• Here, we investigated the correlation between microRNA-21 expression and hepatic arterial infusion chemotherapy with 5-fluorouracil and pirarubicin (HAIC) for hepatocellular carcinoma (HCC). (nih.gov)
  • Which alters the feeding of cancer patients, contributing to the anorexia, weight loss and malnutrition, which leads to a prognostic impact in a lower patient response to chemotherapy, radiotherapy and surgical treatment as well as increased toxic effects, impacting treatment discontinuation and therefore, morbidity and survival of patients. (clinicaltrials.gov)
  • Angiostatic chemotherapy consisted of trofosfamide (50 mg) administered orally 3 times daily beginning on the 15th day after the start of molecularly targeted therapy. (uni-regensburg.de)
  • Furthermore, we explored the possibility of creating an improved prognostic tool by combining the MIPI with information on molecular markers.SOX11 was shown to significantly add prognostic information to the MIPI, but in multivariate analysis TP53 was the only significant independent molecular marker.Based on these findings, we propose that TP53 and SOX11 should routinely be assessed and that a combined TP53/MIPI score may be used to guide treatment decisions. (nih.gov)
  • Taken together, our findings demonstrate that microRNA-21 is a chemotherapy responsive microRNA and can serve as a prognostic biomarker for HCC patients undergoing HAIC. (nih.gov)
  • BACKGROUND: Combined treatment approaches targeting tumor cells as well as stromal cells may control chemorefractory malignancies. (uni-regensburg.de)
  • The objective of this study is to describe the threshold of perception and recognition of basic tastes in patients with NSCLC before treatment with platin and paclitaxel-based chemotherapy and after the second cycle, and analyze the effect in the developement of dysgeusia, as well as the association between these and the nutritional status and quality of life. (clinicaltrials.gov)
  • After chemotherapy, 75.9%, 67.9%, 59.3% and 51.7% of the patients showed low antibody titers that would be unlikely to protect against exposure to measles, rubella, hepatitis B and mumps, respectively. (scielo.br)
  • PURPOSE: The combination of sorafenib with chemotherapy is well-tolerated and is associated with encouraging response rates in several malignances. (mendeley.com)
  • Antibody levels against hepatitis B, rubella, measles and mumps vaccine antigens were evaluated in 33 children after completing chemotherapy (before and after vaccine booster doses) and the results were compared to the data of 33 healthy children matched for gender, age and social class. (scielo.br)
  • These results suggest IRS1 enhances sensitivity to chemotherapy in part through Annexin A2. (biomedsearch.com)
  • The combined TP53/MIPI show significant (P = 0·006) separation between low and intermediate risk groups in relation to (G) OS and identifies a high risk group with decreased (H) EFS. (nih.gov)