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  • Aspergillus
  • Septate hyphae were observed on histopathology of the laryngeal lesion, which was further confirmed as Aspergillus fumigatus after extraction of fungal DNA from formalin fixed paraffin embedded tissue (FFPET) and sequencing. (springer.com)
  • Sera were successively screened for galactomannan antigen and for Aspergillus fumigatus specific nucleic acid targets.Although bronchoalveolar lavage proved negative in 93 % of controls it did not detect IPA in 86 % of the cases.The data from this pilot-study demonstrate that the consideration of standard clinical methods combined with biomarker testing improves the capacity to make early and more accurate diagnostic decisions. (nih.gov)
  • Sera were successively screened for galactomannan antigen and for Aspergillus fumigatus specific nucleic acid targets. (nih.gov)
  • Fungal colonization with Aspergillus worsens excercise tolerance in HP patients, whereas Candida doesn't impact on HP. (ersjournals.com)
  • The genus Aspergillus comprise different saprophytic fungal species with a high environmental prevalence that, under specific circumstances, might infect humans and other animals causing different infectious diseases. (frontiersin.org)
  • ABPA is one of several disorders caused by Aspergillus fumigatus , other types of aspergillus or other fungal species. (clinicaladvisor.com)
  • Pathogens
  • Characterisation of the antigen recognised by one of these MAbs (4D1) revealed an immunogenic glycoprotein that was almost exclusively expressed in yeast cells of numerous P. marneffei isolates and undetected in other medically important fungal pathogens. (aspergillus.org.uk)
  • spores
  • Few regulatory occupational exposure limits have been adopted for bioaerosol agents, but proposed health-based exposure limits for endotoxins and fungal spores can be used. (cdc.gov)
  • Granulomatosis caused by fungal spores of a soil saprophyte is a newly recognized pulmonary complication of intravenous drug addiction. (annals.org)
  • Assays
  • This glycoprotein antigen has been detected by MAb 4D1 in both sera and urine samples from patients with suspected P. marneffei infection by assays such as immuno dotblot and Western immunoblot. (aspergillus.org.uk)
  • The VBI researchers will also create a series of fungal knockout mutants for specific genes that will be evaluated in in vitro and in vivo immunological assays during the course of the project. (eurekalert.org)
  • Genera
  • Epichloae endophytes of family Clavicipitaceae (comprising genera Epichlo├ź and Neotyphodium ) are fungal symbionts of Pooideae grasses. (springer.com)
  • allergic
  • What is the protocol for immunotherapy to treat allergic fungal sinusitis (AFS)? (medscape.com)
  • Later, both fungal and nonfungal antigens to which the patient was found to be allergic were included in the treatment mix. (medscape.com)
  • 30 mm in diameter occurring 24-48 h after an injection) are said to be more common when administering immunotherapy for molds than for other antigens, this has not been the reported experience in treating patients with allergic fungal sinusitis (AFS). (medscape.com)
  • On the basis of experience, administration of immunotherapy to patients with allergic fungal sinusitis (AFS) is currently recommended for the same duration as that recommended for patients with allergies in general, ie, 3-5 years. (medscape.com)
  • Severe asthma with fungal sensitization predominates in the population suffering from allergic asthma, to which there is no cure. (hindawi.com)
  • Herein, we hypothesized that mannan from Saccharomyces cerevisiae would dampen the characteristics of fungal allergic asthma by altering the pulmonary immune responses. (hindawi.com)
  • measurement
  • Using wild-type and transgenic mice expressing the human mannose receptor on smooth muscle cells, we explored the outcome of mannan administration during allergen exposure on the pathogenesis of fungal asthma through measurement of cardinal features of disease such as inflammation, goblet cell number, and airway hyperresponsiveness. (hindawi.com)
  • disease
  • Most of them are not detrimental to human body, but some will lead to fungal disease. (selfgrowth.com)
  • In initial studies, only immunotherapy for positive fungal antigens was administered for the first 6 months to be certain that any effects (either positive or negative) on the disease process were caused by the administration of fungal antigens. (medscape.com)
  • This may be a clue that fungal antigens could be one environmental trigger for the disease. (ucsd.edu)
  • Test
  • Guinea pigs infected with Trichophyton mentagrophytes developed a cutaneous fungal lesion and became skin test positive to fungal antigen (trichophytin). (semanticscholar.org)
  • The cutaneous fungal lesion, while thought to be a cell-mediated response, differed histologically from the skin test site. (semanticscholar.org)
  • Basophils were not demonstrated in biopsies of cutaneous fungal lesions, whereas basophils were numerous in biopsies of trichophytin skin test sites. (semanticscholar.org)
  • The antigens for which they test and treat are listed in Table 5 below. (medscape.com)
  • development
  • The VBI team will produce a set of recombinant fungal proteins that will be used to dissect the different molecular steps involved in the development and progression of CRS. (eurekalert.org)
  • In: Osiewacz HD (ed) Molecular biology of fungal development. (springer.com)