• 2) Antilymphocyte Globulin (ALG) . (nanomedicine.com)
  • ALG is produced by immunizing a large animal such as a horse with human lymphocytes, then purifying the gamma globulin fraction of the serum. (nanomedicine.com)
  • Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease. (1library.co)
  • [ 1 ] Recipients were treated with intensive conventional immunosuppression , including combinations of prednisone , azathioprine , and antilymphocyte globulin. (medscape.com)
  • the action of immunosuppressants (cyclosporin, antilymphocyte sera, monoclonal antibodies against Tlymphocytes). (wikipedia.org)
  • Antithymocyte immunoglobulin from rabbit serum is classified in L04AA04. (whocc.no)
  • Two subgroups of SSD(+) and SSD(-) patients that had received ATG induction treatment were then assessed for total anti-ATG, anti-Neu5Gc, and anti-Gal antibodies using ELISA assays on sera before and after transplantation. (nih.gov)
  • sera from children were tested for antibodies to viral capsid antigens of epstein-barr virus. (liverpool.ac.uk)
  • However, ATGs can induce immune complex diseases, including serum sickness disease (SSD). (nih.gov)
  • Steroids are generally ineffective, though are often used to combat serum sickness caused by ATG use. (webdicine.com)
  • The evidence for the interaction of 2 subpopulations of T cells, short-lived cells sensitive to adult thymectomy (T1 cells), and long-lived recirculating cells, sensitive to the action of antilymphocyte serum (T2 cells) in the induction of helper cells is presented. (ox.ac.uk)
  • Pop, A, "Production of Laboratory Animals for the Production of Serums and Vaccines," Arch Roum Path Exp Mocrobiol, 1967, 23:423-430. (currenthealthscenario.com)
  • We analyzed data from a cohort of 889 first kidney graft recipients with ATG induction (86 with SSD [SSD(+)] and 803 without SSD [SSD(-)]) from the Données Informatisées et Validées en Transplantation data bank. (nih.gov)
  • Amplifier T cells responsible for enhancement of the antibody response to type III pneumococcal polysaccharide have been shown to be resistant to the effects of antilymphocyte serum (ALS) given at the time of immunization, a treatment that eliminates suppressor T cell activity. (johnshopkins.edu)
  • Rapid kidney allograft failure in patients with polyoma virus nephritis with prior treatment with antilymphocyte agents. (mcw.edu)
  • Lymphoprep™ is a ready-made, sterile and endotoxin tested density gradient medium recommended for the isolation of pure lymphocyte suspensions for tissue typing, anti-lymphocyte sera and immunological research. (transcriptionfactor.org)
  • positive serum tests for infectious mononucleosis (im) unaccompanied by the clinical syndrome or blood changes characteristic of the disease were detected in 39/177 (22%) mentally subnormal patients investigated with three different commercially available im slide tests. (liverpool.ac.uk)
  • Although antilymphocyte serum was used in the treatment of chronic lymphocytic leukemia and in T-cell and B-cell lymphomas, resulting in temporary decreases in lymphocyte counts or lymph node size, newer humoral immunotherapeutic modalities have been developed. (msdmanuals.com)
  • production of interferon or interferon-like susbstances in eb3 cultures after inoculation with human serum containing australia antigen]. (liverpool.ac.uk)
  • the action of immunosuppressants (cyclosporin, antilymphocyte sera, monoclonal antibodies against Tlymphocytes). (wikipedia.org)
  • Serum that contains antibodies. (umassmed.edu)
  • Serum containing GAMMA-GLOBULINS which are antibodies for lymphocyte ANTIGENS . (bvsalud.org)
  • Antilymphocyte antibodies include polyclonal preparations, such as equine antithymocyte globulin (ATGAM) and rabbit antithymocyte globulin (Thymoglobulin), and the monoclonal antibody preparations muromonab-CD3 (OKT3) and anti-CD52 (Alemtuzumab). (pharmapedia.pk)
  • Antilymphocyte antibodies act by lymphodepletion, as well as by interactions with cellular receptors. (pharmapedia.pk)
  • Autoantibodies (autoAbs) to cell-surface molecules, including antilymphocyte antibodies, are often detected in the sera of patients with systemic autoimmune diseases such as systemic lupus erythematosus (SLE). (biomedcentral.com)
  • METHODS IgG anti-P antibodies in the sera of 267 patients with CTDs and 31 healthy subjects were analysed by immunoblotting performed on cytoplasmic extract of Raji cells. (bmj.com)
  • A close association of IgG antibodies with P proteins and with cardiolipin was seen in lupus sera (p=0.0009, odds ratio 18.33). (bmj.com)
  • Anti-P antibodies from 9 of 12 anti-P lupus serum samples could be affinity purified and none of the affinity purified fractions cross reacted with ELISA plate coated cardiolipin. (bmj.com)
  • Anti-P antibodies are strongly clustered with IgG anticardiolipin antibodies in lupus sera, even if they are independently elicited. (bmj.com)
  • Twenty-two patients with aplastic anemia were treated with antilymphocyte serum or antithymocyte globulin at Vanderbilt University and affiliated hospitals from 1980 to 1986. (nih.gov)
  • Twenty patients received antilymphocyte serum initially while two patients received antithymocyte globulin. (nih.gov)
  • Fifteen patients received fluoxymesterone 10 mg by mouth three times a day with antilymphocyte serum, and all received prednisone during the course of antilymphocyte serum or antithymocyte globulin. (nih.gov)
  • Eight patients with no initial response and a patient who experienced a relapse after a complete response were re-treated with either antithymocyte globulin (six) or antilymphocyte serum (three), with four of nine patients (44 percent) having a response (three complete responses, one partial response). (nih.gov)
  • ALG (Thymoglobulin) and antithymocyte globulin (ATG) are less commonly used antilymphocyte antibody preparations. (pharmapedia.pk)
  • Antilymphocyte globulin (ALG) and antithymocyte globulin (ATG) are produced by extracting immunoglobulins from animals (usually horse or rabbit) that have been immunized with human lymphocytes or thymocytes, respectively. (pharmapedia.pk)
  • Opsonizing activity of anti-human lymphocyte serum. (jax.org)
  • 8. Combined host-conditioning with CTLA4-Ig, tacrolimus, anti-lymphocyte serum, and low-dose radiation leads to stable mixed hematopoietic chimerism. (nih.gov)
  • 11. A partial conditioning strategy for achieving mixed chimerism in the rat: tacrolimus and anti-lymphocyte serum substantially reduce the minimum radiation dose for engraftment. (nih.gov)
  • Although antilymphocyte serum was used in the treatment of chronic lymphocytic leukemia and in T-cell and B-cell lymphomas, resulting in temporary decreases in lymphocyte counts or lymph node size, newer humoral immunotherapeutic modalities have been developed. (msdmanuals.com)
  • LymphoprepTM can be used for the preparation of pure lymphocyte suspensions for tissue typing, antilymphocyte sera, and immunological research. (microsensbp.com)
  • Antilymphocyte immunoglobulin from horse serum is classified in L04AA03. (whocc.no)
  • Antithymocyte immunoglobulin from rabbit serum is classified in L04AA04. (whocc.no)
  • A characteristic feature of patients with connective tissue diseases (CTDs) is detection of high levels of autoantibodies to intracellular "self" antigens in the serum. (bmj.com)
  • Delayed cases of antibody mediated rejection present as an acute rise in the serum creatinine with or without graft tenderness. (upmc.com)
  • Of these antilymphocyte agents, Thymoglobulin is currently predominant, and the use of the others is either rare or of historic interest. (pharmapedia.pk)
  • Assay for the immunosuppressive capacity of antilymphocyte serum. (jax.org)
  • Most centers include induction therapy with an antilymphocyte agent in their immunosuppressive regimens. (medscape.com)
  • PMID- 5157696 TI - [IgA in the gastric content and in the serum of eutrophic and malnourished infants]. (nih.gov)
  • Commonly observed side effects include allergic reactions, serum sickness, fever, and thrombocytopenia, as with OKT3 and other systemically infused immunoglobulins. (pharmapedia.pk)
  • Immune Sera" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Immune Sera" by people in this website by year, and whether "Immune Sera" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Immune Sera" by people in Profiles. (umassmed.edu)
  • Clinico-prognostic implications of increased levels of soluble CD54 in the serum of B-cell chronic lymphocytic leukemia patients. (haematologica.org)
  • Careful attention to fasting blood glucose levels and upward trends in serum amylase, lipase, and glucose levels may be useful in the clinical detection of rejection, but are usually not apparent until late in the rejection process. (medscape.com)
  • The use of antilymphocyte induction regimens has declined precipitously with time. (pharmapedia.pk)
  • Using six recombinant proteins (F2-F7) for LRP2 and one for CD69, we detected autoAbs to LRP2 in sera of patients with rheumatoid arthritis (RA), systemic lupus erythematosus, Behçet's disease, systemic sclerosis, and osteoarthritis and then mapped autoepitopes by Western blotting. (biomedcentral.com)
  • Granoff DM, Welsch JA, Ram S. Binding of complement factor H (fH) to Neisseria meningitidis is specific for human fH and inhibits complement activation by rat and rabbit sera. (umassmed.edu)
  • Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci. (umassmed.edu)
  • In addition, iron chelation may be required in chronically transfused patients who develop elevated serum ferritin levels above 1000 µg/L. (medscape.com)
  • Effective and ineffective antilymphocyte sera correlation of in vitro " by R C. Davis, S R. Cooperband et al. (jax.org)
  • Effective and ineffective antilymphocyte sera correlation of in vitro tests with potency of early antisera. (jax.org)
  • Multiple epitopes on LRP2 were recognized by most of the anti-LRP2 + serum samples. (biomedcentral.com)
  • A major limitation of all polyclonal antilymphocyte preparations is batch-to-batch heterogeneity, which results in unpredictable side effects and more importantly, variable efficacy. (pharmapedia.pk)