialert.net)
The research shows that fucoxanthin can have a positive effect on metabolic rate and fat metabolism. (tokibotanicals.com)
Activating PPAR receptors causes somewhat of a systemic effect in the body and acts somewhat as multifaceted mechanism, affecting the metabolism of different nutrients, energy, and biological functions. (tokibotanicals.com)
Inhibition of calcitriol metabolism by 24-hydroxylase promotes growth inhibition effect of calcitriol. (jcancer.org)
chlorambucil will increase the level or effect of gepirone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)

Many oncologists counsel patients against using antioxidant-based dietary supplements - particularly turmeric and green tea extract - while they have radiation therapy and certain chemotherapies. (webmd.com)
It is general knowledge that turmeric being an antioxidant can protect the immune system. (video1news.com)
Turmeric holds much promise because not only does it fight fungal infections without any side effects, but it also has the ability to address a multitude of cancer targets. (video1news.com)

The US Food and Drug Administration (FDA) treats melatonin as a dietary supplement and as such has not approved it for any medical uses. (wikipedia.org)
Popular dietary supplements may, for instance, cancel the effects of a cancer treatment, making it less effective, or increase serious side effects, such as liver toxicity . (webmd.com)
Affect of dietary curcumin and ldl cholesterol on the development of experimentally induced diabetes in albino rat. (fairpeel.com)

Most of antitumor effects was observed at relatively high concentrations (20-50 µM) of TRO, while the clinically achievable concentrations are around 2-5 µM [ 28 , 29 ]. (e-roj.org)
Within the limits of this study, Cimicifugae Rhizoma influenced the viability of stem cells derived from the gingiva, and its direct application onto oral tissues may have adverse effects at high concentrations. (spandidos-publications.com)
In vitro studies found dose- and time-dependent cytotoxic effects of Triphala extracts and constituents on a variety of cultured cancer cell lines, while equal concentrations did not harm cultured normal cells. (jouwweb.nl)

In a study of 18 patients diagnosed with low and intermediate myelodysplastic syndrome, which can lead to leukemia if not managed well, maitake mushroom extract treatment of three milligrams (mg) twice a day for 12 weeks increased immunity, positively affecting neutrophil, monocyte and free radical production. (greenmedinfo.com)
Extracts of the tropical fern Polypodium leucotomos appear to possess beneficial properties for the skin attributed to the presence of numerous compounds within the extract that have antioxidant and photoprotective properties. (jcadonline.com)
Taking proanthocyanidin, a chemical found in grape seed extract, does not reduce breast tissue hardness, pain, or tenderness in people treated with radiation therapy for breast cancer. (medlineplus.gov)
Within the scope of this trial, we investigated the effects of the natural pine bark extract pycnogenol on human fibrosarcoma cells. (spandidos-publications.com)

Nanomaterials can combine multiple treatment methods according to the characteristics of tumor tissue microenvironment to greatly improve the effect of cancer treatment. (frontiersin.org)
Multimodal strategies for tumor diagnosis and treatment based on nanomaterials and nanotechnology represent highly relevant challenges for the future of anticancer treament. (frontiersin.org)
This study investigated the role of TIGAR in DNA damage response (DDR) induced by genotoxic drugs and hypoxia in tumor cells. (nature.com)
Calcitriol elicits anti-tumor effects mainly through the induction of cancer cell apoptosis, cell cycle arrest, differentiation, angiogenesis and the inhibition of cell invasiveness by a number of mechanisms. (jcancer.org)
The broad spectrum anti-tumor effects of calcitriol and analogs are mostly based on inhibition of cancer cell proliferation and invasiveness, induction of differentiation and apoptosis, and promotion of angiogenesis. (jcancer.org)
We underline the need not only to control this type of infection during cancer treatment, especially given the major role of this yeast species in nosocomial infections, but also to find new therapeutic approaches to avoid the pro-tumor effect of this fungal species. (video1news.com)
Therefore, while the presence of Candida albicans should be avoided in cancer patients, consideration should be given to the possibility of including drugs to minimize the risk of Candida albicans being present and its effects, including the creation of pro-tumor micro-environments. (video1news.com)

It's also used as an antiperspirant, a diuretic, and often recommended as an adjuvant drug during cancer and diabetes therapy [ 1 ]. (biomedcentral.com)
Many women do not trust the health care system and will often forgo radiation and drug therapy after breast cancer surgery. (issels.com)
May affect estrogen levels, which could pose an issue for breast or ovarian cancer. (issels.com)
Negates the benefits of certain anti-cancer drugs. (issels.com)
We investigated the effect of TRO on radiation sensitivity in cancer cells in vitro . (e-roj.org)
Jan. 19, 2023 - Cancer dietitian Lisa Cianciotta often finds herself sitting across from a patient who suddenly fishes a bottle of antioxidant supplements from their bag and says, " My friend told me this works really well, " or " I read on the internet that this is supposed to be really good for cancer. (webmd.com)
Drug-supplement interactions are complex, often varying by supplement, cancer, and treatment type, and can do more harm than good. (webmd.com)
But certain supplements appear to affect cancer treatments regardless of other things and should be avoided. (webmd.com)
Antioxidants, in theory, can neutralize this effect, says Skyler Johnson, MD, a radiation oncologist at the Huntsman Cancer Institute at the University of Utah, Salt Lake City. (webmd.com)
Even herbs that don't interfere with how well a cancer drug works, such as stevia , can increase treatment-related side effects, such as nausea and vomiting. (webmd.com)
A phase III randomized, single-blinded trial was conducted in 2009 comparing Calendula to the drug trolamine for prevention of acute dermatitis caused by radiation treatments for breast cancer. (totalhealthmagazine.com)
Similarly, while Triphala increased intracellular reactive oxygen species (ROS) in some cancer cells compared with normal cells, pretreatment with antioxidants inhibited this effect. (jouwweb.nl)
In vitro and animal studies investigating the effects of such micronutrients and vitamins on breast tumours and breast cancer cells were also included in our search. (vitamindwiki.com)
The information provides an admirable sequel to my previous article on the topic, focusing on melatonin's effect on cancer. (innovativemedicine.org)
Consequently, ROS-modulation has emerged as an anticancer strategy with synthesis of various ROS-inducing or responsive agents that target cancer cells. (degruyter.com)
In this report, you will discover how the alpha lipoic acid benefits vital cellular energy while shielding against and possibly reversing the damaging effects of disorders that include diabetes, obesity, cardiovascular disease, neurodegeneration, and cancer. (lifeextension.com)
In this study, we examined the effects of quercetin on cell cycle, viability, and proliferation of cancer cells, either singly or in combination with the microtubule-targeting drugs taxol and nocodazole. (vdocuments.net)
We examined the effect of the cotreatment of cancer cells with the ﬂavonoid quercetin and 2 antimicrotubule drugs, namely, taxol and nocodazole. (vdocuments.net)
Thus, we identify bimodal activity of the ﬂavonoid quercetin, a short-term activity that is cytoprotective against chemotherapeutic drugs and a long-term activity that is inhibitory to cancer cell growth. (vdocuments.net)
The authors also explained that most traditional cancer therapies have serious side effects including damaging patients' immune system, liver and kidneys as well as developing treatment-resistant fungal infections. (video1news.com)
This research provides strong new evidence that vitamin D is the single most effective medicine against cancer, far outpacing the benefits of any cancer drug known to modern science. (naturalnews.com)
Those "race for the cure" cancer walks are a complete scam (they really aren't searching for any way to prevent cancer or cure cancer, they're only searching for new patented drugs to profit from cancer). (naturalnews.com)

However, in some cases, complementary medicines that are recommended for some patients can actually have adverse effects on certain other patients. (issels.com)
The high incidence and limitations of therapeutic strategies underscore the importance of pursuing prevention strategies that lack significant adverse effects. (vitamindwiki.com)
Immunosuppressives may diminish therapeutic effects of vaccines and increase risk of adverse effects (increased risk of infection). (medscape.com)

The ben- eﬁts and dangers of the concomitant use of antioxidants and chemotherapeutic agents has been controversial (17). (vdocuments.net)

By pretreatment with 5 µM TRO radiation sensitivity was increased in HeLa and Me180, but it was decreased in SiHa. (e-roj.org)
This effect was reversed with pretreatment of an antioxidant, N-acetylcysteine (NAC). (jouwweb.nl)

Hence, there is still a need for alternative and well-tolerated compounds that exhibit antineoplastic effects in sarcoma cells. (spandidos-publications.com)

Fucoxanthin also has an effect on something called PGC-1 alpha, which has a powerful effect on mitochondrial health. (tokibotanicals.com)
Pharmaceutical companies are focusing massive resources to develop a drug that targets mitochondrial dysfunction , 1 one of the major causes of the chronic diseases of aging. (lifeextension.com)

The aim of the present study was to evaluate the effects of extracts of Cimicifugae Rhizoma on the morphology and viability of human stem cells derived from gingiva. (spandidos-publications.com)
L. egeregia was regarded as the prototype of the anticancer species due to its profound flavonoid concentration (85.40 µg/mL) and cytotoxicity (9.46 µg/mL) compared to other extracts. (who.int)
Clinical and nonclinical research performed over the past 30 years has demonstrated that extracts of P. leucotomos possess beneficial properties attributed to the presence of numerous compounds with antioxidant and photoprotective properties including p-coumaric, ferulic, caffeic, vanillic, 3,4-dihydroxybenzoic, 4-hydroxybenzoic, 4-hydroxycinnamic, 4-hydroxycinnamoyl-quinic, and chlorogenic acids. (jcadonline.com)
The antioxidant and anti-inflammatory properties of saffron extracts could imply its therapeutic potential for various issues of the nervous system. (simplythegreat.com)

This work provides valuable resources for bioengineering and in vitro synthesis of the natural compounds for medical research and for potential drug development. (biomedcentral.com)
These compounds can postpone dangerous microorganisms and viruses and defend your physique from dangerous UV radiation. (fashionsdiaries.com)
Saffron's photoprotective effects may also be due to its other phenolic compounds, such as tannic, gallic, caffeic, and ferulic acids. (simplythegreat.com)

Of these, rutin, also known as vitamin P or rutoside, has been explored for a number of pharmacological effects. (fuqna.com)
An increasingly popular strategy is pharmaconutrition, which combines a tailored pharmacological treatment with a diet designed to synergize the effects of drugs. (frontiersin.org)

When taken orally, P. leucotomos provides some degree of protection against the harmful effects of ultraviolet radiation,[3,4] thereby helping to minimize the photoaging effects of sunlight, including hyperpigmentation and textural changes. (jcadonline.com)
Given the central role that ultraviolet radiation (UVR) plays in the pathogenesis of cSCC, methods aimed at decreasing UVR exposure form the cornerstone of cSCC prevention. (medscape.com)

Preclinical evidence demonstrates that certain carotenoids may have potent antitumor effects. (simplythegreat.com)

Both SOD and catalase may decrease radiation sensitivity via reactive oxygen species (ROS) scavenging. (e-roj.org)

Numerous in vitro and animal model studies using quercetin alone or quercetin in combination with other bioactive com- pounds have shown the anticancer activities of the compound (8-15). (vdocuments.net)

The therapy of choice involves surgical resection with a wide margin of healthy tissue, usually followed by radiation treatment in order to decrease local recurrence ( 2 , 3 ). (spandidos-publications.com)
The recently published EORTC 62012 trial which involved 455 patients with locally advanced, unresectable or metastatic high-grade soft tissue sarcomas concluded that an intensified therapy with doxorubicin and ifosfamide is not suitable for palliation of advanced soft tissue sarcomas because of the severe side-effects and should only be used when the specific goal is tumour shrinkage ( 13 ). (spandidos-publications.com)

Most animal studies show saffron to exhibit antioxidant, anticancer, anti-inflammatory, and anti-hyperlipidemic effects in treating gastrointestinal disorders. (simplythegreat.com)

Reishi (in Japanese) or lingzhi (in Chinese) mushrooms are well known in Asia for their anticancer properties. (greenmedinfo.com)
Moreover, its acidic properties can affect the operation of the microbiome. (fashionsdiaries.com)
however, its known antioxidant and anti-inflammatory properties and demonstrated effectiveness for melasma support its use for treating this condition. (jcadonline.com)
Epigallocatechin gallate and withaferin A were analyzed for their physiochemical properties, drug-likeness and human intestinal absorptivity using Data Warrior, Molsoft and SwissADME (boiled egg model) respectively. (ijpsonline.com)
One rat study links the possible wound healing properties of saffron to its antioxidant and anti-inflammatory activity. (simplythegreat.com)
Due to its antioxidant properties, saffron helps maintain healthy arteries and blood vessels. (simplythegreat.com)

Grape contains flavonoids, which can have antioxidant effects. (medlineplus.gov)

On the other hand, TRO shares a common structure with vitamin E which has a potent antioxidant property [ 19 ]. (e-roj.org)
With NHV's Stimmune , your kitty will get potent immune supporting herbs that help support your cat with food allergy reactions, as well as reactions related to fleas, dermatitis, insect bites, diet, and exposure to chemicals and drugs. (nhvpethealth.com)

Kamagra oral jelly has many beneficial effects on the health of men. (fashionsdiaries.com)
They might help prevent heart disease and have other beneficial effects. (medlineplus.gov)
The spice interacts with the cholinergic and dopaminergic systems, which may have beneficial effects in the case of Alzheimer's or Parkinson's. (simplythegreat.com)

Side effects from melatonin supplements are minimal at low doses for short durations (in the studies reported about equally for both melatonin and placebo). (wikipedia.org)
These drug-supplement interactions can be hard to pinpoint, given that more than two-thirds of doctors don't know their patients are using supplements. (webmd.com)
Note that these astonishing effects were achieved on what many nutritionists consider to be a low dose of vitamin D . Exposure to sunlight, which creates even more vitamin D in the body, was not tested or considered, and the quality of the calcium supplements was likely not as high as it could have been (it was probably calcium carbonate and not high-grade calcium malate, aspartate or similar forms). (naturalnews.com)

5] P. leucotomos may owe its ability to help in preventing the photoaging process specifically by maintaining the structural integrity of the extracellular matrix that typically is affected by UV damage through increased matrix metalloproteinase expression and inhibition of collagen synthesis. (jcadonline.com)

SOR), hydrogen peroxide, and 2, 2-Diphenyl-2-picrylhydrazyl (DPPH) radical activity by a model (most biological y active) of the anticancer plant was also evaluated. (who.int)
The anticancer model's overal antioxidant activity (34.72 µg/mL) was slightly lower than quercetin (30.44 µg/mL) but higher than ascorbic acid (41.68 µg/mL). (who.int)
Additionally, molecular dynamics simulations were performed to estimate stability and flexibility of best complexes, while collagenase activity colorimetric assay was carried out to study the effects of (1), (2) and (3) on collagenase. (ijpsonline.com)
We hypothesized an additive or a synergistic effect with this drug-ﬂavonoid com- bination, but unexpectedly, quercetin protected cells from the activity of these antimicrotubule drugs and sustained the via- bility of the cells. (vdocuments.net)
This effect could most likely be attributed to its antioxidant activity. (simplythegreat.com)

Drug-diet interactions among an- tioxidants and classes of drugs that act through nonoxidative mechanisms is not well known. (vdocuments.net)
Diet can affect oral health via numerous mechanisms. (medscape.com)

Study of some toxic effects of sulfur mustard gas on broiler chickens. (cdc.gov)

A 2001 study found that because Calendula has profound anti-inflammatory and anti-bacterial effects, it is beneficial for acne. (totalhealthmagazine.com)

The change of radiation sensitivity by combined with TRO is not dependent on the PPARγ expression level. (e-roj.org)
In addition, PPARγ agonist is of particular interest as a potential anticancer agent because of its effect on cellular differentiation, proliferation, and tumorigenesis [ 3 , 4 ]. (e-roj.org)
PPAR receptors and activation is a fairly new area of research showing tons of promise, and is the theme of new drugs. (tokibotanicals.com)
Luckily, this effect doesn't occur with natural PPAR activators such as fucoxanthin. (tokibotanicals.com)

Triphala protected against ionizing radiation with peritoneal or oral dosing in animal studies. (jouwweb.nl)
Studies on mice show that even at astronomical doses of 300 mg per day for two years, there were no side effects. (innovativemedicine.org)
Several other promising scientific studies now show that lipoic acid has a beneficial effect on a number of the factors involved in metabolic syndrome: it reduces triglyceride levels, lowers cholesterol, improves fasting plasma glucose, and causes weight loss in rodent models of obesity. (lifeextension.com)

Since, ROS is essential for the normal sperm physiology, rationale use of antioxidants is advocated. (scialert.net)

In addition to preventing many harmful effects associated with sunlight exposure, orally administered Polypodium leucotomos also appears to provide adjunctive benefits in treating vitiligo, melasma, and may have the potential to help with postinflammatory hyperpigmentation. (jcadonline.com)

This could decrease the effects of cyclosporine. (medlineplus.gov)

In with carcinogenic effects (e.g. benzene, chromates, aromatic the years up to 1930, major scientific progress occurred in the fun- damental principles of protection, which included substitution, enclosure and ventilation (Luxon, 1984 ). (cdc.gov)

Treatment of MCF-7 cells with pifithrin α, an inhibitor of p53, reversed Triphala's effects and, with similar observations in other cell lines, confirms the role of p53 in Triphala-induced apoptosis. (jouwweb.nl)

The TLB also demonstrated the presence of quercetin, with a dose-dependent antioxidant property. (who.int)
Quercetin also partially restored drug-induced loss in viability of treated cells for up to 72 h. (vdocuments.net)

Epirubicin, a DNA damaging anticancer agent and CoCl 2 , which was used to imitate hypoxia condition, was applied to induce DNA damage in TIGAR knockdown HepG2 cells. (nature.com)

A 2019 review found that while melatonin may improve sleep in minimal cognitive impairment, after the onset of Alzheimer's disease it has little to no effect. (wikipedia.org)

Side effects of melatonin are rare but may occur in 1 to 10 patients in 1,000. (wikipedia.org)
Use of the drugs fiercely divides medical opinion with proponents arguing the benefits in reducing the risk of heart attacks and stroke far outweigh the risk of side effects which include severe muscle pain, impotence, cataracts, mental impairment, diabetes, fatigue and liver dysfunction. (infiniteunknown.net)
The limitations of current treatment strategies include: i) resistance to drug treatment, ii) significant side-effects and iii) cost. (vitamindwiki.com)
There are no side effects. (innovativemedicine.org)
Some other side effects might include cough, dry mouth, and headache. (medlineplus.gov)

Anatomy21

Organisms11

Diseases17

Chemicals and Drugs123

Analytical, Diagnostic and Therapeutic Techniques and Equipment41

Phenomena and Processes40

Disciplines and Occupations5

Technology, Industry, Agriculture8

Information Science3

Health Care14

Chemotherapy25

Oxidative7

Antifungal3

Protective6

Medicinal3

Enzymes4

Certain antioxidants1

Immunomodulatory2

Immunosuppressive2

Free radicals5

Achieve anti-tumor effect1

Anti-diabetic1

Decreases2

Metabolism6

Turmeric3

Dietary3

Concentrations3

Extract4

Tumor7

Cancer22

Adverse effects3

Concomitant1

Pretreatment2

Antineoplastic1

Mitochondrial2

Extracts4

Compounds3

Pharmacological2

Ultraviolet radiation2

Antitumor effects1

Species1

Bioactive1

Therapy2

Exhibit1

Properties6

Flavonoids1

Potent2

Beneficial effects3

Supplements3

Extracellular matrix1

Activity5

Mechanisms2

Toxic1

Profound1

PPAR4

Studies3

Sperm1

Harmful effects1

Decrease1

Carcinogenic1

Apoptosis1

Quercetin2

Induce1

Alzheimer's1

Side5