• The two cases reported here provide, to the best of the authors' knowledge, the first description of the pathology and viral antigen distribution of lethal respiratory disease in domestic cats after natural pandemic (H1N1) 2009 influenza virus infection, probably transmitted from humans. (oregonstate.edu)
  • Even when a virus cannot be cultured, provided gene sequence is available, it is possible to rapidly respond to emerging viruses and new viral strains of existing pathogens. (prospecbio.com)
  • Mammalian Orthoreoviruses The only orthoreovirus to not produce syncytia, mammalian orthoreoviruses have the capability of infecting all mammals, but do not cause disease, except in young populations enabling them to be studied frequently as a model for viral replication and pathogenesis. (wikipedia.org)
  • They further suggest that structural features of viral GPs or coevolutionary adaptation of the virus's GP to the host's naive B cell repertoire, or both, may critically limit nAb kinetics and improvement of vaccine efficacy. (jci.org)
  • We analyzed the nAb response to each of the 2 recombinant and parent viruses in infected mice and found that nAb kinetics were solely determined by the viral surface GP and not by the virus backbone. (jci.org)
  • Systematic studies of immune responses to microbial antigens in vivo may be performed during vaccination. (nih.gov)
  • We observed augmented innate and adaptive immune responses in pSS following viral antigen exposure suggesting an underlying hyper-responsiveness to immune challenges, supporting a role for infections driving the immunopathology and acting as environmental risk factor for pSS. (nih.gov)
  • These findings suggest that the immune reaction and subsequent tissue damage of herpes-associated erythema multiforme are due to the presence of herpes antigens in the skin. (annals.org)
  • Microbix Biosystems (TSX:MBX) agreed to supply an existing long-term customer with an increasing quantity of its viral antigen products over the next five years, with an option to extend that term. (biotuesdays.com)
  • The immunodot blot test was used to identify African swine fever virus (ASFV) antigens in the hemolymph from soft ticks ( Ornithodoros coriaceus ) fed on ASFV-infected pigs. (ajtmh.org)
  • The immunodot blot test was sensitive and specific for ASFV antigens and has potential field application. (ajtmh.org)
  • Our data may also explain the elevated serum GrB levels found in the early phase of various viral diseases. (jimmunol.org)
  • On 1 November 2017, the Norwegian Medicines Agency granted Pharmaq authorisation to produce viral antigens at their new facility in Kløfta. (wfga.net)
  • Polyprotein is processed by host signalases, resulting in E3, E2 & E1 forming viral hetero-trimeric spikes. (prospecbio.com)